EP2300825A4 - Procédés de diagnostic par compagnon p/gf-1 et produits - Google Patents

Procédés de diagnostic par compagnon p/gf-1 et produits

Info

Publication number
EP2300825A4
EP2300825A4 EP09767690A EP09767690A EP2300825A4 EP 2300825 A4 EP2300825 A4 EP 2300825A4 EP 09767690 A EP09767690 A EP 09767690A EP 09767690 A EP09767690 A EP 09767690A EP 2300825 A4 EP2300825 A4 EP 2300825A4
Authority
EP
European Patent Office
Prior art keywords
products
diagnostic methods
companion diagnostic
companion
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09767690A
Other languages
German (de)
English (en)
Other versions
EP2300825A1 (fr
Inventor
Saul Datwyler
David J Hawksworth
Don M Laird
Dominick L Pucci
David C Sogin
Joan D Tyner
Robert N Ziemann
Richard R Lesniewski
Evelyn Mary Mckeegan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/485,114 external-priority patent/US8741287B2/en
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of EP2300825A1 publication Critical patent/EP2300825A1/fr
Publication of EP2300825A4 publication Critical patent/EP2300825A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
EP09767690A 2008-06-18 2009-06-17 Procédés de diagnostic par compagnon p/gf-1 et produits Withdrawn EP2300825A4 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US7362408P 2008-06-18 2008-06-18
US8917208P 2008-08-15 2008-08-15
US11006308P 2008-10-31 2008-10-31
US12/485,114 US8741287B2 (en) 2008-06-18 2009-06-16 PlGF-1 assay and kits and components thereof
PCT/US2009/047714 WO2009155381A1 (fr) 2008-06-18 2009-06-17 Procédés de diagnostic par compagnon p/gf-1 et produits

Publications (2)

Publication Number Publication Date
EP2300825A1 EP2300825A1 (fr) 2011-03-30
EP2300825A4 true EP2300825A4 (fr) 2012-04-25

Family

ID=41434433

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09767690A Withdrawn EP2300825A4 (fr) 2008-06-18 2009-06-17 Procédés de diagnostic par compagnon p/gf-1 et produits

Country Status (6)

Country Link
EP (1) EP2300825A4 (fr)
JP (1) JP2011525241A (fr)
CN (1) CN102224419A (fr)
CA (1) CA2728449A1 (fr)
MX (1) MX2010014228A (fr)
WO (1) WO2009155381A1 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4785252B2 (ja) 1999-02-26 2011-10-05 ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア Ｔｒｐｍ−２アンチセンス療法
US7569551B2 (en) 2000-02-25 2009-08-04 The University Of British Columbia Chemo- and radiation-sensitization of cancer by antisense TRPM-2 oligodeoxynucleotides
CA2790097A1 (fr) * 2010-03-05 2011-09-09 Ophthalmopharma Ag Chocolat nutraceutique ou produit compose a base de chocolat
SG10201806648TA (en) 2011-07-01 2018-09-27 Ngm Biopharmaceuticals Inc Compositions, uses and methods for treatment of metabolic disorders and diseases
UY34812A (es) * 2012-05-18 2013-12-31 Teva Pharma Método para el tratamiento del cáncer de pulmón de células no pequeñas
US9963494B2 (en) 2012-11-28 2018-05-08 Ngm Biopharmaceuticals, Inc. Methods of using compositions comprising variants and fusions of FGF19 polypeptides for reducing glucose levels in a subject
US9290557B2 (en) 2012-11-28 2016-03-22 Ngm Biopharmaceuticals, Inc. Compositions comprising variants and fusions of FGF19 polypeptides
CN108888757A (zh) 2012-12-27 2018-11-27 恩格姆生物制药公司 用于调节胆汁酸体内稳态及治疗胆汁酸紊乱和疾病的方法
US9273107B2 (en) 2012-12-27 2016-03-01 Ngm Biopharmaceuticals, Inc. Uses and methods for modulating bile acid homeostasis and treatment of bile acid disorders and diseases
WO2015183890A2 (fr) 2014-05-28 2015-12-03 Ngm Biopharmaceuticals, Inc. Méthodes et compositions pour le traitement de maladies et de troubles métaboliques
AU2015277438B2 (en) 2014-06-16 2020-02-27 Ngm Biopharmaceuticals, Inc. Methods and uses for modulating bile acid homeostasis and treatment of bile acid disorders and diseases
UA123763C2 (uk) 2014-10-23 2021-06-02 Енджіем Байофармасьютикалз, Інк. Фармацевтична композиція для контролю або лікування захворювання або порушення, пов’язаного з fgf19
US10434144B2 (en) 2014-11-07 2019-10-08 Ngm Biopharmaceuticals, Inc. Methods for treatment of bile acid-related disorders and prediction of clinical sensitivity to treatment of bile acid-related disorders
AU2016353988B2 (en) 2015-11-09 2019-09-26 Ngm Biopharmaceuticals, Inc. Methods for treatment of bile acid-related disorders
MX2018009112A (es) * 2016-01-25 2018-08-28 Sanofi Sa Metodo para predecir el resultado de un tratamiento con aflibercept de un paciente que se sospecha que padece un cancer mediante la medicion del nivel de un biomarcador plasmatico.
US11370841B2 (en) 2016-08-26 2022-06-28 Ngm Biopharmaceuticals, Inc. Methods of treating fibroblast growth factor 19-mediated cancers and tumors
GB2616177A (en) * 2020-11-10 2023-08-30 Ningbo Aucheer Biotechnology Co Ltd Hybridoma cell strain 9C1, PLGF-1 monoclonal antibody, preparation method therefor and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070037224A1 (en) * 2005-08-11 2007-02-15 Hamer Peter J Quantitative assays for PDGFR-beta in body fluids
US20070254295A1 (en) * 2006-03-17 2007-11-01 Prometheus Laboratories Inc. Methods of predicting and monitoring tyrosine kinase inhibitor therapy

