EP2654665A2 - Procédé pour développer une composition liquide à appliquer sur la peau sous forme de mousse ainsi que composition applicable topiquement - Google Patents

Procédé pour développer une composition liquide à appliquer sur la peau sous forme de mousse ainsi que composition applicable topiquement

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Publication number
EP2654665A2
EP2654665A2 EP11801553.6A EP11801553A EP2654665A2 EP 2654665 A2 EP2654665 A2 EP 2654665A2 EP 11801553 A EP11801553 A EP 11801553A EP 2654665 A2 EP2654665 A2 EP 2654665A2
Authority
EP
European Patent Office
Prior art keywords
extract
foam
composition
oil
ppg
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP11801553.6A
Other languages
German (de)
English (en)
Inventor
Bernd G. Seigfried
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mika Pharma Gesell fur Entwicklung und Vermarktung Pharm Prod mbH
Original Assignee
Mika Pharma Gesell fur Entwicklung und Vermarktung Pharm Prod mbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mika Pharma Gesell fur Entwicklung und Vermarktung Pharm Prod mbH filed Critical Mika Pharma Gesell fur Entwicklung und Vermarktung Pharm Prod mbH
Publication of EP2654665A2 publication Critical patent/EP2654665A2/fr
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/046—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/55—Phosphorus compounds
    • A61K8/553—Phospholipids, e.g. lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F22/00—Methods or apparatus for measuring volume of fluids or fluent solid material, not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30—Characterized by the absence of a particular group of ingredients

Definitions

  • the present invention relates to a method for developing! treatment of a foam to be applied to the skin liquid cosmetic composition having the features of the preamble of claim 1 and a corresponding topically
  • the underlying liquid is foamed exclusively mechanically.
  • the underlying liquid composition which is foamed mechanically,
  • Alkylamidobetaine solution has.
  • the composition described in this example is provided with lecithin, this lecithin serving exclusively to form liposomes.
  • DE 197 40 095 A proposes to foam the liquid composition to be measured in such a way that a stirrer with a predetermined profile is used for this, which is driven with a predetermined number of revolutions. The foam thus produced is visually measured.
  • a development of this foam measuring method is finally described in EP 1 092 970 Bl, this development differs from the previously described with reference to DE 197 40 095 A measuring technique differs in that an automatic, taking place via measuring electrodes Schaum Wegnbe tuning is provided.
  • This measuring method which is referred to in the present text as "SITA Meßve" thus allows, on the one hand, the foam volume and on the other hand, the foam stability of liquids, especially dyeing and cleaning solutions, electroplating baths, emulsions, detergents, body care products or of beer, to determine this gives a quality statement to the aforementioned foamable
  • liquids are to be developed in the cosmetic area, which are foamable and thus applied as foam
  • the usual procedure is to select a cosmetically-active liquid which is then tried by varying the technique of mechanical foaming, in particular by varying the air pressure, the geometry and design of the foam head and the valve of a corresponding foam applicator. is foamed.
  • a development process for foamable cosmetic liquid compositions in the origin is very time-consuming and also has the disadvantage that in a variation of the design of the previously mentioned parameters of the mechanical foam applicator with respect to its composition may differ and inhomogeneous foam itself.
  • the present invention is therefore based on the object of providing a process for developing a liquid cosmetic composition to be applied as a foam to the skin, with which the development time for such cosmetic compositions is considerably shortened and the development as a whole is considerably simplified.
  • the present invention is based on the object, a topically applied as a foam liquid
  • said topically administrable composition has preferably been developed according to the aforementioned development method.
  • the first object is achieved by a method having the characterizing features of claim 1 and the further hereafter object is achieved by a topically administrable composition having the characterizing features of claim 10.
  • the process according to the invention for the development of a liquid cosmetic composition to be applied as a foam to the skin which comprises as minimum constituents a solvent, a cosmetic active substance and a foaming agent, provides for the foam volume and the
  • Foam stability can be determined according to a standardized SITA measurement method, wherein no blowing agent is used in this measurement method.
  • Foaming agent which varies at least one solvent and the at least one cosmetic active ingredient of their chemical nature and / or their concentration until the foam thus produced by the SITA measuring method under standardized conditions has a foam volume of at least 400 ml, in particular a foam volume between 450 ml and 1200 ml and preferably has a foam volume between 600 ml and 950 ml.
  • the foam must have such a foam stability that after a residence time of up to fifteen minutes and in particular after a residence time of up to eight minutes at least 50% of the foam volume and in particular between 55% and 100% of the foam volume and preferably between 75% and 90% of the volume of foam originally present immediately after the foam is produced.
  • the development process according to the invention thus prescribes, in the liquid cosmetic composition which is intended to form the foam when used without the use of a propellant, substances of at least one of content (solvent, cosmetic active ingredient and foaming agent) Their chemical nature and / or their concentration may be varied until, under standardized conditions, a foam can be produced according to the SITA measurement method, the foam volume of which has the previously quantified volumes and its foam stability the previously quantified properties.
  • the inventive method described above has a number of advantages. Thus, it was first surprisingly found that the process according to the invention permits a particularly simple and rapid development of such liquid cosmetic compositions which can be foamed reproducibly without the use of a blowing agent with a series of foam applicators, so that in the
  • kosher foams can be developed which are particularly reproducible with regard to their foam consistency and their foam composition. If, for example, the goal of such a development is to provide a liquid composition whose foam, after foaming by means of a suitable mechanical foam applicator, should have a relatively short stability, so that it rapidly disintegrates after being applied to the skin, then one varies Process according to the invention, the chemical nature and / or the concentration of the ingredients until the SITA measurement process results in a foam whose foam stability is characterized in that within two to four minutes, the foam volume is still a value between 50% and 70% of the foam volume that was originally present.
  • the chemical nature and / or the concentration of the minimum constituents of the liquid composition which later forms the foam should be varied so as to result in a foam whose foam stability is so high. that after eight to fifteen minutes still between 75% and 90% of the foam volume is present, based on the
  • the method according to the invention proposes a standardized method in which, by varying the chemical nature of the ingredients and / or their concentration, a foam quantified in terms of foam volume and foam stability in the above sense can be developed, which is accordingly applied to the skin, the hair or the nails is to be used in humans and animals.
  • skin used in the present specification not only covers the human or animal body skin, but also includes hair, nails or hooves of humans or animals.
  • Nomenclature Cosmetic Ingredients are exclusively or predominantly determined externally on the body of a human or animal or in his oral cavity for cleaning, be used to protect, to maintain a good condition, to perfume, to change the appearance or to influence the body odor.
  • a first development of the method according to the invention for developing a liquid cosmetic composition to be applied as a foam to the skin provides that a correlation is established between the foam specified according to the SITA method and the desired cosmetic properties.
  • the term "desired cosmetic properties” includes, in particular, care, protective, antiperspirant, moisturizing, skin-, nails- or hair-conditioning, smoothing, tanning and / or moisturizing properties, the fine distribution and uniformity of the distribution of the foam or the cosmetic active ingredient contained therein and / or to understand the effects caused thereby and desired.
  • the liquid composition to be frothed up by the SITA measurement method is varied the nature and / or concentration of the ingredients such that the foam produced a relatively low foam volume, in particular a foam volume between 450 ml and 600 ml, and a relatively low foam stability, in particular a foam stability after up to eight minutes between 55% and 75 % of the foam volume that was originally present immediately after the generation of the foam.
  • another embodiment provides that a foam applicator is selected for the mechanical foaming of the liquid composition, that of the liquid composition by the selected foam applicator a foam is produced and that a correlation is established between the properties, in particular the cosmetic properties, the foam produced via the foam applicator and the foam volume determined by the SITA measuring method and / or the foam stability.
  • This embodiment of the method according to the invention makes it possible to develop foams having defined foam volumes and foam stabilities, measured by the SITA measuring method, in a particularly simple and rapid manner by varying the type and / or concentration of the ingredients of the liquid cosmetic composition, which then correlate with the foams. the over the selected one
  • Foam applicator can later be applied as a foam on the skin.
  • such a foam is produced by the SITA foam measuring a foam density between 0.05 g / ml and 0.8 g / ml, preferably between 0.15 g / ml and 0.4 g / ml, it has been found that such liquid compositions give excellent foams which can be applied with a number of differently designed, mechanically operating foam applicators without the use of a propellant.
  • the solvent for the preparation of the liquid composition selected from the group comprising water, at least one alcohol, in particular at least one 1 to 3-valent alcohol, at least one polyalcohol and mixtures of the abovementioned solvents.
  • the solvents are 2-propanol,
  • Water includes all aqueous systems, especially aqueous buffer systems.
  • the foaming agent used is the cosmetic one
  • Particularly suitable for this purpose are active substances which are surface-active.
  • the foaming agent for the preparation of the liquid composition is selected from the group consisting of surfactants, in particular anionic, cationic, nonionic and ampholytic surfactants, silicones, fats, Fatty acids, fatty acid derivatives, phospholipids, sugar derivatives, lipids, in particular sphingolipids and glycolipids, and mixtures and derivatives of the aforementioned substances.
  • the foaming agents be it the cosmetic active ingredient itself or the foaming agents listed above, require that they be able to provide the above-described foam volumes and foam stabilities as soon as the liquid composition is purely mechanical without use a foaming agent is foamed.
  • the preferred surfactants include the
  • Alkyl ether phosphates the alkylbenzenesulfonates, the petroleum sulfonates, the olefin sulfonates and / or the
  • the silicones in particular include modified siloxanes, polydialkylsiloxanes and preferably linear or cyclic polydimethylsiloxanes.
  • Fats and modified fats in particular fatty acids, fatty acid derivatives, fatty acid esters, and synthetic, vegetable and animal phospholipids, in particular phosphatidylcholine and / or hydrogenated phospholipids and preferably hydrogenated phosphatidylcholine, belong in addition to the sphingolipids, glyco lipids and sugar derivatives, preferably sugar or Sorbate esters and polysorbates, the preferred foaming agents.
  • the fatty derivatives in particular include the sulfates of fatty acids, sulfonates of fatty acids, salts of the sulfates of fatty acids, salts of the sulfonates of fatty acids, soaps and mixtures and derivatives of the abovementioned substances
  • Foaming agent for use in the inventive method particularly suitable. This also applies to alkoxylated fatty acids and alkoxylated fatty acid derivatives, alkoxylated fatty alcohols, alkoxylated phenols and mixtures and derivatives of the aforementioned substances.
  • preferred surfactant foaming agents are selected from the group consisting of alkyl carboxylates, alkyl sulfates, alkyl sulfonates, alkyl ether carboxylates, sulfates of fatty acids, phosphates of fatty acids, sulfonates of fatty acids, salts of Sulfates of fatty acids, salts of the sulfonates of fatty acids, fatty acid amides, polyalkylenes, fluorosurfactants, soap, metal soaps, especially alkali soaps, such as preferably sodium, potassium and ammonium salts of aliphatic carboxylic acids, organic aminose, in particular organic amine soaps of aliphatic carboxylic acids, quaternary Ammonium compounds, in particular benzalkonium chloride, octadecylammonium chloride, sulfonium salts, amidoamines, fatty acid esters, preferably monoglycerol, diglycerol
  • cationic surfactants which are also particularly suitable as foaming agents, in the process according to the invention for the preparation of the liquid composition, substances are selected which comprise quaternary ammonium compounds, sulfonium salts, amidoamides and mixtures thereof and derivatives thereof.
