EP2689007A4 - Compositions et procédés pour la culture de cellules provenant d'un épithélium tubo-ovarien humain normal et de tumeurs tubo-ovariennes humaines - Google Patents

Compositions et procédés pour la culture de cellules provenant d'un épithélium tubo-ovarien humain normal et de tumeurs tubo-ovariennes humaines

Info

Publication number
EP2689007A4
EP2689007A4 EP12761150.7A EP12761150A EP2689007A4 EP 2689007 A4 EP2689007 A4 EP 2689007A4 EP 12761150 A EP12761150 A EP 12761150A EP 2689007 A4 EP2689007 A4 EP 2689007A4
Authority
EP
European Patent Office
Prior art keywords
tubo
human
ovarian
compositions
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP12761150.7A
Other languages
German (de)
English (en)
Other versions
EP2689007A1 (fr
Inventor
Tan A Ince
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brigham and Womens Hospital Inc
Whitehead Institute for Biomedical Research
Original Assignee
Brigham and Womens Hospital Inc
Whitehead Institute for Biomedical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham and Womens Hospital Inc, Whitehead Institute for Biomedical Research filed Critical Brigham and Womens Hospital Inc
Publication of EP2689007A1 publication Critical patent/EP2689007A1/fr
Publication of EP2689007A4 publication Critical patent/EP2689007A4/fr
Withdrawn legal-status Critical Current

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    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0681—Cells of the genital tract; Non-germinal cells from gonads
    • C12N5/0682—Cells of the female genital tract, e.g. endometrium; Non-germinal cells from ovaries, e.g. ovarian follicle cells
    • C—CHEMISTRY; METALLURGY
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • C—CHEMISTRY; METALLURGY
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
    • C12N2500/14—Calcium; Ca chelators; Calcitonin
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
    • C12N2500/16—Magnesium; Mg chelators
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    • C12N2500/00—Specific components of cell culture medium
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    • C12N2500/20—Transition metals
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
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    • C12N2500/00—Specific components of cell culture medium
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    • C12N2500/40—Nucleotides, nucleosides, bases
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    • C12N2500/46—Amines, e.g. putrescine
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/50—Soluble polymers, e.g. polyethyleneglycol [PEG]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/395—Thyroid hormones

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  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
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  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Reproductive Health (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP12761150.7A 2011-03-24 2012-03-23 Compositions et procédés pour la culture de cellules provenant d'un épithélium tubo-ovarien humain normal et de tumeurs tubo-ovariennes humaines Withdrawn EP2689007A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161467363P 2011-03-24 2011-03-24
US201161467949P 2011-03-25 2011-03-25
PCT/US2012/030446 WO2012129538A1 (fr) 2011-03-24 2012-03-23 Compositions et procédés pour la culture de cellules provenant d'un épithélium tubo-ovarien humain normal et de tumeurs tubo-ovariennes humaines

Publications (2)

Publication Number Publication Date
EP2689007A1 EP2689007A1 (fr) 2014-01-29
EP2689007A4 true EP2689007A4 (fr) 2014-09-03

Family

ID=46879764

Family Applications (1)

Application Number Title Priority Date Filing Date
EP12761150.7A Withdrawn EP2689007A4 (fr) 2011-03-24 2012-03-23 Compositions et procédés pour la culture de cellules provenant d'un épithélium tubo-ovarien humain normal et de tumeurs tubo-ovariennes humaines

Country Status (7)

Country Link
US (3) US20140170693A1 (fr)
EP (1) EP2689007A4 (fr)
JP (1) JP2014508540A (fr)
CN (1) CN103732737A (fr)
BR (1) BR112013029444A2 (fr)
CA (1) CA2831089A1 (fr)
WO (1) WO2012129538A1 (fr)

