EP2210668A2 - Support pour pointes de pipettes - Google Patents

Support pour pointes de pipettes Download PDF

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Publication number
EP2210668A2
EP2210668A2 EP10000090A EP10000090A EP2210668A2 EP 2210668 A2 EP2210668 A2 EP 2210668A2 EP 10000090 A EP10000090 A EP 10000090A EP 10000090 A EP10000090 A EP 10000090A EP 2210668 A2 EP2210668 A2 EP 2210668A2
Authority
EP
European Patent Office
Prior art keywords
frame
plate
carrier according
lid
holes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP10000090A
Other languages
German (de)
English (en)
Other versions
EP2210668B1 (fr
EP2210668A3 (fr
Inventor
Michael Blumentritt
Hanna Rethwisch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eppendorf SE
Original Assignee
Eppendorf SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eppendorf SE filed Critical Eppendorf SE
Publication of EP2210668A2 publication Critical patent/EP2210668A2/fr
Publication of EP2210668A3 publication Critical patent/EP2210668A3/fr
Application granted granted Critical
Publication of EP2210668B1 publication Critical patent/EP2210668B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/54—Supports specially adapted for pipettes and burettes
    • B01L9/543—Supports specially adapted for pipettes and burettes for disposable pipette tips, e.g. racks or cassettes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/025—Align devices or objects to ensure defined positions relative to each other
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/028—Modular arrangements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates

