EP2874908B1 - Emballage pour films contenant une dose unitaire d' une substance active ainsi que le procédé pour fabriquer cet emballage - Google Patents
Emballage pour films contenant une dose unitaire d' une substance active ainsi que le procédé pour fabriquer cet emballage Download PDFInfo
- Publication number
- EP2874908B1 EP2874908B1 EP13736824.7A EP13736824A EP2874908B1 EP 2874908 B1 EP2874908 B1 EP 2874908B1 EP 13736824 A EP13736824 A EP 13736824A EP 2874908 B1 EP2874908 B1 EP 2874908B1
- Authority
- EP
- European Patent Office
- Prior art keywords
- packaging
- material element
- sealing
- incision
- item
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000000034 method Methods 0.000 title claims description 8
- 238000004519 manufacturing process Methods 0.000 title claims description 4
- 239000013543 active substance Substances 0.000 title description 7
- 239000005022 packaging material Substances 0.000 claims description 67
- 238000007789 sealing Methods 0.000 claims description 61
- 238000004806 packaging method and process Methods 0.000 claims description 32
- 239000004480 active ingredient Substances 0.000 claims description 7
- 238000005452 bending Methods 0.000 claims description 4
- 235000012431 wafers Nutrition 0.000 claims description 3
- 239000004831 Hot glue Substances 0.000 claims description 2
- 239000000853 adhesive Substances 0.000 claims description 2
- 230000001070 adhesive effect Effects 0.000 claims description 2
- 239000006185 dispersion Substances 0.000 claims description 2
- 239000012173 sealing wax Substances 0.000 claims description 2
- 239000010410 layer Substances 0.000 description 35
- 239000010408 film Substances 0.000 description 17
- 229910052751 metal Inorganic materials 0.000 description 7
- 239000002184 metal Substances 0.000 description 7
- 238000009792 diffusion process Methods 0.000 description 4
- 239000002552 dosage form Substances 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 239000011505 plaster Substances 0.000 description 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 239000011888 foil Substances 0.000 description 3
- 229910052760 oxygen Inorganic materials 0.000 description 3
- 239000001301 oxygen Substances 0.000 description 3
- 229920000642 polymer Polymers 0.000 description 3
- 229910052782 aluminium Inorganic materials 0.000 description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000000825 pharmaceutical preparation Substances 0.000 description 2
- 229940127557 pharmaceutical product Drugs 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 230000003313 weakening effect Effects 0.000 description 2
- 238000003466 welding Methods 0.000 description 2
- 239000004820 Pressure-sensitive adhesive Substances 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 231100001261 hazardous Toxicity 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000006186 oral dosage form Substances 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 239000011241 protective layer Substances 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B11/00—Wrapping, e.g. partially or wholly enclosing, articles or quantities of material, in strips, sheets or blanks, of flexible material
- B65B11/50—Enclosing articles, or quantities of material, by disposing contents between two sheets, e.g. pocketed sheets, and securing their opposed free margins
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B61/00—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages
- B65B61/18—Auxiliary devices, not otherwise provided for, for operating on sheets, blanks, webs, binding material, containers or packages for making package-opening or unpacking elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
- B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
- B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
- B65D75/52—Details
- B65D75/58—Opening or contents-removing devices added or incorporated during package manufacture
- B65D75/5805—Opening or contents-removing devices added or incorporated during package manufacture for tearing a side strip parallel and next to the edge, e.g. by means of a line of weakness
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
- B65D75/52—Details
- B65D75/58—Opening or contents-removing devices added or incorporated during package manufacture
- B65D75/5827—Tear-lines provided in a wall portion
Definitions
- film-shaped oral dosage forms also known as oral thin films (OTF) or wafers, which consist of only one polymer layer (hereinafter called “film”).
- the invention is therefore based on the object to provide a generic single-dose packaging, which improves the embodiments described above.
- the diffusion of substances into the interior of the packaging should be prevented.
- the invention thus provides that the end points of the cuts are at least as far away from the cavity as the maximum width of the remaining sealing seams.
