IL204728A0 - Methods and compounds for treating retinol-related diseases - Google Patents
Methods and compounds for treating retinol-related diseasesInfo
- Publication number
- IL204728A0 IL204728A0 IL204728A IL20472810A IL204728A0 IL 204728 A0 IL204728 A0 IL 204728A0 IL 204728 A IL204728 A IL 204728A IL 20472810 A IL20472810 A IL 20472810A IL 204728 A0 IL204728 A0 IL 204728A0
- Authority
- IL
- Israel
- Prior art keywords
- compounds
- methods
- related diseases
- retinol
- treating
- Prior art date
Links
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 title 2
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 229960003471 retinol Drugs 0.000 title 1
- 235000020944 retinol Nutrition 0.000 title 1
- 239000011607 retinol Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97576507P | 2007-09-27 | 2007-09-27 | |
| US98132207P | 2007-10-19 | 2007-10-19 | |
| PCT/US2008/076499 WO2009042444A2 (en) | 2007-09-27 | 2008-09-16 | Methods and compounds for treating retinol-related diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL204728A0 true IL204728A0 (en) | 2010-11-30 |
Family
ID=40512081
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL204728A IL204728A0 (en) | 2007-09-27 | 2010-03-25 | Methods and compounds for treating retinol-related diseases |
Country Status (8)
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2202223B1 (en) * | 2007-10-18 | 2017-01-25 | Takeda Pharmaceutical Company Limited | Heterocyclic compound as blood rbp4 lowering agent |
| US8853215B2 (en) | 2009-04-16 | 2014-10-07 | Takeda Pharmaceutical Company Limited | Derivatives of N-acyl-N′-phenylpiperazine useful (inter alia) for the prophylaxis or treatment of diabetes |
| JP5951625B2 (ja) * | 2010-11-24 | 2016-07-13 | ザ・トラスティーズ・オブ・コランビア・ユニバーシティー・イン・ザ・シティー・オブ・ニューヨークＴｈｅ Ｔｒｕｓｔｅｅｓ Ｏｆ Ｃｏｌｕｍｂｉａ Ｕｎｉｖｅｒｓｉｔｙ Ｉｎ Ｔｈｅ Ｃｉｔｙ Ｏｆ Ｎｅｗ Ｙｏｒｋ | 加齢性黄斑変性症およびシュタルガルト病の処置のための非レチノイドｒｂｐ４アンタゴニスト |
| RU2013129999A (ru) * | 2010-12-02 | 2015-01-10 | Дайити Санкио Компани, Лимитед | Модифицированный одноцепочечный полинуклеотид |
| US9333202B2 (en) | 2012-05-01 | 2016-05-10 | The Trustees Of Columbia University In The City Of New York | Non-retinoid antagonists for treatment of age-related macular degeneration and stargardt disease |
| US9938291B2 (en) | 2013-03-14 | 2018-04-10 | The Trustess Of Columbia University In The City Of New York | N-alkyl-2-phenoxyethanamines, their preparation and use |
| WO2014152018A1 (en) | 2013-03-14 | 2014-09-25 | The Trustees Of Columbia University In The City Of New York | Octahydrocyclopentapyrroles, their preparation and use |
| WO2014151936A1 (en) | 2013-03-14 | 2014-09-25 | The Trustees Of Columbia University In The City Of New York | Octahydropyrrolopyrroles, their preparation and use |
| ES2705247T3 (es) | 2013-03-14 | 2019-03-22 | Univ Columbia | 4-fenilpiperidinas, su preparación y uso |
| EP4036094A1 (en) | 2014-04-30 | 2022-08-03 | The Trustees of Columbia University in the City of New York | Substituted 4-phenylpiperidines, their preparation and use |
| MA39688B1 (fr) * | 2014-10-24 | 2021-02-26 | Takeda Pharmaceuticals Co | Composés hétéroaryle pour le traitement de maladies ophtalmiques |
| JP6646586B2 (ja) * | 2014-10-24 | 2020-02-14 | 武田薬品工業株式会社 | 複素環化合物 |
| AU2021265838A1 (en) * | 2020-04-29 | 2022-10-20 | Saliogen Therapeutics, Inc. | Compositions and methods for treatment of inherited macular degeneration |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2526534A (en) * | 1948-07-03 | 1950-10-17 | Dow Chemical Co | Di-(aryloxy)-methanes |
| US4255152A (en) * | 1978-09-05 | 1981-03-10 | Ciba-Geigy Corporation | Process for the dyeing of hydrophobic fibres |
| JPS577480A (en) * | 1980-06-16 | 1982-01-14 | Sankyo Co Ltd | 4-alkoxy-6-phenoxymethyl-2-pyrone derivative |
| US7510710B2 (en) * | 2004-01-08 | 2009-03-31 | The Regents Of The University Of Colorado | Compositions of UCP inhibitors, Fas antibody, a fatty acid metabolism inhibitor and/or a glucose metabolism inhibitor |
| US20090155903A1 (en) * | 2004-03-19 | 2009-06-18 | Myriad Genetics, Incorporated | Pharmaceutical composition and method |
| WO2005116010A1 (en) * | 2004-05-26 | 2005-12-08 | Merck Frosst Canada Ltd. | Ep4 receptor agonist, compositions and methods thereof |
-
2008
- 2008-09-16 JP JP2010527024A patent/JP2010540541A/ja active Pending
- 2008-09-16 CN CN200880107835A patent/CN101873852A/zh active Pending
- 2008-09-16 EP EP08834564A patent/EP2205234A4/en not_active Withdrawn
- 2008-09-16 WO PCT/US2008/076499 patent/WO2009042444A2/en active Application Filing
- 2008-09-16 KR KR1020107009129A patent/KR20100097098A/ko not_active Withdrawn
- 2008-09-16 AU AU2008305303A patent/AU2008305303A1/en not_active Abandoned
- 2008-09-16 CA CA2699773A patent/CA2699773A1/en not_active Abandoned
-
2010
- 2010-03-25 IL IL204728A patent/IL204728A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2010540541A (ja) | 2010-12-24 |
| WO2009042444A2 (en) | 2009-04-02 |
| CN101873852A (zh) | 2010-10-27 |
| EP2205234A2 (en) | 2010-07-14 |
| EP2205234A4 (en) | 2010-12-22 |
| WO2009042444A3 (en) | 2009-05-14 |
| KR20100097098A (ko) | 2010-09-02 |
| CA2699773A1 (en) | 2009-04-02 |
| AU2008305303A1 (en) | 2009-04-02 |
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