EP2205234A4 - Verfahren und verbindungen zur behandlung retinolbedingter erkrankungen - Google Patents

Verfahren und verbindungen zur behandlung retinolbedingter erkrankungen

Info

Publication number
EP2205234A4
EP2205234A4 EP08834564A EP08834564A EP2205234A4 EP 2205234 A4 EP2205234 A4 EP 2205234A4 EP 08834564 A EP08834564 A EP 08834564A EP 08834564 A EP08834564 A EP 08834564A EP 2205234 A4 EP2205234 A4 EP 2205234A4
Authority
EP
European Patent Office
Prior art keywords
compounds
methods
related diseases
retinol
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08834564A
Other languages
English (en)
French (fr)
Other versions
EP2205234A2 (de
Inventor
Nathan L Mata
Kim B Phan
Tam V Bui
Mustapha Haddach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Revision Therapeutics Inc
Original Assignee
Revision Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Revision Therapeutics Inc filed Critical Revision Therapeutics Inc
Publication of EP2205234A2 publication Critical patent/EP2205234A2/de
Publication of EP2205234A4 publication Critical patent/EP2205234A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EP08834564A 2007-09-27 2008-09-16 Verfahren und verbindungen zur behandlung retinolbedingter erkrankungen Withdrawn EP2205234A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US97576507P 2007-09-27 2007-09-27
US98132207P 2007-10-19 2007-10-19
PCT/US2008/076499 WO2009042444A2 (en) 2007-09-27 2008-09-16 Methods and compounds for treating retinol-related diseases

Publications (2)

Publication Number Publication Date
EP2205234A2 EP2205234A2 (de) 2010-07-14
EP2205234A4 true EP2205234A4 (de) 2010-12-22

Family

ID=40512081

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08834564A Withdrawn EP2205234A4 (de) 2007-09-27 2008-09-16 Verfahren und verbindungen zur behandlung retinolbedingter erkrankungen

Country Status (8)

Country Link
EP (1) EP2205234A4 (de)
JP (1) JP2010540541A (de)
KR (1) KR20100097098A (de)
CN (1) CN101873852A (de)
AU (1) AU2008305303A1 (de)
CA (1) CA2699773A1 (de)
IL (1) IL204728A0 (de)
WO (1) WO2009042444A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009051244A1 (ja) 2007-10-18 2009-04-23 Takeda Pharmaceutical Company Limited 複素環化合物
RU2011146363A (ru) 2009-04-16 2013-05-27 Такеда Фармасьютикал Компани Лимитед Производные n-ацил-n-фенилпиперазина, используемые (кроме того) для профилактики или лечения диабета
EP2642998B1 (de) * 2010-11-24 2020-09-16 The Trustees of Columbia University in the City of New York Non-retinoider rbp4-antagonist zur behandlung von altersbedingter makuladegeneration und morbus stargardt
KR20140001224A (ko) * 2010-12-02 2014-01-06 다이이찌 산쿄 가부시키가이샤 수식 1 개 사슬 폴리뉴클레오티드
WO2013166037A1 (en) 2012-05-01 2013-11-07 The Trustees Of Columbia University In The City Of New York Non-retinoid antagonists for treatment of eye disorders
EP2968303B1 (de) 2013-03-14 2018-07-04 The Trustees of Columbia University in the City of New York Octahydrocyclopentapyrrole und deren herstellung und verwendung
WO2014151936A1 (en) 2013-03-14 2014-09-25 The Trustees Of Columbia University In The City Of New York Octahydropyrrolopyrroles, their preparation and use
EP2968304B1 (de) 2013-03-14 2018-10-10 The Trustees of Columbia University in the City of New York 4-phenylpiperidine, deren herstellung und verwendung
WO2014151959A1 (en) 2013-03-14 2014-09-25 The Trustees Of Columbia University In The City Of New York N-alkyl-2-phenoxyethanamines, their preparation and use
DK3137168T3 (da) 2014-04-30 2022-03-21 Univ Columbia Substituerede 4-phenylpiperidiner, deres fremstilling og anvendelse
US9944596B2 (en) * 2014-10-24 2018-04-17 Takeda Pharmaceutical Company Limited Heterocyclic compound
TN2017000097A1 (en) 2014-10-24 2018-07-04 Takeda Pharmaceuticals Co Heterocyclic compound

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2526534A (en) * 1948-07-03 1950-10-17 Dow Chemical Co Di-(aryloxy)-methanes
US4255152A (en) * 1978-09-05 1981-03-10 Ciba-Geigy Corporation Process for the dyeing of hydrophobic fibres
WO2005092062A2 (en) * 2004-03-19 2005-10-06 Myriad Genetics, Inc. Compounds for neurodegenerative disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS577480A (en) * 1980-06-16 1982-01-14 Sankyo Co Ltd 4-alkoxy-6-phenoxymethyl-2-pyrone derivative
WO2005070126A2 (en) * 2004-01-08 2005-08-04 The Regents Of The University Of Colorado Methods and compositions for treating human diseases and wounds with ucp and fas inhibitors
WO2005116010A1 (en) * 2004-05-26 2005-12-08 Merck Frosst Canada Ltd. Ep4 receptor agonist, compositions and methods thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2526534A (en) * 1948-07-03 1950-10-17 Dow Chemical Co Di-(aryloxy)-methanes
US4255152A (en) * 1978-09-05 1981-03-10 Ciba-Geigy Corporation Process for the dyeing of hydrophobic fibres
WO2005092062A2 (en) * 2004-03-19 2005-10-06 Myriad Genetics, Inc. Compounds for neurodegenerative disorders

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
SANDHAM ET AL: "2-Cycloalkyl phenoxyacetic acid CRTh2 receptor antagonists", BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, PERGAMON, ELSEVIER SCIENCE, GB LNKD- DOI:10.1016/J.BMCL.2007.05.019, vol. 17, no. 15, 1 August 2007 (2007-08-01), pages 4347 - 4350, XP022144702, ISSN: 0960-894X *
ULVEN TROND ET AL: "Novel selective orally active CRTH2 antagonists for allergic inflammation developed from in silico derived hits", JOURNAL OF MEDICINAL CHEMISTRY, vol. 49, no. 23, November 2006 (2006-11-01), pages 6638 - 6641, XP002608837, ISSN: 0022-2623 *

Also Published As

Publication number Publication date
CA2699773A1 (en) 2009-04-02
EP2205234A2 (de) 2010-07-14
AU2008305303A1 (en) 2009-04-02
CN101873852A (zh) 2010-10-27
WO2009042444A2 (en) 2009-04-02
WO2009042444A3 (en) 2009-05-14
KR20100097098A (ko) 2010-09-02
JP2010540541A (ja) 2010-12-24
IL204728A0 (en) 2010-11-30

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Legal Events

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RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: REVISION THERAPEUTICS, INC.

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Effective date: 20101119

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