EP2176406A4 - Compositions et procédés de traitement du cancer - Google Patents

Compositions et procédés de traitement du cancer

Info

Publication number
EP2176406A4
EP2176406A4 EP08776735A EP08776735A EP2176406A4 EP 2176406 A4 EP2176406 A4 EP 2176406A4 EP 08776735 A EP08776735 A EP 08776735A EP 08776735 A EP08776735 A EP 08776735A EP 2176406 A4 EP2176406 A4 EP 2176406A4
Authority
EP
European Patent Office
Prior art keywords
compositions
methods
treating cancer
cancer
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08776735A
Other languages
German (de)
English (en)
Other versions
EP2176406A1 (fr
Inventor
Akira Togashi
Ryutaro Tobita
Yuka Ishizaki
Akiko Konuma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Oncotherapy Science Inc
Original Assignee
Oncotherapy Science Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncotherapy Science Inc filed Critical Oncotherapy Science Inc
Publication of EP2176406A1 publication Critical patent/EP2176406A1/fr
Publication of EP2176406A4 publication Critical patent/EP2176406A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
EP08776735A 2007-06-27 2008-06-26 Compositions et procédés de traitement du cancer Withdrawn EP2176406A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93761607P 2007-06-27 2007-06-27
PCT/JP2008/001665 WO2009001562A1 (fr) 2007-06-27 2008-06-26 Compositions et procédés de traitement du cancer

Publications (2)

Publication Number Publication Date
EP2176406A1 EP2176406A1 (fr) 2010-04-21
EP2176406A4 true EP2176406A4 (fr) 2011-10-19

Family

ID=40185387

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08776735A Withdrawn EP2176406A4 (fr) 2007-06-27 2008-06-26 Compositions et procédés de traitement du cancer

Country Status (10)

Country Link
US (1) US20100273855A1 (fr)
EP (1) EP2176406A4 (fr)
JP (1) JP2010531133A (fr)
KR (1) KR20100031133A (fr)
CN (1) CN101796184A (fr)
BR (1) BRPI0812932A2 (fr)
CA (1) CA2691510A1 (fr)
RU (1) RU2010102531A (fr)
TW (1) TW200908998A (fr)
WO (1) WO2009001562A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1668354A2 (fr) * 2003-09-24 2006-06-14 Oncotherapy Science, Inc. Methode de diagnostic du cancer du sein
EP2295570A1 (fr) * 2005-07-27 2011-03-16 Oncotherapy Science, Inc. Procédé de diagnostic du cancer pulmonaire à petites cellules
TW201000119A (en) * 2008-06-10 2010-01-01 Oncotherapy Science Inc MYBL2 epitope peptides and vaccines containing the same
TW201200525A (en) * 2009-12-04 2012-01-01 Oncotherapy Science Inc MYBL2 peptides and vaccines containing the same
US10092634B2 (en) * 2012-09-11 2018-10-09 Oncotherapy Science, Inc. UBE2T peptides and vaccines containing the same
CN107881241B (zh) * 2017-12-27 2020-09-01 青岛泱深生物医药有限公司 基因标志物在乳腺癌诊断和治疗中的应用
CN109136376B (zh) * 2018-05-21 2021-09-21 中国医科大学附属第四医院 一种膀胱癌相关环状RNA的应用和siRNA及其用途
CN110870871B (zh) * 2018-09-04 2021-09-07 澳门科技大学 用于治疗癌症的方法和药物组合物
CN111228502A (zh) * 2020-03-10 2020-06-05 新疆医科大学第三附属医院 人ube2s基因的用途及相关产品
CN111544595B (zh) * 2020-05-29 2021-10-26 中山大学 泛素结合酶e2抑制剂和溶瘤病毒在制备抗肿瘤药物的应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003070917A2 (fr) * 2002-02-20 2003-08-28 Sirna Therapeutics, Inc. Inhibition induite par l'interference de l'arn de l'expression genique myc et myb ou de l'expression de genes intervenant dans les voies myc et myb faisant appel a un acide nucleique interferant court (sina)
WO2004061423A2 (fr) * 2003-01-06 2004-07-22 Wyeth Compositions et procede permettant de diagnostiquer et de traiter les cancers du colon
WO2005089735A2 (fr) * 2004-03-24 2005-09-29 Oncotherapy Science, Inc. Compositions et procédés servant à traiter un cancer des poumons
WO2006039582A2 (fr) * 2004-09-30 2006-04-13 The Regents Of The University Of California Compositions et methodes de diagnostic et de traitement du cancer du cerveau et d'identification de cellules souches neuronales

