EP2579992A1 - Produktspender mit einer pumpe und einem ausgabeendstück - Google Patents

Produktspender mit einer pumpe und einem ausgabeendstück

Info

Publication number
EP2579992A1
EP2579992A1 EP11735472.0A EP11735472A EP2579992A1 EP 2579992 A1 EP2579992 A1 EP 2579992A1 EP 11735472 A EP11735472 A EP 11735472A EP 2579992 A1 EP2579992 A1 EP 2579992A1
Authority
EP
European Patent Office
Prior art keywords
pump
neck
retaining
dispensing
reservoir
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP11735472.0A
Other languages
English (en)
French (fr)
Other versions
EP2579992B1 (de
Inventor
Xavier Donnette
José Camba
Philippe Sahm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nemera la Verpilliere SAS
Original Assignee
Rexam Healthcare La Verpilliere SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rexam Healthcare La Verpilliere SAS filed Critical Rexam Healthcare La Verpilliere SAS
Publication of EP2579992A1 publication Critical patent/EP2579992A1/de
Application granted granted Critical
Publication of EP2579992B1 publication Critical patent/EP2579992B1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005Components or details
    • B05B11/0008Sealing or attachment arrangements between sprayer and container
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005Components or details
    • B05B11/0062Outlet valves actuated by the pressure of the fluid to be sprayed
    • B05B11/0075Two outlet valves being placed in a delivery conduit, one downstream the other
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1001Piston pumps
    • B05B11/1004Piston pumps comprising a movable cylinder and a stationary piston
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042Components or details
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042Components or details
    • B05B11/1043Sealing or attachment arrangements between pump and container
    • B05B11/1049Attachment arrangements comprising a deformable or resilient ferrule clamped or locked onto the neck of the container by displacing, e.g. sliding, a sleeve surrounding the ferrule
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042Components or details
    • B05B11/1066Pump inlet valves
    • B05B11/1067Pump inlet valves actuated by pressure
    • B05B11/1069Pump inlet valves actuated by pressure the valve being made of a resiliently deformable material or being urged in a closed position by a spring
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005Components or details
    • B05B11/0027Means for neutralising the actuation of the sprayer ; Means for preventing access to the sprayer actuation means
    • B05B11/0032Manually actuated means located downstream the discharge nozzle for closing or covering it, e.g. shutters
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/0005Components or details
    • B05B11/0062Outlet valves actuated by the pressure of the fluid to be sprayed
    • B05B11/0064Lift valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B05SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05BSPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
    • B05B11/00Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
    • B05B11/01Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use characterised by the means producing the flow
    • B05B11/10Pump arrangements for transferring the contents from the container to a pump chamber by a sucking effect and forcing the contents out through the dispensing nozzle
    • B05B11/1042Components or details
    • B05B11/1052Actuation means

