EP2205234A4 - METHODS AND COMPOUNDS FOR THE TREATMENT OF RETINOL RELATED DISEASES - Google Patents

METHODS AND COMPOUNDS FOR THE TREATMENT OF RETINOL RELATED DISEASES

Info

Publication number
EP2205234A4
EP2205234A4 EP08834564A EP08834564A EP2205234A4 EP 2205234 A4 EP2205234 A4 EP 2205234A4 EP 08834564 A EP08834564 A EP 08834564A EP 08834564 A EP08834564 A EP 08834564A EP 2205234 A4 EP2205234 A4 EP 2205234A4
Authority
EP
European Patent Office
Prior art keywords
compounds
methods
related diseases
retinol
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08834564A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP2205234A2 (en
Inventor
Nathan L Mata
Kim B Phan
Tam V Bui
Mustapha Haddach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Revision Therapeutics Inc
Original Assignee
Revision Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Revision Therapeutics Inc filed Critical Revision Therapeutics Inc
Publication of EP2205234A2 publication Critical patent/EP2205234A2/en
Publication of EP2205234A4 publication Critical patent/EP2205234A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP08834564A 2007-09-27 2008-09-16 METHODS AND COMPOUNDS FOR THE TREATMENT OF RETINOL RELATED DISEASES Withdrawn EP2205234A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97576507P 2007-09-27 2007-09-27
US98132207P 2007-10-19 2007-10-19
PCT/US2008/076499 WO2009042444A2 (en) 2007-09-27 2008-09-16 Methods and compounds for treating retinol-related diseases

Publications (2)

Publication Number Publication Date
EP2205234A2 EP2205234A2 (en) 2010-07-14
EP2205234A4 true EP2205234A4 (en) 2010-12-22

Family

ID=40512081

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08834564A Withdrawn EP2205234A4 (en) 2007-09-27 2008-09-16 METHODS AND COMPOUNDS FOR THE TREATMENT OF RETINOL RELATED DISEASES

Country Status (8)

Country Link
EP (1) EP2205234A4 (enrdf_load_stackoverflow)
JP (1) JP2010540541A (enrdf_load_stackoverflow)
KR (1) KR20100097098A (enrdf_load_stackoverflow)
CN (1) CN101873852A (enrdf_load_stackoverflow)
AU (1) AU2008305303A1 (enrdf_load_stackoverflow)
CA (1) CA2699773A1 (enrdf_load_stackoverflow)
IL (1) IL204728A0 (enrdf_load_stackoverflow)
WO (1) WO2009042444A2 (enrdf_load_stackoverflow)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5374377B2 (ja) * 2007-10-18 2013-12-25 武田薬品工業株式会社 複素環化合物
MX2011010694A (es) 2009-04-16 2011-10-21 Takeda Pharmaceutical Derivados de n-acil-n'-fenilpiperazina utiles (inter alia) para la profilaxis o tratamiento de diabetes.
WO2012071369A2 (en) * 2010-11-24 2012-05-31 The Trustees Of Columbia University In The City Of New York A non-retinoid rbp4 antagonist for treatment of age-related macular degeneration and stargardt disease
WO2012074038A1 (ja) * 2010-12-02 2012-06-07 第一三共株式会社 修飾１本鎖ポリヌクレオチド
US9333202B2 (en) 2012-05-01 2016-05-10 The Trustees Of Columbia University In The City Of New York Non-retinoid antagonists for treatment of age-related macular degeneration and stargardt disease
WO2014151936A1 (en) 2013-03-14 2014-09-25 The Trustees Of Columbia University In The City Of New York Octahydropyrrolopyrroles, their preparation and use
WO2014151959A1 (en) 2013-03-14 2014-09-25 The Trustees Of Columbia University In The City Of New York N-alkyl-2-phenoxyethanamines, their preparation and use
ES2705247T3 (es) 2013-03-14 2019-03-22 Univ Columbia 4-fenilpiperidinas, su preparación y uso
ES2700541T3 (es) 2013-03-14 2019-02-18 Univ Columbia Octahidrociclopentapirroles, su preparación y uso
BR112016025356B1 (pt) 2014-04-30 2023-04-18 The Trustees Of Columbia University In The City Of New York Compostos de 4-fenilpiperidinas substituídas, composições e seus usos
US9944596B2 (en) * 2014-10-24 2018-04-17 Takeda Pharmaceutical Company Limited Heterocyclic compound
MA53568A (fr) * 2014-10-24 2022-02-23 Takeda Pharmaceuticals Co Médicaments pour le traitement de maladies ophtalmiques
EP4142796A4 (en) * 2020-04-29 2024-06-26 Saliogen Therapeutics, Inc. COMPOSITIONS AND METHODS FOR TREATMENT OF HEREDITARY MACULAR DEGENERATION

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2526534A (en) * 1948-07-03 1950-10-17 Dow Chemical Co Di-(aryloxy)-methanes
US4255152A (en) * 1978-09-05 1981-03-10 Ciba-Geigy Corporation Process for the dyeing of hydrophobic fibres
WO2005092062A2 (en) * 2004-03-19 2005-10-06 Myriad Genetics, Inc. Compounds for neurodegenerative disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS577480A (en) * 1980-06-16 1982-01-14 Sankyo Co Ltd 4-alkoxy-6-phenoxymethyl-2-pyrone derivative
US7510710B2 (en) * 2004-01-08 2009-03-31 The Regents Of The University Of Colorado Compositions of UCP inhibitors, Fas antibody, a fatty acid metabolism inhibitor and/or a glucose metabolism inhibitor
WO2005116010A1 (en) * 2004-05-26 2005-12-08 Merck Frosst Canada Ltd. Ep4 receptor agonist, compositions and methods thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2526534A (en) * 1948-07-03 1950-10-17 Dow Chemical Co Di-(aryloxy)-methanes
US4255152A (en) * 1978-09-05 1981-03-10 Ciba-Geigy Corporation Process for the dyeing of hydrophobic fibres
WO2005092062A2 (en) * 2004-03-19 2005-10-06 Myriad Genetics, Inc. Compounds for neurodegenerative disorders

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
SANDHAM ET AL: "2-Cycloalkyl phenoxyacetic acid CRTh2 receptor antagonists", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, ELSEVIER SCIENCE, GB LNKD- DOI:10.1016/J.BMCL.2007.05.019, vol. 17, no. 15, 1 August 2007 (2007-08-01), pages 4347 - 4350, XP022144702, ISSN: 0960-894X *
ULVEN TROND ET AL: "Novel selective orally active CRTH2 antagonists for allergic inflammation developed from in silico derived hits", JOURNAL OF MEDICINAL CHEMISTRY, vol. 49, no. 23, November 2006 (2006-11-01), pages 6638 - 6641, XP002608837, ISSN: 0022-2623 *

Also Published As

Publication number Publication date
KR20100097098A (ko) 2010-09-02
IL204728A0 (en) 2010-11-30
AU2008305303A1 (en) 2009-04-02
CN101873852A (zh) 2010-10-27
JP2010540541A (ja) 2010-12-24
WO2009042444A2 (en) 2009-04-02
WO2009042444A3 (en) 2009-05-14
EP2205234A2 (en) 2010-07-14
CA2699773A1 (en) 2009-04-02

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Owner name: REVISION THERAPEUTICS, INC.

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