EP2706955A1 - Endovaskularprothese - Google Patents

Endovaskularprothese

Info

Publication number
EP2706955A1
EP2706955A1 EP12726818.3A EP12726818A EP2706955A1 EP 2706955 A1 EP2706955 A1 EP 2706955A1 EP 12726818 A EP12726818 A EP 12726818A EP 2706955 A1 EP2706955 A1 EP 2706955A1
Authority
EP
European Patent Office
Prior art keywords
stent
endoprosthesis according
main member
distal portion
endoprosthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP12726818.3A
Other languages
English (en)
French (fr)
Inventor
George L. De Goicoechea
Juan Carlos Parodi
Guro BJØRNSTAD
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
St George Medical Inc
Original Assignee
St George Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by St George Medical Inc filed Critical St George Medical Inc
Publication of EP2706955A1 publication Critical patent/EP2706955A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2/07Stent-grafts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/39Markers, e.g. radio-opaque or breast lesions markers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/856Single tubular stent with a side portal passage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/89Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure the wire-like elements comprising two or more adjacent rings flexibly connected by separate members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2002/065Y-shaped blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2002/065Y-shaped blood vessels
    • A61F2002/067Y-shaped blood vessels modular

Definitions

  • the invention relates to a stent or more generally to a device intended to be introduced into a vessel whose walls are aneurysmal so that the blood stops passing in said vessel proper and can circulate in the stent.
  • the invention relates more particularly but in a nonlimiting manner to a stent for a patient suffering from aneurism of the abdominal aorta.
  • Aneurysm of the abdominal aorta is a serious pathology that usually results in permanent and localized dilatation of the abdominal aortic aorta.
  • This dilation may be more than 50% greater than the nominal diameter generally accompanied by a loss of parallelism of its edges in the form of bag (saccular aneurysm) or spindle (fusiform aneurysm).
  • bag saccular aneurysm
  • spindle fusiform aneurysm
  • the progressive growth of this aneurysm is inevitable and difficult to predict.
  • the placement of a femoral stent to be attached to the arterial walls upstream and downstream of the aneurysm using stents (metal or polymeric structures) is currently one of the main techniques for the treatment of a stent.
  • Aneurysm of the abdominal aorta a technique considered less invasive than surgery.
  • stents consist mainly of a generally metallic tubular or bifurcated structure whose metal mesh (stent) is covered with a thin synthetic membrane.
  • This stent is introduced into the femoral artery at the fold of the groin. It is generally folded into a tube or sheath - sometimes also called introducer - which progresses from the inside of the vessel to the level of the aneurysm where it is deployed.
  • the metal structure even complementary attachment devices to the wall of the aorta normally prevent any migration of the stent and prevent the blood from circulating in the cavity of the aneurysm or aneurysm sac.
  • the deployment of the stent may be automatic during removal of the sheath (spring effect of the metal mesh - stent) or by means of the balloon also introduced into said sheath which is inflated on demand to expand the metal mesh of one stent.
  • This last technique is particularly effective especially in case of loss of parallelism of the edges of the aortic aorta.
  • current stents do not however ensure a good level of tightness at the anchor point of the stent between the outer wall of the stent and the inner wall of the abdominal aorta.
  • the evolution of the pathology in particular can indeed create endoleaks synonymous that blood rushes over time into the aneurysmal sac leading to certain and severe complications.
  • the known stents give little guidance to the practitioner during their installation or the patient's follow-up regarding his positioning within the pathological vessel. This often gives an additional difficulty for the practitioner in performing his therapeutic gesture or in accompanying a patient.
  • known stents generally consist of an integral stent (metal mesh) covered with a membrane. This is especially the case of stents whose installation is performed using a sheath binding said stent and whose removal causes the automatic expansion of the stent so that it can take shape within the vessel.
  • This structure generates a significant cost of manufacture and a certain rigidity which can be detrimental according to the configuration of the aneurysm that one seeks to cure.
  • the invention makes it possible to meet all the disadvantages raised by the known solutions.
  • the invention mainly consists in providing extensible means of textile or polymer type positioned in the form of an outer ring at the upper distal portion of the tubular member of the stent so that said means prevents any endoleak.