  • Preferred ampholytic surfactants for the preparation of the liquid composition are selected from the group comprising betaine and betaine derivatives.
  • Preferred ampholytic surfactants for the preparation of the liquid composition are selected from the group comprising betaine and betaine derivatives.
  • Sorbitan fatty acid esters are formed with polyethylene glycol, in particular polyoxyethylene (20) sorbitan monolaurate,
  • active ingredients which are used in the process according to the invention, it should be noted that these are preferably those active ingredients, as described in more detail below in connection with the topically administrable composition according to the invention.
  • a foaming agent is a mixture of
  • Foaming agents selected said mixture of the foaming agent at least one phospholipid and at least one surfactant, such as those described above or below, used.
  • Phospholipids and the surfactant and the concentration of these two foaming agents can be prepared by the inventive method excellent foamable compositions that allow for foam stability and the foam volume optimized use of the foamed composition on the skin, hair, nails and / or hooves.
  • the cosmetic active ingredient and the foaming agent in further embodiments of the method according to the invention for the production of tion of the liquid composition which is foamed purely mechanical for its application, in particular a complexing agent, a buffer, a thickener, an antioxidant and / or a stabilizer provided.
  • a complexing agent e.g. a buffer, a thickener, an antioxidant and / or a stabilizer provided.
  • care must be taken to ensure that these previously listed ingredients can also have an influence on the foam volume and the foam stability, which, however, can be determined quite simply and without problems and within the shortest possible time and in a reproducible manner in the process according to the invention.
  • the present invention further relates, as already stated above, to a topically administrable composition having the features of the preamble of patent claim 10.
  • the topically administrable composition according to the invention which is preferably, but not exclusively, developed according to the inventive method described above, has at least one cosmetic active ingredient, at least one solvent and at least one foaming agent, this foaming agent is a phospholipid foaming agent. Furthermore, in the composition according to the invention, the at least one phospholipid foaming agent, the at least one solvent and the at least one active substance of their chemical nature and / or their concentration coordinated so that the composition without the use of an additional blowing agent is only mechanically alsturumbar.
  • the foam thus produced by the mechanical foaming during the application has a foam volume of at least 400 ml, preferably between 450 ml and 1200 ml and in particular a foam volume between 600 ml and 950 ml. Furthermore, the inventive
  • Foam stability can be determined by the standardized SITA measurement method.
  • the invention is applied to the skin, hair, nails or hooves
  • composition characterized in addition to the nature of their contents substances and / or their concentration nor by the foam produced therefrom, wherein the foam is specified and quantified by the standardized SITA measurement method in terms of foam volume and foam stability.
  • composition according to the invention has a number of advantages. If the composition according to the invention is applied to human or animal skin, hair, nails or hooves, the foam produced from the composition according to the invention initially has excellent adhesion at these application sites, so that it is not readily wiped off or dripped off in an undesired manner. Furthermore, from the inventive liquid
  • composition exclusively exclusively mechanically produced foam a homogeneous composition, wherein the cosmetic active ingredient in this foam is present in a particularly uniform finest distribution, so that after destruction of the foam after application of this FeinstVerannon is maintained in the case resulting on the skin surface liquid layer with the result that the cosmetic active ingredient is particularly evenly distributed.
  • This causes the active ingredient thus applied to produce high cosmetic efficacy, so that, if desired, the concentration of the active ingredient in the composition of the present invention can be reduced as compared with conventional compositions Alternatively or alternatively, the time intervals between successive applications can be extended accordingly. Due to the fact that in the composition according to the invention as a foaming agent at least one
  • phospholipidic foaming agent is present, causes this phospholipid foaming agent, that in addition skin irritation in particular be avoided even if the composition of the invention contains ingredients that would lead to irritation in particularly sensitive persons.
  • the foam produced from the composition according to the invention by the SITA measuring method has a foam density between 0.05 g / ml and 0.8 g / ml, preferably between 0.15 g / ml and 0.4 g / ml .
  • the composition according to the invention comprises, as solvent, in particular water, at least one alcohol, in particular at least one monohydric to 3-membered alcohol and / or at least one polyalcohol, such solvents also being especially suitable for such phospholipid
  • Foaming agents are selected which contain a vegetable ingredients, in particular soybeans isolated phospholipid and / or phospholipid mixture.
  • phospholipid mixture or phospholipids in the present description covers all phospholipids which are of plant origin, of animal origin or of synthetic origin.
  • these include the ester phospholipids, such as, preferably, phosphatidylcholine, lysophosphatidylcholine, phosphatidyl dylethanolamine, lysophosphatidylethanolamine, phosphatidylserine, lysophosphatidylserine, phosphatidylinositol, lysophosphatidylinositol, phosphatidylglycerol, diphosphatidylglycerol and the phosphatidic acid, the etherphospholipids, in particular cholineplasmalogen and ethanolamineplasmalogen, and the sphingosinephospholipids, in particular ceramidephosphorylcholine and phytoglycolipid, and derivatives of the esterphospholipids, the etherphospholipids and or sphingosine phospholipids, regardless of whether they are isolated from natural substances, such as, for example, plants or plant constituents, in particular plant seeds, or animal constituent
  • Phospholipids in particular hydrogenated or partially hydrogenated phosphatidylcholine.
  • Composition is one such active ingredient, which is for use in humans or animals on their skin, hair, nails or hooves, with particularly preferred active ingredients are selected from the group consisting of UV filters, antiperspirant agents, moisturizing agents, nail care
  • Active ingredients Active ingredients, hair conditioning agents, smoothing agents
  • Active ingredients Active ingredients, anti-dandruff agents, tanning agents, deodorizing agents, depilatory agents, and
  • the group of UV filters include in particular benzophenone-3, benzophenone-4, benzophenone-5, 3-benzylidene camphor, benzylidene Camphor sulfonic acid, butyl methoxydibenzoylmethane, camphor benzalkonium methosulfate, diethylhexyl butamido triazone
  • the group of antiperspirant active ingredients comprises in particular aluminum bromohydrate, aluminum chloride, aluminum chlorohydrate, aluminum chlorohydrex PEG, aluminum chlorohydrex PG, aluminum citrate, aluminum dichlorohydrate, aluminum dichlorohydrex PEG, aluminum dichlorohydrex PG, aluminum sesquichlorohydrates, aluminum sesquichlorohydrex PEG, aluminum sesquichlorohydrex PG, aluminum sulphate, aluminum zirconium octachlorohydrate, aluminum zirconium octachlorohydrex Gly , Aluminum Zirconium Pentachlorohydrate, Aluminum Zirconium Pentachlorohydrex Gly, Aluminum Zirconium Tetrachlorohydrate, Aluminum Zirconium Tetrachlorohydrex Gly, Aluminum
  • lipid-replacements include, in particular, calf skin extract, soybean acid, soybean palmitate, squalene, shark liver oil, steareth-10, stearic acid, stearyl alcohol, tall oil sterol, tallow acid, tallow alcohol,
  • Tridecyl alcohol ⁇ tridecyl alcohol
  • Triethylhexanoin Triheptylundecanoin, trilinoleic acid ⁇ Trilinoleic acid ⁇ , glycerol trilinoleic acid ester (trinlinolein), trilinolenin, trimyristin, triolein, tripalmitin,
  • the group of nagelwaysnden agents include in particular acetaldehyde.
  • the group of skin-protecting active ingredients comprises in particular Ahnfeltia concinna extract, allantoin acetylmethionine,
  • Glycyrrhetic acid allantoin polygalacturonic acid, Asparagopsis armata extract, Averrhoa carambola extract, benzylidenecamphor hydrolyzed collagen sulfonamide, betula alba juice, bis-hydroxyethyl biscetyl malonamide, brain extract, brassica
  • Colostrum cream colostrum serum, copper aspartate,
  • Diospyros kaki extract Diospyros kaki leaf extract, Diospyros kaki leaf powder, Durvillea antartica extract, Enteromorpha compressa extract, Fomes officinalis extract, Frangula alnus, Frangula alnus extract, Fucus serratus extract, Ganoderma lucidum extract, Gelidiella acerosa extract, Gelidium Cartilagineum extract, Geum rival extract, Geum urbanum extract, Gigartina stellata extract, Himanthalia elongata extract, Hordeum distichon extract, Hordeum vulgare, hydrolyzed wheat gluten, Hypericum perforatum extract, Hypnea musciformis extract, Ipomoea batatas extract, Ipomoea bona-nox extract, Kigelia africana extract, Lactobacillus Lac / Calcium / Phosphorus / Magnesium / Zin
  • Lactobacillus / algae ferment Lactobacillus / Eichornia crassipes ferment, Lactobacillus / alpighia glabra ferment,
  • Lactobacillus / Porphyridium ferment Lactobacillus / Skletonema ferment, Lactococcus ferment, Lactococcus lysate, Laminaria cloustoni extract, Laminaria digitata extract, Laminaria hyperborea extract, Laminaria japonica extract, Laminaria saccharina extract, Lithospermum officinale extract,
  • Lithothamnion calcareum extract Lotus corniculatus extract, Lycopsis arvernis extract, Magnolia acuminata extract,
  • Magnolia biondii extract Malpighia punicifolia, Malva
  • Mushroom extract Mammarian hydrolysate, Mammary extract, Manihot utilissima extract, Maris limus extract, Melanin, Mimosa tenuiflora bark extract, Mimosa tenuiflora leaf extract, Monascus / Oryza sativa feet, Muscle extract, Oleoyl, Tyrosine, Olivamidopropyl betaine, Orobanche rapum extract, Oryza sativa bran extract , Oryza sativa wax, Paeonia suffruticosa extract, Palmaria palmata extract, Panax ginseng extract, paraffin oil, liquid paraffin, Passiflora incarnata extract, Passiflora incarnata fruit extract, Passiflora incarnata oil, Passiflora quadrangularis extract, Passiflora quadrangularis fruit extract, Pelvetia canaliculata extract, Plantago ovata extract, Plantago ovata seed extract, pollen extract, Polygonum fagopyr
  • PVP / eicosene copolymer PVP / hexadecane copolymer, Pyrus comminis extract, Rehmannia Elata extract, Rhamnus purshiana extract, Rhododendron chrysanthum extract, Rhododendron ferrugineum extract, Rosa centifolia water, Rosa damascne distillate, Ruta graveolens extract, Saccharomyces / Glycine soy ferment,
  • Saccharomyces / Oryza sativa ferment Salix nigra extract, Salvia officinalis extract, Sargassum filipendula extract, Sarrez m fusiform extract, serum, Sophora japonica extract, Sophora japonica flower extract, Sphingolipid, Spirulina platensis extract, Stachys officinalis extract,
  • yeast agar glucan, yeast polysaccharides, yogurt, yogurt filtrate, yucca aloifolia extract, yucca brevifolia, yucca glanca extract, yucca schidigera extract and zinc oxide.
