PL2155188T3 - Sposoby i kompozycje do leczenia nawrotowego raka - Google Patents
Sposoby i kompozycje do leczenia nawrotowego rakaInfo
- Publication number
- PL2155188T3 PL2155188T3 PL08768111T PL08768111T PL2155188T3 PL 2155188 T3 PL2155188 T3 PL 2155188T3 PL 08768111 T PL08768111 T PL 08768111T PL 08768111 T PL08768111 T PL 08768111T PL 2155188 T3 PL2155188 T3 PL 2155188T3
- Authority
- PL
- Poland
- Prior art keywords
- compositions
- methods
- recurrent cancer
- treating recurrent
- treating
- Prior art date
Links
- 206010038111 Recurrent cancer Diseases 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/282—Platinum compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/643—Albumins, e.g. HSA, BSA, ovalbumin or a Keyhole Limpet Hemocyanin [KHL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
- A61K47/6927—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores
- A61K47/6929—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a solid microparticle having no hollow or gas-filled cores the form being a nanoparticle, e.g. an immuno-nanoparticle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Nanotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Inorganic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US93275007P | 2007-06-01 | 2007-06-01 | |
| PCT/US2008/007024 WO2008150532A1 (en) | 2007-06-01 | 2008-06-02 | Methods and compositions for treating recurrent cancer |
| EP08768111.0A EP2155188B1 (en) | 2007-06-01 | 2008-06-02 | Methods and compositions for treating recurrent cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2155188T3 true PL2155188T3 (pl) | 2014-03-31 |
Family
ID=39733105
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL08768111T PL2155188T3 (pl) | 2007-06-01 | 2008-06-02 | Sposoby i kompozycje do leczenia nawrotowego raka |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US8927019B2 (pl) |
| EP (1) | EP2155188B1 (pl) |
| JP (3) | JP5579057B2 (pl) |
| AU (1) | AU2008260447B2 (pl) |
| CA (1) | CA2689914C (pl) |
| DK (1) | DK2155188T3 (pl) |
| ES (1) | ES2435452T3 (pl) |
| HR (1) | HRP20131142T1 (pl) |
| PL (1) | PL2155188T3 (pl) |
| PT (1) | PT2155188E (pl) |
| WO (1) | WO2008150532A1 (pl) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5439686A (en) * | 1993-02-22 | 1995-08-08 | Vivorx Pharmaceuticals, Inc. | Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor |
| US8853260B2 (en) | 1997-06-27 | 2014-10-07 | Abraxis Bioscience, Llc | Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
| US20030199425A1 (en) * | 1997-06-27 | 2003-10-23 | Desai Neil P. | Compositions and methods for treatment of hyperplasia |
| LT1585548T (lt) | 2002-12-09 | 2018-09-25 | Abraxis Bioscience, Llc | Farmakologinių agentų kompozicijos ir įvedimo būdai |
| BRPI0607809A2 (pt) | 2005-02-18 | 2009-06-13 | Abraxis Bioscience Inc | uso de uma composição compreendendo nanopartìculas, composição e kit |
| US8735394B2 (en) * | 2005-02-18 | 2014-05-27 | Abraxis Bioscience, Llc | Combinations and modes of administration of therapeutic agents and combination therapy |
| SI3311805T1 (sl) | 2005-08-31 | 2020-07-31 | Abraxis Bioscience, Llc | Sestave, ki zajemajo slabo vodotopne farmacevtske učinkovine in antimikrobna sredstva |
| ES2700074T3 (es) | 2006-12-14 | 2019-02-13 | Abraxis Bioscience Llc | Terapia para el cáncer de mama sobre la base del estado de los receptores hormonales con nanopartículas que comprenden taxano |