Definitions

  • Product dispensing device comprising a pump and a dispensing nozzle
  • the present invention relates to a product dispensing device attached to the neck of a tank.
  • a drug delivery device in the form of a spray comprising a pump, such as a nasal spray device.
  • a dispensing device ensures the greatest possible seal (to liquids, gases, bacteria) between the outside and the inside of the device or reservoir, that is to say all along the path traveled by the product, to prevent bacteria from developing and contaminate the product.
  • Such devices are often referred to as "preservative free” devices. They may be provided with a dispensing nozzle attached to the pump, comprising a non-return valve disposed just before the dispensing orifice of the product and preventing bacteria from developing in the dispensing tip. Such a tip is for example described in the publication FR 2887232.
  • the present invention is intended in particular to provide a dispensing device in which the risk of developing bacteria is even more reduced.
  • the subject of the invention is a product dispensing device, to be carried on the neck of a reservoir, characterized in that it comprises:
  • a pump comprising a metering chamber
  • a dispensing nozzle attached to the pump comprising a bearing surface for activating the device by a user
  • a device fixing member on the neck of the reservoir comprising means for fastening the member around the neck, activatable by sliding the collar relative to the fixing member from a predetermined configuration; assembly to an assembly configuration, an inner ring of
  • the device is attached to the tank by means of hooking means, which provide a snap-on shape activated by the clamp, and which constitute a method of fixing almost unmountable by the user, unlike a fastening by screwing.
  • This type of attachment is similar to a "snap-on" fixation.
  • the fastener also ensures retention of the dispensing nozzle on the device, thanks to its outer ring, which ensures that this nozzle can not be removed from the pump on which it is reported, even with a consequent force.
  • the dispensing nozzle is thus retained in two distinct ways on the device: on the one hand it is fixed on the pump, being attached to a movable part of the pump, for example by clamping, on the other hand it is retained by the outer ring of the nozzle, which thus prevents tearing of the nozzle attached to the pump.
  • the device proposed above can be assembled on the tank in one step, which is very advantageous.
  • the dispensing device is a module that carries all the distribution elements to report on the reservoir, in particular the pump, the dispensing tip and the protective cap. These elements thus form a module, pre-assembled thanks to the fastener.
  • the tank and the protective device it is only necessary to have the device in the pre-assembled position on the neck of the tank and to slide the clamping collar by simply pressing on the protective cover in order to activate the hooking means.
  • the hood being carried by the clamp, a support on the cover can be directly transmitted to the collar.
  • This assembly in one step is interesting because the inside of the dispensing device is protected by the cover and is therefore not in contact with the outside, which avoids any risk of contamination during final assembly.
  • This embodiment allows the dosing device to be manufactured in a different from the one in which it is assembled on the bottle without incurring the risk of particulate pollution.
  • the dosing chamber of the pump is preferably closed at the top by a first needle valve forming a non-return valve.
  • the dispensing tip optionally comprises a second needle, forming a non-return valve.
  • the dispensing device may further comprise one or more of the following features, taken alone or in combination.
  • the clamp comprises removable means for latching the cover, preferably in the form of an annular groove.
  • the inner ring centering of the pump comprises a reinforcing zone of an elastic tab to be passed in force for the product distribution.
  • an elastic tab can be used to constitute a hard point of activation, which ensures that the user exerts sufficient support on the device to ensure the distribution of a full dose of product, which is particularly important in the case of drugs.
  • the dispensing nozzle comprises a casing bearing on the one hand the bearing surface and on the other hand a retaining ring of the nozzle, slidably mounted relative to the outer ring of the fastener, preferably inside this ring, and cooperating by abutment with the retaining means carried by the fixing member.
  • the bearing surface is generally intended to be in contact with two fingers of the user.
  • the casing further comprises a housing for receiving a needle valve forming a non-return valve, closing the product dispensing orifice by elastic return exerted by a spring.
  • the dispensing tip comprises, in addition to the retaining ring of the tip, a base fixed on a moving part of the pump.
  • the base and the retaining ring are two distinct parts of the nozzle, the base being preferably attached to the inside of the casing and having a tubular part coming to fit on the movable part of the pump so that waterproof.
  • the tubular part of the base is at least partly inside the retaining ring, being coaxial with this ring.
  • the retaining means comprise a retaining lug, forming a stop for an annular rib formed on the retaining ring.
