EP2323918B1 - Emballage à blister - Google Patents

Emballage à blister Download PDF

Info

Publication number
EP2323918B1
EP2323918B1 EP09781315A EP09781315A EP2323918B1 EP 2323918 B1 EP2323918 B1 EP 2323918B1 EP 09781315 A EP09781315 A EP 09781315A EP 09781315 A EP09781315 A EP 09781315A EP 2323918 B1 EP2323918 B1 EP 2323918B1
Authority
EP
European Patent Office
Prior art keywords
film
blister pack
containers
pack according
perforation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Not-in-force
Application number
EP09781315A
Other languages
German (de)
English (en)
Other versions
EP2323918A1 (fr
Inventor
Stephan Kurtze
Stefan Lustenberger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
Boehringer Ingelheim International GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International GmbH filed Critical Boehringer Ingelheim International GmbH
Priority to EP09781315A priority Critical patent/EP2323918B1/fr
Publication of EP2323918A1 publication Critical patent/EP2323918A1/fr
Application granted granted Critical
Publication of EP2323918B1 publication Critical patent/EP2323918B1/fr
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/03—Containers specially adapted for medical or pharmaceutical purposes for pills or tablets
    • A61J1/035—Blister-type containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D75/00—Packages comprising articles or materials partially or wholly enclosed in strips, sheets, blanks, tubes, or webs of flexible sheet material, e.g. in folded wrappers
    • B65D75/28—Articles or materials wholly enclosed in composite wrappers, i.e. wrappers formed by associating or interconnecting two or more sheets or blanks
    • B65D75/30—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
    • B65D75/32—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents
    • B65D75/325—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil
    • B65D75/327—Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding one or both sheets or blanks being recessed to accommodate contents one sheet being recessed, and the other being a flat not- rigid sheet, e.g. puncturable or peelable foil and forming several compartments
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2215/00—Child-proof means
    • B65D2215/02—Child-proof means requiring the combination of simultaneous actions