| SI2131821T1 (sl) | 2007-03-07 | 2018-11-30 | Abraxis Bioscience, Llc | Nanodelci, ki zajemajo rapamicin in albumin kot sredstvo proti raku |
| CA2686736A1 (en) * | 2007-05-03 | 2008-11-13 | Abraxis Bioscience, Llc | Nanoparticle compositions comprising rapamycin for treating pulmonary hypertension |
| WO2008150532A1 (en) | 2007-06-01 | 2008-12-11 | Abraxis Bioscience, Llc | Methods and compositions for treating recurrent cancer |
| AU2009234127B2 (en) * | 2008-04-10 | 2015-04-30 | Abraxis Bioscience, Llc | Compositions of hydrophobic taxane derivatives and uses thereof |
| ES2764100T3 (es) | 2009-04-15 | 2020-06-02 | Abraxis Bioscience Llc | Composiciones de nanopartículas exentas de priones y métodos |
| CA2774550A1 (en) * | 2009-09-18 | 2011-03-24 | Abraxis Bioscience, Llc | Use of the sparc microenvironment signature in the treatment of cancer |
| LT2552438T (lt) | 2010-03-26 | 2016-09-26 | Abraxis Bioscience, Llc | Hepatoceliulinės karcinomos gydymo būdai |
| MX364637B (es) | 2010-03-29 | 2019-05-03 | Abraxis Bioscience Llc Star | Platino y nanopartículas que incluyen placlitaxel/albúmina para usarse en el trartamiento de nsclc. |
| MX369728B (es) | 2010-03-29 | 2019-11-20 | Abraxis Bioscience Llc | Métodos para mejorar suministro de fármacos y efectividad de agentes terapéuticos. |
| KR20130086546A (ko) | 2010-06-03 | 2013-08-02 | 아브락시스 바이오사이언스, 엘엘씨 | 암 치료에 있어 ｓｐａｒｃ 미세환경 시그니처의 용도 |
| CA2801645A1 (en) | 2010-06-04 | 2011-12-08 | Abraxis Bioscience, Llc | Use of nanoparticules comprising a taxane and an albumin in the treatment of pancreatic cancer |
| US9061014B2 (en) | 2011-04-28 | 2015-06-23 | Abraxis Bioscience, Llc | Intravascular delivery of nanoparticle compositions and uses thereof |
| ME03532B (me) | 2011-12-14 | 2020-04-20 | Abraxis Bioscience Llc | Upotreba polimernih ekscipijenata za liofilizaciju ili zamrzavanje parтikula |
| KR102165348B1 (ko) * | 2012-05-09 | 2020-10-14 | 캔텍스 파마슈티칼즈, 인크. | 골수억제의 치료 |
| US9149455B2 (en) | 2012-11-09 | 2015-10-06 | Abraxis Bioscience, Llc | Methods of treating melanoma |
| US9511046B2 (en) | 2013-01-11 | 2016-12-06 | Abraxis Bioscience, Llc | Methods of treating pancreatic cancer |
| ES2804323T3 (es) | 2013-03-12 | 2021-02-05 | Abraxis Bioscience Llc | Procedimientos de tratamiento de cáncer de pulmón |
| CN110934852A (zh) | 2013-03-14 | 2020-03-31 | 阿布拉科斯生物科学有限公司 | 治疗膀胱癌的方法 |
| WO2016089873A1 (en) | 2014-12-02 | 2016-06-09 | Celgene Corporation | Combination therapies |
| EP3258941A4 (en) | 2015-02-17 | 2018-09-26 | Cantex Pharmaceuticals, Inc. | Treatment of cancers and hematopoietic stem cell disorders privileged by cxcl12-cxcr4 interaction |
| US10527604B1 (en) | 2015-03-05 | 2020-01-07 | Abraxis Bioscience, Llc | Methods of assessing suitability of use of pharmaceutical compositions of albumin and paclitaxel |
| US10705070B1 (en) | 2015-03-05 | 2020-07-07 | Abraxis Bioscience, Llc | Methods of assessing suitability of use of pharmaceutical compositions of albumin and poorly water soluble drug |
| RS66503B1 (sr) | 2015-06-29 | 2025-03-31 | Abraxis Bioscience Llc | Nanočestice koje sadrže sirolimus i albumin za upotrebu u lečenju tumora epitelioidnih ćelija |
| JP6856631B2 (ja) | 2015-09-16 | 2021-04-07 | ディーエフビー ソリア リミテッド ライアビリティ カンパニー | 薬物ナノ粒子の送達およびその使用法 |