  • said extensible means adhere to the inner wall of the aorta after dilation of an upper stent upstream of the aneurysmal sac and downstream of the renal arteries. Thanks to the invention, it is possible to eliminate any therapeutic complication.
  • a stent is provided first comprising a substantially tubular main member whose upper distal portion cooperates with a stent.
  • said stent comprises extensible textile means covering the lower portion of said stent and cooperating with the upper distal portion of said member.
  • the tubular member may consist of a woven polyester.
  • the stent may be further extensible, non-retractable consisting of a metal mesh based on cobalt chromium and nitinol.
  • said stent may consist of a stainless steel wire mesh.
  • the extensible means may advantageously consist of a knitted material comprising an elastic synthetic fiber.
  • the main member of an endoprosthesis may further comprise a substantially tubular extension or frustoconical section cooperating with the main member.
  • the main limb may consist of an "inverted Y" whose bifurcation intervenes in its lower part.
  • the extensible means section of such a stent may preferably be substantially frustoconical.
  • an endoprosthesis according to the invention may comprise radiopaque means.
  • the latter may consist of a thread encircling the upper part of the extensible means or a wire cooperating with the main member over the entire length of the latter.
  • the lower portion of the primary limb may include a stent.
  • the tubular main member may be surrounded by a plurality of son made of a shape memory material whose section is substantially smaller than that of the member.
  • the lower distal portion of the tubular main member or an extension which may advantageously comprise son made of a shape memory material, undulating and surrounding said lower part of the member or said extension.
  • said stent may advantageously comprise one or more openings facilitating lateral blood flow.
  • FIG. 1 shows a partial view of the vascular system of a healthy subject or a patient with aneurysm of the abdominal aorta;
  • FIG. 2 shows a process of angioplasty using a known stent
  • FIG. 3 depicts a stent conforming to
  • FIG. 4 depicts an advantageous embodiment of a stent cooperating with the upper distal portion of the main limb of a stent according to the invention
  • FIGS. 5 and 6 respectively show two advantageous embodiments incorporating a stent such as that described with reference to FIG. 4.
  • Figure 1 shows a partial view of a vascular system of a healthy subject 1 and that of a patient with aneurysm of the abdominal aorta (partial view Vb on the right of Figure 1).
  • the aorta of a subject originates at the level of the heart 2 and is prolonged by the thoracic aorta 3 then by the so-called abdominal aorta 6 downstream of the renal arteries 5a and 5b which serve respectively the kidneys 4a and 4b.
  • the abdominal aortic aorta of a healthy subject has substantially parallel walls. It further has a 6x bifurcation in its lower part to give rise to the primitive iliac arteries 7a and 7b.
  • the sub-renal abdominal aorta 6 can present a pathology known as aneurysm. Said abdominal aorta is deformed to the point of forming - downstream of the renal arteries and upstream of the primary iliac arteries - an aneurysmal sac whose growth is inevitable and unpredictable.
  • One known therapy is to perform angioplasty.
  • a stent is then positioned within the aortic pathology so that the blood stops circulating in the aneurysmal sac but circulates through said stent.
  • FIG. 2 depicts an angioplasty process for an abdominal aorta.
  • a sheath 13 is introduced into a femoral artery at the crease of the groin of a patient.
  • This sheath 13 progresses within a primitive iliac artery 7a and then through the aneurysm sac 6a of the abdominal aorta 6 upstream of the renal arteries 5a and 5b.
  • This sheath 13 comprises within it an endoprosthesis 10 which, according to the example described with reference to FIG. 2, unfolds automatically during removal of the sheath under the spring effect of an internal stent 11 with a stent covered with a membrane 12 and kept compressed by the sheath.
  • Such a stent results in a metal mesh generally made from an alloy of cobalt and chromium. According to a known technique, it is thus possible to deploy a stent whose shape is substantially that of an inverted "Y" so that blood from the thoracic aorta is conveyed through the stent to the renal arteries 5a, 5b then to the primitive iliac arteries 7a, 7b. The blood flows from the thoracic aorta to the renal arteries through the upper distal portion 10h of the stent, where the stent is not covered by the membrane 12 of the stent. main member of the stent.
  • this membrane usually woven based on a polyester - covers said stent along the entire length of the main member 12 with the exception of said upper distal portion 10h of the stent.
  • the blood can therefore flow freely through the metal mesh of the stent 11 at the upper distal portion of the stent 10h.
  • the membrane of the main limb 12 prevents any blood flow within the aneurysm sac.
  • the shape of the main member bifurcated substantially in "Y" inverted allows to provide two lower distal portions respectively adjusted to the anatomy of the patient's primary iliac arteries.
