EP2743248A4 - Procédé d'obtention d'extrait d'hydroxytyrosol, mélange d'extrait d'hydroxytyrosol et de 3,4-dihydroxyphénylglycol, et extrait d'acétate d'hydroxityrosile, à partir de sous-produits de l'olive, et sa purification - Google Patents

Procédé d'obtention d'extrait d'hydroxytyrosol, mélange d'extrait d'hydroxytyrosol et de 3,4-dihydroxyphénylglycol, et extrait d'acétate d'hydroxityrosile, à partir de sous-produits de l'olive, et sa purification

Info

Publication number
EP2743248A4
EP2743248A4 EP12811374.3A EP12811374A EP2743248A4 EP 2743248 A4 EP2743248 A4 EP 2743248A4 EP 12811374 A EP12811374 A EP 12811374A EP 2743248 A4 EP2743248 A4 EP 2743248A4
Authority
EP
European Patent Office
Prior art keywords
extract
hydroxytyrosol
dihydroxyphenylglycol
purification
products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP12811374.3A
Other languages
German (de)
English (en)
Other versions
EP2743248A1 (fr
Inventor
Guzmán Juan Fernández-Bolaños
Gutiérrez Guillermo Rodríguez
Muñoz Antonio Lama
Rubio Fátima Senent
Guzmán José María Fernández-Bolaños
Castilla Inés Maya
López Óscar López
Castro Azucena Marset
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Consejo Superior de Investigaciones Cientificas CSIC
Universidad de Sevilla
Original Assignee
Consejo Superior de Investigaciones Cientificas CSIC
Universidad de Sevilla
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Consejo Superior de Investigaciones Cientificas CSIC, Universidad de Sevilla filed Critical Consejo Superior de Investigaciones Cientificas CSIC
Publication of EP2743248A1 publication Critical patent/EP2743248A1/fr
Publication of EP2743248A4 publication Critical patent/EP2743248A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/68—Purification; separation; Use of additives, e.g. for stabilisation
    • C07C37/70—Purification; separation; Use of additives, e.g. for stabilisation by physical treatment
    • C07C37/82—Purification; separation; Use of additives, e.g. for stabilisation by physical treatment by solid-liquid treatment; by chemisorption
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10—General cosmetic use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Birds (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP12811374.3A 2011-07-08 2012-07-03 Procédé d'obtention d'extrait d'hydroxytyrosol, mélange d'extrait d'hydroxytyrosol et de 3,4-dihydroxyphénylglycol, et extrait d'acétate d'hydroxityrosile, à partir de sous-produits de l'olive, et sa purification Withdrawn EP2743248A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES201131161A ES2395317B1 (es) 2011-07-08 2011-07-08 Procedimiento para la obtención de extracto de hidroxitirosol, extracto mezcla de hidroxitirosol y 3,4-dihidroxifenilglicol, y extracto de acetato de hidroxitirosilo, a partir de subproductos del olivo y su purificación.
PCT/ES2012/070491 WO2013007850A1 (fr) 2011-07-08 2012-07-03 Procédé d'obtention d'extrait d'hydroxytyrosol, mélange d'extrait d'hydroxytyrosol et de 3,4-dihydroxyphénylglycol, et extrait d'acétate d'hydroxityrosile, à partir de sous-produits de l'olive, et sa purification

Publications (2)

Publication Number Publication Date
EP2743248A1 EP2743248A1 (fr) 2014-06-18
EP2743248A4 true EP2743248A4 (fr) 2015-02-25

Family

ID=47505550

Family Applications (1)

Application Number Title Priority Date Filing Date
EP12811374.3A Withdrawn EP2743248A4 (fr) 2011-07-08 2012-07-03 Procédé d'obtention d'extrait d'hydroxytyrosol, mélange d'extrait d'hydroxytyrosol et de 3,4-dihydroxyphénylglycol, et extrait d'acétate d'hydroxityrosile, à partir de sous-produits de l'olive, et sa purification

Country Status (3)