  • the group of skin care active ingredients include in particular Acacia eoncinna extract, Acacia dealbata extract, Acer
  • pseudoplatan extract acetylglutamine, acetylglutamine, acetylglycerylricinoleate, acetylmethionine, acetylmethionylmethylsilanol elastinate, Acidophilus / Vitis vinifera ferment, Acinetobacter ferment, Acorus calamus extract, Acorus calamus root powder, acrylate / carbamate
  • Copolymer Actinidia chinensis fruit extract, Actinidia chinensis seed, Actinidia chinensis seed oil, Actinidia chinensis water, Adansonia digitata oil, Adenosine, Cyclic adenosine phosphate, Adenosine phosphate, Adenosine triphiphisohate,
  • Aegopodium podagraria extract agarose, agave americana extract, agrimonia eupatoria extract, agropyron repens extract, ailanthus altissima extract, alanine glutamate,
  • AMP Hydroxypropyltrimonium
  • AMP isostearoyl hydrolyzed collagen
  • AMP isostearoyl hydrolyzed protein AMP isostearoyl hydrolyzed wheat protein
  • amyl salicylate amylase
  • Amyloglucosidase Anacyclus pyrethrum extract, Anchusa officinalis extract, Angelica acutiloba extract, Angelica cutiloba water, Angelica dahurica extract, Angelica keiskei extract, Angelica polymorpha sinensis extract, Aniba
  • rosaeodora extract Anigozanthos flavidus flower extract, Anona cherimolia extract, Anona muricata extract, Anthemis nobilis extract, Anthemis nobilis oil, Anthriscus cerefolium extract, Anthriscus sylvestris extract, Anthyllis vulneraria extract,
  • Protein extract Babusa arundinacea extract, Barosma betulina extract, Bean palmitate, Beer, Behena midopropyl dimethylamine behenate, behenylbenzoa, Belamcanda chinensis extract,
  • Benzyl hyaluronate benzyltrimonium hydrolyzed collagen, beta-carotene, betaglucan, beta-sitosterol, beta- sytosteryl acetate, betula platyphylla japonica extract,
  • Carboxyethylaminobutyric acid Carum carvi extract, Carum petroselinum extract, Carum petroselinum seed oil, Carya illinoensis oil, Casearia sylverstirs extract, Cassia
  • Centaurea cyanus Centaurea cyanus extract, Centaurea cyanus water, Centaurium erythraea extract, cephalin, ceramide 1, ceramide 1A, ceramide 2, ceramide 4, ceramide 5, ceramide 611, Ceramide 3, Cetearyl Dimethicone / Vinyl Dimetate Crosspolymer, Cetearyl Methicone, Cetearyl Stearate, Cetyl Glyceryl Ether, Cetyl PCA, CETYL PPG-2 ISODECETH-8 CARBOXYLATE,
  • Cetylricinoleic Acid Benzoate Cetyl PG Hydroxyethyldecanamide, Cetyl PG Hydroxyethyl Palmitamide, Chamazulen, Chenopodiura Ambrosioides Extract, Chenopodium Quinoa Extract, Chenopodium Quinoa Oil, Chimyl Alcohol, Chiting Glycolate, Chitosan Ascorbate, Chitonsanglucolate, Chitosan Salicylate, Chlorella Emersonii Extract, Chlorella Ferment, Chlorella Pyrenoidosa Extract,
  • Chlorella vulgaris extract chlorogenic acid, cholesteryl acetate, cholesteryl butyrate, cholesteryl chloride, cholesteryl
  • Chrysanthemum indicum extract Chrysanthellum parthenium extract, Chrysanthe11um sinense extract, Cichorium intybus extract, Cichorium intybus elate extract, Cistus incanus extract, Citrobacter / soy protein extract, Citrulline, Citrullus
  • Citrus aurantifolia extract Citrus aurantifolia juice, Citrus aurantifolia oil, Citrus aurantifolia peel extract, Citrus aurantium dulcis extract, Citrus aurantium dulcis flower extract, Citrus aurantium dulcis flower water, Citrus aurantium dulcis peel cera, Citrus aurantium dulcis
  • Shell extract Citrus aurantium dulcis seed extract, Citrus aurantium dulcis water, Citrus grandis extract, Citrus grandis juice, Citrus grandis leaf extract, Citrus grandis peel extract, Citrus grandis seed extract, Citrus nobilis extract, Citrus nobilis fruit extract, Citrus unshiu extract, Clematis vitalba extract, Cnidium officinale Extract,
  • COCODIMONIUM HYDROXYPROPYL SILK AMINO ACIDS COCOS nucifera extract, Cocos nucifera shell powder, Coffea arabica bean extract, Coffea arabica extract, Coffea robusta extract, Coix Lachryma jobi extract, Coix lachryma jobi oil, Coleus barbatus extract, Combretum micranthum extract, Commiphora abyssinica extract, connective tissue extract, upfer acetyl methionate,
  • Dimethiconol fluoroalcohol dilinoleic acid dimethiconol illipe butterate, dimethiconol cocum butterate, dimethiconollactate, dimethiconol mohwa butterate, dimethiconol sal butterate, dimethiconol / silsesquioxane copolymer,
  • Disodium adenosine triphosphate disodium cetearyl sulfosuccinate, disodium cocamido ea sulfosuccinate, disodium cocamido mipa sulfosuccinate, DISODIUM
  • Cocoamphodiacetate Dinatriura Cocoamphodipropionate
  • Disodium Cocopolyglucose Sulfosuccinate Disodium C12-15 Pareth Sulfosuccinate
  • Disodium Diglycerol Phosphate Disodium
  • crassifolium extract erucamidopropyl hydroxysultaine
  • Euphorbia hirta extract Euphrasia officinalis, Euphrasia officinalis extract, Evernia prunastri extract, Fabiana impricata extract, Faex, Faex extract, fermented vegetable, iron citrate, ferric aspartate, ferrous
  • Glucoheptonate Ferula foetida extract, Fibronectin, Ficus carica extract, Fluorine yeast derivative, Foeniculum vulgare extract, Foeniculum vulgare fruit, Foeniculum vulgare oil, Folic acid, Fragaria chiloensis extract, Fragaria vesca extract, Fragaria vesca fruit, Fragaria vesca juice, Fragaria vesca leaf extract Tract, Fragaria vesca seeds, Frangula alnus, Frangula alnus Extract, Fraxinus excelsior extract, Freesia refracta extract, Fucus vesicolosus extract, Fumaria officinalis extract, Galega officinalis extract, Galium aparine extract, Gallus extract, Garcinia cambogia extract, Gardenia tahitensis extract,
  • Glyceryl isostearate glyceryl oleate / elaidate, glyceryl ricinoleate SE, glyceryl stearate citrate, glyceryl stearate diacetate,
  • Glyceryl stearate lactate glyceryl stearate succinate
  • Glyceryl triacetylricinoleate Glycine, Glycine soy extract, Glycine soy flower, Glycine soybean seed extract, Glycine soy
  • Oil glycine soybean oil (unsaponifiable), glycine soy protein, glycine soya sprout extract, glycine soya sterol, glycogen,
  • glycoldibehenate glycol diethylhexanoate
  • glycol dioleate glycol distearate
  • glycol distearate glycol
  • Glycol montanate glycol oleate, glycol palmitate, glycol ricinoleate, glycol / butylene glycol montanate, glycolamide stearate,
  • Glycoproteins glycosaminoglycans, glycosphingolipids, glycyl-glycine, glycyrrhetinic acid, GLYCYRRHETI YL STEARATE,
  • Glycyrrhizic acid Gnaphalium leontopodium extract, Gnaphalium polycephalum extract, Gorgonia extract, Gossypium herbaceum extract, Gossypium herbaceum seed extract, Gossypium oil, Grindelia robusta extract, Guajacum officinale extract,
  • HYDROXYPROPYLTRIMOUM CHLORIDE Hamamelis virginiana Destil lat, Hamamelis virganiana extract, Hamamelis viganiana water, Harpagophytum procumbens extract, Hartingana madagascariensis extract, Herb extract, Hedera helix, Hedera helix extract, Hedychium coronarium extract, Hedychium spicatum extract, Helianthus annuus extract, Helianthus annuus seed extract, Helianthus annuus seed oil, Helianthus tuberosus extract , Heiichrysum arenarium extract, heliotropin, henna, heparin, heptylundecanol, Herniaria glabra extract, hexacosylglycol, hexacosylglycol isostearate, hexadecylmethicone,
  • orientalis extract hyaluronic acid, Hydrangea macrophylla extract, Hydrastis canadensis extract, Hydrastis canadensis root extract, hydrogenated butylene / ethylene / styrene copolymer, hydrogenated rapeseed oil, hydrogenated castor oil, hydrogenated castor oil hydroxystearate, hydrogenated castor oil isostearate, hydrogenated castor oil laurate, hydrogenated castor oil PEG -3-ester, hydrogenated castor oil stearate, hydrogenated castor oil triisostearate, hydrogenated castor oil trisostearin ester, hydrogenated coco glycerides, hydrogenated coconut acid, hydrogenated coconut oil, hydrogenated C6-14 olefin polymers, HYDROGENATED COTTONSEED GLYCERIDE,
  • HYDROGENATED COTTONSEED OIL hydrogenated C12-18 triglycerides
  • HYDROGENATED DITALLOWAMINE hydrogenated fish oil, hydrogenated honey, hydrogenated jojoba oil, hydrogenated jojoba wax, hydrogenated Laneth-5, hydrogenated lanolin, hydrogenated lanolin alcohol, hydrogenated lard, hydrogenated Schraalzglycerid, hydrogenated
  • HYDROGENATED PALM KERNEL GLYCERIDES HYDROGENATED PALM OIL
  • HYDROGENATED PALM / PALM KERNEL OIL PEG- 6 ESTERS hydrogenated peanut oil, hydrogenated polyisobutene, hydrogenated rapeseed oil, hydrogenated rice bran wax, hydrogenated shark liver oil, hydrogenated soybean oil, hydrogenated tallow, HYDROGENATED TALLOW
  • ALCOHOL HYDROGENATED TALLOW GLYCERIDE CITRATE, HYDROGENATED TALLOW GLYCERIDE LACTATE, hydrogenated tallowgyceride, hydrogenated tallow glyceride citrate, HYDROGENATED TALLOWOYL GLUTAMIC ACID, hydrogenated vegetable glycerides, hydrogenated vegetable glyceride citrate, hydrogenated vegetable oil, hydrolyzed actin, hydrolyzed egg white, hydrolyzed casein, hydrolyzed collagen, hydrolyzed conchiorin protein, hydrolyzed corn protein , hydrolyzed corn starch, hydrolyzed DNA, hydrolysed egg shell membrane,
  • hydrolyzed fibronectin hydrolyzed gadidae protein, hydrolyzed gelatin, hydrolyzed glycosaminoglycans, hydrolyzed glycyrrhizinate, hydrolyzed crayfish, hydrolyzed hair keratin, hydrolyzed hemoglobin,
  • hydrolyzed human placental protein hydrolyzed keratin, hydrolyzed lupine protein, hydrolyzed Maple sycamore protein, hydrolysed milk protein, hydrolyzed millet, hydrolyzed oatmeal, hydrolyzed oat protein, hydrolyzed oatmeal, hydrolyzed pea,
  • hydrolysed pea protein hydrolyzed pearl, hydrolyzed Placental protein, hydrolyzed potato protein,
  • hydrolyzed erythrocytes hydrolyzed reticulin
  • hydrolyzed rice bran protein hydrolyzed rice protein, hydrolysed R S, hydrolyzed rye, hydrolyzed
  • Serum protein hydrolyzed silk, hydrolyzed soy, hydrolysed soy protein, hydrolyzed soybean starch,
  • hydrolyzed spinal protein hydrolyzed sweet almond protein, hydrolysed vegetable protein, hydrolyzed wheat gluten, hydrolyzed wheat protein, hydrolyzed wheat protein / dimethicone copolyol phosphate copolymer, hydrolyzed wheat starch, hydrolyzed yeast, hydrolyzed yeast protein, hydrolyzed zein, hydrocapric acid,
  • Hydroxycinnamic acid hydroxyethylsorbitol, hydroxylated lanolin, hydroxylated lecithin, hydroxylated milk glycerides, hydroxylauric acid, hydroxylauroylphosphingosine,