  • a stent comprising a main member based on a polyester and having a stent cooperating essentially with said main member at the upper distal portion of said member.
  • the primary limb of such a stent may describe an inverted "Y" to ultimately route blood from the thoracic aorta to the primary iliac arteries.
  • the stent differs from the previous one in that the deployment of the limb and the stent is not done automatically when removing the constraining sheath 1 'endoprosthesis. Said deployment is done by means of the use of a balloon inside the stent.
  • Controlled inflation of the latter makes it possible to remove the mesh from the stent so that it deforms sufficiently to adhere upstream of the renal arteries to the healthy walls of the pathological aorta.
  • a stent will be preferred in particular in case of loss of parallelism of the walls located upstream of the aneurysmal sac or even in the case where the said aorta is not regular.
  • the use of a balloon expandable stent reduces the range of prostheses required to meet the majority of patients.
  • the balloon makes it possible to control the dilation of the stent and promotes the application of a stent to a large number of cases.
  • an expandable stent automatically generally requires a wider range of stents to provide different ranges of dilation and stent opening power to provide, in particular, anchorage of the stent to the pathological artery wall.
  • a stent is positioned such that the stent upstream of the limb 12 circulates blood from the thoracic aorta to the renal arteries.
  • the main member prevents any blood flow into the aneurysm sac.
  • the invention makes it possible to meet the disadvantages of known stents.
  • the stent according to the invention will preferably be described in connection with an aneurysm of the abdominal aorta.
  • the main member thereof could thus be only and substantially tubular without having a bifurcation (s).
  • FIG. 3 makes it possible to describe a preferred embodiment of a stent according to the invention and particularly adapted to the pathology of the aneurysm of the abdominal aorta.
  • Such a stent 10 according to the invention comprises a substantially tubular main member 12 whose upper distal portion cooperates with a stent 11a.
  • said stent is extensible by means of an unrepresented internal balloon. It has a metal mesh (preferably based on cobalt, chromium, nitinol or even stainless steel alloys). The mesh is made so that during inflation of the balloon, the stent expands without retracting.
  • a stent may be in accordance with that described in US Pat. No. 7,357,813.
  • the main member 12 is preferably constituted by a woven fabric for example a polyester. Its structure is therefore little or not extensible and offers a good level of tightness. According to a particular embodiment, said member may be corrugated by the use of one or more polyester threads 12f which surround said member 12. The section of said polyester threads 12f is substantially smaller than that of the member 12.
  • the use of these son allows the member 12 to be provided with a "shape memory" and thus recover its tubular shape during the deployment of 1 stent. Any other shape memory material (for example a polymer tolerated by the living) could alternatively be used. This technique facilitates the first passage of blood through said limb just after the stent has been laid.
  • a secondary stent 11b can be provided preferably in the lower portion 10b of the main member.
  • this stent is self-expanding and is preferably made from a yarn (or a plurality of yarns) made from a memory material. of form, nitinol for example, wire (s) cooperating with the lower part of the main member.
  • this stent 11b can be balloon expandable as is the stent 11a. The height of the stent 11b may be less than that of the stent 11a.
  • the stent IIa is used not only to attach the stent to the wall of the aorta upstream of the renal arteries but the height of the latter must be sufficient to allow free blood circulation through the mesh of the stent to irrigate said renal arteries.
  • the height of the stent may be between three and six centimeters.
  • the height of the stent IIa can be reduced.
  • the stent is intended for angioplasty. abdominal aorta.
  • the main member 12 therefore has a bifurcation and two lower distal parts. These distal portions 20 and 21 are intended to cooperate with the primary iliac arteries of the patient. Traditionally, the distal portion corresponding to the iliac artery through which the sheath with the stent has been introduced may be longer than the second. This inverted "Y" structure of the main limb 12 depends on the angioplasty to be performed.
  • the main member can be simply tubular in other examples of applications.
  • the secondary stent 11b is preferably positioned at the bifurcation. According to the invention, other secondary stents could be provided to cooperate with the lower distal parts of the limb 12.
  • any stent according to the invention comprises extensible textile means 14 covering the lower part of the stent 11a and cooperating with the upper distal portion of the main member 12.