Definitions

  • the invention relates to a blister pack with a bottom foil and a cover sheet for forming a plurality of separable by perforations foil container, each having a receiving chamber for a product, in particular a pharmaceutical drug formulation, wherein the receiving chambers are arranged on the peripheral periphery of the blister.
  • the invention relates to a blister pack with a bottom foil and a cover foil for forming a plurality of separable by perforations foil container, each having a receiving chamber for a product, in particular a pharmaceutical drug formulation, the square-shaped foil containers are arranged in a matrix.
  • WO 2007 / 009127A discloses a blister pack according to the preambles of claims 1 and 6.
  • Film containers are used, inter alia, to protect pharmaceutical active ingredient formulations from environmental influences from the outside, which under certain circumstances may influence the pharmaceutical quality of the active substance formulation, and generally consist of a cover foil and a bottom foil, wherein cavities for the filling material are formed in the bottom foil.
  • the cover foil and the bottom foil can be made from one or multiple layers of different or the same materials.
  • the cover sheet is sealed to the bottom sheet, for example by gluing, welding or sealing.
  • the cover film and / or the bottom film are generally formed as metal and / or plastic and / or paper foil. These materials can be present in multiple layers.
  • Typical metal foils include, for example, aluminum foils and aluminum composite foils made of aluminum and, for example, a plastic.
  • plastic films may polyvinyl chloride (PVC) cycloolefin copolymer (COC), polychlorotrifluoroethylene (PCFE), polyethylene (PE), polypropylene (PP), polyethylene terephthalate (PET), polycarbonate (PC), polyester (UP), polyacrylate, polyamide (PA) or another plastic or a multilayer plastic composite film, for example consisting of a combination of polychlorotrifluoroethylene (PCTFE), which is known in particular under the trade name Aclar® protected for Honeywell International, Inc., with polyvinyl chloride (PVC) or polyvinyl chloride (PVC ) with polyvinylidene chloride (PVdC).
  • PCTFE polychlorotrifluoroethylene
  • PVdC polyvinylidene chloride
  • a film container or blister of a cover foil made of aluminum which closes the bottom foil for receiving the pharmaceutical product or active ingredient.
  • This deep-drawn bottom sheet may also comprise an aluminum foil to prevent the entry of water into the cavity for receiving the pharmaceutical product.
  • the aluminum foil of the bottom foil but also the cover foil can be covered on one or both sides with further plastic and / or paper foils.
  • the object is achieved in that the center of the blister pack is formed by a detachable film section, after its removal, an opening area for opening the receiving chamber is present.
  • perforation is understood to mean both an actual punching through of a material or a plurality of material layers or layers of the blister package as well as a material thinning, crease line, fold line, embossing mark or the like. Such perforations may be machined in the manufacture of the blister package to permit tearing or severing of individual film containers.
  • the film section is expediently associated with a perforation running around it in a circular manner.
  • the film containers can be separated segment by segment.
  • the perforation between the film containers does not extend to the outer periphery of the blister package.
  • an unintentional tearing or separation of the film container along the perforations from the edge or periphery of the blister pack is effectively avoided.
  • a user can separate the foil container only from the center in order to access the receiving chamber or to separate the foil container from the remaining blister pack.
  • the film containers are arranged with the outer contour of a polygon, circle or oval to each other.
  • the arrangement allows a plurality of film containers to be assembled into a blister pack, wherein each film container can only be opened from the center.
  • the object is achieved according to the invention in a blister pack with a bottom foil and a cover sheet to form a plurality separable by perforations foil container, each having a receiving chamber for a product, in particular a pharmaceutical active ingredient formulation, wherein the square-shaped film containers are arranged in a matrix, achieved that the Film containers are spirally separable, wherein between each two adjacent film containers partially the perforation and in the region of the perforation an opening area for removal of the filling material from the receiving chamber is present.
  • the opening region is designed as a grip tab for removing the cover film.
  • the cover film is not fully connected in the opening area with the bottom film or less firmly sealed.
  • the cover sheet which rests relatively loosely on the bottom sheet or is relatively easy to peel off the bottom sheet in the opening area for opening the receiving chamber and for removal of the contents can be easily lifted by a user from the bottom sheet and peeled off or torn to the To be able to access contents in the receiving chamber.
  • the opening region has a notch or a cut as weakening of the bottom foil and / or the cover foil.
  • the notch or the cut extends centrally from an edge region of the film container in the direction of the receiving chamber.
  • the foil container to remove the contents is torn up to the receiving chamber.
  • the blister pack can be provided with appropriate labels or imprints consisting of digits, day of the week or the like to illustrate the correct order of removal of the contents of the receiving chambers.
  • the bottom foil preferably consists of plastic, aluminum or a composite of these materials.
  • the shape, size and number of the respective cavities of the receiving chambers in the bottom foil is matched to the male contents, such as a tablet or the like.
  • a single blister package may include a plurality of film containers with the corresponding number of receiving chambers.
  • the bottom foil is, for example, on the side facing the product from an approximately 60 micron thick layer of polyvinyl chloride (PVC), followed by an approximately 45 microns thick aluminum foil, which in turn with an approximately 25 micron thick film of an oriented polyamide (oPA) is made.
  • PVC polyvinyl chloride
  • oPA oriented polyamide
  • the cover film is an aluminum composite film, which, for example, on the side facing the contents consists of an approximately 20 microns thick aluminum foil and an associated about 23 micron thick film of a polyethylene terephthalate (PET).
  • PET polyethylene terephthalate
  • the bottom sheet and the cover sheet may also be identical or made of other materials.
  • the blister pack 7 having a plurality of film containers 1 comprises a bottom film with cavities 8 and a cover film, which is connected in a suitable manner, preferably by a heat seal lacquer, to the bottom film in order to close at least 8 cavities 8 for each at least one product, in particular one pharmaceutical drug formulation to form.
  • Fig. 1 are in the blister pack 7, the individual film container 1 in the form of a polygon arranged to each other and the individual receiving chambers 2 are located on the peripheral periphery of the blister 7.
  • a film section 4 is arranged, in which no receiving chamber 2 is formed and by a substantially circular perforation 3 is detachable from the blister pack 7.
  • opening regions 5 for opening the receiving chambers 2 of the segment-shaped film containers 1 adjoin the film section 4.
  • the individual film containers 1 are separable from one another by perforations 10 which emerge from the perforation 3, wherein the perforations 10 do not extend between the film containers 1 to the periphery of the blister packaging 7, thus separating the film containers 1 from the outside difficult and easy to accomplish from the direction of the center after removing the film section 4.
  • the film section 4 in the center of the blister pack 7 along the perforation 3, which is formed continuously around its circumference, must be cut out.
  • the opening region 5 is formed as a grip tab 9 for removing the cover film from the bottom film, the cover film in the opening region 5 is not connected to the bottom film over the entire surface or less firmly sealed.
  • Fig. 3 are in the alternative blister packaging 7 square-shaped film container 1 arranged in a matrix, which are spirally separable. Between each two adjacent film containers 1 is partially perforation 11 and in the region of the perforation 11 of the opening area 5 for removing the filling material from the receiving chamber 2 is present, wherein the opening portion 5, as explained above, may be formed. In some areas of the blister pack 7 there is no perforation 11 between the film containers 1 to ensure spiral separation. In the areas without perforation 11, a material weakening of the bottom foil and the cover foil may be formed in order to make the separation of the foil container 1 difficult, but nevertheless possible. To illustrate the order of removal of the individual film containers 1, the blister pack 7 is printed with digits 1 to 30 accordingly.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Composite Materials (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Packages (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Claims (12)