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030049262A1 (en) * 1998-10-02 2003-03-13 Susan Love Methods for identification, diagnosis, and treatment of breast cancer
US7435419B2 (en) * 2002-07-19 2008-10-14 Beth Israel Deaconess Medical Center Methods of diagnosing and treating pre-eclampsia or eclampsia
US7767792B2 (en) * 2004-02-20 2010-08-03 Ludwig Institute For Cancer Research Ltd. Antibodies to EGF receptor epitope peptides
DE102005022047A1 (de) * 2005-05-09 2006-11-30 Dade Behring Marburg Gmbh Bindungspartner des Plazentalen Wachstumsfaktors insbesondere gegen den Plazentalen Wachstumsfaktor gerichtete Antikörper, ihre Herstellung und Verwendung
CN101534865A (zh) * 2005-10-19 2009-09-16 Ibc药品公司 生物活性装配体的制备方法及其用途
CA2626054A1 (fr) * 2005-11-02 2007-05-18 Bayer Healthcare Llc Methodes pour la prevision et le pronostic du cancer, et pour la surveillance de therapie anticancereuse
CN101517078A (zh) * 2006-05-31 2009-08-26 貝丝以色列女执事医疗中心 诊断和治疗妊娠并发症的方法
US20080071151A1 (en) * 2006-06-30 2008-03-20 Sogin David C Method and Apparatus for Diagnosing Pre-eclampsia
CA2667720A1 (fr) * 2006-11-09 2008-05-15 Abbott Gmbh & Co. Kg. Forme de dosage pharmaceutique pour l'administration orale d'un inhibiteur de la tyrosine kinase

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070037224A1 (en) * 2005-08-11 2007-02-15 Hamer Peter J Quantitative assays for PDGFR-beta in body fluids
US20070254295A1 (en) * 2006-03-17 2007-11-01 Prometheus Laboratories Inc. Methods of predicting and monitoring tyrosine kinase inhibitor therapy

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ALBERT D H ET AL: "Preclinical activity of ABT-869, a multitargeted receptor tyrosine kinase inhibitor", MOLECULAR CANCER THERAPEUTICS, AMERICAN ASSOCIATION OF CANCER RESEARCH, US, vol. 5, no. 4, 1 April 2006 (2006-04-01), pages 995 - 1006, XP002403181, ISSN: 1535-7163 *
CHIUNG-NIEN CHEN ET AL: "The significance of placenta growth factor in angiogenesis and clinical outcome of human gastric cancer", CANCER LETTERS, vol. 213, no. 1, 1 September 2004 (2004-09-01), pages 73 - 82, XP055020729, ISSN: 0304-3835, DOI: 10.1016/j.canlet.2004.05.020 *
EBOS JOHN M L ET AL: "Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol. 104, no. 43, 23 October 2007 (2007-10-23), pages 17069 - 17074, XP055020654, ISSN: 0027-8424 *
See also references of WO2009155381A1 *
SOO ET AL: "The effect of varying doses of ABT-869 on biomarkers of angiogensis and their correlation with pharmacodynamic outcome", no. Abst. 14535, May 2008 (2008-05-01), pages 1 - 2, XP002670638, Retrieved from the Internet <URL:http://tinyurl.com/847l6aq> [retrieved on 20120229] *

Also Published As

Publication number Publication date
JP2011525241A (ja) 2011-09-15
CA2728449A1 (fr) 2009-12-23
EP2300825A1 (fr) 2011-03-30
WO2009155381A1 (fr) 2009-12-23
MX2010014228A (es) 2011-03-29
CN102224419A (zh) 2011-10-19

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Inventor name: PUCCI, DOMINICK, L.

Inventor name: MCKEEGAN, EVELYN, MARY

Inventor name: ZIEMANN, ROBERT, N.

Inventor name: TYNER, JOAN, D.

Inventor name: SOGIN, DAVID, C.

Inventor name: HAWKSWORTH, DAVID, J.

Inventor name: DATWYLER, SAUL

Inventor name: LAIRD, DON, M.

Inventor name: LESNIEWSKI, RICHARD, R.

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