  • the retaining means may comprise a plurality of lugs.
  • An advantage of a continuous annular rib lies in the fact that it is not necessary to provide a particular angular disposition of the nozzle when it is mounted on the device.
  • the outer ring of the fixing member carries on its outer surface an upper stop for holding the clamp in its pre-assembly configuration of the device. This stop makes it possible to maintain the fixed collar on the member, before its assembly on the tank.
  • the fastening means of the member around the neck comprises a lower stop for holding the clamp in its preassembly configuration of the device.
  • This stop makes it possible to maintain the fixed collar relative to the member, before it is assembled on the reservoir, and can serve as a support for the clamping collar to deform deformable means when it slides.
  • the lower stop is carried by deformable means, for example elastic means.
  • the fastener is plastic, which is particularly appropriate in the medical field because it avoids generating harmful particles.
  • the clamp is configured so that a support on the cover is directly transmitted to the clamp, so that it moves from its pre-assembly configuration to its assembly configuration.
  • the clamping collar comprises a bearing support of the cover, preferably in the form of an outer collar projecting from a main wall of the collar.
  • the invention furthermore relates to an assembly of a tank and a device according to any one of the preceding claims, wherein the clamping collar can take on the neck of the tank a pre-assembled position and an assembled position.
  • the fastening means of the organ around the neck comprising deformable means, which are not deformed in the preassembled position and which are deformed in the assembled position, being kept deformed by the clamping collar.
  • the deformable means can be deformed in the preassembled position and not deformed in the assembled position, being held undeformed by the clamping collar.
  • the deformable means are elastic.
  • the subject of the invention is also a method for assembling such a dispensing device on a reservoir, during which the device is brought back onto the neck of the reservoir in a first position called pre-assembled. protection, which generates the sliding of the clamp so that the dispensing device takes a second position called assembly.
  • FIG. 1 is a schematic sectional view of a distribution device in the pre-assembled position on a reservoir
  • FIG. 2 is a diagrammatic sectional view of a dispensing device according to an alternative embodiment, in an assembled position on the reservoir,
  • FIG. 3 is an enlarged view of part of FIG. 1, and
  • FIG. 4 is a perspective view of a fastener of the devices of Figures 1 and 2.
  • a dispensing device 10 is attached to a reservoir 12, so as to deliver a product.
  • the product is liquid and is intended for nasal sprays of liquid pharmaceutical product.
  • the reservoir 12 has a neck 14 on which the device 10 can assume a pre-assembled position, illustrated in FIG. 1, and an assembled position, illustrated in FIG.
  • the device 10 comprises a pump 16, a dispensing nozzle 18, a protective cap 20, a clamp 22 and a fastener 24.
  • the pump 16 comprises a so-called fixed part and a so-called mobile part, sliding relative to one another, so as to eject the product stored in a dosing chamber 26 which defines a dosing volume, this product being dispensed during activation of the device.
  • the fixed part of the pump 16 comprises a pump body 28, receiving a tube 30 of the product and carrying a piston, sliding in the chamber 26.
  • the pump body is attached to the upper surface of the tank neck 14, a seal being interposed between the body 28 and the neck 14.
  • the piston comprises a support 32 and a membrane 34 forming a non-return valve.
  • the membrane forms a single piece with an elastomeric cylindrical skirt, bearing sliding sealing means in the chamber 26.
  • the piston comprises, in addition to the membrane, an element 36 for fixing the membrane. which is a separate part of the membrane and which comprises the cylindrical skirt and the sliding sealing means.
  • the fixed part of the pump 16 also comprises a sleeve 38, fixed in the pump body 28, for example by clamping, serving as a seat for a first spring 40.
  • the sleeve 38 has one or more elastic tabs 42 to be passed through. force for product distribution, constituting a hard point of activation.
  • the moving part of the pump 16 is also called the dispensing head.
  • the dispensing head further comprises a second cylinder 46, possibly made in one piece with the first cylinder 44.
  • a first needle valve 48 forming a non-return valve is slidably mounted inside the second cylinder 46, between a position resting and activated position, under the action of a second spring 50.
  • the needle 48 is provided with a base, mounted in a sealed manner in the second cylinder 46, a rod configured to be able to close, in the position of rest of the pump, an orifice formed on the lower end of the second cylinder 46, and an end projecting slightly inside the metering chamber 26 when the needle 48 is in the activated position.
  • the moving part of the pump 16 further comprises a support 52, or ejection tube, which comprises a tubular end 54, on which is fixed the dispensing nozzle 18.
  • the support 52 is provided with an inner skirt 56 and an outer skirt, between which the spring 40 is housed.