Definitions

  • the invention relates to a carrier for pipette tips, in particular for machine tips.
  • Pipette tip carriers are for storing and providing plastic pipette tips for use. They have an edge with four upstanding side walls and a plate arranged at the top of the frame with a plurality of holes in a matrix arrangement. Pipette tips are inserted into the holes from above, but do not fall through due to an upwardly broadening diameter or collar.
  • the frame can be placed on a base with the bottom edge or a bottom. The pipette tips are held by the carrier at a distance from the base.
  • One or more pipette tips can be removed from the carrier by means of a pipetting or metering device. For this purpose, the metering device is pressed with one or more approaches in the upper opening of one or more pipette tips. After use, the pipette tips are usually inserted into a carrier by means of a disposable device of the metering device or dispensed into a container for disposal.
  • Carriers for pipette tips are known in which the frame is covered at the bottom by a bottom and at the top by a detachable lid. In these box-like carriers, the pipette tips are protected from contamination. Before removing pipette tips, remove the cover.
  • the refill pack includes a matrixed array plate in which pipette tips are inserted, and a flexible lid in which the plate is held.
  • a matrixed array plate in which pipette tips are inserted
  • a flexible lid in which the plate is held.
  • the side walls of the lid are deflected laterally, so that the plate clamped therebetween is released.
  • the plate with the pipette tips falls into a receptacle of the carrier surrounded by an enclosure.
  • the refilling of pipette tips into the carrier and the removal of the plate with pipette tips from the carrier are done manually.
  • Pipette tips made of plastic are often used in automatic dispensing machines and dosing devices having "work stations". Dosing machines and laboratory machines are referred to below as “machines”. The well-known Nachfiillpackung is not well suited for use in machines. A shift of the lid by a machine for the purpose of separating the plate and lid would be problematic because of its flexibility. When the plate is placed in the carrier, the lateral enclosure obstructs removal by a vending machine.
  • a pipette tip box which has a base with a bottom and sidewalls that terminate at the top in support surfaces.
  • a plurality of locking elements is arranged asymmetrically on the support surfaces.
  • a plurality of bottom-raised, inner walls bounded to a plurality of internal receptacles.
  • a plate member has a first set of holes into which the Locking elements are used. It also has a second set of holes for inserting pipette tips.
  • the locking elements are formed as locking pins which frictionally engage in the first set of holes of the plate. Plate and base are thus releasably secured to each other by means of the pins and the holes.
  • a detachment of the plate from the lower part is only possible under force, which is greater than the weight of the lower part and plate.
  • the user can choose among plates with 96, 384 and 1536 holes for inserting pipette tips. He can fix the selected plate by means of the locking pins and the holes on the lower part. He can then insert the pipette tips into the holes and place a lid over the plate.
  • the object of the invention is to provide a carrier for pipette tips, which is particularly suitable for use in vending machines. That is, the carrier is characterized by its special stability and manageability by machine elements (eg gripper arms, dosing head).
  • An essential aspect of the object is therefore to provide a carrier available whose plate and frame can not be accidentally separated, for example by machine error, whose elements (plate and frame) but, if desired, are easily solvable.
  • the guide elements are aligned perpendicular to the contact surfaces. But they can also be aligned obliquely to the contact surfaces. Due to the arrangement of the contact surfaces, the plate is not or only partially covered by the frame laterally. As a result, a gripping tool of a machine can access the edges of the disk to place a disk on the frame or remove it from the frame. The edges of the plate are thus usable for transport by means of a gripping tool.
  • the plate In the direction of this load by a gripping tool, the plate is relatively stiff, so that it resists the clamping force of the gripping tool and can be held securely by this. Due to the interlocking guide elements of the means for releasably connecting the plate is securely held on the frame.
  • the guide elements of frame and plate engage each other with lateral play. This interplay between the intermeshing guide elements facilitates the assembly of the plate and frame, making it easier to automate. This also applies to the lifting of the plate from the frame in the course of the exchange of an empty flap through a full plate.
  • the clearance-intermeshing parts of the plate and frame are able to compensate for inaccuracies of an automatically operated gripping device.
  • a pre-filled plate with pipette tips can be placed on the frame, so that the carrier automatically with
  • Pipette tips is befiillbar.