  • Hydroxypropyltrimonium hydrolyzed silk Hydroxypropyltrimonium hydrolyzed soy protein, Hydroxypropyltrimonium hydrolyzed vegetable protein, Hydroxypropyltrimonium hydrolyzed wheat protein, Hex aquifolium extract, Inositol Hexa-PCA, Inula helenium extract, Iodized garlic, Iodized garlic extract, Iodinated hydrolyzed extensin, Ipomoea purga, Ipomoea purga resin, Iris germanica extract, isoamyl laurate, isobutylmyris a, isobutyl palmita, isobutyl pelargonate,
  • Isostearoyl hydrolyzed collagen isostearoyl isostearyl stearate, isostearyl alcohol, isostearyl avocadate,
  • Isostearylethylhexanoate isostearylglycerylerythrityl ether, isostearylisostearate, isostearyl lactate, isostearyl laurate, isostearylmyrista, isostearylneopentanoate,
  • Lard glycerides lauramidopropyl betaine, laureth-2-acetate, laureth-2-ethylhexanoate, laurin / palmitin / olein triglyceride, lauroylglutamic acid, lauroyl hydrolyzed collagen, lauroyl hydrolyzed elastin, lauroyl lysine, lauroylmethylalanine, lauryl acrylate / VA copolymer, laurylaminopropyl glycine,
  • chinensis extract lithium gluconate, Lithospermum erythrorhizon extract, liver extract, liver hydrolyzate, Lonicera japonica extract, Lonicera japonica leaf extract, Lupinus albus extract, Lupinus albus oil, Lupinus luteus extract, Luteum ovi extract, Lysine, lysine aspartate, lysine carboxymethyl cysteinate,
  • Lysine glutamate lysine hydrochloride, lysine lauroyl methionate, lysine PCA, lysine thiazolidine carboxylate, macadamia ternifolia extract, magnesium acetyl methionine, magnesium ascorbate,
  • Manganese powder manganese chloride, manganese gluconate, manganese PCA, Mangifera indica extract, Mangifera indica seed oil,
  • Mango Seed Oil PEG-70 Ester Mannitol, Maris a qa, Maris sal, Pumpkin Extract, Marrubium vulgare Extract, Marsdenia condurango Extract, Mea-hydrolyzed collagen, Mea-hydrolyzed silk,
  • Medicago sativa oil (unspotted), Melia azadirachta extract, Melia azadirachta leaf extract, Melissa officinalis seed oil, menthyl-PCA, Menyanthes trofoliata extract, Methicon,
  • Methiconine, methoxy-PEG-22 / dodecylglycol copolymer Methiconine, methoxy-PEG-22 / dodecylglycol copolymer
  • Methyl glucose dioleate methyl glucose isostearate
  • Hydroxypyrrolidine methylhydroxystearate, methyl isostearate, methyl laurate, methyl linoleate, methyl myristate, methyl oleate, methyl palmitate, methyl palmitate, methyl pelargonate,
  • Methylsilanolelastinate methyl silanolglycyrrhizina
  • Molybdenum aspartate Monosaccharide lactate condensate, Morus alba root extract, Morus bombycis root extract, Morus nigra root extract, Musa sapientium extract, Musa sapientium leaf extract, Mustela cera, Mustela oil, Myosotis sylvatica extract, Myreth- 2 myristate, Myreth-3 caprate, Myreth-3-ethylhexanoate,
  • Myristamidopropyl betaine myristoyl glutamic acid, myristoyl glycine / histidine / lysine polypeptide, myristoyl hydrolyzed collagen, myristoylmethylalanine, myristyl alcohol,
  • Myristyl betaine myristyl ethyl hexanoate, myristyl isostearate, myristyl lactate, myristyl lignocerate, myristyl myristate,
  • Neopentyl glycol diethylhexanoate neopentyl glycol diisosteara
  • neopentyl glycol dilaurate NEORUS COGENINE
  • Nerium oleander extract Nerium oleander extract
  • nerve extract Nico iana tabacum extract
  • Nicotinyl tartrate Nymphaea alba extract, Nymphaea alba root extract, Ocimum tenuiflorum extract, Octadecan,
  • Pantothenic acid polypeptides papain, Passiflora edulis extract, Passiflora edulis fruit extract, Passiflora incarnata extract, Passiflora incarnata fruit extract, Passiflora laurifolia extract, Passiflora laurifolia fruit extract, Passiflora
  • Poligonatum multiflorum extract Polygonatum officinale extract, Polygonum bistorta extract, Polygonum multiflorum extract, Polygonum multiflorum root extract,
  • Potassium aspartate potassium cocoyl hydrolyzed grain protein, potassium cocoyl hydrolyzed potato protein, potassium cyanate, potassium DNA, potassium glucoheptonate, potassium glycyrrhizinate,
  • carrageenan potassium undecylenoyl hydrolyzed collagen, potassium undecylenoyl hydrolyzed grain protein,
  • hydrolysed wheat protein potassium yeast derivative, PPG-1-ceteth-1, PPG-1-ceteth-5, PPG-1-ceteth-10, PPG-1-ceteth-20,
  • Prunus persica leaf extract Prunus serotina, Prunus serotina bark extract, Prunu serotina extract, Prunus speciosa extract, Prunus spinosa juice, Psalliota campestris extract, Pseudotsuga meziesii extract, Psidium guajava extract,
  • Psoralea corylifolia extract Psoralea corylifolia extract, PTFE, Pueraria lobata extract, Pulmonaria officinalis extract,
  • Pyridoxine dicaprylate pyridoxine dilaurate, pyridoxine dioctenoate, pyridoxine dipalmitate, pyridoxine glycyrrhetinate, pyridoxine HCl, pyridoxine tripalmitate, Pyrus communis extract, Pyrus cydonia extract, Pyrus malus extract, Pyrus malus leaf extract, Pyrus malus pectin extract, Pyrus malus peel wax, Pyrus malus water, Pyrus sorbus extract, Quassia amara Extract,
  • hydrolyzed keratin quaternium-hydrolyzed milk protein, quaternium-hydrolyzed silk, quaternium-79 hydrolyzed soy protein, quaternium-hydrolyzed wheat protein, raffinose myristate, raffinose oleate, ranunculus ficaria extract, Raphanus sativus extract, Raphanus sativus seed extract, Rauwolfia serpentina extract, Rehmannia
  • chinensis extract reseda luteola extract, resorcinol acetate, retinol, retinyl acetate, retinyl linoleate, retinyl palmitate, retinyl propionate, Rhamnus purshiana extract, Rheum palmatum extract, Rheum palmatum root extract, Rheum undumatum extract, Rhus glabra extract, Ribes nigrum extract, riboflavin, riboflavin tetra acetate, ricinolamidopropyl betaine , Ricinus communis oil, RNS, Robinia pseudoacacia extract, Romneya coulteri extract, Rosa canina fruit oil, Rosa canina leaf extract, Rosa canina seed extract, Rosa gallica extract, Rosa moschata seed oil, Rosin hydrolyzed collagen, Rosmarinus officinalis leaf powder, Royal jelly, Royal jelly Extract, royal jelly powder, Rubia tinctorium, Rub
  • Saccharomyces ferment Saccharomyces lysate extract, Saccharomyces polypeptides, Saccharomyces / calcium erment, Saccharomyces / copper ferment, Saccharomyces / fluorine ferment, Saccharomyces / germanium ferment, Saccharomyces / iron ferment, Saccharomyces / magnesium ferment, Saccharomyces / magnesium ferentene hydrolyzate, Saccharomyces / manganese ferment,
  • Saccharomyces / Maris sal ferment Saccharomyces / alium ferment
  • Saccharomyces / Kaiium ferment hydrolyzate
  • Saccharomyces / silicon ferment Saccharomyces / zinc ferment
  • Saccharum officinarum extract Saccharum officinarum powder
  • Sales Salicornia herbacea extract, Salix alba bark extract, Salix alba flower extract, Salix alba leaf extract, Salmo oil, Salmo ovum extract, Salvia hispanica extract, Salvia hispanica oil, Salvia officinalis, Salvia officinalis extract, Salvia officinalis water, Salvia sclarea extract, Sambucus
  • canadensis extract canadensis extract, Sambucus nigra, Sambucus nigra berry extract, Sambucus nigra extract, Sambucus nigra water,
  • Sanguinaria canadensis extract Sanicula eurpaea, Santalum album, Santalum album extract, Santalum album seed oil, Sapindus mukurossi peel extract, Sapindus trifollatus extract,
  • hydrolysed collagen sodium palmitoyl hydrolyzed wheat protein, sodium pantotheninesulfonate, sodium PCA, sodium PCA methylsilanol, sodium polyglutamate,
  • RNA RNA
  • cymnol sulfate sodium stearoyl casein
  • sodium stearoyl chondroitin sulfate sodium stearoyl DNA
  • sodium stearoyl glutamate sodium riboflavin phosphate, sodium RNA, sodium cymnol sulfate, sodium stearoyl casein, sodium stearoyl chondroitin sulfate, sodium stearoyl DNA, sodium stearoyl glutamate,
  • sucrose preference sucrose polylurate
  • sucrose polylinoleate sucrose polyoleate
  • sucrose tribehenate sucrose tristearate, sulfurized
  • Jojoba Oil Sunflower Seed Oil Glyceride, Sunflower Seed Oil Glyceride, Sus Extract, Swertia japonica Extract, Symphytum officinale Leaf Extract, Synthetic Jojoba Oil, Tabebuia Extract, Tabebuia impetiginosa Beef Extract, Tabebuia
  • Tallow glycerides tallow amidopropyl betaine, tallow amidopropyl hydroxysultaine, tamarind polysaccharides, Tanacetum vulgar extract, Taraxacum officinale extract, Taraxacum officinale root, TEA-cocoyl hydrolyzed collagen, TEA-cocoyl hydrolyzed soy protein, TEA-isostearoyl hydrolyzed collagen, TEA-lactate, TEA -laneth-5 sulfate, TEA-lauroyl collagen amino acids, TEA-lauroyl hydrolyzed collagen, TEA-lauroyl keratin amino acids, TEA-myristol hydrolyzed collagen, TEA-oleoyl hydrolyzed collagen, TEA-U DECYLENOYL HYDROLYZED COLLAGEN, Tecoma lapacho ex - Tract, Terminalie catappa extract, testes extract,
  • Thaumatococcus danielli extract Theobroma cacao extract, theobromine, thiamine HCl, thiamine nitrate, thurfhenyl nicotinate HCl, thuja occidentalis extract, thuja occidentalis root extract, thymus extract, thymus hydrolyzate, Tilia americana extract, Tilia cordata oil, Tilia tomentosa extract, Tillandsia
  • Triarachidine tribehenin, tricaprin, tricaprylin
  • Tridecylbehenate tridecylcocoate, tridecylethylhexanoate,
  • Triheptanoin trohydroxymethoxysteaine, trihydroxypalmitamido hydroxypropyl myristyl ether, trihydroxystearin,
  • Trilauryl phosphate trilinoleic acid, trimethylolpropane
  • Triisostearate trimethylolpropane trilaurate
  • Trimethylsiloxysilicate trimethylsil lamodimethicone
  • Trimyristin trioctyldodecyl citrate, trioelin, triolein PEG-6 ester, trioleyl phosphate, tripalmitin, triphenyltrimethicone, tripropylene glycol citrate, tristearin, tristearyl citrate,
  • Triticum vulgare bran extract Triticum vulgare extract, Triticum vulgare germ, Triticum vulgare germ extract, Triticum vulgare germ oil (unsaponifiable), Triticum vulgare germ protein, Triticum vulgare gluten, Triticum vulgare powder, Triticum vulgare protein, Triticum vulgare sprout extract,
  • Vinylcaprolactam / PVP / dimethylaminoethyl methacrylate copolymer Viola yedoensis extract, Viscum album extract, Vitis vinifera extract, Vitis vinifera juice, Vitis vinifera leaf extract, Vitis vinifera root extract, Vitreoscilla ferment extract, Wheat amino acids, Wheat germic acid, Wheat germ glycerides, Wheat germamide dea, Wheat germ amidopropyl betaine ⁇ wheat
  • Wisteria sinensis extract Wisteria sinensis extract, xanthine, xylitol, yeast palmitate, yucca vera extract, zanthoxylum alatum extract, zanthoxylum
  • araericanum extract Zanthoxylum piperi extract, Zea mays germ extract, Zea mays gluten protein, Zea mays oil
  • Zinc pentadecentricarboxylate Zinc pentadecentricarboxylate, zinc yeast derivative, Zizyphus joazeiro extract, Zizyphus jujuba extract and Zizyphus spina christi.
