EP2832733A4 - 4-alkanoylamino-3-pyrazolonderivat - Google Patents
4-alkanoylamino-3-pyrazolonderivatInfo
- Publication number
- EP2832733A4 EP2832733A4 EP13768519.4A EP13768519A EP2832733A4 EP 2832733 A4 EP2832733 A4 EP 2832733A4 EP 13768519 A EP13768519 A EP 13768519A EP 2832733 A4 EP2832733 A4 EP 2832733A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- alkanoylamino
- pyrazolone derivative
- pyrazolone
- derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/01—Saturated compounds having only one carboxyl group and containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2012079858 | 2012-03-30 | ||
PCT/JP2013/059656 WO2013147215A1 (ja) | 2012-03-30 | 2013-03-29 | 4-アルカノイルアミノ-3-ピラゾロン誘導体 |
Publications (3)
Publication Number | Publication Date |
---|---|
EP2832733A1 EP2832733A1 (de) | 2015-02-04 |
EP2832733A4 true EP2832733A4 (de) | 2015-09-30 |
EP2832733B1 EP2832733B1 (de) | 2018-08-29 |
Family
ID=49260456
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP13768519.4A Not-in-force EP2832733B1 (de) | 2012-03-30 | 2013-03-29 | 4-alkanoylamino-3-pyrazolonderivat |
Country Status (11)
Country | Link |
---|---|
US (1) | US9212170B2 (de) |
EP (1) | EP2832733B1 (de) |
JP (1) | JP6126078B2 (de) |
KR (1) | KR20140138208A (de) |
CN (1) | CN104321318A (de) |
CA (1) | CA2869130A1 (de) |
ES (1) | ES2699404T3 (de) |
HK (1) | HK1204621A1 (de) |
IN (1) | IN2014MN01988A (de) |
TW (1) | TW201400470A (de) |
WO (1) | WO2013147215A1 (de) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2017114765A (ja) * | 2014-04-25 | 2017-06-29 | 大正製薬株式会社 | トリアゾリルで置換されたヘテロアリール化合物 |
CN112375072B (zh) * | 2020-09-28 | 2021-05-28 | 上海长征富民金山制药有限公司 | 吡唑啉酮衍生物、注射剂及其用途 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102008020113A1 (de) * | 2008-04-23 | 2009-10-29 | Bayer Schering Pharma Aktiengesellschaft | Substituierte Dihydropyrazolone und ihre Verwendung |
DE102005019712A1 (de) * | 2005-04-28 | 2006-11-09 | Bayer Healthcare Ag | Dipyridyl-dihydropyrazolone und ihre Verwendung |
DE102006050516A1 (de) * | 2006-10-26 | 2008-04-30 | Bayer Healthcare Ag | Substituierte Dihydropyrazolone und ihre Verwendung |
DE102006050515A1 (de) * | 2006-10-26 | 2008-04-30 | Bayer Healthcare Ag | Substituierte Dipyridiyl-dihydropyrazolone und ihre Verwendung |
DE102007044032A1 (de) | 2007-09-14 | 2009-03-19 | Bayer Healthcare Ag | Substituierte heterocyclische Verbindungen und ihre Verwendung |
US20110112103A1 (en) | 2008-04-22 | 2011-05-12 | Daiichi Sankyo Company, Limited | 5-hydroxypyrimidine-4-carboxamide compound |
MY179093A (en) * | 2008-12-29 | 2020-10-27 | Sanofi Sa | Derivatives of 2-pyridin-2-yl-pyrazol-3(2h)-one, preparation and therapeutic use thereof as hif activators |
PL2382215T3 (pl) * | 2008-12-29 | 2015-01-30 | Sanofi Sa | Pochodne 2-pirydyny-2-ylo-pirazol-3(2H)-onu, ich wytwarzanie i zastosowanie terapeutyczne |
JP2011105708A (ja) * | 2009-10-21 | 2011-06-02 | Daiichi Sankyo Co Ltd | 5−ヒドロキシピリミジン−4−カルボキサミド化合物を含有する医薬組成物 |
JP2011088840A (ja) * | 2009-10-21 | 2011-05-06 | Daiichi Sankyo Co Ltd | 5−ヒドロキシピリミジン−4−カルボキサミド化合物を含有する医薬組成物 |
-
2013
- 2013-03-29 EP EP13768519.4A patent/EP2832733B1/de not_active Not-in-force
- 2013-03-29 CN CN201380028513.7A patent/CN104321318A/zh active Pending
- 2013-03-29 IN IN1988MUN2014 patent/IN2014MN01988A/en unknown
- 2013-03-29 CA CA2869130A patent/CA2869130A1/en not_active Abandoned
- 2013-03-29 JP JP2014508119A patent/JP6126078B2/ja active Active
- 2013-03-29 TW TW102111318A patent/TW201400470A/zh unknown
- 2013-03-29 ES ES13768519T patent/ES2699404T3/es active Active
- 2013-03-29 KR KR1020147026675A patent/KR20140138208A/ko not_active Application Discontinuation
- 2013-03-29 WO PCT/JP2013/059656 patent/WO2013147215A1/ja active Application Filing
-
2014
- 2014-09-24 US US14/495,052 patent/US9212170B2/en not_active Expired - Fee Related
-
2015
- 2015-06-03 HK HK15105296.3A patent/HK1204621A1/xx unknown
Non-Patent Citations (2)
Title |
---|
No further relevant documents disclosed * |
See also references of WO2013147215A1 * |
Also Published As
Publication number | Publication date |
---|---|
ES2699404T3 (es) | 2019-02-11 |
KR20140138208A (ko) | 2014-12-03 |
US9212170B2 (en) | 2015-12-15 |
CA2869130A1 (en) | 2013-10-03 |
WO2013147215A1 (ja) | 2013-10-03 |
EP2832733A1 (de) | 2015-02-04 |
JPWO2013147215A1 (ja) | 2015-12-14 |
HK1204621A1 (en) | 2015-11-27 |
IN2014MN01988A (de) | 2015-07-10 |
US20150011552A1 (en) | 2015-01-08 |
JP6126078B2 (ja) | 2017-05-10 |
EP2832733B1 (de) | 2018-08-29 |
CN104321318A (zh) | 2015-01-28 |
TW201400470A (zh) | 2014-01-01 |
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