EP2154081A1 - Dispositif de fermeture pour récipients de médicaments et similaires, incluant un réceptacle temporaire - Google Patents

Dispositif de fermeture pour récipients de médicaments et similaires, incluant un réceptacle temporaire Download PDF

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Publication number
EP2154081A1
EP2154081A1 EP08425543A EP08425543A EP2154081A1 EP 2154081 A1 EP2154081 A1 EP 2154081A1 EP 08425543 A EP08425543 A EP 08425543A EP 08425543 A EP08425543 A EP 08425543A EP 2154081 A1 EP2154081 A1 EP 2154081A1
Authority
EP
European Patent Office
Prior art keywords
layer
substance
closing device
container
temporary receptacle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08425543A
Other languages
German (de)
English (en)
Inventor
Giovanni Lamoure
Gianmario Lamoure
Francesco Lamoure
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merit 90 SNC Di Francesco Lamoure & C
Original Assignee
Merit 90 SNC Di Francesco Lamoure & C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merit 90 SNC Di Francesco Lamoure & C filed Critical Merit 90 SNC Di Francesco Lamoure & C
Priority to EP08425543A priority Critical patent/EP2154081A1/fr
Publication of EP2154081A1 publication Critical patent/EP2154081A1/fr
Withdrawn legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/24—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes
    • B65D51/28—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials
    • B65D51/2807—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container
    • B65D51/2814—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container the additional article or materials being released by piercing, cutting or tearing an element enclosing it
    • B65D51/2842—Closures not otherwise provided for combined or co-operating with auxiliary devices for non-closing purposes with auxiliary containers for additional articles or materials the closure presenting means for placing the additional articles or materials in contact with the main contents by acting on a part of the closure without removing the closure, e.g. by pushing down, pulling up, rotating or turning a part of the closure, or upon initial opening of the container the additional article or materials being released by piercing, cutting or tearing an element enclosing it said element being provided with a preformed weakened line