- Each package has sealed seams on at least three sides that take into account a width to prevent or prevent diffusion for the period of maximum storage.
- the said cuts have a sufficient distance along a cutting line to the introduced film or plaster, so that no damage occurs during tearing.
- a suitable distance M3 is shown.
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Composite Materials (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Packages (AREA)
- Wrappers (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Bag Frames (AREA)
- Basic Packing Technique (AREA)
Claims (10)
- Emballage (1) pour films ou pansements (2) contenant une dose unitaire de substance active, comprenant un élément d'emballage supérieur (3) et un élément d'emballage inférieur (4) qui sont connectés l'un à l'autre au moyen d'une surface de scellage ou d'un cordon de scellage (5) périphériques, de telle sorte qu'une cavité (6) entourée de tous les côtés soit formée pour recevoir le film ou le pansement (2),i.) l'élément d'emballage supérieur (3) et l'élément d'emballage inférieur (4) présentant, dans la région de la surface de serrage ou du cordon de serrage (5), à chaque fois au moins une découpe (7, 8), celles-ci étant en coïncidence, etii.) au moins une découpe (7, 8) étant intersectée par une ligne de pliure ou de flexion (10), caractérisé en ce queiii.) la découpe (7) dans l'élément d'emballage supérieur (3) et la découpe coïncidente (8) dans l'élément d'emballage inférieur (4) sont réalisées de telle sorte que le point d'extrémité respectif (15, 16) des découpes (7, 8) présente une distance (M1) à la cavité (6) qui correspond au moins à la largeur (M2) du cordon de scellage (5).
- Emballage (1) selon la revendication 1, caractérisé en ce que
la découpe (7) et la découpe (8) sont orientées à angle droit par rapport à l'arête extérieure la plus proche (6a) de la cavité (6). - Emballage (1) selon la revendication 1,
caractérisé en ce que
l'élément d'emballage supérieur (3) et l'élément d'emballage inférieur (4) sont réalisés d'une seule pièce et forment une arête de flexion (17). - Emballage (1) selon la revendication 1,
caractérisé en ce que
la couche extérieure supérieure (11) et/ou la couche extérieure inférieure (12) sont réalisées de manière à pouvoir être imprimées. - Emballage (1) selon l'une quelconque des revendications 1 à 4,
caractérisé en ce que
la surface de scellage ou le cordon de scellage (5) ne sont pas pelables. - Emballage (1) selon l'une quelconque des revendications 1 à 5,
caractérisé en ce que
chaque élément d'emballage (3, 4) présente une couche extérieure (11, 12) et une couche métallique (13, 14) et au moins l'un des deux éléments d'emballage (3, 4) présente une couche de scellage (9). - Emballage (1) selon la revendication 6,
caractérisé en ce que
la couche de scellage est choisie parmi un adhésif thermofusible, un vernis de scellage, des dispersions de scellage ou des adhésifs. - Procédé de fabrication d'un emballage (1) pour films ou pansements contenant une dose unitaire de substance active, comprenant les étapes suivantesi.) fourniture d'un élément d'emballage supérieur (3) et d'un élément d'emballage inférieur (4), qui sont connectés l'un à l'autre au moyen d'une surface de scellage ou d'un cordon de scellage (5) périphériques, de telle sorte qu'une cavité (6) entourée de tous les côtés soit formée pour recevoir les films,ii.) au moins une découpe (7, 8) étant réalisée à chaque fois au niveau de l'élément d'emballage supérieur (3) et de l'élément d'emballage inférieur (4) dans la région de la surface de scellage ou du joint de scellage, lesquelles découpes sont en coïncidence, etiii.) application d'une ligne de pliure ou de flexion (10), qui intercepte au moins une dite découpe (7, 8),la découpe (7) dans l'élément d'emballage supérieur (3) et la découpe coïncidente (8) dans l'élément d'emballage inférieur (4) étant réalisées de telle sorte que le point d'extrémité respectif (15, 16) des découpes présente une distance (M1) à la cavité (6) qui correspond au moins à la largeur (M2) du cordon de scellage (5).