Country Link
EP (1) EP2743248A4 (fr)
ES (1) ES2395317B1 (fr)
WO (1) WO2013007850A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2813221A1 (fr) * 2013-06-13 2014-12-17 Natac Biotech, S.L. Combinaison de triterpènes pentacycliques et d'hydroxytyrosol et ses dérivés
ES2539637B1 (es) * 2013-09-24 2016-02-05 Universidad De Sevilla Nuevos antiiflamatorios basados en polifenoles del olivo
CN104402680B (zh) * 2014-12-12 2016-05-11 黑龙江八一农垦大学 一种通过离子交换树脂转化橄榄苦苷制备羟基酪醇的方法
ES2881826B2 (es) * 2020-05-28 2022-09-14 Consejo Superior Investigacion Procedimiento de obtencion de 3,4-dihidroxifenilglicol (dhfg)
CL2021001885A1 (es) 2021-07-15 2021-12-17 American Bioprocess Ltda Proceso para la obtención de extractos concentrados en hidroxitirosol (ht)
CN113860999A (zh) * 2021-10-12 2021-12-31 东莞职业技术学院 一种利用油橄榄叶制备羟基酪醇的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008090460A1 (fr) * 2007-01-26 2008-07-31 Probelte Pharma, S.A. Procédé et appareil de production d'extraits contenant de l'hydroxytyrosol à partir d'olives et de résidus solides d'extraction d'huile d'olive

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2186467B1 (es) 2000-03-03 2004-09-16 Consejo Superior De Investigaciones Cientificas Obtencion de sustancias antioxidantes a partir de soluciones del proceso de elaboracion de aceitunas de mesa.
ES2170006B1 (es) 2000-08-11 2003-11-01 Consejo Superior Investigacion Sintesis enzimatica del antioxidante hidroxitirosol.
AU8858001A (en) 2000-09-01 2002-03-13 Creagri Inc Method of obtaining a hydroxytyrosol-rich composition from vegetation water
DE60229501D1 (de) 2001-02-15 2008-12-04 Consejo Superior Investigacion Verfahren zur gewinnung von gereinigtem hydroxytyrosol aus von dem olivenbaum erhaltenen produkten und nebenprodukten
ES2246603B1 (es) 2002-07-03 2007-06-16 Consejo Sup. De Investig. Cientificas Procedimiento para la preparacion de esteres de hidroxitirosol, esteres obtenidos y utilizacion.
ITMI20041627A1 (it) 2004-08-06 2004-11-06 Lachifarma S R L Lab Chimi Co Processo per il recupero di tirosolo idrossitirosolo e altri componenti fenolici da acque di vegetazione e metodo di ossidazione catalitica di tirosolo a idrossitirosolo
WO2007009590A1 (fr) 2005-07-18 2007-01-25 Dsm Ip Assets B.V. Procede de preparation de composes phenoliques
WO2007074490A1 (fr) 2005-12-29 2007-07-05 Universita' Degli Studi Di Napoli Federico Ii Procédé de production de triacétylhydroxytyrosol à partir de margines de moulins à huile d'olive en vue de son utilisation comme antioxydant stabilisé
ES2311401B1 (es) 2007-05-22 2009-12-22 Ges-Biolives, S.L. Procedimiento para la obtencion de extractos con alto contenido en hidroxitirosol a partir de productos derivados de la oliva.
ES2341526B1 (es) * 2008-12-19 2011-06-08 Consejo Superior De Investigaciones Cientificas (Csic) Procedimiento de purificacion de 3,4-dihidroxifenilglicol (dhfg) a partir de productos vegetales.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008090460A1 (fr) * 2007-01-26 2008-07-31 Probelte Pharma, S.A. Procédé et appareil de production d'extraits contenant de l'hydroxytyrosol à partir d'olives et de résidus solides d'extraction d'huile d'olive

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MEDINA ET AL.: "Comparison of the Concentrations of Phenolic Compounds in Olive Oils and Other Plant Oils: Correlation with Antimicrobial activity", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, vol. 54, 13 June 2006 (2006-06-13), pages 4954 - 4961, XP002722174 *
ROMERO ET AL.: "In Vitro Activity of Olive Oil Polyphenols agains Heliobacter pylori", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, vol. 55, 17 January 2007 (2007-01-17), pages 680 - 686, XP002722173 *
See also references of WO2013007850A1 *

Also Published As

Publication number Publication date
WO2013007850A1 (fr) 2013-01-17
ES2395317B1 (es) 2014-04-16
ES2395317A1 (es) 2013-02-11
EP2743248A1 (fr) 2014-06-18

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