EP2678658B1 - Vibrométrie ultrasonique avec ultrasons non focalisés - Google Patents

Vibrométrie ultrasonique avec ultrasons non focalisés Download PDF

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Publication number
EP2678658B1
EP2678658B1 EP12749825.1A EP12749825A EP2678658B1 EP 2678658 B1 EP2678658 B1 EP 2678658B1 EP 12749825 A EP12749825 A EP 12749825A EP 2678658 B1 EP2678658 B1 EP 2678658B1
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Prior art keywords
ultrasound
unfocused
shear waves
shear
transducer
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German (de)
English (en)
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EP2678658A4 (fr
EP2678658A1 (fr
Inventor
James F. Greenleaf
Shigao Chen
Armando Manduca
Pengfei Song
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Mayo Foundation for Medical Education and Research
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Mayo Foundation for Medical Education and Research
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N9/00Investigating density or specific gravity of materials; Analysing materials by determining density or specific gravity
    • G01N9/24Investigating density or specific gravity of materials; Analysing materials by determining density or specific gravity by observing the transmission of wave or particle radiation through the material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48Diagnostic techniques
    • A61B8/485Diagnostic techniques involving measuring strain or elastic properties
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/52Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/5215Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data
    • A61B8/5223Devices using data or image processing specially adapted for diagnosis using ultrasonic, sonic or infrasonic waves involving processing of medical diagnostic data for extracting a diagnostic or physiological parameter from medical diagnostic data
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/04Analysing solids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/04Analysing solids
    • G01N29/07Analysing solids by measuring propagation velocity or propagation time of acoustic waves
    • G01N29/075Analysing solids by measuring propagation velocity or propagation time of acoustic waves by measuring or comparing phase angle
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/22Details, e.g. general constructional or apparatus details
    • G01N29/221Arrangements for directing or focusing the acoustical waves
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/22Details, e.g. general constructional or apparatus details
    • G01N29/24Probes
    • G01N29/2456Focusing probes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01RMEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00Arrangements or instruments for measuring magnetic variables
    • G01R33/20Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48NMR imaging systems
    • G01R33/4808Multimodal MR, e.g. MR combined with positron emission tomography [PET], MR combined with ultrasound or MR combined with computed tomography [CT]
    • G01R33/4814MR combined with ultrasound
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01SRADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S7/00Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
    • G01S7/52Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
    • G01S7/52017Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
    • G01S7/52023Details of receivers
    • G01S7/52036Details of receivers using analysis of echo signal for target characterisation
    • G01S7/52042Details of receivers using analysis of echo signal for target characterisation determining elastic properties of the propagation medium or of the reflective target
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16HHEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/30ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/46Ultrasonic, sonic or infrasonic diagnostic devices with special arrangements for interfacing with the operator or the patient
    • A61B8/461Displaying means of special interest
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00Indexing codes associated with group G01N29/00
    • G01N2291/02Indexing codes associated with the analysed material
    • G01N2291/024Mixtures
    • G01N2291/02475Tissue characterisation
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00Indexing codes associated with group G01N29/00
    • G01N2291/02Indexing codes associated with the analysed material
    • G01N2291/028Material parameters
    • G01N2291/02827Elastic parameters, strength or force
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00Indexing codes associated with group G01N29/00
    • G01N2291/04Wave modes and trajectories
    • G01N2291/042Wave modes
    • G01N2291/0422Shear waves, transverse waves, horizontally polarised waves
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01SRADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S15/00Systems using the reflection or reradiation of acoustic waves, e.g. sonar systems
    • G01S15/88Sonar systems specially adapted for specific applications
    • G01S15/89Sonar systems specially adapted for specific applications for mapping or imaging
    • G01S15/8906Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques
    • G01S15/8909Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques using a static transducer configuration
    • G01S15/8915Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques using a static transducer configuration using a transducer array
    • G01S15/8927Short-range imaging systems; Acoustic microscope systems using pulse-echo techniques using a static transducer configuration using a transducer array using simultaneously or sequentially two or more subarrays or subapertures

Definitions

  • the present invention has been described with respect to the detection of shear waves with unfocused ultrasound, it will be appreciated by those skilled in the art that the present invention may also be applicable for detecting other tissue deformations resulting from an unfocused ultrasound push beam.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acoustics & Sound (AREA)
  • Physiology (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Remote Sensing (AREA)
  • Radar, Positioning & Navigation (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Pulmonology (AREA)
  • Theoretical Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Primary Health Care (AREA)
  • Epidemiology (AREA)
  • Databases & Information Systems (AREA)
  • Data Mining & Analysis (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)

