HUE054747T2 - Eljárás közvetlenül tablettázható delta-mannit elõállítására - Google Patents

Eljárás közvetlenül tablettázható delta-mannit elõállítására

Info

Publication number
HUE054747T2
HUE054747T2 HUE16001371A HUE16001371A HUE054747T2 HU E054747 T2 HUE054747 T2 HU E054747T2 HU E16001371 A HUE16001371 A HU E16001371A HU E16001371 A HUE16001371 A HU E16001371A HU E054747 T2 HUE054747 T2 HU E054747T2
Authority
HU
Hungary
Prior art keywords
preparation
directly tablettable
mannitol
tablettable mannitol
directly
Prior art date
Application number
HUE16001371A
Other languages
English (en)
Inventor
Martin Erdmann
Walter Hamm
Eugen Schwarz
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of HUE054747T2 publication Critical patent/HUE054747T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/74Separation; Purification; Use of additives, e.g. for stabilisation
    • C07C29/76Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment
    • C07C29/78Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment by condensation or crystallisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/74Separation; Purification; Use of additives, e.g. for stabilisation
    • C07C29/76Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
HUE16001371A 2010-12-17 2011-11-17 Eljárás közvetlenül tablettázható delta-mannit elõállítására HUE054747T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP10015770 2010-12-17

Publications (1)

Publication Number Publication Date
HUE054747T2 true HUE054747T2 (hu) 2021-09-28

Family

ID=44993528

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE16001371A HUE054747T2 (hu) 2010-12-17 2011-11-17 Eljárás közvetlenül tablettázható delta-mannit elõállítására

Country Status (7)

Country Link
US (1) US8716536B2 (hu)
EP (2) EP2651397A2 (hu)
JP (2) JP2014501226A (hu)
CN (2) CN106727355A (hu)
HU (1) HUE054747T2 (hu)
PL (1) PL3093011T3 (hu)
WO (1) WO2012079671A2 (hu)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2994569B1 (fr) * 2012-08-17 2016-11-04 Roquette Freres Procede de fabrication de compositions riches en cristaux de mannitol sous forme delta, compositions et cristaux obtenus ainsi que leurs utilisations

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3145146A (en) 1961-10-31 1964-08-18 Warner Lambert Pharmaceutical Modified mannitol for pharmaceutical tablets
CN1221398A (zh) 1996-04-16 1999-06-30 拜尔公司 甘露糖醇及其制备
DE19615418A1 (de) * 1996-04-22 1997-10-23 Merck Patent Gmbh Polyol-Zusammensetzung
JP2001519378A (ja) * 1997-10-15 2001-10-23 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング 直接圧縮可能な錠剤化助剤の製造
DE19927537A1 (de) 1999-06-16 2000-12-21 Merck Patent Gmbh Sprühtrocknungsanlage und Verfahren zu ihrer Verwendung
DE10161402A1 (de) 2001-12-13 2003-06-18 Merck Patent Gmbh Verfahren zur Herstellung von direkt tablettierbarem beta-Mannit
DE10240778A1 (de) * 2002-08-30 2004-03-11 Merck Patent Gmbh Verfahren zur Herstellung von direkt tablettierbarem a-Mannit
EP1623153A1 (de) 2003-05-15 2006-02-08 Lucea AG Lichtquelle
EP1940358A2 (en) * 2005-09-30 2008-07-09 SmithKline Beecham Corporation Pharmaceutical compositions
CA2634232C (en) * 2005-12-28 2013-08-20 Takeda Pharmaceutical Company Limited Method of producing solid preparation disintegrating in the oral cavity
WO2008147811A1 (en) * 2007-05-22 2008-12-04 Ssci, Inc. Preparation of mannitol modification iii
CN102170912A (zh) * 2008-09-30 2011-08-31 大洋药品工业株式会社 压缩成型制剂及其制造方法

Also Published As

Publication number Publication date
WO2012079671A3 (de) 2012-08-30
CN103429229A (zh) 2013-12-04
US20130261346A1 (en) 2013-10-03
CN106727355A (zh) 2017-05-31
PL3093011T3 (pl) 2021-09-06
JP2014501226A (ja) 2014-01-20
EP3093011B1 (de) 2021-03-24
EP2651397A2 (de) 2013-10-23
US8716536B2 (en) 2014-05-06
EP3093011A1 (de) 2016-11-16
WO2012079671A2 (de) 2012-06-21
JP2017036280A (ja) 2017-02-16
JP6419759B2 (ja) 2018-11-07

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