  1. Emballage à blister avec un film de fond et un film de recouvrement pour la réalisation de plusieurs récipients de film (1) pouvant être séparés les uns des autres par des perforations (10) avec respectivement une chambre de réception (2) pour un matériau de remplissage, en particulier une formulation de substance active pharmaceutique, sachant que les chambres de réception (2) sont disposées sur la périphérie de l'emballage à blister (7), caractérisé en ce que le centre de l'emballage à blister (7) est formé par une section de film (4) séparable, après le retrait de laquelle une zone d'ouverture (5) est présente pour l'ouverture de la chambre de réception (2).
  2. Emballage à blister selon la revendication 1, caractérisé en ce qu'une perforation (3) s'étendant autour de la section de film (4) comme un cercle est associée à celle-ci.
  3. Emballage à blister selon la revendication 1, caractérisé en ce que les récipients de film (1) peuvent être séparés par segment.
  4. Emballage à blister selon l'une quelconque des revendications 1 à 3, caractérisé en ce que la perforation (10) entre les récipients de film (1) ne s'étend pas jusqu'à la périphérie extérieure de l'emballage à blister (7).
  5. Emballage à blister selon l'une quelconque des revendications 1 à 4, caractérisé en ce que les récipients de film (1) présentant le contour extérieur d'un polygone, d'un cercle ou d'un ovale sont disposés les uns par rapport aux autres.
  6. Emballage à blister avec un film de fond et un film de recouvrement pour la réalisation de plusieurs récipients de film (1) pouvant être séparés les uns des autres par des perforations (11) avec respectivement une chambre de réception (2) pour un matériau de remplissage, en particulier une formulation de substance active pharmaceutique, sachant que les récipients de film (1) carrés sont disposés en forme de matrice, caractérisé en ce que les récipients de film (1) peuvent être séparés en spirale, sachant qu'entre respectivement deux récipients de film contigus (1), la perforation (11) est présente par endroits et dans la zone de la perforation (11), une zone d'ouverture (5) est présente pour le retrait du matériau de remplissage de la chambre de réception (2).
  7. Emballage à blister selon l'une quelconque des revendications 1 à 6, caractérisé en ce que la zone d'ouverture (5) est réalisée comme une languette de saisie (9) pour le retrait du film de recouvrement.
  8. Emballage à blister selon l'une quelconque des revendications 1 à 6, caractérisé en ce que la zone d'ouverture (5) présente une entaille ou une coupure (6) servant d'affaiblissement du film de fond et/ou du film de recouvrement.
  9. Emballage à blister selon la revendication 8, caractérisé en ce que l'entaille ou la coupure (6) s'étend d'une zone de bord du récipient de film (1) au milieu dans la direction de la chambre de réception (2).
  10. Emballage à blister selon l'une quelconque des revendications 1 à 9, caractérisé par des inscriptions ou surimpressions qui se composent de chiffres, indications de jours de la semaine ou similaires.
  11. Emballage à blister selon l'une quelconque des revendications 1 à 10, caractérisé en ce que le film de fond se compose de plastique, d'aluminium ou d'un composé de ces matériaux.
  12. Emballage à blister selon l'une quelconque des revendications 1 à 10, caractérisé en ce que le film de recouvrement est un film composite d'aluminium.
EP09781315A 2008-08-11 2009-07-30 Emballage à blister Not-in-force EP2323918B1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP09781315A EP2323918B1 (fr) 2008-08-11 2009-07-30 Emballage à blister