  • the group of hair conditioning agents includes, in particular, Abies balsamea extract, acetylamido ethoxybutyltrimonium chloride, acetylmethionyl methylsilanolelastina, acrylate / carbara copolymer, aluminum capryloyl hydrolyzed collagen, aluminum
  • undecylenoyl collagen amino acids aminobispropyl dimethicone, aminobutyric acid, aminopropyllaurylglutamine,
  • hydrolysed soy protein AMP isostearoyl hydrolyzed wheat protein, apricot amidopropyl ethyldimonium ethosulfate, arctium extract, arctium minus extract, argemone
  • mexicana oil arginine aspartate, arginine glutamate, avena sativa protein, babassuaraidopropalkonium chloride, beer,
  • Behentrimoniumchlorid Behentrimoniummethosulfat
  • Caprylic / Capramidopropylbetaine Capryloyl Collagen Amino Acids, Capryloyl Hydrolyzed Collagen, Capryloyl Hydrolyzed Keratin, Capryloyl Keratin Amino Acids, Capryloyl Pea Ami Osaurem, Capryloyl Quinoa Amino Acids, Capryloyl Silk amino acids, carpylylglycol, caprylylhydroxyethylimidazoline, carboxybutylchitosan, carpronium chloride, casein, ceramide 1, ceramide 1A, ceramide 2, ceramide 4, ceramide 5, ceramide 6 II, ceresin, ceteareth-27, ceteartrimonium chloride,
  • Cetylpyridinium chloride C olecalceferol polypeptide, Cinnamomum cassia, Cinnamomum cassia extract, Cinnamomum cassia oil, Cinanmomum lourerase extract, Citrus aurantifolia extract, Citrus aurantifolie juice, Citrus aurantifolia oil, Citrus aurantifolia shell extract, Cocamidopropyldimethylamine, Cocamidopropyldimethylamine dihydroxymethylpropionate,
  • Cocamidopropyldimethylaminohydroxypropyl-hydrolyzed collagen cocamidopropyldimethylammonium C8-16 isoalkylsuccinyl-lactoglobulinsulfonate, cocamidopropylethyldimoniumethosulfate,
  • Soy protein cocodimonium hydroxypropyl hydrolyzed wheat protein, cocodimonium hydroxypropyl silk amino acids, coco ethyldimonium ethosulfate, coco hydroxy sultaine, cocoorpholine oxide, cocos nucifera extract, cocos nucifera shell powder, cocotrimonium methosulfate, cocoyl glutamic acid, cocoyl hydrolyzed collagen, cocoyl hydrolyzed keratin, cocoyl hydrolyzed soy protein, cocoylhydroxyethylimidazoline, cocoylhydroxyethylimidazolinium PG-chloride phosphate,
  • Corn gluten amino acids ais starch / acrylamide / sodium acrylate copolymer, cyclohexasiloxane, cyclomethicone, cyclopentasiloxane, cyclotetrasiloxane, cyclotrisiloxane, cysteine, cystine, Datem, DEA-lauraminopropionate, decarboxycarnosine HCl, decylamine oxide, dextranhydroxypropyltriraonium chloride, diarainopyrimidine oxide, diammoniumdimethicone copolyolsulfosuccinate,
  • Tallowamidoethylhydroxyethylmonium methosulfite dihydrogenated tallowamidoethylmonium chloride, dihydrogenated tallowdimonium chloride, dihydrogenated tallowethylhydroxyethylmonium methosulfate,
  • Copolymer dihydroxypropyl PEG-5 linolammonium chloride phosphate, diisostearamidopropylpoxypropylmonium chloride id,
  • Dimethicone copolyol mango butterate dimethicone copolyol mohwabate, dimethicone copolyol salt butterate,
  • Dipalmitoylhydroxyproline dipalmitoylethyldimonium chloride, dipalmitoylethylhydroxyethylmonium methosulfate,
  • Disodium steariminodipropionate disodium stearoamphodiacetate, disodium stearoyl glutamate, disodium tallow amphodiacetate,
  • Dodecylhexadecy1trimonium chloride DODECYL YLYLDI RIMONIUM CHLORIDE, elastin amino acids, erucalkonium chloride,
  • Erucamidopropyl hydroxysultaine ETHYL APRICOT KER ELATE, Ethyl ester of hydrolyzed animal protein, Ethyl ester of hydrolyzed keratin, Ethyl ester of hydrolyzed silk, Ethyl glutamate,
  • Glyceryl collagenate glycine, glycine so a extract, glycine soy flower, glycoproteins, glycylglycine, gutta percha, hamamemis virginiana distillate, hamamelis virginiana extract, hamamelis virginiana water, heart hydrolyzate, helianthus annuus extract, hematin, hexyldecyl ester of hydrolyzed collagen,
  • Tallowylglutamic acid hydrogenated tallowtrimonium chloride, hydrolyzed actin, hydrolyzed albumin, hydrolyzed casein, hydrolyzed collagen, hydrolyzed
  • Conchiorin protein hydrolyzed maize protein, hydrolyzed DNA, hydrolysed egg protein, hydrolyzed elastin, hydrolyzed extensin, hydrolyzed fibronectin,
  • hydrolyzed glycosaminoglycans hydrolyzed hair keratin, hydrolyzed hemoglobin, hydrolyzed
  • Human placental protein hydrolyzed keratin, hydrolyzed lupine protein, hydrolyzed maple sycamore protein, hydrolyzed milk protein, hydrolyzed oatmeal, hydrolyzed oat protein, hydrolyzed oatmeal, hydrolyzed pea protein, hydrolyzed placental protein, hydrolyzed potato protein, hydrolyzed reticulin, hydrolyzed rice bran protein, hydrolyzed rice protein, hydrolyzed RNA, hydrolyzed serum protein , hydrolyzed silk, hydrolyzed soy protein, hydrolyzed soy protein / dimethicone copolyol acetate, hydrolyzed spinal protein, hydrolyzed sweet almond protein, hydrolyzed vegetable protein, hydrolyzed wheat protein, hydrolyzed wheat protein / dimethicone copolyol acetate, hydrolyzed wheat protein / PEG-20 acetate copolymer, hydrolyzed wheat starch, hydrolyzed yeast protein, hydrolyzed
  • Hydroxypropyltrimonium amylopectin / glycerol crosspolymer hydroxypropyltrimonium gelatin, hydroxypropyltrimonium honey, hydroxypropyltrimonium hydrolyzed casein,
  • hydrolysed vegetable protein hydroxypropyltrimonium hydrolysed wheat protein
  • Isostearamidopropylmorpholine oxide isostearamidopropyl PG-dimonium chloride, isostearamidopropylamine oxide,
  • Isostearaminopropalkonium chloride isostearoyl hydrolyzed collagen, isostearoyl PG-trimonium chloride, isostearyl benzoate, isostearylethyldimonium chloride,
  • Lauroamphodipropionic Acid Lauroyl Collagen Amino Acids, Lauroyl Hydrolysed Collagen, Lauroyl Hydrolysed Elastin, Lauroyl Lysine, Lauroyl PG Trimonium Chloride, Lauroyl Sarkosin, Laurotrimium Bromide, Laurylaminopropyl Glycine, Lauryl Betaine, Lauryl Diethylenediaminoglycine,
  • Linoleamide MEA Linoleamide MIPA
  • Linolenic acid Linolenic acid, lupinus albus oil, luteum ovi extract, lysine, lysine aspartate, magnesium nitrate, magnesium sulfate, maltodextrin, marmota oil, MEA-hydrolyzed collagen, MEA-hydrolyzed silk, ethionine, methylaspartic acid, methylglutamic acid,
  • Methylsilanolacetyl methionate milk amino acids
  • Nerzamidopropylamine oxide Mustela wax, Mustela oil, Myrica cerifera extract, Myrica cerifera leaf extract, yristamidopropylbetaine, myristamidopropylamine oxide, myristic amine oxide, myristaminopropionic acid,
  • Myristoylglutamic acid myristoyl hydrolyzed collagen, yristoylsarcosine, myristyl betaine,
  • Octyldodecyl lanolate Octyldodecyl lanolate, octyldodecyltrimonium oxide, olea europaea extract, olealconium chloride, oleamidopropyl betaine,
  • Oleamidopropyldimethylamine glycolate oleamidopropyldimethylamine hydrolyzed collagen
  • oleamidopropyldimethylamine lactate oleamidopropyldimethylamine propionate
  • Oleoyl sarcosine oleyl betaine, oleyl epoxypropyldimonium chloride, oleyl hydroxyethyl imidazoline, olivamidopropyl betaine,
  • Olivamidopropyldimethylamine lactate Oli amidopropylamine oxide, Oryza sativa wax, Oryza sativa extract, Ovum, oxidized keratin, palm kernamidopropyl betaine, palmamidopropyl betaine, palmitamidopropyl betaine, palmitamidopropyl amine oxide,
  • Palmitamine Oxide Palmitoylglycine, Palmitoylbenzene Amino Acids, Palmitoyl PG Trimonium Chloride, Palmitoyl Quinoa Amino Acids, Palmitoyl Silk Amino Acids, Panax Ginseng Extract, Pancreatin, Pantethine, Panthenol, Panthenyl Ethyl Ether,
  • Sesamidopropylbetaine sesamidopropylbetaindimetylamine
  • hydrolyzed wheat protein soluble collagen, soluble proteoglycan, soya hydroxyethyl imidazoline, soya amido ethyl dimonium / trimonium hydroxypropyl hydrolyzed wheat protein, soy amidopropyl betaine, soybean ethyldimonium ethosulfate, soya trimonium chloride, squalane,
  • Triticum vulgare germ protein Triticum vulgare gluten
  • Triundecanoin Triticum vulgare gluten
  • Triundecanoin Triticum vulgare gluten
  • Tyrosine Triundecanoin
  • undecylenamide DEA Triticum vulgare germ protein
  • Undecaylenamidopropyltrimonium methosulphate Udecylenoyl hydrolyzed collagen, undecylenoylxanthan, urea-D-glucuronic acid, Urtica dioica, Urtica dioica extract, valine, wheat germ amidopropyl betaine, wheat germ amidopropyldimethylamine hydrolyzed collagen, wheat germ amidopropyldimethylamine hydrolyzed wheat protein,
  • the group of smoothing agents comprises in particular
  • Boswelia carterii extract Boswelia serrata extract, Centella asiatica extract, Cetraria islandica extract,
  • the group of anti-dandruff active ingredients includes in particular Achillea millefolium extract, Achillea millefolium oil,
  • Quillaia saponaria extract Salcia officinalis extract, selenium sulfide, sodium slate / slate sulfonate, sulfur, Symphytum officinale extract, hydrolyzed TEA-undecylenoyl collagen, undecylenamide dea, undecyleneth-6 and urtica dioica extract.