- Procédé de fabrication d'un emballage (1) pour films contenant une dose unitaire de substance active selon la revendication 8, comprenant une étape supplémentaire iv.), au moins une découpe (7, 8) étant orientée à angle droit par rapport à l'arête extérieure la plus proche (6a) de la cavité (6).
- Utilisation d'un emballage (1) selon la revendication 1 pour recevoir des doses unitaires, tel que des films, des timbres ou des pansements, en particulier des pansements TTS, contenant une substance active.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13736824.7A EP2874908B1 (fr) | 2012-07-17 | 2013-07-02 | Emballage pour films contenant une dose unitaire d' une substance active ainsi que le procédé pour fabriquer cet emballage |
PL13736824T PL2874908T3 (pl) | 2012-07-17 | 2013-07-02 | Opakowanie na dozowane pojedynczo, zawierające substancję czynną listki oraz sposób wytwarzania tego opakowania |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP20120005237 EP2687458A1 (fr) | 2012-07-17 | 2012-07-17 | Emballage pour films contenant une dose unitaire d' une substance active. |
PCT/EP2013/063922 WO2014012787A1 (fr) | 2012-07-17 | 2013-07-02 | Emballage pour films unidose contenant une substance active et son procédé de fabrication |
EP13736824.7A EP2874908B1 (fr) | 2012-07-17 | 2013-07-02 | Emballage pour films contenant une dose unitaire d' une substance active ainsi que le procédé pour fabriquer cet emballage |
Publications (2)
Publication Number | Publication Date |
---|---|
EP2874908A1 EP2874908A1 (fr) | 2015-05-27 |
EP2874908B1 true EP2874908B1 (fr) | 2016-09-07 |
Family
ID=46640511
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP20120005237 Ceased EP2687458A1 (fr) | 2012-07-17 | 2012-07-17 | Emballage pour films contenant une dose unitaire d' une substance active. |
EP13736824.7A Active EP2874908B1 (fr) | 2012-07-17 | 2013-07-02 | Emballage pour films contenant une dose unitaire d' une substance active ainsi que le procédé pour fabriquer cet emballage |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP20120005237 Ceased EP2687458A1 (fr) | 2012-07-17 | 2012-07-17 | Emballage pour films contenant une dose unitaire d' une substance active. |
Country Status (13)
Country | Link |
---|---|
EP (2) | EP2687458A1 (fr) |
JP (1) | JP6422436B2 (fr) |
KR (1) | KR20150032702A (fr) |
CN (1) | CN104640781B (fr) |
AU (1) | AU2013292245B2 (fr) |
BR (1) | BR112015000813B1 (fr) |
CA (1) | CA2878330C (fr) |
ES (1) | ES2605432T3 (fr) |
HK (1) | HK1209713A1 (fr) |
MX (1) | MX351124B (fr) |
PL (1) | PL2874908T3 (fr) |
RU (1) | RU2633954C2 (fr) |
WO (1) | WO2014012787A1 (fr) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102009008217A1 (de) * | 2009-02-10 | 2010-08-19 | Lts Lohmann Therapie-Systeme Ag | Kindergesicherte, hochinerte Einzelverpackung |
DE102014104692A1 (de) * | 2014-04-02 | 2015-10-08 | Huhtamaki Flexible Packaging Germany, Zweigniederlassung Der Huhtamaki Flexible Packaging Germany Gmbh & Co. Kg | Verpackung |
JP2015217970A (ja) * | 2014-05-19 | 2015-12-07 | 大日本印刷株式会社 | 包装体 |
DE102021100782B3 (de) * | 2021-01-15 | 2022-07-14 | Lts Lohmann Therapie-Systeme Ag. | Otf-verbindung durch nähen |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3809220A (en) * | 1972-07-24 | 1974-05-07 | Becton Dickinson Co | Child safety package |