  • the plate may e.g. 24, 48, 96, 384 or 1536 holes for inserting pipette tips. If in an erroneous removal by a dosing it comes to a hooked pipette tip and thereby the plate is raised and threatens to fall out, it comes between the intermeshing with lateral play guide elements to a tilt, the loosening of the entangled pipette tip of the plate to result so that the plate slides back to its original position in the frame. This intentional canting thus prevents unintentional separation of the plate from the frame and increases the safety of the automatic processes. In particular, so the continuation of the automatic pipetting process is ensured, without manual intervention is required.
  • the invention includes embodiments in which the frame and the plate are each provided with only two guide elements which are engageable with each other.
  • the frame and the plate each have a plurality of guide elements, in particular four, wherein each guide element of the frame, a guide element of the plate is associated and the mutually associated guide elements are engageable with each other.
  • the associated guide elements of frame and plate are arranged at different positions of the frame and plate. Preferably, they are arranged on opposite side walls of the frame and on opposite edges of the plate. Further preferably, they are arranged at diametrically opposite positions of the side walls and the edges of the plate.
  • the guide elements which can be brought into engagement with one another with lateral play can be designed differently.
  • it is an upper opening of the frame and an insertable into the upper opening with play collar on the underside of the plate.
  • the guide elements on columns and for inserting the columns with lateral clearance suitable holes and / or ribs and for inserting the ribs with lateral clearance suitable grooves. Due to the clearance, the inner diameter of the holes or the width of the grooves exceeds the outer diameter of the columns or the wall thickness of the ribs.
  • the columns and / or the ribs project from the upper edge of the frame and the plate has the bores and / or grooves on the underside.
  • the invention also relates to embodiments in which the columns and / or ribs project from the underside of the plate and the upper edge of the frame has the holes and / or grooves.
  • embodiments are included in which the upper edge of the frame columns and / or ribs and holes and / or grooves the bottom of the plate corresponding holes and / or grooves and columns and / or ribs.
  • the holes may be through holes or blind holes and the grooves may have a groove bottom or be configured as through slots.
  • the columns can have different shapes. For example, they may be cylindrical and have a circular or polygonal cross-section. The same applies to the holes.
  • the ribs can be one have constant wall thickness. Furthermore, they can have a straight, angular or curved course. The same applies to the grooves.
  • the pillars taper at least in sections towards their free end and / or the bores expand at least in sections towards their insertion opening for the pillars.
  • the columns can also taper over their entire height and / or widen the holes over their entire depth.
  • the ribs may taper at least in sections to their free end and / or expand the grooves at least in sections to their Ein slaughterfn 11, for the ribs out.
  • the ribs can also taper over their entire height and / or widen the grooves over their entire depth.
  • the tapered columns or ribs and the widening holes or grooves facilitate the assembly of the plate with the frame and thus facilitate handling by machines.
  • the columns and the bores are arranged at the corners of the frame and the plate.
  • the invention includes embodiments in which the pillars and the bores are arranged between the corners of the frame and the plate.
  • the frame has a waist.
  • the waist favors a positive and secure gripping of the entire carrier by means of a gripping device of a machine.
  • the waist thus promotes safe and accurate positioning of the entire wearer. Due to the waist, the wearer can be gripped safely with low gripping force.
  • the waist is formed by two opposite side walls of the frame. It is preferred formed between all opposing side walls, so that the carrier can be gripped safely from two directions.
  • the waist may be formed for example by depressions in the outer sides of opposing side walls. According to one embodiment, the waist is bounded at the top by an outwardly projecting upper projection of the frame. This limitation may prevent the carrier from falling out of a gripping device. Further, the waist may be bounded below by an outwardly projecting lower protrusion of the frame. Due to the configuration of the waist, the bending force can be optimized when gripping by means of a gripping device, so that the frame withstands the loads of the gripping device.
  • the invention includes embodiments in which the frame is open at the bottom.
  • This frame can be placed with a lower edge on a base.
  • the frame is closed at the bottom by a floor.
  • the bottom protects pipette tips from the bottom against contamination.
  • the lower protrusion may be formed by an edge of the floor projecting outwardly beyond the side walls.