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Publication number Priority date Publication date Assignee Title
US9683217B2 (en) 2012-04-12 2017-06-20 University Of Miami In vitro culture conditions for T-cell acute lymphoblastic leukemia/lymphoma
US20140256044A1 (en) * 2013-03-07 2014-09-11 Mayo Foundation For Medical Education And Research Culture media
CA2914026A1 (fr) * 2013-06-04 2014-12-11 University Of Miami Dosages, procedes et kits d'analyse de la sensibilite et de la resistance a des medicaments anticancereux, donnant un pronostic de patient cancereux, et strategies therapeutiquespersonnalisees
WO2015048113A1 (fr) 2013-09-24 2015-04-02 University Of Miami Milieux de culture cellulaire
WO2015156929A1 (fr) * 2014-04-07 2015-10-15 The Trustees Of Columbia University In The City Of New York Procédé de culture de lignées cellulaires et d'organoïdes de vessie humaine, et leurs utilisations
WO2016049365A1 (fr) 2014-09-24 2016-03-31 Los Alamos National Security, Llc Dispositifs pour la gestion de fluides
US10588564B2 (en) * 2014-09-30 2020-03-17 Moein Health, LLC Method and kit for diagnosing and treating neoplastic tissue
WO2016167373A1 (fr) 2015-04-16 2016-10-20 日産化学工業株式会社 Additif pour milieu de culture, composition de milieu de culture, et procédé de culture de cellules ou de tissu l'utilisant
FR3035407B1 (fr) 2015-04-23 2022-06-17 Francais Du Sang Ets Procede de conservation de cellules, tissus ou organes en hypothermie
CN106906180A (zh) * 2016-12-28 2017-06-30 里程 一种具有生物活化作用的复合添加剂及其制备方法和用途
EP3604503A4 (fr) * 2017-03-28 2020-12-30 Ajinomoto Co., Inc. Additif pour milieu de maintien de dédifférenciation
WO2019127697A1 (fr) * 2017-12-29 2019-07-04 诺未科技（北京）有限公司 Système de culture permettant d'amplifier une cellule souche hématopoïétique et/ou une cellule progénitrice hématopoïétique et procédé s'y rapportant, cellule souche hématopoïétique et cellule progénitrice hématopoïétique
SG11202010129WA (en) * 2018-04-13 2020-11-27 Shanghai Lide Biotech Co Ltd Method for obtaining an animal model from conditionally reprogrammed cells and use of the animal model for screening anti-tumor drugs
CN109298174A (zh) * 2018-09-26 2019-02-01 姜云瀚 一种多色免疫荧光标记方法和成像方法
CN109652376B (zh) * 2019-01-08 2021-10-15 创芯国际生物科技(广州)有限公司 一种用于卵巢癌组织3d培养的培养基
CN110373388A (zh) * 2019-04-24 2019-10-25 博奥生物集团有限公司 一种用于类器官培养的培养基及类器官培养方法
CN110623982B (zh) * 2019-09-23 2023-04-25 四川大学华西医院 卵巢表面上皮细胞的3d-emt免疫活性制剂及制备与应用
CN110607278B (zh) * 2019-09-26 2021-06-01 深圳市拓普生物科技有限公司 肿瘤细胞培养物及其应用
CN111073847A (zh) * 2019-12-27 2020-04-28 中国福利会国际和平妇幼保健院 人类输卵管上皮细胞的培养方法
CN113493763A (zh) * 2020-03-18 2021-10-12 四川大学华西医院 可应用于基因编辑的小鼠卵巢原代细胞培养基及体外培养方法
CN115120784A (zh) * 2022-06-17 2022-09-30 朗肽生物制药股份有限公司 壳聚糖-氧化海藻酸钠水凝胶材料及其制备方法和应用
CN116179475B (zh) * 2023-04-23 2023-07-28 北京国卫生物科技有限公司 一种人脐静脉血管内皮细胞的分离培养方法

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US5710038A (en) * 1994-11-25 1998-01-20 Universite De Montreal Primary cultures of normal and tumoral human ovarian epithelium
WO2009023194A2 (fr) * 2007-08-10 2009-02-19 Whitehead Institute For Biomedical Research Système de culture tissulaire réactif aux hormones, et utilisations de celui-ci

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RU2404244C2 (ru) * 2008-08-20 2010-11-20 Учреждение Российской академии наук Институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова РАН СТАБИЛЬНАЯ КЛЕТОЧНАЯ ЛИНИЯ АДЕНОКАРЦИНОМЫ ЯИЧНИКА ЧЕЛОВЕКА SKOV-kat

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Publication number Priority date Publication date Assignee Title
US5710038A (en) * 1994-11-25 1998-01-20 Universite De Montreal Primary cultures of normal and tumoral human ovarian epithelium
WO2009023194A2 (fr) * 2007-08-10 2009-02-19 Whitehead Institute For Biomedical Research Système de culture tissulaire réactif aux hormones, et utilisations de celui-ci

Non-Patent Citations (2)

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Title
INCE TAN A ET AL: "Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes", CANCER CELL, CELL PRESS, US, vol. 12, no. 2, 14 August 2007 (2007-08-14), pages 160 - 170, XP002596863, ISSN: 1535-6108, DOI: 10.1016/J.CCR.2007.06.013 *
See also references of WO2012129538A1 *

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Publication number Publication date
US20140170693A1 (en) 2014-06-19
CN103732737A (zh) 2014-04-16
BR112013029444A2 (pt) 2017-01-17
US20190071634A1 (en) 2019-03-07
EP2689007A1 (fr) 2014-01-29
CA2831089A1 (fr) 2012-09-27
JP2014508540A (ja) 2014-04-10
WO2012129538A1 (fr) 2012-09-27
US20160319239A1 (en) 2016-11-03

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