Definitions

  • the present invention relates to a closing device for containers for medicines and the like, including a temporary receptacle of the type specified in the preamble of claim 1.
  • some pharmaceuticals or medicines comprise a liquid component, disposed inside the container of the bottle, and a solid component, disposed inside the temporary receptacle part of the closing system.
  • the temporary receptacle is opened and the two substances are mixed.
  • the cutter preferably acts by means of the reciprocal movement between the container of the bottle and the closing device, during the opening and closing operations.
  • the closing device comprises a grippable outer cap that must be screwed in the direction towards the bottle to allow interaction of the cutter, integral with this cap, with the lower wall of the temporary receptacle, integral with the container.
  • Various closing devices are also present, which can, for example, present a cutter separate from the cap of the bottle and which, after these are moved towards each other, interact with the lower wall of the temporary receptacle.
  • a plunger can be present, connected to the cutter, which must be moved manually or yet other solutions can be provided.
  • the temporary container is generally made of polymer material, and in particular polyethylene, to allow easy manual cutting thereof and low production costs.
  • Said materials do not achieve perfect fluid tightness of the temporary container. Moreover, they must be of limited thickness to make cutting possible, in particular the rupture points must be thin.
  • the liquid component disposed inside the bottle evaporates and enters or migrates towards the solid powder component disposed inside the temporary receptacle.
  • the phenomenon described causes rapid deterioration of the component disposed in the temporary receptacle and therefore of the pharmaceutical or medicine in general.
  • the technical aim underlying the present invention is to create a closing device for medicine bottles and the like, including a temporary receptacle capable of substantially overcoming the aforesaid drawbacks.
  • an important object of the invention is to realize a closing device that obstructs the passage, by evaporation, of the substance contained inside the bottle into the temporary receptacle.
  • Another important object of the invention is to create a closing device that allows easy cutting of the temporary receptacle wall.
  • a further object of the invention is to obtain a simple and inexpensive closing device.
  • the closing device according to the invention is indicated as a whole with the number 1 .
  • the container 20 including a closing device 1, defines a bottle 30, generally suitable to contain medicines, pharmaceuticals and the like.
  • This container 20 comprises an opening 21 and defines an inner volume 22 suitable to contain a first substance in particular realized by a liquid substance.
  • a cylindrical receptacle made of polymeric material, more preferably polyethylene, even more preferably polyethylene terephthalate. It also comprises a containment portion 23 and a threaded portion 24 located in proximity of the opening 11 and suitable to allow joining with the closing device 1.
  • the device 1 comprises, summarily, a temporary receptacle 2 , suitable to contain a second substance, preferably a solid powder substance, a cap 3 , suitable to removably close the opening 21, and cutting means 4 , suitable to allow opening of said temporary receptacle and mixing of the first and second substance.
  • a temporary receptacle 2 suitable to contain a second substance, preferably a solid powder substance
  • a cap 3 suitable to removably close the opening 21, and cutting means 4 , suitable to allow opening of said temporary receptacle and mixing of the first and second substance.
  • the device 1 is positioned in the operating position ( Figs. 2a and 2b ) when disposed on a container 10.
  • an operating position for preservation in which the two substances remain separate
  • an operating position for use Fig. 2b
  • the two substances are reciprocally mixed
  • the temporary receptacle 2 is appropriately realized by a cylindrical body 5 comprising a lower base 6 , suitable to define the lower closure of the temporary container 2 and preferably disposed obliquely to the wall of the cylindrical body, an upper inlet 7 , defined by an opening on the upper side, and an upper flange 8 , surrounding the upper inlet 7.
  • polymeric material more preferably polyethylene, and even more preferably high density polyethylene.
  • the temporary receptacle 2 is disposed at the opening 11 of the container 10 so that the upper flange 7 abuts against the outer edge defining this opening 11, as shown in Fig. 2a .
  • the outer side of the temporary receptacle 2, in the operating position, is therefore in fluid communication with the inner volume 22 of the container 20 and preferably inserted therein.
  • a separation wall 9 is defined, part of the temporary receptacle 2 whose outer side is disposed, in the operating position for preservation, contiguous to and in fluid communication with the inner volume 22 of the container 20.
  • the inner side of the separation wall 9 is therefore in contact with the second substance. Therefore, this separation wall 9 is suitable to separate the first and the second substance.
  • the separation wall 9 is realized by a first layer 9a and a second layer 9b reciprocally superimposed, as shown in Fig. 3 .
  • the first layer 9a defines said inner side and is made of polymeric material, appropriately of the same polymer as the rest of the temporary receptacle 2. Moreover, it preferably has a thickness between 10 ⁇ m and 50 ⁇ m and more preferably between 22 ⁇ m and 28 ⁇ m.
  • the first layer 9a is preferably continuous and in one piece with the remaining part of the temporary receptacle 2.
  • the second layer 9b defines the outer side and is made of materials with a high degree of fluid tightness.
  • the second layer 9b is made of aluminium alloy, more particular in ABC aluminium. Moreover, it has a thickness preferably between 10 ⁇ m and 60 ⁇ m and more preferably between 27 ⁇ m and 33 ⁇ m.
  • the second layer 9b is made of polymeric material, in particular resin or is realized by a special paint or glue or by a special additive that modifies an outer portion of the first layer 9a.
  • this second layer 9b in particular if realized by a metallic layer, is appropriately welded for the entire contact surface to the first layer 9a, preferably heat-sealed or, alternatively, glued.
  • this second layer is also preferably realized by means of superimposing a discoidal metallic foil on the first layer 9a, so that this can adhere both to the lower base 6 and to part of the cylindrical body 5, and can cover the entire surface of the separation wall 9.
  • the second layer is realized by a resin or a glue or paint the properties of this second layer 9b allow adhesion thereof to the first layer 9a.
  • the cap 3 is suitable to removably close the opening 21 of the container 20 preferably by means of a thread 10 , connectable to the threaded portion 24 of the container 20.
  • the temporary receptacle 2 is preferably suitable to close the upper inlet 7 of the temporary receptacle 2.
  • it comprises a cylindrical portion 11 counter-shaped to the cylindrical body 5, which can be disposed inside this body and including a projection 12 suitable to guarantee fluid tightness.
  • the cylindrical portion 11 also preferably comprises the cutting means 4, realized by the lower edge thereof, as shown in Fig. 2b .
  • a spacer 13 realized by an annular element in polymer material easily releasable from the remaining portion of the cap 3.
  • the bottle 30 comprises a container 20, filled with a first substance, preferably liquid, while the temporary receptacle 2 is filled with a second substance, preferably powder.
  • the closing device 1 During storage the closing device 1 is disposed in the operating position for preservation ( Fig. 2a ). Therefore, the spacer 13 maintains the cutting means 4 at a distance from the separation wall 9 and the container 20 and receptacle 2 remain closed, reciprocally separating the substances contained.
  • the closing device 1 In a second condition of use the closing device 1 is disposed in the operating position for use ( Fig. 2b ).
  • the spacer 13 is removed from the cap 3.
  • the latter is screwed in the opposite direction to the direction of opening, pressing the cutting means 4 against the separation wall 9 and partially cutting it.
  • the temporary receptacle 2 is thus opened and the two substances are mixed.
  • the invention achieves important advantages.
  • the particular physical configuration of the separation wall 9 achieves an extremely high degree of fluid tightness thereof, without obstructing cutting operations.
  • the separation wall 9 is easily cuttable even manually.
  • the closing device 1 is inexpensive; in fact, its production cost is substantially identical to the cost of known devices including a separation wall 9 made exclusively of polymer material.
  • first layer 9a and the second layer 9b are reciprocally welded. Consequently, these walls behave as a single layer and prevent any risk of detachment of the second layer 9b.
  • the invention is susceptible to variants falling within the inventive concept.
  • the cutting means 4, the cap 3 and the temporary receptacle 2 can be of any type and shape and comprise a specific cutting plunger which can be pressed manually or a cutter separate from the cap and also external to the closing device 1.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
EP08425543A 2008-08-06 2008-08-06 Dispositif de fermeture pour récipients de médicaments et similaires, incluant un réceptacle temporaire Withdrawn EP2154081A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP08425543A EP2154081A1 (fr) 2008-08-06 2008-08-06 Dispositif de fermeture pour récipients de médicaments et similaires, incluant un réceptacle temporaire