| CN105412024B (zh) | 2015-12-14 | 2018-03-30 | 广州帝奇医药技术有限公司 | 靶向疏水性抗肿瘤药物纳米制剂及其制备方法 |
| CA3010568C (en) * | 2016-01-27 | 2023-10-17 | Instar Technologies A.S. | Oromucosal nanofiber carriers for therapeutic treatment |
| CN108700566A (zh) | 2016-02-19 | 2018-10-23 | 河谷控股Ip有限责任公司 | 免疫原性调节的方法 |
| BR112018068986B1 (pt) * | 2016-03-18 | 2023-03-21 | Christopher Brian Reid | Composição para reduzir a expressão oncógena de uma célula, tecido ou órgão de um indivíduo |
| CN110461311A (zh) * | 2016-08-26 | 2019-11-15 | 奥野哲治 | 微细纳米化药剂及其应用 |
| CA3056395C (en) | 2017-03-15 | 2022-06-28 | Dfb Soria, Llc | Topical therapy for the treatment of skin malignancies using nanoparticles of taxanes |
| US11497726B2 (en) | 2018-03-16 | 2022-11-15 | Dfb Soria, Ll. | Topical therapy for the treatment of cervical intraepithelial neoplasia (CIN) and cervical cancer using nanoparticles of taxanes |
| JP7534957B2 (ja) | 2018-03-20 | 2024-08-15 | アブラクシス バイオサイエンス， エルエルシー | ｍＴＯＲ阻害剤およびアルブミンのナノ粒子の投与を介して中枢神経系障害を処置する方法 |
| US12324807B2 (en) | 2018-06-01 | 2025-06-10 | Cornell University | Combination therapy for PI3K-associated disease or disorder |
| JP2022553426A (ja) | 2019-10-28 | 2022-12-22 | アブラクシス バイオサイエンス， エルエルシー | アルブミンおよびラパマイシンの医薬組成物 |
| WO2023070023A1 (en) * | 2021-10-21 | 2023-04-27 | Faeth Therapeutics, Inc. | Combination therapy for pik3ca-associated diseases or disorders |
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-
2008
- 2008-06-02 WO PCT/US2008/007024 patent/WO2008150532A1/en not_active Ceased
- 2008-06-02 PL PL08768111T patent/PL2155188T3/pl unknown
- 2008-06-02 DK DK08768111.0T patent/DK2155188T3/da active
- 2008-06-02 CA CA2689914A patent/CA2689914C/en active Active
- 2008-06-02 HR HRP20131142AT patent/HRP20131142T1/hr unknown
- 2008-06-02 US US12/600,991 patent/US8927019B2/en active Active
- 2008-06-02 ES ES08768111T patent/ES2435452T3/es active Active
- 2008-06-02 JP JP2010510376A patent/JP5579057B2/ja active Active
- 2008-06-02 PT PT87681110T patent/PT2155188E/pt unknown
- 2008-06-02 AU AU2008260447A patent/AU2008260447B2/en active Active
- 2008-06-02 EP EP08768111.0A patent/EP2155188B1/en active Active
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2013
- 2013-02-28 US US13/781,482 patent/US20140017316A1/en not_active Abandoned
-
2014
- 2014-07-08 JP JP2014140474A patent/JP2014185186A/ja active Pending
- 2014-11-21 US US14/550,509 patent/US20160158365A9/en not_active Abandoned
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2016
- 2016-07-07 JP JP2016134757A patent/JP2016172777A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US20160158365A9 (en) | 2016-06-09 |
| CA2689914A1 (en) | 2008-12-11 |
| HRP20131142T1 (hr) | 2014-01-03 |
| HK1140944A1 (en) | 2010-10-29 |
| US20150079181A1 (en) | 2015-03-19 |
| EP2155188A1 (en) | 2010-02-24 |
| CA2689914C (en) | 2016-08-16 |
| US20100215751A1 (en) | 2010-08-26 |
| US20140017316A1 (en) | 2014-01-16 |
| JP2010529025A (ja) | 2010-08-26 |
| US8927019B2 (en) | 2015-01-06 |
| DK2155188T3 (da) | 2013-11-04 |
| ES2435452T3 (es) | 2013-12-19 |
| JP2014185186A (ja) | 2014-10-02 |
| PT2155188E (pt) | 2013-12-19 |
| WO2008150532A1 (en) | 2008-12-11 |
| AU2008260447A1 (en) | 2008-12-11 |
| AU2008260447B2 (en) | 2013-10-10 |
| JP2016172777A (ja) | 2016-09-29 |
| EP2155188B1 (en) | 2013-10-09 |
| JP5579057B2 (ja) | 2014-08-27 |
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