  • the dimensions of the base area of the frame correspond to the dimensions of the base area of microtiter plates according to the standard of the "Society for Biomolecular Screening (SBS)".
  • SBS Society for Biomolecular Screening
  • This standard was published by the American National Standards Institute (ANSI) under the name “ANSI / SBS 1-2004” and is referred to below as "SBS standard".
  • ANSI American National Standards Institute
  • ANSI / SBS 1-2004 a microtiter plate has a footprint with a length of 127.76 mm and a width of 85.48 mm.
  • the base of the frame has the same dimensions.
  • Conventional vending machines have storage locations for microtiter plates of the stated dimensions.
  • These bearing positions are provided with guiding and clamping devices, which are adapted to the dimensions mentioned.
  • These bearing positions and guiding and clamping devices can be used for the positioning of the carrier, which has a base according to SBS standard.
  • a waist allows compliance with the SBS standard
  • the frame between the side walls has a free cross-section.
  • the side walls are not connected to each other by inner walls, as in the carrier according to US 6,221,317 B1 , Consequently, placing a plate with inserted pipette tips on the frame can not be hindered by the pipette tips colliding with internal walls in the frame.
  • the side walls are internally provided with vertically extending ribs which stiffen the side walls. The vertically extending ribs may be sized so that they only slightly into the interior of the frame and between the side walls a large free cross section for receiving pipette tips remains.
  • the plate in each case on at least two opposite edges on a standing over the top of the plate beyond the gripping edge.
  • the gripping edges can be used as additional contact surfaces of the gripping tool of a machine. Further, the gripping edges may serve as protective and gripping edges to prevent contamination of the pipette tips when manually loading a carrier with the plate. Preferably, the gripping edges are at least as far from the top of the plate as pipette tips inserted into the plate.
  • the gripping edges can be arranged on the two longitudinal edges of the plate. In addition or instead, however, they can also be arranged on the two end edges of the plate.
  • the carrier has a lid with a lid bottom and from the edge of the lid bottom downwardly projecting lid side walls, which are placed on the frame.
  • the lid covers the top of pipette tips held in the frame by means of a plate.
  • For a positioning of the lid on the support of the frame has an outer circumferential step on which the lid with the lower edge of the lid side walls can be placed. The exact positioning favors the sealing of the lid to the frame.
  • the outer circumferential step may be formed on an outwardly projecting upper protrusion defining a waist.
  • the frame has an edge surface delimiting the step outside, which, with the cover on, has a further edge bounding the lower edge of the cover side walls on the outside Edge surface is aligned.
  • the mutually aligned edge surfaces can be used for attaching a sealing tape.
  • the adhesive tape ensures sterile storage of pipette tips in the carrier.
  • the outer dimensions of the base area exceed the outer dimensions of the frame in the region of the upper edge surface. In this way it can be ensured that even when an adhesive tape is applied for sealing a lid, the dimensions of the carrier do not exceed the SBS format.
  • the difference in dimensions is preferably 0.05 to 1 mm. It is preferably 0.1 to 0.5 mm.
  • the floor is a hollow floor with a downwardly projecting enclosure, which can be placed on the upper edge of the lid.
  • the enclosure can laterally overlap the lid side walls or the guide staircase that rises from the lid. This allows a secure stacking of several carriers each other.
  • the lid comprises depressions in the outer sides of two mutually opposite side walls.
  • the recesses allow a positive contact with a gripping tool of a machine and thus facilitate the automatic lifting of the lid.
  • the wells facilitate transparent reading of a label on the upper edge of the carrier, which may be formed for example as a bar code.
  • the carrier comprises a frame-shaped spacer which can be placed with the lower edge outside the holes on the upper side of a plate and with the upper edge outside the holes on the underside of a plate.
  • the spacer allows stacking of multiple tips filled with pipette tips on a single frame. The lowest plate filled with pipette tips is arranged directly on the frame. On a spacer and thereon again a filled with pipette tips plate is arranged.
  • further spacers and plates are alternately arranged thereon. The spacer prevents pipette tips arranged in different plates from being pressed into one another and when lifting a plate, the pipette tips are also lifted off from a plate arranged underneath.
  • the spacer has, according to one embodiment, a false bottom with further holes.
  • the pipette tips are guided by the further holes so that they are safely guided into the upper openings of pipette tips which are in one below arranged plate are inserted.