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7514084B2 (en) * 2002-09-12 2009-04-07 Oncotherapy Science, Inc. KDR peptides and vaccines comprising the same
US20050260639A1 (en) * 2002-09-30 2005-11-24 Oncotherapy Science, Inc. Method for diagnosing pancreatic cancer
WO2004031410A2 (fr) * 2002-09-30 2004-04-15 Oncotherapy Science, Inc. Methode permettant de diagnostiquer des seminomes du testicule
US20060024692A1 (en) * 2002-09-30 2006-02-02 Oncotherapy Science, Inc. Method for diagnosing non-small cell lung cancers
US20050259483A1 (en) * 2002-09-30 2005-11-24 Oncotherapy Science, Inc. Genes and polypeptides relating to prostate cancers
EP1668354A2 (fr) * 2003-09-24 2006-06-14 Oncotherapy Science, Inc. Methode de diagnostic du cancer du sein
US20070202109A1 (en) * 2003-09-24 2007-08-30 Oncotherapy Science, Inc. Method Of Diagnosing Breast Cancer
WO2005090572A2 (fr) * 2004-03-24 2005-09-29 Oncotherapy Science, Inc. Compositions et procédés servant à traiter un cancer du pancréas
JP2005304497A (ja) * 2004-03-25 2005-11-04 Joji Inasawa 特定の癌関連遺伝子を用いる癌の検出方法及び癌の抑制方法
WO2005116204A1 (fr) * 2004-05-11 2005-12-08 Rnai Co., Ltd. Polynucléotide provoquant l'interférence rna et procédé de regulation d'expression génétique avec l’usage de ce dernier
EP2011885B1 (fr) * 2005-02-10 2015-04-22 Oncotherapy Science, Inc. Procédé de diagnostic de cancer de la vessie
EP2295570A1 (fr) * 2005-07-27 2011-03-16 Oncotherapy Science, Inc. Procédé de diagnostic du cancer pulmonaire à petites cellules
JP5150909B2 (ja) * 2005-07-27 2013-02-27 オンコセラピー・サイエンス株式会社 食道癌を診断する方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003070917A2 (fr) * 2002-02-20 2003-08-28 Sirna Therapeutics, Inc. Inhibition induite par l'interference de l'arn de l'expression genique myc et myb ou de l'expression de genes intervenant dans les voies myc et myb faisant appel a un acide nucleique interferant court (sina)
WO2004061423A2 (fr) * 2003-01-06 2004-07-22 Wyeth Compositions et procede permettant de diagnostiquer et de traiter les cancers du colon
WO2005089735A2 (fr) * 2004-03-24 2005-09-29 Oncotherapy Science, Inc. Compositions et procédés servant à traiter un cancer des poumons
WO2006039582A2 (fr) * 2004-09-30 2006-04-13 The Regents Of The University Of California Compositions et methodes de diagnostic et de traitement du cancer du cerveau et d'identification de cellules souches neuronales

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
GARCIA P ET AL: "The transcription factor B-Myb is essential for S-phase progression and genomic stability in diploid and polyploid megakaryocytes", JOURNAL OF CELL SCIENCE, vol. 119, no. 8, 15 April 2006 (2006-04-15), pages 1483 - 1493, XP002626888, ISSN: 0021-9533, DOI: 10.1242/JCS.02870 *
LIU D X ET AL: "B-myb and C-myb play required roles in neuronal apoptosis evoked by nerve growth factor deprivation and DNA damage", JOURNAL OF NEUROSCIENCE, vol. 24, no. 40, 6 October 2004 (2004-10-06), pages 8720 - 8725, XP002627470, ISSN: 0270-6474, DOI: 10.1523/JNEUROSCI.1821-04.2004 *
NAKAJIMA TOMOAKI ET AL: "B-MYB promotes the growth of hepatocellular carcinoma cells through activation of CDC2 and CCNA2", HEPATOLOGY, vol. 44, no. 4, Suppl. 1, October 2006 (2006-10-01), & 57TH ANNUAL MEETING OF THE AMERICAN-ASSOCIATION-FOR-THE-STUDY-OF-LIVE R-DISEASES; BOSTON, MA, USA; OCTOBER 27 -31, 2006, pages 531A - 532A, XP002626887, ISSN: 0270-9139 *
NAKATA YUJI ET AL: "c-Myb contributes to G2/M cell cycle transition in human hematopoietic cells by direct regulation of cyclin B1 expression.", MOLECULAR AND CELLULAR BIOLOGY, vol. 27, no. 6, 22 January 2007 (2007-01-22), pages 2048 - 2058, XP002626890, ISSN: 0270-7306 *
NAKATA YUJI ET AL: "Myb Family Transcription Factors Contribute to G2/M Cell Cycle Transition in Normal and Malignant Hematopoietic Cells by Direct Regulation of Cyclin B1 Expression (Abstract 1115)", BLOOD, vol. 108, no. 11, November 2006 (2006-11-01), & 48TH ANNUAL MEETING OF THE AMERICAN-SOCIETY-OF-HEMATOLOGY; ORLANDO, FL, USA; DECEMBER 09 -12, 2006, XP002626928, Retrieved from the Internet <URL:http://abstracts.hematologylibrary.org/cgi/content/abstract/108/11/1115?maxtoshow=&hits=10&RESULTFORMAT=&fulltext=Yuji+Nakata&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT> [retrieved on 20110308] *
SANTILLI G ET AL: "Temperature-dependent modification and activation of B-MYB: Implications for cell survival", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 280, no. 16, 22 April 2005 (2005-04-22), AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY INC. US, pages 15628 - 15634, XP002626889, DOI: 10.1074/JBC.M411747200 *
See also references of WO2009001562A1 *
ZHU WENCHENG ET AL: "E2Fs link the control of G1/S and G2/M transcription.", THE EMBO JOURNAL, vol. 23, no. 23, 24 November 2004 (2004-11-24), pages 4615 - 4626, XP002626891, ISSN: 0261-4189 *

Also Published As

Publication number Publication date
KR20100031133A (ko) 2010-03-19
EP2176406A1 (fr) 2010-04-21
CN101796184A (zh) 2010-08-04
BRPI0812932A2 (pt) 2014-12-09
TW200908998A (en) 2009-03-01
JP2010531133A (ja) 2010-09-24
RU2010102531A (ru) 2011-08-10
US20100273855A1 (en) 2010-10-28
CA2691510A1 (fr) 2008-12-31
WO2009001562A1 (fr) 2008-12-31

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Ipc: A61K 31/7105 20060101ALI20110908BHEP

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