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP08425543A EP2154081A1 (fr) 2008-08-06 2008-08-06 Dispositif de fermeture pour récipients de médicaments et similaires, incluant un réceptacle temporaire

Publications (1)

Publication Number Publication Date
EP2154081A1 true EP2154081A1 (fr) 2010-02-17

Family

ID=40019267

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08425543A Withdrawn EP2154081A1 (fr) 2008-08-06 2008-08-06 Dispositif de fermeture pour récipients de médicaments et similaires, incluant un réceptacle temporaire

Country Status (1)

Country Link
EP (1) EP2154081A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20111453A1 (it) * 2011-07-29 2013-01-30 S M P S R L Dispositivo con serbatoio di contenimento di una prima sostanza per la chiusura di un flacone di contenimento di una seconda sostanza da mantenere separata dalla prima sostanza fino al momento della miscelazione con essa
IT201900005112A1 (it) * 2019-04-04 2020-10-04 Sacmi Capsula di chiusura per un contenitore
GB2595478A (en) * 2020-05-27 2021-12-01 Medcap Ltd Dispenser for selectively delivering a substance in a container
US12122575B2 (en) 2019-04-04 2024-10-22 Sacmi Cooperativa Meccanici Imola Societa' Cooperativa Closing cap for a container

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0093090A2 (fr) * 1982-04-23 1983-11-02 CAPSULIT S.r.l. Fermeture pour bouteilles comprenant un récipient cassable
IT1307797B1 (it) 1999-09-28 2001-11-19 Freeplast S R L Una capsula per la chiusura di un contenitore e una confezionecomprendente un contenitore e detta capsula per il confezionamento
WO2007010560A1 (fr) * 2005-07-15 2007-01-25 Bormioli Rocco & Figlio S.P.A. Réservoir doté d’un dispositif de coupe destiné à des substances se melangeant à des liquides au moment de l’utilisation, réservoir destiné en particulier à des récipients à dose unique

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0093090A2 (fr) * 1982-04-23 1983-11-02 CAPSULIT S.r.l. Fermeture pour bouteilles comprenant un récipient cassable
IT1307797B1 (it) 1999-09-28 2001-11-19 Freeplast S R L Una capsula per la chiusura di un contenitore e una confezionecomprendente un contenitore e detta capsula per il confezionamento
WO2007010560A1 (fr) * 2005-07-15 2007-01-25 Bormioli Rocco & Figlio S.P.A. Réservoir doté d’un dispositif de coupe destiné à des substances se melangeant à des liquides au moment de l’utilisation, réservoir destiné en particulier à des récipients à dose unique

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20111453A1 (it) * 2011-07-29 2013-01-30 S M P S R L Dispositivo con serbatoio di contenimento di una prima sostanza per la chiusura di un flacone di contenimento di una seconda sostanza da mantenere separata dalla prima sostanza fino al momento della miscelazione con essa
WO2013018009A1 (fr) * 2011-07-29 2013-02-07 S.M.P. S.R.L. Dispositif doté d'un réservoir de confinement d'une première substance permettant de fermer une bouteille de confinement d'une seconde substance devant être conservée séparément de la première substance jusqu'au moment du mélange avec celle-ci
IT201900005112A1 (it) * 2019-04-04 2020-10-04 Sacmi Capsula di chiusura per un contenitore
WO2020201980A1 (fr) * 2019-04-04 2020-10-08 Sacmi Cooperativa Meccanici Imola Societa' Cooperativa Capuchon de fermeture pour un récipient
CN113853342A (zh) * 2019-04-04 2021-12-28 萨克米伊莫拉机械合作社合作公司 用于容器的封闭盖
CN113853342B (zh) * 2019-04-04 2023-05-26 萨克米伊莫拉机械合作社合作公司 用于容器的封闭盖
US12122575B2 (en) 2019-04-04 2024-10-22 Sacmi Cooperativa Meccanici Imola Societa' Cooperativa Closing cap for a container
GB2595478A (en) * 2020-05-27 2021-12-01 Medcap Ltd Dispenser for selectively delivering a substance in a container
WO2021239853A1 (fr) * 2020-05-27 2021-12-02 Medcap Limited Distributeur pour distribuer sélectivement une substance dans un récipient

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