  • the further holes are dimensioned such that when lifting a plate with inserted pipette tips prevent pipette tips are lifted from a plate arranged thereunder with.
  • the pipette tips from the lower plate are retained at the holes and fall back into the lower plate.
  • the stack is superimposed by the partially interdigitated pipette tips positioned plates arranged. On the top plate a lid is loosely positionable.
  • top and bottom as well as “vertical” and “horizontal” refer to arrangements of the carrier in which this with a lower edge or a bottom of the frame a base is placed and held in a mounted on the frame plate pipette tips are kept at a distance from the ground.
  • a frame 1 has four side walls 2, 3, 4, 5. Of these, two opposing side walls 2, 4 are longer than two further opposing side walls 3, 5.
  • the side walls 2 to 5 are high from a bottom 6.
  • the bottom 6 has an approximately rectangular shape. Outside, he stands a little above the side walls 2 to 5. Its length and width correspond to the dimensions of the base according to SBS standard.
  • the frame 1 has at the upper edge 7 a flat contact surface 8, which runs along the side walls 2 to 5 parallel to the bottom 6 and horizontal. At the corners between the side walls 2 to 5, the contact surface 8 is slightly widened. In each corner is perpendicular to the contact surface 8 before a column 9, which has a conical base portion 10, a cylindrical central portion 11 and a conical end portion 12.
  • a step 14 which is also flat and parallel to the bottom 6.
  • the upper projection 13 is arranged slightly below the contact surface 8.
  • the step 14 is bounded by a circumferential, vertically aligned edge surface 15 of the upper projection 13. Between the upper projection 13 and contact surface 8 are from the frame 1 positioning lugs 16 outward.
  • the upper projection 13 and the bottom projecting bottom 6 define a circumferential waist 17 of the frame 1.
  • the bottom 6 is a hollow floor with a downwardly projecting, circumferential enclosure 19, whose bottom is flat and forms a footprint. Further, from the bottom of the bottom 6 parallel to its transverse edges extending ribs 20 are present (see. Fig. 6 ).
  • the frame 1 can be made of several parts. Preferably, it is made in one piece. Further preferably, it is made of plastic. Preferably, he is injection molded. To create the waist 17, the frame 1 must be injection molded by means of a pusher tool.
  • Suitable materials are in particular polypropylene (PP), polycarbonate (PC), acrylonitrile-butadiene-styrene copolymers (ABS), polystyrene (PS) or a metal (eg aluminum, optionally anodized) into consideration.
  • Polypropylene is particularly inexpensive. Polycarbonate and metal have the advantage of autoclaving and thus reusability.
  • the frame is made of polypropylene. It can be used unfilled or filled (eg with glass fibers) polypropylene. Filled polypropylene has a higher strength than unfilled polypropylene.
  • a plate 21 has a substantially plate-shaped main body 22 with a plurality of holes 23 which extend from the bottom 24 to the top 25 of the main body 22.
  • the holes 23 are regularly arranged in rows and columns of a matrix. In the example it is 96.
  • the plate 21 has two short edges 26, 27 and two long edges 28, 29. At the long edges 28, 29, they each have an over the top 25 upstanding, plate-shaped gripping edge 30, 31.
  • the plate-shaped base body 22 has at the bottom 24 a further flat contact surface 32 which rotates at the edge.
  • the further contact surface 32 is arranged slightly above the lower openings of the holes 23.
  • In the corners of the plate-shaped base body 22 has broadening, in which through holes 33 are arranged.
  • Each bore 33 has a conical portion 34 at the bottom and a cylindrical portion 35 adjacent thereto.
  • the dimensions of the bores 33 are selected so that the columns 9 can be inserted with play.
  • the conical sections 34 form chamfers, which facilitate the insertion of the columns 9 in the holes 33.
  • the conical end portions 12 of the columns 9 facilitate insertion into the bores 33.
  • the plate-shaped base body 22 is configured as a quiver plate.
  • the holes 23 in quiver or sleeve-shaped Structures formed laterally connected by webs and at the top by a plate and bordered by a circumferential edge.
  • the plate 21 may also be formed as a web plate, wherein a thin plate having a plurality of holes 23 at the bottom has the holes enclosing webs. Designs as quiver or web plate are material-saving and stable and laterally support the pipette tips inserted in holes.
  • the plate 21 may also be made solid, ie without cavities outside the holes 23 and holes 33rd
  • the plate 21 is preferably made in one piece. Further preferably, it is made of plastic. Preferably, it is injection molded. In particular, the plastics polypropylene (PP), polycarbonate (PC), acrylonitrile-butadiene-styrene copolymers (ABS), polystyrene (PS) can be used.
  • the frame 1 and the plate 21 may be made of the same or different materials.
  • the frame 1 can be inexpensively made of polypropylene and the plate 21 made of polycarbonate, so that the plate is particularly stable.
  • Another example is an autoclavable frame 1 made of polycarbonate and a cost-effective plate 21 made of polypropylene, wherein the structure of the plate 21, a sufficient stability can be ensured.
