EP2399682A1 - Cabine à flux laminaire pour laboratoires de recherche - Google Patents

Cabine à flux laminaire pour laboratoires de recherche Download PDF

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Publication number
EP2399682A1
EP2399682A1 EP11171150A EP11171150A EP2399682A1 EP 2399682 A1 EP2399682 A1 EP 2399682A1 EP 11171150 A EP11171150 A EP 11171150A EP 11171150 A EP11171150 A EP 11171150A EP 2399682 A1 EP2399682 A1 EP 2399682A1
Authority
EP
European Patent Office
Prior art keywords
operating plane
laminar flow
front panel
box portion
cabin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP11171150A
Other languages
German (de)
English (en)
Inventor
Giovanni Tartaglia
Andrea Mazzucchelli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tecniplast SpA
Original Assignee
Tecniplast SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tecniplast SpA filed Critical Tecniplast SpA
Publication of EP2399682A1 publication Critical patent/EP2399682A1/fr
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K1/00—Housing animals; Equipment therefor
    • A01K1/02—Pigsties; Dog-kennels; Rabbit-hutches or the like
    • A01K1/03—Housing for domestic or laboratory animals
    • A01K1/031—Cages for laboratory animals; Cages for measuring metabolism of animals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B08—CLEANING
    • B08B—CLEANING IN GENERAL; PREVENTION OF FOULING IN GENERAL
    • B08B15/00—Preventing escape of dirt or fumes from the area where they are produced; Collecting or removing dirt or fumes from that area
    • B08B15/02—Preventing escape of dirt or fumes from the area where they are produced; Collecting or removing dirt or fumes from that area using chambers or hoods covering the area
    • B08B15/023—Fume cabinets or cupboards, e.g. for laboratories

Definitions

  • the present invention relates to a cabin with laminar air flow that is particularly suitable for use in research laboratories that carry out animal experiments, and that require a working area with controlled contamination.
  • Cabins of this type provide forced control of the air flow with partial recirculation, with a reduced working opening at the front and front aspiration of ambient air (called protective or of containment) which, passing under the operating plane and through the top of the space, is subdivided into ideal unidirectional laminar flow lines, parallel to one another.
  • This solution provides notable cleanness of the flow, without turbulence, thus greatly reducing not only cross-contamination of the products manipulated within it but also dispersion of the infectious agents and therefore contamination of the environment and of the operator.
  • Laminar flow cabins thus perform multiple functions: protection of the animals from mutual and/or external contamination, protection of the operator and protection of the laboratory environment.
  • the operation most commonly carried out by the technician comprises cage changing, an operation in the course of which the animals are transferred from a dirty cage to a clean cage, and together with the animals, the technician transfers any cage accessories, for example a food trough and water bottles.
  • biological safety cabins of class I ensure protection from biological agents for the operator and for the working environment outside the cabin but not for the product being manipulated. Protection is provided by the flow of air entering through the open front section and filtration of all the air that is expelled on a HEPA filter prior to discharge to the environment.
  • the biological safety cabins of class II (which includes the cabin according to the present invention) as well as providing protection from biological agents for the operator and for the working environment outside the cabin, provide protection of the material being processed, in our case laboratory animals, from external contaminants.
  • the partial front opening permits ingress of air that is aspirated from the grid positioned at the bottom of the front opening and then, after passing through the HEPA filter, is introduced from above into the working chamber, creating a vertical laminar flow.
  • the amount of air aspirated is approximately 30% of the amount of air that generates the vertical laminar flow.
  • An amount of air equal to that which generated the protection (or containment) barrier is expelled from the top of the cabin through another HEPA filter.
  • the amount of air filtered and recirculated in the working zone in conditions of laminar or unidirectional flow is equal to 70%.
  • the biological safety cabins of class III are hermetically sealed cabins of the glove-box type, where the operator is physically separated from the product, with a HEPA filter on the ingoing air and double HEPA filters in series on the outgoing air. These cabins guarantee excellent protection of the environment and of the operator but poor protection with respect to the product.
  • the main aim of the present invention is therefore to provide a laminar flow booth or cabin that can easily be used in biohazard conditions, i.e. microbiological safety, or not, therefore both for execution of laboratory experimental procedures and typically for cage changing of the cages of animals in animal breeding departments, making it easy to introduce even bulkier cages in the cabin.
  • the purpose of the present invention is to provide a laminar flow cabin with microbiological safety level which is more convenient to use and more ergonomic for the user.
  • a laminar flow cabin of the type comprising an operating plane supported by a lower box portion and surmounted by a plenum or upper box portion, further comprising air intake means able to convey said laminar air flow under said operating plane, characterized in that said operating plane is movable in the vertical direction relative to said air intake means.
  • the laminar flow cabin according to the present invention is characterized in that said upper plenum comprises a protective transparent front panel, which is also movable in a substantially vertical direction between a completely raised position and a completely lowered position, passing through one or more intermediate positions.
  • the laminar flow cabin 1 according to the present invention comprises a lower box portion 2 which supports air intake means, constituted for example of the grid 2a, and an operating plane 4.
  • the lower box portion contains, as is known from the prior art, means for intake and conveyance of the laminar air flow, means for filtering the incoming air from grid 2a and similar devices, and is surmounted by an upper box portion 3 which holds similar means for movement and filtration of the air as known from the prior art, and further comprises a transparent front panel 5 preferably made of glass.
  • Said front panel 5 is connected to the front part of the upper box portion 3, and is movable between a completely lowered position and a completely raised position, passing through one or more intermediate positions, owing to means for moving the front panel, not shown in the drawings. These means for movement can be of the type known from the prior art.
  • the laminar flow cabin according to the present invention is provided with means 10 for moving the operating plane 4, said means comprising in particular, in the embodiment shown here as an example of a possible solution, a motorized system with a pantograph, illustrated in Fig. 8 , which allows vertical movement of said operating plane.
  • the operating plane 4 is movable between a first position, illustrated for example in Figs. 1 and 3 , in which the plane is lowered to produce a difference in level with the edge 2b of the lower box portion 2 on which the air intake grid 2a is installed.
  • the cabin according to the present invention comprises a central control unit, programmable and actuable by the operator, for coordinated movement of the operating plane 4 and the front panel 5.
  • the cabin according to the present invention can be used, in a first configuration, for the normal procedures of cage changing.
  • the operating plane 4 is lowered, by the movement means 10, by an amount of about 100-120 mm relative to air intake grid 2a and the front panel 5 is positioned in the intermediate position, corresponding to a situation in which the working front opening is at a height of 320 mm.
  • the operating plane 4 is, as mentioned, arranged at a lower level relative to edge 2b on which the air intake grid 2a is housed.
  • the difference in level of about 120 mm that is created between the operating plane and the edge of the lower box portion 2 makes both insertion and especially removal of cages of larger dimensions in and from cabin 1 difficult and tiring for the operator.
  • the cabin can easily be used in microbiological activities in compliance with European standard EN12469 giving fundamental safety and hygiene requirements for microbiological safety sites.
  • the operating plane 4 is raised until it is flush with the air intake grid 2a, while front panel 5 moves to a lowered position in which the front opening is of only 250 mm (as expressly stated in European directive EN12469).
  • the operator can move the opening of the front panel 5 bringing the panel into the completely open position in which the front aperture is of 450 mm, for example, without the operating plane 4, already flush with the edge of lower box portion, moving.
  • This configuration allows the operator to introduce cages easily into the laminar flow cabin. Once the cages or other bulky objects are inserted, the front panel 5 can be moved back to the completely lowered position in which the front opening is of 250 mm.
  • the laminar flow cabin according to the present invention through coordinated action, by means of a central control unit, of means for moving the front panel and of means for moving the operating plane, can easily be used both for cage changing (in particular, it proves ideal for those unwieldy cages) and for microbiological procedures (e.g. manipulation of pathogenic and non-pathogenic microorganisms, such as viruses, bacteria etc.).
  • the laminar flow cabin according to the present invention is more ergonomic for the operator in the phases of cage insertion and removal, in particular for those that are bulkier, guaranteeing in the operational phase, optimum protection of the product and, specifically, of the animal, of the operator and of the environment.