  • the group of tanning agents includes in particular acetyl tyrosine and dihydroxyacetone.
  • the group of deodorizing agents includes, in particular, Abies pectinata extract, aluminum bromohydrate, aluminum chloride, aluminum chlorohydrate / dialuminium chloride pentoxide,
  • Aluminum zirconium octachlorohydrex GLY (Complex reaction products from the reaction of aluminum zirconium octachlorohydrate (Al8Zr (OH) 20C18.XH2O) with glycine),
  • Aluminum zirconium pentachlorohydrate GLY (Complex reaction products from the reaction of aluminum zirconium
  • zirconium trichlorohydrate aluminum zirconium trichlorohydrex GLY, ammonium phenolsulfonate, benzalkonium cetyl phosphate,
  • Cetylpyridinium chloride chlorothymol, cinnamomum zeylanicum extract, cloflucarban, dequalinium acetate, dequalinium chloride, dichloro-m-xylenol, butlorophen, domiphenbromide, eucalyptus globulus extract, farnesol, Juniperus communis extract, ketoglutaric acid, lauryl isoquinolinium bromide,
  • the group of depilatory agents includes, in particular, ammonium thioglycolate, ammonium thiolactate, barium sulfide, calcium sulfide, calcium thioglycolate, ethanolate thioglycolate, ethyl thioglycolate, lithium sulfide, magnesium sulfide, magnesium thioglycolate, mercaptopropionic acid, potassium sulfide, potassium thioglycolate, sodium sulfide , Sodium thioglycolate, strontium sulfide, strontium thioglycolate,
  • the group of emollients include, in particular, acetamidoethoxybutyl, trimonium chloride, acetyl
  • Glyceryl ricinoleate acetyl triethylhexyl citrate, acetylated castor oil, acetylated cetyl hydroxyproline, acetylated hydrogenated cotton glyceride, acetylated hydrogenated lanolin, acetylated hydrogenated (porcine) lard glyceride,
  • Amodimethicone / Dimethicone Copolyol Amp Isostearoyl Collagen (hydrolyzed), Anacardium Occidental Extract, Anacardium Occidental Nut Oil, Apricot Kernel Oil PEG-6 Ester,
  • Arachidonic acid Arachidyl alcohol, Arachidyl behenate,
  • Arachidyl Glycol Isostearate Arachidyl Propionate, Arachis Hypogaea Oil, Arctium Lappa Seed Oil, Argemone Mexicana Oil, Argan ginine-hexyldecyl phosphate, Arnica montana, Arnica montana extract, Asimina triloba extract, Avena sativa extract,
  • Behenyl alcohol behenyl behenate, behenyl benzonate, behenyl erucate, behenyl isostearate, behenyl / isostearyl beeswax, benzyl laurate, bis-diglyceryl polyacryladipate-1 & -2,
  • Brassica Campestris Papa Extract Brassica Oleracea Botryti Oil (unsaponifiable), Brevoortia Oil, Bubulura Oil, Betyl Acetyl
  • Glycol montanate Butyloctyl beeswax, Butyloctyl benzonate, Butyloctyl oleate, Butyrospermum Parkii butter, Butyrospermum Parkii butter extract, Butyrospermum Parkii butter
  • Acid triglyceride C12-20 isoparaffin, C13-13 isoparaffin, C14-18 glycol, C15-18 glycol, C18-28 alkyl acetate, C18-30 glycol, C18-36 acid glycol ester, C18-36 acid triglyceride, C18-38 alkyl beeswax, C18 -38 Alkyl Hydroxystearoyl Stearate, C18-70 Isoparaffin, C20-30 Glycol, C20-30 Glycol Isostearate, C20-40 Alkyl Behenate, C20-40 Isoparaffin, C24-28 Alkyl Methicone, C30-45 Alkyl Methicone, Calendula Officinalis, Calendula Officinalis Extract, Calendula Officinalis Oil, Calophyllum Tacamahaca Oil, Camelia Oleifera Seed Oil, Camelina Sativa Oil, Cananga Odorata Extract, Candelilla Cera, Canola
  • Triglyceride Triglyceride, Caprylyl Glycol, Carthamus Tinctorius Extract, Carthamus Tinctorius Oil, Carum Carvi Seed Oil, Castor Oil Benzoate, Cera Alba, Cera Carnauba, Ceratonia Siliqua Extract, Ceratonia Siliqua Gum, Cetearyl Alcohol, Cetearyl Behenate, Cetearyl Candelillate, Cetearyl Ethyl Hexanoate, Cetearyl Isononanoate, Cetearyl Palmitate, Cetraria Islandica Extract, Cetyl Acetate, Cetyl Acetyl Ricinoleate, Cetyl Alcohol, Cetyl C12-15 Paret-9 Carboxylate, Cetyl Caprylate, Cetyl Dimethicone, Cetyl Ester, Cetyl Ethyl Hexanoate, Cetyl Glyceryl Ethers,
  • Cetylricinoleate Cetyl Stearate, Cetylarachidol, Chaenomeles Japonica Extract, Chamomilla Recutita Extract, Cahmimilla
  • Cyclotetrasiloxane Cyclotrisiloxane, Dalea Spinosa Oil, DATEM, Daucus Carota, Daucus Carota Extract, Daucus Carota Juice, Daucus Carota Seed Extract, Decyl Alcohol, Decyl Isostearate, Decyl myristate, decyl oleate, decyl succinate, decyl tetradecanol, dibutyl adipate, dibutyl sebacate, di-C14-15 alkyl tartrate, di-C12-13 alkyl malate, di-C12-13 alkyl tartrate, di-C12-15 alkyl adipate, di-C12-15 alkyl futnarate, dicapryl adipate, dicapryl maleate , Dicetyl adipate, decetyl ether, dococamine, dococodimet ylamiii
  • Dilinoleate dicocoyl pentaerythrityl distearyl citrate, didecene, diethyl palmitoyl aspartate, diethyl sebacate, diethyl succinate, diethylene glycol dibenzoate, diethylene glycol
  • Copolyol -Dhupa butterate dimethicone copolyol hydroxystearate, dimethicone copolyol isostearate, dimethicone copolyl coco butter, dimethicone copolyol laurate, dimethicone copolyol mango butterate, dimethicone copolyol Moh a butterate,
  • Dimethyl lauramine isostearate dimethyl maleate, dimethyl succinate, dimethyl tallowamine, dioctyl dodeceth-2-lauroyl glutamate, dioctyl dodecyl adipate, dioctyl dodecyl dimer dilinoleate, dioctyl dodecyl dodecane dioioate, dioctyl dodecyl lauroyl glutamate, dioctyl dodecyl stearoyl Glutamate, Dioscorea Villosa Extract, Dipentaerythrityl Hexaheptanoate / Hexacaprylate / Hexaca Rat, Diphenyl Dimethicone, Dipropyl Adipate, Dipropylene Glycol Caprylate, Dipropylene Glycol Dibenzoate, Disteareth-2-Lauroyl Glutarate, Disteareth-5-Lauroyl Glutamate
  • Ethyl Palmitate Ethyl Pelargonate, Ethyl Persate, Ethyl Stearate, Ethylhexyl Acetoxystearate, Ethylhexyl Benzoate, Ethylhexyl Caprylate / Caprate, Ethylhexyl Cocoate, Ethylhexyl Ethyl Hexanoate, Ethylhexyl Glyceryl Palmitate, Ethylhexyl Hydroxystearate,
  • Vulgare Fruit Foeniculum Vulgare Oil, Fucus Vesiculosus Extract, Gadi lecur Oil, Gevuina Avellana Oil, Glycereth-5-Lactate, Glycereth-7-Diisononanoate, Glycereth-7-Triacetate, Glycereth-8-Hydroxystearate, Glycereth-20-Stearate, Glycerin / Oxybutylene copolymer stearyl ethe, glyceryl abietate, glyceryl adipate, glyceryl arachidate, glyceryl arachidonate, glyceryl behenate, glyceryl caprate, glyceryl caprylate, glyceryl caprylate / caprate, glyceryl cocoate, glyceryl diarachidate , Glyceryl dibehenate, glyceryl dierucate, glyceryl dihydroxy
  • Glyceryl stearate succinate glyceryl stearate / acetate, glyceryl stearate / maleate, glyceryl tallowate, glyceryl triacetyl hydroxystearate, glyceryl triacetyl ricinoleate,
  • Glyceryl / sorbitol oleate / hydroxystearate Glyceryl / sorbitol oleate / hydroxystearate, glycine soy extract, glycine soy flour, glycine soybean extract, glycine soybean oil,
  • Glycine soybean oil unsaponifiables glycine soy protein, glycine soybean sprout extract, glycine soy sterol, glycol cetearate, glycol dibehenate, glycol diethylhexanoate, glycol dilaurate, glycol Dioleate, glycol distearate, glycol ditallowate, glycol hydroxystearate, glycol oleate, glycol ricinolea, glycol stearate, glycol / butylene glycol ontanate, glycosaminoglycans, glycosphingolipids, glycyrrhiza glabra, glycirrhiza glabra extract, cottonseed oil, helianthus Annuus extract, Helianthus
  • Palm glycerides hydrogenated palm glyceride citrate, hydrogenated
  • Palm kernel glycerides hydrogenated palm kernel oil, hydrogenated palm oil, hydrogenated palm / palm kernel oil (PEG-6 ester), hydrogenated peanut oil, hydrogenated polydecene, hydrogenated polyisobutene, hydrogenated rapeseed oil, hydrogenated shark liver oil, hydrogenated
  • Soy glyceride hydrogenated soybean-derived glycerides, hydrogenated soybean oil, hydrogenated tallow, hydrogenated tallow acid, hydrogenated tallow alcohol, hydrogenated tallow glycerin, hydrogenated tallow glyceride Citrate, hydrogenated tallow glyceride lactate, hydrogenated tallow glycerides, hydrogenated tallow glyceride citrate, hydrogenated
  • Vegetable glyceride hydrogenated vegetable glyceride citrate, hydrogenated vegetable glyceride phosphate, hydrogenated vegetable oil,
  • Tinctoria oil isoamyl laurate, isobutyl myristate, isobutyl palmitate, isobutyl pelargonate, isobutyl stearate, isobutyl tallowate, isobutylated lanolin oil, isocetyl alcohol,
  • Isosteareth-10-stearate isostearyl alcohol, isostearyl avocadate, isostearyl behenate, isostearyl benzoate, isostearyl erucate, isostearyl ethyl hexanoate, isostearyl glyceryl pentaerythrityl ethe, isostearyl isononanoate, isostearyl Isostearate, isostearyl lactate, isostearyl laurate, isostearyl myristate, isostearyl neopentanoate, isostearyl palmitate,