  • the moving part of the pump slides relative to the fixed part between a rest position and an activated position.
  • the support 52 further comprises means ensuring the passage of the liquid from the metering chamber 26 to the dispensing tip 18, arranged in particular between the second cylinder 46 and the inner skirt 56 of the support 52.
  • the dispensing nozzle 18 comprises a casing 60, inside which are attached a base 62, a cylinder 64 in which is housed a second needle valve 66 forming a non-return valve, under the action of a third spring 68 This non-return valve ensures that the spray nozzle is impervious to contaminants.
  • the envelope 60 comprises a support surface 70, in the form of two fins, for activation of the device by a user.
  • the casing 60 also comprises a ring 72 for retaining the end piece, by cooperation with the fixing member 24.
  • the ring 72 carries, at its lower end, a continuous annular rib 73.
  • the envelope 60 also comprises a spray end 74, provided with a spray orifice 76 closed by the needle 66 under the action of the spring 68.
  • the spray end 74 delimits, with the cylinder 64, a swirl chamber of distribution.
  • the base 62 is an insert inside the casing 60, for example by clamping, and comprising a tubular portion 78 fixed to the portion 54, for example by clamping around the portion 54.
  • the fixing member 24 is made of plastic. It comprises, on its upper part, an inner ring 80 for centering the pump 16 on the reservoir 12 and an outer ring 82.
  • the outer ring 82 carries, on its upper end, means 84 for retaining the dispensing nozzle. 18, cooperating by abutment with the casing 60.
  • the means 84 comprise one or more retaining lugs, forming a stop for the rib 73.
  • the outer ring 82 also bears on its outer surface an upper stop 83 for holding the collar 22. in its pre-assembly configuration of the device, as described below.
  • the inner ring 80 assures a positioning of the pump 16 on the fastening member 24.
  • the member 24 furthermore comprises a zone 86 for reinforcing the elastic tab 42, illustrated in FIG. 3, avoiding the plastic deformation of this paw.
  • the member 24 further comprises a lower skirt 87 carrying means 88 for hooking the member around the neck 14, which can be slidably actuated by the collar 22 relative to the fixing member from a pre-assembly configuration to a assembly configuration.
  • the attachment means 88 visible in FIG. 4, comprise elastic means which constitute a lower abutment 90 for holding the clamp 22 in its pre-assembly configuration, as illustrated in FIG. 1, and which are deformable from so that they can be forced through the collar and they can exert a restoring force on the collar 22 when in assembly configuration, visible in Figure 2. This restoring force pushes the means 88 against the collar 22 and thus ensures a maintenance of the collar 22 in the assembly configuration.
  • the fixing member 24 further includes lugs 89 for holding the member 24 in the pre-assembled position on the neck of the tank.
  • the clamp 22 is also made of plastic. It has a cylindrical shape so as to slide around the lower skirt 87 of the member 24.
  • the collar 22 comprises detachable means 92 for locking the cover 20, for example an annular groove 92, cooperating with an annular rib of the 20.
  • the collar 22 carries the cover 20 and is configured so that a bearing on the cover 20 is directly transmitted to the collar 22, so as to pass from its pre-assembly configuration to its assembly configuration. .
  • the collar 22 has a bearing surface 94 for supporting the cap 20, in the form of an external collar 94 projecting from the collar 22.
  • the device 10 is first assembled independently of the reservoir 12, for example in a first place, by assembling it in a pre-assembly configuration. More specifically, the fixing member 24 and the clamping collar 22 are reported around the pump body 28, then the fixed part of the pump 16 is assembled, by placing the piston, the tube 30 and the sleeve 38 on the body pump 28, as well as the movable portion of the pump, by bringing back on the fixed part the spring 40, the support 52 and the cylinders 44, 46 provided with the needle 48 and the spring 50. The dispensing nozzle 18 is then reported.
  • the device 10 is particularly advantageous if it is used with the product without preservative. Indeed, the retention of the nozzle 18 by the means 84 provides an additional guarantee that the tip will not be detached from the device following a fall or manipulation of the user. Furthermore, the user will not be able to disassemble the fastening means 88.
  • the device 10 is particularly indicated in an "airless" type system, without air intake. Indeed, this type of pump is used in the case where it is important that no bacteria is in contact with the product, and the device 10 is an effective device to prevent the introduction of bacteria.
  • the structure and operation of the device 10 are not limited to what is previously described.
  • dispensing device 10 could have the same functionality while being fixed differently on the neck of the tank.
  • the fastener could be fixed, not in the "snap-on" mode, but by crimping or screwing.
  • similar parts are used, except that the device does not comprise a clamp, the cover being attached directly to the outer ring of the fastener, and that the fastener comprises, the place of the elastic fastening means on the neck, fastening means by crimping or screwing.