  • Such means may consist of an extensible ring made from a knitted material comprising an elastic synthetic fiber of elastane type for example. Other fibers could be used. It suffices that the ring can be deformed sufficiently to accompany the dilation of the stent IIa without retracting in height.
  • These means 14 provide, by virtue of their texture, increased sealing at the anchoring point of the stent or more exactly at the point of contact of said means 14 and of the internal wall of the abdominal aorta downstream of the stents. renal arteries and upstream of the aneurysmal sac. In addition, the material adheres naturally to the wall of the artery so that inadvertent migration of the stent is prevented.
  • said means 14 are fixed 15 - for example sewn - to the metal mesh of the stent 11a to ensure good performance.
  • the means 14 are further fixed 16 to cooperate with the upper distal portion of the main member 12.
  • the main member 12 may take an average length - determined empirically or statistically - of the order of 8 cm.
  • the height of the stent IIa can be about 3cm to allow a good anchorage and let blood circulate from the aorta to the renal arteries.
  • the height of the sealing ring 14 may preferably be from 10 to 15 mm.
  • the section of the main member 12 - in particular the upper distal portion cooperating with the means 14 - is determined to be in line with a majority of subjects.
  • the invention advantageously provides that the section of the stents can change from 22 to 28mm for a first stent and 28 to 34mm for a second.
  • the section of the main member is substantially 22mm and 24mm for the second arrangement. Other variants could be further considered.
  • the invention provides one or more substantially tubular extensions - made from a material similar to that of the main member for cooperating with said distal portions of the main limb.
  • Figure 3 describes two types of extensions 22 and 23.
  • the first type of extension 23 is substantially tubular whose sections of the distal portions 23t, 23b are substantially identical.
  • Such an extension may take a length of several centimeters in order to adapt to the anatomical constraints of the patient. Statistically, a length of 5cm seems to be advantageously chosen.
  • Such an extension may have a section of the same order as the section of the distal portion 21b of the main member that is to be elongated. Thus a section of the order of 10 mm can be advantageously chosen.
  • Figure 3 describes a variant in which the extension 22 is frustoconical section.
  • the invention provides a somewhat flared extension, 10 to 12mm for a first distal portion 22t and 16 to 22mm for the second 22b.
  • said extension fits within the distal portion of the member to be lengthened to a depth of the order of 30mm.
  • Other configurations and arrangements could however be imagined according to the invention.
  • the lower distal portion (s) 20, 21 of the main limb and / or the extensions 22 or 23 may comprise one or more son of undulating nitinol 25 and surrounding said lower limb 12 and extensions.
  • nitinol wires are sewn on the inner or outer walls of the elements (main member and / or extensions).
  • the wires are sewn on the outer wall of the element. This arrangement prevents the appearance possible thrombi resulting from prolonged blood contact, whose flow may be low, with said son 25.
  • Yarns made from polymers or any other shape memory material could be used in addition or alternatively nitinol.
  • the use of the means 25 ensures that the lower part of the stent and possibly extensions can not pinch or hinder the passage of blood to the first blood passage.
  • the straight or frustoconical section of the extensions makes it possible to adapt to the patient's anatomy.
  • the extensible material of the means 14 to ensure a good seal must not interfere with the blood supply including renal arteries in the case of a suprarenal stent as described in connection with Figure 3.
  • the means 14 may comprise a radiopaque wire 17 (gold or platinum-based for example) encircling the upper part of said means 14.
  • the main member 12 of an endoprosthesis according to the invention may comprise a radiopaque wire 18 cooperating with the main member over the entire length of this latest.
  • radio-opaque means although structurally different than wires but capable of performing the same functions as the wires 17 and 18 could be exploited.
  • the use of radio-opaque means (17 or 18) thus makes it possible to detect any bad position of the means 14 but also any unintended pinching or twisting of the main member.
  • Such means could further cooperate with the extensions as described above.
  • a practitioner operating during the angioplasty of the radiological means has a valuable help to verify the relevance of his therapeutic gesture.
  • Figures 4, 5 and 6 describe a stent preferably adapted to cooperate with the upper distal portion of a main member of an endoprosthesis according to the invention.
  • the stent 11a illustrated in Figure 4 has a particularly advantageous configuration especially when said stent is to be deployed at a junction between the main vessel (undergoing angioplasty) and one or more secondary vessels.