  • Lactis Lipida Laneth 9-Acetate, Laneth-10 Acetate, Lanolin, Lanolin Acid, Lanolin Alcohol, Lanolin Cera, Lanolin linolea, lanolin oil, lanolin ricinoleate, lanosterol, pork fat glycerides, laureth-2-acetate, laureth-2-benzoate, laureth-2-ethylhexanoate, lauric / palmitic / oleic triglyceride, lauryl alcohol, lauryl behenate, lauryl cocoate, lauryl Ethylhexanoate, laurylglycol, lauryl isostearate, lauryl lactate, lauryl myristate, lauryl oleate, lauryl
  • Laurylmethicone Copolyol Lavandula Hybrida Extract, Lavandula Hybrida Oil, Lecithin, Lens Esculenta Extract, Lesquerella Fendleri Oil, Liliura Candidum Extract, Limnanthes Alba Seed Oil, Linoleic Acid, Linolenic Acid, Linoleyl Lactate, Linseed Acid, Linnum Usitatissiraum Extract, Linura Usitatissiraum Oil, Lupinus Al - bus oil, Lupinus Albus oil (unsaponifiable), Macadamia ternifolia extract, Macadamia ternifolia seed oil, maleated soybean oil, Malva Sylvestris extract, Malva Sylvestris leaf powder,
  • Mangifera Indica Seed Oil Mang Seed Oil PEG-70 Ester, Honey, Melia Azadirachta Seed Oil, Methicon, Methyl Acetyl Ricinoleate, Methyl Caproate, Methyl Caprylate, Methyl Caprylate / Caprate, Methyl Cocoate, Methyl Dehydroabietate, Methyl Gluceth-20-benzoate, methylglucose dioleate, methylglucose laurate, methyl glucose sesquicaprylate / sesquicapra, methyl glucose sesquicocoate, methyl glucose sesquiisostearate, ethyl glucose sesquilaurate, methyl glucose sesquioleate, methyl glucose sesquistearate, methyl hydroxystearate, methyl laurate, Methyllxnoleate, methyl myristate, methyl oleate, methyl palmitate, methyl palmitate, methyl pelargonate, methylricin
  • Octyldodecanol octyldodecyl behenate, octyldodecyl benzoate, octyldodecyl erucate, octyldodecyl ethylhexanoate, octyldodecyl lactate, octyldodecyl myristate, octyldodecyl neodecanoate, octyldodecyl neopentanoate, octyldodecyl oleate, octyldodecyl ricinoleate, octyldodecyl stearate, octyldodecyl stearoyl
  • Omentumlipide Orbignya Oleifera oil, Oryza Sativa bran oil, Oryza Sativa germ oil, egg cell oil, ozonized jojoba oil,
  • Palm glyceride palm glycerides, palm kernel acid, palm kernel alcohol, palm kernel glycerides, palmitic acid, palmitoyl collagen
  • Pantethine Papaver Oriental Oil, Papaver Rhoea Extract, Paraffin, Paraffinum Liquidum, Parietaria Officinalis Extract,
  • Pellis lipid penatdecyl alcohol, Pentadesma-butyracea butter, pentadoxynol-200, pentaerythrityl dioleate, pentaerythrityl isostearate / caprate / caprylate / adipate, pentaerythrityl stearate, pentaerythrityl stearate / caprate / caprylate / adipate,
  • Pentaerythrityl tetraabietate pentaerythrityl tetraacetate, pentaerythrityl tetrabehenate, pentaerythrityl tetrabenzoate, pentaerythrityl tetracapylate / caprate, pentaerythrityl tetracocoate pentaerythrityl tetraethylhexanoate,
  • Pentaerythrityl tetraisononanoate pentaerythrityl tetraisostearate, pentaerythrityl tetralaurate, pentaerythrityl tetramyristate, pentaerythrityl tetraoleate, pentaerythrityl tetrapelargonate, pentaerythrityl tetrastearate,
  • Pentaerythrityl trioleate pentahydrosis
  • Perfluoropolyraethyl isopropyl ether Persea Gratissima Cera, Persea Gratissima Extract, Persea Gratissima Oil, Persea Gratissima Oil (unsaponifiable), Vaseline, Phaseolus Lunatus Extract, Phenetyl Dimethicone, Phenyl Dimethicone, Phenylmethicone, Phenyltriraethicone, Phoenix Dactylifera Extract, Phosphatidylcholine, Piraenta Acris Oil, Pinus Pinaster Extract, Pinus
  • Strobus extract Piscum lecur oil, Pistacia vera seed oil, plant lipids, pollen extract, polyglyceryl-3-dicocoat,
  • Pentaricinoleate Polygonum Aviculare Extract, Polyisoprene, Polymethylsilsesquioxane, Polypentene, Polyquaternium-2,
  • PPG-2 - isostearate PPG-2-lanolin alcohol ether
  • PPG-2-myristyl ether propionate PPG-2-buteth-2
  • PPG-2-ceteth-1 PPG-2-ceteth-5
  • PPG- 3-Castor oil hydrogenated
  • PPG-3-myristyl ether PPG-3-deceth-2-carboxylic acid
  • PPG-3-isodeceth-1 PPG-4-jojaric acid
  • PPG-4-jojobalcohol PPG- - Laureth -2
  • PPG-4-laureth-7 PPG-4 lauryl ether
  • PPG-4 myristyl ether PPG-4 trideceth-6
  • PPG-4-buteth PPG-4 - ceteth-20
  • PPG-4 Deceth-4 PPG-5-lanolate
  • PPG-5-lanoli alcohol ether PPG-5-lanolin wax
  • PPG-5-lanolin wax glyceride PPG-5-
  • Lycopersicum oil sorbitan distearate, sorbityl-silanediol, soy acid, so a-palmitate, sphingolipids, spinal lipid extract, squalane, squalene, squalic acid l, stearoxy-dimethicone,
  • Stearoxymethicone / Dimethicone Copolymer Stearoxytrimethylsilane, Stearoyl Inulin, Stearyl Acetate, Stearyl Alcohol, Stearyl Bee Wax, Stearyl Behenate, Stearyl Benzoate, Stearyl Caprylate, Stearyl Citrate, Stearyl Dimethicone, Stearyl Erucate, Stearyl Ethyl Hexanoate, Stearyl glycol, stearyl glycol isosteara,
  • Tetrhydrofurfuryl-ricinoleate tetramethyl-tetraphenyl-trisiloxane, Theobroma cacao butter, Thunnus extract, Torreya califonica extract, triarachidine, tribehenin, tri-C12-13-alkylcitrate, tri-C14-15-alkylcitrate, tricaprin, tricaprylin, tricaprylyl- Citrate, trichloroethane, tridecyl alcohol,
  • Triisocetyl-citra Triisononanoin, triisopalmitin,
  • Triisopropyl citrate Triisopropyl citrate, triisopropyl trilinoleate, triisostearin, triisostearone PEG-6 ester, triisostearyl citrate,
  • Triisostearyl trilinoleate trilaurin, trilauryl citrate,
  • Trilinoleic acid Trilinolein, trilinolenin, trimethyl-pentaphenyl-trisoloxane, trimethylolpropane tricaprylate / tricapra, trimethylolpropane tricocoate,
  • Vulgare Germ Protein Triticum Vulgare Protein, Triundecanoin, Tussilago Farfara Extract, Tussilago Farfara Leaf Extract, Undecylenoyl Inulin, undecylpentadecanol,
  • Vegetable Glyceride Phosphate Verbena Officinalis Extract, Viola Tricolor Extract, Vitis Vinifera Seed Oil, Wheat Germinic Acid, Wheat Germ Glycerides, Ximenia Americana Oil, Maize Extract,
  • Corn oil corn gluten protein, corn oil and corn oil
  • the group of moisturizing agents includes, in particular, acetamide Mea, algae, aluminum hydroxide, arachidyl glycol, argilla, arginine PCA, bambusa vulgaris extract, benzyl hyaluronate, butoxypropanol, butylene glycol, butyloctanol, Calcium gluconate, caprylyl glycol, carboxymethyl chitosan succinamide, chitosa PCA, copper acetyl tyrosinate methylsilanol, copper PCA, copper PCA methylsilanol,
  • Glycereth-7 glycereth-12, glycereth-20, glycereth-26,
  • Glycereth-31 glycerol, glycogen, glycol, glycyrrhetinyl stearate, glycyrrhizic acid, hexacosylglycol, hexanediol beeswax, 1, 2, 6-hexanetriol, hexanetriol, hexanetriol beeswax, 3-hexenol, hexeth-4-carboxylic acid, hexyldecanol, Hexyldeceth-20, histidine, hyaluronic acid, hydrogenated honey, hydrogenated soybean oil, hydrogenated starch hydrolyzate, hydrogenated collagen, hydrogenated wheat starch, hydrogenated elastin, hydrogenated glycosarainoglycan, hydrogenated keratin, hydrogenated silk, hydrogenated soybean protein, hydrogenated wheat protein / dimethicone copolyolphosphine copolymer , Hydroxyethyl-palmityl
  • Methoxypropylgluconamide methyl behenate, methyl-gluceth-10, methyl-gluceth-20, methylglucose dioleate, methylsilanol PCA, nickel gluconate, PCA, PEG-2-lactamide, PEG-3-stearate, PEG-4, PEG-6, PEG-7, PEG-8, PEG-8 stearate, PEG-9, PEG-10, PEG-10 propylene glycol, PEG-12, PEG-14, PEG-16, PEG-18, PEG- 20, PEG-20 stearate, PEG-25, PEG-32, PEG-40, PEG-45, PEG-60, PEG-75, PEG-90, PEG-100, PEG-135, PEG-150, PEG- 180, PEG-200, PEG-240, phytantriol, placental protein, polyamino sugar condensate,
  • Polydextrose polyglucuronic acid, polyglycerol-3,
  • Trilactin Tritium Vulgare Gluten, Urea, Xylitol, Xylose, Corn Gluten Protein and Zinc PCA.
  • the group of moisturizing active ingredients include in particular Aloe Arborescens extract, Aloe Ferox extract,
  • Prunus serotina Prunus serotina bark extract, Prunus subtilis
  • Serotina Extract Quillaia Saponaria Extract, Red Vaseline, Ricinus Communis Oil, Saccharum Officinarum Extract, Saccharum Officinarum Powder, Salvia Hispanica Oil, Trehalose, Trilactin, Ulmus Fulva Bark and Ulmus Fulva Extract.
  • composition according to the invention contains as a cosmetic active ingredient a mixture of the active ingredients listed above, provided that this active substance mixture is compatible with one another.
  • Active substances which are present in the liquid composition according to the invention are generally to be stated that this concentration depends on the particular active substance or the respective active ingredients.
  • the active ingredient concentration varies between 0.005% by weight and 45% by weight, preferably in a concentration of between 0.01% by weight and 30% by weight.
  • the previously listed low drug concentrations are in particular present in the composition according to the invention, when the composition of the invention has only one or a few active ingredients.
  • this active ingredient combination is preferably present in the higher concentration ranges specified above.