US5511665A (en) * | 1994-10-31 | 1996-04-30 | G. D. Searle & Co. | Child-resistant package |
US6199698B1 (en) * | 1999-12-03 | 2001-03-13 | Alusuisse Technology & Management, Ltd. | Pharmaceutical packaging with separation means |
CA2475376C (fr) * | 2002-02-08 | 2008-07-22 | The Procter & Gamble Company | Sachet a securite enfant |
DE102004047445B4 (de) | 2004-09-30 | 2007-05-31 | Lts Lohmann Therapie-Systeme Ag | Nichtwiederverschließbare Verpackung für gesundheitsgefährdende Erzeugnisse, Verwendung der Verpackung, sowie Verfahren zu deren Herstellung |
DE102004062864A1 (de) * | 2004-12-21 | 2006-06-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Folienbehälter |
US20060283747A1 (en) * | 2005-06-07 | 2006-12-21 | Gloria Lam Family Partnership, Llc | Condiment package with advertising for others |
DE102006041921A1 (de) | 2006-09-07 | 2008-03-27 | Lts Lohmann Therapie-Systeme Ag | Verpackung für wirkstoffhaltige Filme und Verfahren für deren Herstellung |
CA2657689A1 (fr) * | 2008-03-27 | 2009-09-27 | Bruce D. Detwiler | Emballages dechirables pour produit pharmaceutique, et methode |
CN101712384A (zh) * | 2008-09-30 | 2010-05-26 | 三洋电机株式会社 | 药品包装机 |
DE102009008217A1 (de) | 2009-02-10 | 2010-08-19 | Lts Lohmann Therapie-Systeme Ag | Kindergesicherte, hochinerte Einzelverpackung |
CN103339040B (zh) * | 2010-12-23 | 2016-01-13 | Lts勒曼治疗系统股份公司 | 高密封的单剂量包装件 |
-
2012
- 2012-07-17 EP EP20120005237 patent/EP2687458A1/fr not_active Ceased
-
2013
- 2013-07-02 CA CA2878330A patent/CA2878330C/fr active Active
- 2013-07-02 JP JP2015522029A patent/JP6422436B2/ja active Active
- 2013-07-02 KR KR20157000819A patent/KR20150032702A/ko active IP Right Grant
- 2013-07-02 AU AU2013292245A patent/AU2013292245B2/en not_active Ceased
- 2013-07-02 EP EP13736824.7A patent/EP2874908B1/fr active Active
- 2013-07-02 ES ES13736824.7T patent/ES2605432T3/es active Active
- 2013-07-02 WO PCT/EP2013/063922 patent/WO2014012787A1/fr active Application Filing
- 2013-07-02 BR BR112015000813-5A patent/BR112015000813B1/pt active IP Right Grant
- 2013-07-02 RU RU2015105053A patent/RU2633954C2/ru not_active IP Right Cessation
- 2013-07-02 MX MX2015000790A patent/MX351124B/es active IP Right Grant
- 2013-07-02 CN CN201380044805.XA patent/CN104640781B/zh active Active
- 2013-07-02 PL PL13736824T patent/PL2874908T3/pl unknown
-
2015
- 2015-10-28 HK HK15110625.5A patent/HK1209713A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
BR112015000813B1 (pt) | 2021-01-26 |
HK1209713A1 (en) | 2016-04-08 |
MX351124B (es) | 2017-10-02 |
EP2687458A1 (fr) | 2014-01-22 |
JP6422436B2 (ja) | 2018-11-14 |
AU2013292245A1 (en) | 2015-02-05 |
PL2874908T3 (pl) | 2017-05-31 |
CA2878330C (fr) | 2020-04-14 |
RU2015105053A (ru) | 2016-09-10 |
WO2014012787A1 (fr) | 2014-01-23 |
CN104640781A (zh) | 2015-05-20 |
CN104640781B (zh) | 2016-11-09 |
JP2015524290A (ja) | 2015-08-24 |
MX2015000790A (es) | 2015-05-07 |
BR112015000813A2 (pt) | 2017-06-27 |
AU2013292245B2 (en) | 2016-08-18 |
CA2878330A1 (fr) | 2014-01-23 |
KR20150032702A (ko) | 2015-03-27 |
ES2605432T3 (es) | 2017-03-14 |
EP2874908A1 (fr) | 2015-05-27 |
RU2633954C2 (ru) | 2017-10-19 |
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