  • the stent 11a has three contiguous cylindrical portions respectively: 10x for the proximal (or lower) part, 10y for the central part and 10z for the distal (or upper) part.
  • such a stent may advantageously be used as an anchoring stent for a suprarenal stent treating an abdominal aortic aneurysm such as the stent previously described in connection with Figure 3.
  • the stent of such a stent may be deployed (automatically or via a balloon) at the junction of the renal arteries to the abdominal aorta.
  • the central portion 10y of the stent 11a is arranged to present one or more openings to facilitate a lateral flow of blood (for example to the arteries renal).
  • the mesh of the stent is thus "lightened” in its central part 10y with regard to the proximal portions 10x and distal 10z.
  • said mesh 10y remains advantageously robust - despite said openings - to ensure a reliable connection between the distal portions 10z and proximal 10x.
  • the distal portion 10z of the stent may advantageously be arranged to develop a radial force greater than that developed by the other two portions 10x and 10y in order to maximize a "formwork" function or to optimize the anchoring of the prosthesis during the deployment of the stent (automatic or assisted by balloon).
  • FIG. 5 depicts a partial enlargement of a suprarenal stent similar to that previously described in connection with FIG. 3 and whose stent 11a is in accordance therewith with reference to FIG. 4.
  • the height stent 11a is advantageously chosen to be substantially equal to 4.5 centimeters. Generally said height can vary between three and six centimeters for the stent of such a stent.
  • the union 10O of the distal portions 10O and central 10y of the stent 11a is covered neither by the main member 12 nor by the sealing means 14.
  • the lower cylindrical portion 10x is in turn covered by the means 14 ensuring good seal against the wall of the aorta located below the renal arteries.
  • the lower part 10x of said stent 11a thus appears in dashed transparency in FIG. 5.
  • the arrangement of the central part 10y of the stent 11a facilitates blood circulation at the junction of the renal arteries with the abdominal aorta. This advantageous arrangement prevents any obstruction of the blood flow circulating in the renal arteries. A risk of micro-clot formation to the kidneys is thereby reduced.
  • the upper (or distal) part 10 of the stent may advantageously be arranged to develop a radial force greater than that developed by the two other portions 10x and 10y and to optimize the anchoring of the prosthesis during deployment of the stent (automatic or assisted by ballooning). ).
  • FIG. 6 depicts a partial view of the distal or superior portion of a second suprarenal stent according to the invention and incorporating a stent as described previously in FIG. 4.
  • the main member 12 of the stent extends (opposite the member of the stent described in connection with Figure 3) to cover the central portion 10y stent 11a.
  • the upper distal portion of said member 12 cooperating with the central portion 10y of the stent 11a has lateral openings respectively cooperating with two extensions 31 and 32 provided respectively to enter said renal arteries.
  • the materials used to form said extensions 31 and 32 may be advantageously similar to those used to form the main member 12 of the stent.
  • the main member 12 of the stent is formed as a single piece comprising the tubular member and the two extensions 31 and 32.
  • the morphology of the patient or the configuration of the pathological vessel could be imagined (a single extension of the main member or a number of extensions greater than two). It suffices that the central portion 10y of the stent positioned at an arterial junction or venous has a mesh providing openings to facilitate blood flow.
  • the invention has been described in connection with and preferably with an abdominal aortic aneurysm in humans.
  • the invention applies naturally to any other endoprosthesis having a main member and a stent for which it is essential to prevent any risk of endoleak between the outer wall of the stent and the inner wall of the artery. pathological.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Prostheses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
EP12726818.3A 2011-05-10 2012-05-10 Endovaskularprothese Withdrawn EP2706955A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1154036A FR2975000B1 (fr) 2011-05-10 2011-05-10 Endoprothese vasculaire
PCT/FR2012/051038 WO2012153069A1 (fr) 2011-05-10 2012-05-10 Endoprothese vasculaire

Publications (1)

Publication Number Publication Date
EP2706955A1 true EP2706955A1 (de) 2014-03-19

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
EP12726818.3A Withdrawn EP2706955A1 (de) 2011-05-10 2012-05-10 Endovaskularprothese

Country Status (6)

Country Link
US (1) US20140088687A1 (de)
EP (1) EP2706955A1 (de)
JP (1) JP2014519372A (de)
AU (1) AU2012252196A1 (de)
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Also Published As

Publication number Publication date
FR2975000A1 (fr) 2012-11-16
WO2012153069A1 (fr) 2012-11-15
US20140088687A1 (en) 2014-03-27
FR2975000B1 (fr) 2013-06-14
JP2014519372A (ja) 2014-08-14
AU2012252196A1 (en) 2014-01-09

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