  • Polypropylene is preferably used for the plate 21.
  • the plate 21 is placed on the upper edge 7 of the frame 1.
  • the further contact surface 32 rests on the contact surface 8 (see Fig. 1 ) and the columns 9 engage in the holes 33 a.
  • a pipette tip 36 inserted from above into a hole 23 of the plate 21.
  • the pipette tip 36 has a widening 37 at the top, which prevents it from falling through the hole 23.
  • the plate 21 is loaded during the pressing of the approaches of a metering tool in the upper openings of eight pipette tips with a force of about 100 to 400 Newton, preferably 200 to 300, in particular about 240 Newton. Even with polypropylene version, the plate 21 withstands this load due to its structure and its support via circumferential contact surfaces 32 without adverse deflection. Also, the frame 1 is not overloaded even in polypropylene version here.
  • the shape of the columns 9 and the holes 33 and the play between them facilitate the placement of the plate 21 on the frame 1. Nevertheless, the plate 21 is securely held on the frame 1. Safe transport can be carried out by means of a gripping tool of a machine.
  • the gripping tool may comprise the frame 1 on the outsides of opposed side walls 2, 4 or 3, 5 at the waist 17. One Slipping of the gripping tool is avoided by the outwardly projecting upper projection 13 and the bottom 6.
  • edges 26 to 29 of the plate 21 are accessible from the outside and can be easily grasped with a gripping tool.
  • the gripping tool preferably engages the longer edges 28, 29, which are provided with the upwardly projecting gripping edge 30, 31.
  • a gripping edge may have further elements, such as apertures, depressions, elevation, etc., which enable a positive gripping, in particular by gripping arms.
  • the plate 21 can be gripped manually, in particular on the edges 28, 29 provided with the projecting gripping edge 30, 31.
  • the gripping edge 30, 31 protruding beyond the top of the pipette tips 36 prevents soiling of inserted pipette tips 36.
  • a lid 38 has a flat lid bottom 39 and lid side walls 40 to 43 projecting downwardly therefrom.
  • the opposite, short cover side walls 41, 42 each have a recess 44, 45.
  • the cover side walls 40 to 43 sit with their lower edge 46 on the step 14.
  • On their inner sides are guided on the positioning lugs 16.
  • the cover 38 covers a patch on the frame 1 plate 21 with inserted pipette tips 36.
  • the outer sides of the cover side walls 40 to 43 and the edge surface 15 are aligned with each other and can be used for the attachment of an adhesive tape that connects the lid 38 tightly with the frame 1 ,
  • the lid 38 is preferably made of a transparent material.
  • the lid 38 has at the top of its bottom 39 in the corner region upwardly projecting ribs 39.1 to 39.4. Furthermore, it has at the upper edges of its lid side walls 41, 43 recesses 41.1, 43.1. On the top of a lid 38, a frame 4 with its bottom 6 can be placed. The skirt 19 of the bottom 6 is guided inside the ribs 39.1 to 39.4. In the recesses 41.1, 43.1 cutting-edge separation tools 43.2 can be used to separate in a stack superimposed frame 4 and lid 38 from each other (see. Fig. 14 ).
  • the lid 38 is preferably made in one piece.
  • plastics are used.
  • it is injection molded.
  • the plastics polycarbonate (PC), polystyrene (PS), polypropylene (PP) or acrylonitrile-butadiene-styrene copolymers (ABS) can be used.
  • PC polycarbonate
  • PS polystyrene
  • PP polypropylene
  • ABS acrylonitrile-butadiene-styrene copolymers
  • Polycarbonate or polystyrene is preferably used, since these materials enable the production of a crystal-clear cover 38.
  • the carrier has a frame-shaped spacer 47.
  • This has four vertical spacer side walls 48 to 51, which are interconnected at the corners.
  • the spacer has a Intermediate bottom 52 with 24, 48, 96, 384 or 1536 through further holes 53, which have a matrix arrangement corresponding to the holes 23 of the plate 21.
  • the spacer 47 is preferably made in one piece. Preference is given to using plastics. Preferably, it is injection molded. But it can also be produced as a deep-drawn part.
  • plastics polypropylene (PP), polystyrene (PS), polycarbonate (PC), acrylonitrile-butadiene-styrene copolymers (ABS) or polystyrene (PS) can be used.
  • Polypropylene is preferably used, since it is particularly cost-effective.
  • Fig. 8 the spacer 47 is placed with its lower edge 54 on top of a plate 21 which is placed on a frame 1.
  • Fig. 9 is placed on the upper edge 55 of the spacer 47, a further plate 21 and thereon another spacer 47 and so on.
  • pipette tips 36 are guided laterally from the other holes 33 in the shelves below arranged spacer 47. This avoids misalignments of pipette tips 36 during automatic or manual stacking of filled plates 21.
  • When lifting the plate 21 prevents the intermediate bottom 52 that pipette tips 36 are taken from a plate 21 disposed thereunder.
  • To cover the arrangement can be placed on the top plate 21 loosely a lid 38 (see. Fig. 10 ).
EP10000090.0A 2009-01-23 2010-01-08 Support pour pointes de pipettes Active EP2210668B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE200910006511 DE102009006511B4 (de) 2009-01-23 2009-01-23 Träger für Pipettenspitzen