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08162175 2008-08-11
EP09781315A EP2323918B1 (fr) 2008-08-11 2009-07-30 Emballage à blister
PCT/EP2009/059906 WO2010018077A1 (fr) 2008-08-11 2009-07-30 Emballage à blister

Publications (2)

Publication Number Publication Date
EP2323918A1 EP2323918A1 (fr) 2011-05-25
EP2323918B1 true EP2323918B1 (fr) 2012-02-01

Family

ID=41070668

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09781315A Not-in-force EP2323918B1 (fr) 2008-08-11 2009-07-30 Emballage à blister

Country Status (6)

Country Link
US (2) US20110198261A1 (fr)
EP (1) EP2323918B1 (fr)
JP (1) JP5314139B2 (fr)
AT (1) ATE543743T1 (fr)
CA (1) CA2733495A1 (fr)
WO (1) WO2010018077A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2516291A1 (fr) * 2009-12-22 2012-10-31 Boehringer Ingelheim International GmbH Contenant constitué de feuilles d'un blister ne pouvant pas être ouvert par application d'une pression
EP2547308B1 (fr) 2010-03-18 2014-08-06 MedComb Holding ApS Récipient rigide jetable pour compositions pharmaceutiques
US20150298879A1 (en) * 2012-11-30 2015-10-22 Unitika Ltd. Packaging material for cold forming and press-through pack formed using same
EP2928684B1 (fr) 2012-12-07 2019-07-17 Bemis Company, Inc. Film multicouche
US20150225151A1 (en) 2014-02-11 2015-08-13 Christopher L. Osborn Anti-Scalping Transdermal Patch Packaging Film
US9468584B2 (en) 2014-04-02 2016-10-18 Bemis Company, Inc. Child-resistant packaging
WO2016077439A2 (fr) * 2014-11-11 2016-05-19 Dufour Brian Systèmes et ensembles de médicaments à dose unique stratifiés multiples
US11147780B2 (en) * 2020-02-24 2021-10-19 Algia Pharma, Llc Multidrug pain management package

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4518131Y1 (fr) * 1967-07-20 1970-07-24
JPS5411256Y2 (fr) * 1973-12-28 1979-05-22
US5551567A (en) * 1994-04-29 1996-09-03 Mcneil-Ppc, Inc. Blister package containing gripping means
US6036016A (en) * 1998-04-20 2000-03-14 Pinnacle Intellectual Property Services, Inc. Blister package with easy tear blister
US6230894B1 (en) * 1998-10-22 2001-05-15 Novartis Pharmaceuticals Corp. Child resistant package and method of dispensing medication
US20020045184A1 (en) * 2000-10-02 2002-04-18 Chih-Ming Chen Packaging system
DE10102818A1 (de) * 2001-01-23 2002-08-08 Lohmann Therapie Syst Lts Primärverpackungseinheit für mehrere vereinzelte Filmplättchen als Darreichungsformen
DE20314741U1 (de) * 2003-09-24 2004-01-15 Amthor, Günter Medikament-Kalender
DE102004027590B3 (de) * 2004-06-05 2005-11-17 Romaco Pharmatechnik Gmbh Blisterpackung
DE102004062864A1 (de) * 2004-12-21 2006-06-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Folienbehälter
US7395928B2 (en) * 2005-07-14 2008-07-08 Abbott Laboratories Child-resistant blister package
JP3117622U (ja) * 2005-09-22 2006-01-12 健一朗 中島 服用タイミング表示付き周回状ブリスターパック
US7828149B2 (en) * 2007-05-22 2010-11-09 Multi-Comp, Inc. Sealed blister assembly

Also Published As

Publication number Publication date
EP2323918A1 (fr) 2011-05-25
ATE543743T1 (de) 2012-02-15
WO2010018077A1 (fr) 2010-02-18
US20110198261A1 (en) 2011-08-18
US20130153460A1 (en) 2013-06-20
JP2011530460A (ja) 2011-12-22
CA2733495A1 (fr) 2010-02-18
JP5314139B2 (ja) 2013-10-16

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