  • composition according to the invention provides that in this case the composition contains as Phospholipidi Imageing agent isolated from soybeans phosphatidylcholine, in particular the concentration of this phosphatidylcholine in the phospholipid foaming more than 50 wt.%, Preferably between 50 wt.% And 95 wt .%, Based on the dry matter of the phospholipid foaming agent is.
  • Phospholipidi Imageing agent isolated from soybeans phosphatidylcholine, in particular the concentration of this phosphatidylcholine in the phospholipid foaming more than 50 wt.%, Preferably between 50 wt.% And 95 wt .%, Based on the dry matter of the phospholipid foaming agent is.
  • this phospholipid foaming agent contains at most 15% by weight of lyso-phosphatidylcholine, at most 10% by weight of phosphatidic acid and at most 10% by weight of phosphatidylethanolamine, it is possible with the aid of this special foaming agent to produce a foam which, by varying its concentration varied adaptable to the particular requirements of the application site.
  • the underlying the foam liquid composition is particularly long lasting, without that it requires an increased concentration of antioxidants or stabilizers, especially for the phospholipid foaming agent described above.
  • the concentration of the phospholipid foaming agent contained in the liquid composition is selected so that the foams listed at the start in the process according to the invention and the composition of the invention and specified by the foam volume and the foam stability can be produced .
  • the liquid composition which is foamed purely mechanically, preferably has the phospholipid foaming agent in a concentration between 0.5% by weight and 15% by weight, in particular in a concentration between 2% by weight and 8% by weight, on.
  • a further, very suitable embodiment of the composition according to the invention provides that the composition according to the invention contains as foaming agent a mixture of one or more phospholipid foaming agents or foaming agents and one or more surfactants or surfactants.
  • the mixture and in particular the previously mentioned two foaming agents can be ideally to the properties of the composition thus prepared and in particular their foaming behavior, ie in particular their foam volume and foam stability, to the particular desired requirements of the invention adjust the cosmetic composition.
  • the surfactants listed above are selected, whereby preferably in particular the ethers of sorbitan fatty acid esters with polyethylene glycol already described in detail above are used. be set.
  • the liquid composition which is foamed purely mechanically, the surfactant
  • Foaming agent in a concentration between 0.5 wt.% And 15 wt.%, In particular in a concentration between 2 wt.% And 8 wt. % , on .
  • composition according to the invention preferably containing, in addition to water, an alcohol and in particular propylene glycol whose concentration, depending on the desired and above-specified foam, is between 2% by weight and 20% by weight. %, in particular between 3% by weight and 10% by weight, varies.
  • the liquid composition according to the invention has a pH which is tolerated by the skin and, depending on the particular site of application, is between 4.8 and 8.8.
  • At least one buffer in particular sodium dihydrogen phosphate dihydrate and / or di-sodium hydrogen phosphate dodecahydrate, is added to the composition according to the invention.
  • composition according to the invention can be foamed with any suitable foam applicator, with particularly suitable applicators from Rexam / Airspray
  • the present invention thus also relates to a foam applicator which is filled with the composition according to the invention, as described in detail above.
  • each agitating blade is triangular in shape and has a height of 5 mm, so that each stirring surface accordingly forms a roof with a ridge angle of 90 °.
  • the stirring blades each consist of a conidur fine perforated plate ⁇ manufacturer: HeinLehmann, Krefeld) and have a sheet thickness of 0.5 mm, a perforation of 0.5 and a pitch of 3.2.
  • the sample volume was 250 ml, which was automatically taken by the meter to the reservoir, which was filled with at least 300 ml of sample.
  • the sample was carefully added to the storage container as far as possible while avoiding foaming. After a waiting time of ten minutes, so that any air bubbles formed during filling could migrate to the surface and thus did not adulterate the volume, 250 ml of the sample to be examined each were drawn into the measuring space and measured.
  • the respective samples to be examined in the measuring chamber were subjected to five rotor cycles of 20 seconds each for foam generation. Between the rotor cycles was a measurement break of about 15 seconds.
  • the control of the SITA-foam tester is such that after filling the measuring space with 250 ml sample, the needle detectors drive only to the surface of the sample and accordingly set the zero point for the foam volume on the surface of the sample and not on the bottom of the measuring space.
  • the needle detectors drive only to the surface of the sample and accordingly set the zero point for the foam volume on the surface of the sample and not on the bottom of the measuring space.
  • Volumnia reflects only the foam volume.
  • the temporal change of this foam volume is the foam stability.
  • composition according to Embodiment 1 has the following ingredients:
  • composition according to Embodiment 3 has the following ingredients:
  • composition according to Embodiment J has the following ingredients: Ingredient Composition in% by weight
  • a tea tree oil-containing composition was prepared according to the production method described above.
  • this composition according to Embodiment 5 has the following ingredients:
  • a tea tree oil-containing composition was prepared according to the production method described above.
  • this composition according to exemplary embodiment 6 had the following ingredients:
  • a tea tree oil-containing composition was prepared according to the production method described above.
  • this composition according to Embodiment 7 has the following ingredients:
  • this composition according to Embodiment 8 had the following ingredients:
  • N, 1- diethyl-m-toluamide-containing composition was prepared according to the manufacturing procedure described above.
  • this composition according to Embodiment 9 had the following ingredients:
  • N, N'-diethyl-m-toluamide-containing composition was prepared according to the production method described above.
  • this composition according to Embodiment 10 has the following ingredients:
  • this composition according to Embodiment 11 has the following ingredients: Ingredient Composition in% by weight
  • a spermidine 3 HCl-containing composition was prepared according to the preparation process described above.
  • this composition according to embodiment 12 has the following ingredients:
  • a spermidine 3 HCl-containing composition was prepared according to the preparation process described above.
  • this composition according to Embodiment 13 has the following ingredients:
  • a spermidine 3 HCl-containing composition was prepared according to the preparation process described above.
  • this composition according to embodiment 14 has the following ingredients:
  • a spermidine 3 HCl-containing composition was prepared according to the preparation process described above.
  • this composition according to embodiment 15 has the following ingredients:
  • a dexpanthenol ⁇ 50%, concentrate) -containing composition was prepared according to the manufacturing method described above.
  • this composition according to Embodiment 16 has the following ingredients:
  • a dexpanthenol (50%, concentrate) -containing composition was prepared according to the manufacturing process described above.
  • this composition according to Embodiment 17 has the following ingredients:
  • a dexpanthenol (50%, concentrate) -containing composition was prepared according to the manufacturing process described above.
  • this composition according to Embodiment 18 has the following ingredients: Ingredient Composition in% by weight
  • a dexpanthenol (50%, concentrate) -containing composition was prepared according to the manufacturing process described above.
  • this composition according to Embodiment 19 has the following ingredients:
  • a dexpanthenol (50%, concentrate) -containing composition was prepared according to the manufacturing process described above.
  • this composition according to embodiment 20 had the following ingredients:
  • a dexpanthenol ⁇ 50%, concentrate) -containing composition was prepared according to the manufacturing method described above.
  • this composition according to Embodiment 21 has the following ingredients:
  • a dexpanthenol (50%, concentrate) -containing composition was prepared according to the manufacturing process described above.
  • this composition according to Embodiment 22 has the following ingredients:
  • the phospholide foaming agent used has the following
  • composition wherein the following values relate to the dry matter of the foaming agent:
  • the above-mentioned peroxide value indicates the milliequivalents of oxygen contained in 1,000 g of a sample (dry substance). This value is determined after reaction of the sample with potassium iodide in a mixture of chloroform and acetic acid by titrimetrically determining the iodine produced in this way with sodium thiosulphate.
  • the acid number indicates how much mg of potassium hydroxide is required to contain the free, non-esterified fatty acids needed in 1 g of phospholipid foaming agent (dry matter). This value is determined by titrating a corresponding dissolved sample with potassium hydroxide solution using phenolphthalein as an indicator.
  • the subject study described below was performed, with each subject treated with three compositions.
  • the first composition was a foam prepared by the SITA feeding method according to Working Example 2
  • the second composition was a foam made with the "M3 mini- mizer" containing the ingredients of Exemplary Embodiment 2
  • the third composition tested was a commercial aloe vera -containing formulation.
  • the first and second test fields on the left and right of the spine were each treated with 10 mg aloe vera foam, produced by the SITA method according to Example 2, the third and fourth test fields on the left and right of the spine were each treated with 10 mg aloe. Vera foam, generated by the M M3
  • M3 mini foamer generated foam can be detected.
  • the average decrease was 39.3% and 38.2, respectively %.
  • the commercial formulation only achieved a decrease of 23.4% and was thus significantly worse.

Abstract

L'invention concerne un procédé pour développer une composition cosmétique liquide à appliquer sur la peau sous forme de mousse ainsi qu'une composition correspondante que l'on peut faire mousser et qui présente au moins un solvant, au moins un actif cosmétique ainsi qu'au moins un agent moussant. Le volume de la mousse et la stabilité de la mousse sont déterminés selon un procédé de mesure SITA normalisé. On fait varier la nature chimique et/ou la concentration de l'agent moussant, du solvant et de l'actif cosmétique jusqu'à ce que la mousse ainsi produite par le procédé de mesure SITA présente un volume d'au moins 400 ml et ait une stabilité telle que la mousse ait encore, après un temps de pose allant jusqu'à dix minutes, 50 % du volume qui était présent au départ immédiatement après la production de la mousse.
EP11801553.6A 2010-12-20 2011-07-07 Procédé pour développer une composition liquide à appliquer sur la peau sous forme de mousse ainsi que composition applicable topiquement Withdrawn EP2654665A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE201010055252 DE102010055252A1 (de) 2010-12-20 2010-12-20 Verfahren zur Entwicklung einer als Schaum auf die Haut zu applizierende flüssige Zusammensetzung sowie eine topisch applizierbare Zusammensetzung
PCT/DE2011/001416 WO2012083906A2 (fr) 2010-12-20 2011-07-07 Procédé pour développer une composition liquide à appliquer sur la peau sous forme de mousse ainsi que composition applicable topiquement

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EP2654665A2 true EP2654665A2 (fr) 2013-10-30

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EP11801553.6A Withdrawn EP2654665A2 (fr) 2010-12-20 2011-07-07 Procédé pour développer une composition liquide à appliquer sur la peau sous forme de mousse ainsi que composition applicable topiquement

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EP (1) EP2654665A2 (fr)
DE (1) DE102010055252A1 (fr)
WO (1) WO2012083906A2 (fr)

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EP2722075B1 (fr) * 2012-10-22 2018-02-28 BASF Beauty Care Solutions France S.A.S. Prévention de conditions de peau sèche et apaisement pour peaux sensibles
US20220296492A1 (en) 2019-08-06 2022-09-22 Natura Cosméticos S.A. Topical cosmetic composition, use of the composition and serum for applying on the face
CN110772457B (zh) * 2019-11-06 2022-05-10 广东科盈科技有限公司 一种防脱洗发水及其制备方法
WO2022051163A1 (fr) * 2020-09-01 2022-03-10 Ocean View Holdings, Llc (Dba Dew Mighty) Produit cosmétique solide
CN113332219B (zh) * 2021-06-11 2022-12-13 科丝美诗(中国)化妆品有限公司 一种调节皮肤内稳态平衡的化妆品组合物及其应用
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Also Published As

Publication number Publication date
WO2012083906A3 (fr) 2013-02-28
WO2012083906A2 (fr) 2012-06-28
DE102010055252A1 (de) 2012-06-21

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