Publications (3)

Publication Number Publication Date
EP2210668A2 true EP2210668A2 (fr) 2010-07-28
EP2210668A3 EP2210668A3 (fr) 2012-10-31
EP2210668B1 EP2210668B1 (fr) 2019-02-20

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Family Applications (1)

Application Number Title Priority Date Filing Date
EP10000090.0A Active EP2210668B1 (fr) 2009-01-23 2010-01-08 Support pour pointes de pipettes

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EP (1) EP2210668B1 (fr)
DE (1) DE102009006511B4 (fr)

Cited By (6)

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DE202014100076U1 (de) 2014-01-09 2014-01-28 Tecan Trading Ag Abstandhalter für übereinander gestapelte Pipettenspitzen-Träger
EP2839880A1 (fr) * 2013-08-20 2015-02-25 Eppendorf Ag Support pour embouts de pipette
US9352324B2 (en) 2009-01-23 2016-05-31 Eppendorf Ag Carrier for pipette tips
EP3109642A1 (fr) 2015-06-25 2016-12-28 Roche Diagnostics GmbH Dispositif et procede permettant de manipuler des rateliers de pointes de pipette jetables dans un systeme d'automatisation de laboratoire et systeme d'automatisation de laboratoire
US9662654B2 (en) 2013-12-20 2017-05-30 Tecan Trading Ag Spacer for pipette tip carriers stacked one on top of another
EP4085258A4 (fr) * 2019-12-31 2023-06-14 Anatolia Tani Ve Biyoteknoloji Urunleri Arastirma Gelistirme Sanayi Ve Ticaret Anonim Sirketi Système de transport de cartouche réactive

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Publication number Priority date Publication date Assignee Title
CH709307A1 (de) 2014-02-26 2015-08-28 Tecan Trading Ag Transportwerkzeug zum Transportieren eines Laborartikels.
DE202014101440U1 (de) 2014-03-27 2014-04-03 Tecan Trading Ag Transportwerkzeug zum Transportieren eines Laborartikels
DE102015006731A1 (de) 2015-05-31 2016-12-01 Sarstedt Ag & Co. Pipettenspitzenverpackung
ES2911471T3 (es) 2018-12-14 2022-05-19 Eppendorf Ag Aparato automático de laboratorio para el tratamiento automático de muestras de laboratorio

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WO2000051899A1 (fr) 1999-03-05 2000-09-08 Rainin Instrument Co., Inc. Bloc de remplissage pour bac de pointes de pipettes et plaque de support amelioree
US6221317B1 (en) 1999-04-30 2001-04-24 Ccs Packard, Inc. Universal pipette tip box

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US9352324B2 (en) 2009-01-23 2016-05-31 Eppendorf Ag Carrier for pipette tips
EP2839880A1 (fr) * 2013-08-20 2015-02-25 Eppendorf Ag Support pour embouts de pipette
EP3643407A1 (fr) * 2013-08-20 2020-04-29 Eppendorf AG Support pour embouts de pipette
US9662654B2 (en) 2013-12-20 2017-05-30 Tecan Trading Ag Spacer for pipette tip carriers stacked one on top of another
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DE102009006511A1 (de) 2010-08-12
DE102009006511B4 (de) 2012-02-23
EP2210668B1 (fr) 2019-02-20
EP2210668A3 (fr) 2012-10-31

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