Landscapes

  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Closures For Containers (AREA)
EP11735472.0A 2010-06-10 2011-06-09 Produktspender mit einer pumpe und einem ausgabeendstück Active EP2579992B1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1054608A FR2961192B1 (fr) 2010-06-10 2010-06-10 Dispositif de distribution de produit comprenant une pompe et un embout de distribution
PCT/FR2011/051318 WO2011154663A1 (fr) 2010-06-10 2011-06-09 Dispositif de distribution de produit comprenant une pompe et un embout de distribution

Publications (2)

Publication Number Publication Date
EP2579992A1 true EP2579992A1 (de) 2013-04-17
EP2579992B1 EP2579992B1 (de) 2019-10-30

Family

ID=43530390

Family Applications (1)

Application Number Title Priority Date Filing Date
EP11735472.0A Active EP2579992B1 (de) 2010-06-10 2011-06-09 Produktspender mit einer pumpe und einem ausgabeendstück

Country Status (5)

Country Link
US (1) US8863993B2 (de)
EP (1) EP2579992B1 (de)
CN (1) CN103025437B (de)
FR (1) FR2961192B1 (de)
WO (1) WO2011154663A1 (de)

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US20140263456A1 (en) * 2013-03-15 2014-09-18 Launce R. Barber Child-resistant closure systems for containers
US20140263457A1 (en) 2013-03-15 2014-09-18 Launce R. Barber Child-resistant closure systems for containers
US9950844B2 (en) 2013-03-15 2018-04-24 Taptango, Llc Child-resistant closure systems for containers
CN105435360A (zh) * 2014-12-12 2016-03-30 常熟大吉医用塑料制品有限公司 一种带鼻喷泵的塑料瓶
FR3063661B1 (fr) * 2017-03-07 2021-05-21 Promens Sa Dispositif de distribution d'un produit avec amorcage ameliore
CN111032117B (zh) 2017-08-30 2022-03-25 诺和诺德股份有限公司 具有防腐剂的流动连通单元
JP7345452B2 (ja) 2017-08-30 2023-09-15 ノボ・ノルデイスク・エー/エス より少ない防腐剤を有する薬剤のための複数回使用薬剤送達装置
JP7157750B2 (ja) * 2017-09-15 2022-10-20 株式会社新日本科学 薬剤保管用のノズル付きカートリッジとその噴射器、および鼻腔用粉状薬剤施薬装置
US10617832B2 (en) * 2017-11-22 2020-04-14 Southwest Research Institute High precision, low dose atomizer
JP6991332B2 (ja) * 2017-12-08 2022-01-12 エスゼット ディージェイアイ テクノロジー カンパニー リミテッド ノズルアセンブリ、ノズル装置、及び無人航空機
WO2019182745A1 (en) 2018-03-19 2019-09-26 Bryn Pharma, LLC Epinephrine spray formulations
CN109592203B (zh) * 2018-11-19 2020-02-14 深圳博纳精密给药系统股份有限公司 一种无菌喷雾泵

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Also Published As

Publication number Publication date
FR2961192B1 (fr) 2012-07-27
WO2011154663A1 (fr) 2011-12-15
FR2961192A1 (fr) 2011-12-16
EP2579992B1 (de) 2019-10-30
US8863993B2 (en) 2014-10-21
US20130175303A1 (en) 2013-07-11
CN103025437B (zh) 2015-11-25
CN103025437A (zh) 2013-04-03

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