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Animal Husbandry (AREA)
  • General Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Housing For Livestock And Birds (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
EP11171150A 2010-06-25 2011-06-23 Cabine à flux laminaire pour laboratoires de recherche Withdrawn EP2399682A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT001157A ITMI20101157A1 (it) 2010-06-25 2010-06-25 Cappa a flusso laminare per laboratori di ricerca

Publications (1)

Publication Number Publication Date
EP2399682A1 true EP2399682A1 (fr) 2011-12-28

Family

ID=43568017

Family Applications (1)

Application Number Title Priority Date Filing Date
EP11171150A Withdrawn EP2399682A1 (fr) 2010-06-25 2011-06-23 Cabine à flux laminaire pour laboratoires de recherche

Country Status (2)

Country Link
EP (1) EP2399682A1 (fr)
IT (1) ITMI20101157A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3021562A1 (fr) * 2014-06-03 2015-12-04 Noroit Hotte notamment de change pour animaux
WO2017081572A1 (fr) * 2015-11-09 2017-05-18 Kivex Biotec A/S Station de travail à flux d'air laminaire à régulation de la température

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2567622A (en) * 1947-09-19 1951-09-11 Shell Dev Fume hood
GB2294395A (en) * 1994-10-26 1996-05-01 Robert Knight Ventilated enclosures
DE19549396A1 (de) * 1995-05-10 1997-01-09 Doerfert Hans Joachim Sicherheitswerkbank
DE10012594A1 (de) * 2000-03-15 2001-09-27 Analytik Jena Ag Laborabzug
US20030109211A1 (en) * 2001-12-11 2003-06-12 Bastian John M. Fume hood with rotatable airfoil
WO2003050453A1 (fr) * 2001-11-07 2003-06-19 Lab Products, Inc Station de travail dotee d'un dispositif de regulation du debit d'air
US20080150404A1 (en) * 2006-12-20 2008-06-26 Keiichi Ono Safety cabinet

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2567622A (en) * 1947-09-19 1951-09-11 Shell Dev Fume hood
GB2294395A (en) * 1994-10-26 1996-05-01 Robert Knight Ventilated enclosures
DE19549396A1 (de) * 1995-05-10 1997-01-09 Doerfert Hans Joachim Sicherheitswerkbank
DE10012594A1 (de) * 2000-03-15 2001-09-27 Analytik Jena Ag Laborabzug
WO2003050453A1 (fr) * 2001-11-07 2003-06-19 Lab Products, Inc Station de travail dotee d'un dispositif de regulation du debit d'air
US20030109211A1 (en) * 2001-12-11 2003-06-12 Bastian John M. Fume hood with rotatable airfoil
US20080150404A1 (en) * 2006-12-20 2008-06-26 Keiichi Ono Safety cabinet

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3021562A1 (fr) * 2014-06-03 2015-12-04 Noroit Hotte notamment de change pour animaux
WO2017081572A1 (fr) * 2015-11-09 2017-05-18 Kivex Biotec A/S Station de travail à flux d'air laminaire à régulation de la température
US11260385B2 (en) 2015-11-09 2022-03-01 Kivex Biotec A/S Laminar air flow workstation with temperature control

Also Published As

Publication number Publication date
ITMI20101157A1 (it) 2011-12-26

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