Claims (5)

  1. Système pour mesurer une propriété mécanique d'un sujet, le système comprenant :
    a) un réseau de transducteurs à ultrasons configurés pour produire des ondes de cisaillement en mesure de se propager dans un sujet en appliquant au moins un faisceau ultrasonore non focalisé au sujet ;
    b) un dispositif de détection configuré pour acquérir des données de mesure pour mesurer au moins un emplacement dans le sujet dans lequel les ondes de cisaillement produites par l'émetteur sont présentes, dans lequel le dispositif de détection est un dispositif à ultrasons et les données de mesure sont acquises en appliquant une énergie à l'au moins un emplacement dans le sujet ;
    c) un dispositif de commande configuré pour calculer une propriété mécanique du sujet en utilisant les données de mesure acquises par le dispositif de détection ;
    caractérisé en ce que le dispositif de commande est programmé pour amener le réseau de transducteurs à ultrasons à produire simultanément une pluralité de faisceaux ultrasonores non focalisés s'étendant vers l'extérieur à partir du réseau de transducteurs à ultrasons dans un motif en forme de peigne pour appliquer la pluralité de faisceaux ultrasonores non focalisés de manière à produire des ondes de cisaillement qui se propagent dans le sujet.
  2. Système selon la revendication 1, dans lequel le dispositif à ultrasons est configuré pour appliquer l'énergie ultrasonore sous la forme d'au moins une parmi une énergie ultrasonore focalisée et une énergie ultrasonore non focalisée.
  3. Système selon la revendication 1, dans lequel le dispositif de commande est programmé pour amener le réseau de transducteurs à ultrasons à produire la pluralité de faisceaux ultrasonores non focalisés espacés de manière régulière sur une surface du réseau de transducteurs à ultrasons.
  4. Système selon la revendication 1, dans lequel le dispositif de commande est configuré pour :
    former un premier sous-ensemble de données de mesure à partir des données de mesure, le premier sous-ensemble de données de mesure correspondant à des mesures d'ondes de cisaillement se propageant dans une première direction ;
    former un deuxième sous-ensemble de données de mesure à partir des données de mesure, le deuxième sous-ensemble de données de mesure correspondant à des mesures d'ondes de cisaillement se propageant dans une deuxième direction ; et
    combiner sélectivement le premier sous-ensemble de données de mesure et le deuxième sous-ensemble de données de mesure.
  5. Système selon la revendication 4, dans lequel la première direction est une direction de gauche à droite et la deuxième direction est une direction de droite à gauche.
EP12749825.1A 2011-02-25 2012-02-27 Vibrométrie ultrasonique avec ultrasons non focalisés Active EP2678658B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161446839P 2011-02-25 2011-02-25
PCT/US2012/026769 WO2012116364A1 (fr) 2011-02-25 2012-02-27 Vibrométrie ultrasonique avec ultrasons non focalisés

Publications (3)

Publication Number Publication Date
EP2678658A1 EP2678658A1 (fr) 2014-01-01
EP2678658A4 EP2678658A4 (fr) 2018-01-10
EP2678658B1 true EP2678658B1 (fr) 2022-09-14

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Country Status (7)

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US (1) US11172910B2 (fr)
EP (1) EP2678658B1 (fr)
JP (1) JP6067590B2 (fr)
KR (1) KR101929198B1 (fr)
CN (1) CN103492855B (fr)
BR (1) BR112013021791B1 (fr)
WO (1) WO2012116364A1 (fr)

Cited By (1)

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US11000626B2 (en) 2011-06-03 2021-05-11 Allergan Industrie, Sas Dermal filler compositions including antioxidants

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CN103492855A (zh) 2014-01-01
EP2678658A4 (fr) 2018-01-10
BR112013021791B1 (pt) 2020-11-17
EP2678658A1 (fr) 2014-01-01
KR20140034161A (ko) 2014-03-19
JP6067590B2 (ja) 2017-01-25
BR112013021791A2 (pt) 2016-10-18
CN103492855B (zh) 2016-03-30
US11172910B2 (en) 2021-11-16
KR101929198B1 (ko) 2018-12-14
US20140046173A1 (en) 2014-02-13

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