EP2148708A4 - Composition favorisant la formation osseuse - Google Patents

Composition favorisant la formation osseuse

Info

Publication number
EP2148708A4
EP2148708A4 EP08748149A EP08748149A EP2148708A4 EP 2148708 A4 EP2148708 A4 EP 2148708A4 EP 08748149 A EP08748149 A EP 08748149A EP 08748149 A EP08748149 A EP 08748149A EP 2148708 A4 EP2148708 A4 EP 2148708A4
Authority
EP
European Patent Office
Prior art keywords
composition
bone formation
enhancing bone
enhancing
formation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08748149A
Other languages
German (de)
English (en)
Other versions
EP2148708A1 (fr
Inventor
Jake Barralet
Nihouannen Damien Le
Svetlana Komarova
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
McGill University
Original Assignee
McGill University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by McGill University filed Critical McGill University
Publication of EP2148708A1 publication Critical patent/EP2148708A1/fr
Publication of EP2148708A4 publication Critical patent/EP2148708A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/191Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/12Phosphorus-containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412Tissue-regenerating or healing or proliferative agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/426Immunomodulating agents, i.e. cytokines, interleukins, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/80Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
    • A61L2300/802Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/02Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Surgery (AREA)
  • Materials For Medical Uses (AREA)
EP08748149A 2007-04-18 2008-04-18 Composition favorisant la formation osseuse Withdrawn EP2148708A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90780207P 2007-04-18 2007-04-18
PCT/CA2008/000733 WO2008128342A1 (fr) 2007-04-18 2008-04-18 Composition favorisant la formation osseuse

Publications (2)

Publication Number Publication Date
EP2148708A1 EP2148708A1 (fr) 2010-02-03
EP2148708A4 true EP2148708A4 (fr) 2012-12-05

Family

ID=39875020

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08748149A Withdrawn EP2148708A4 (fr) 2007-04-18 2008-04-18 Composition favorisant la formation osseuse

Country Status (4)

Country Link
US (2) US20100303888A1 (fr)
EP (1) EP2148708A4 (fr)
CA (1) CA2720269A1 (fr)
WO (1) WO2008128342A1 (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2358352B1 (fr) * 2008-10-24 2018-08-29 Warsaw Orthopedic, Inc. Compositions et procédés pour favoriser la formation osseuse
US8709149B2 (en) 2008-11-12 2014-04-29 Ossdsign Ab Hydraulic cements, methods and products
DE102009013957B4 (de) * 2009-03-13 2011-04-07 Technische Universität Dresden Verfahren und Mittel zum Nachweis der Aktivität von Osteoklasten
RU2562596C2 (ru) 2010-03-10 2015-09-10 Осс-К Аб Имплантаты и способы коррекции дефектов ткани
TWI579007B (zh) * 2010-07-02 2017-04-21 艾格諾福斯保健公司 骨再生材料之用途
US9463046B2 (en) 2011-08-22 2016-10-11 Ossdsign Ab Implants and methods for using such implants to fill holes in bone tissue
US20130066327A1 (en) 2011-09-09 2013-03-14 Håkan Engqvist Hydraulic cement compositions with low ph methods, articles and kits
US8591645B2 (en) 2011-09-09 2013-11-26 Ossdsign Ab Hydraulic cements with optimized grain size distribution, methods, articles and kits
US20140052264A1 (en) * 2012-08-20 2014-02-20 Ticona Llc Porous, Stabilized Craniomaxillofacial Implants and Methods and Kits Relating Thereto
UA110269C2 (uk) * 2012-12-03 2015-12-10 Saint Gobain Placo Хімічна добавка для гіпсових виробів
US9913931B2 (en) 2012-12-14 2018-03-13 Ossdsign Ab Cement-forming compositions, monetite cements, implants and methods for correcting bone defects
EA201591152A1 (ru) * 2013-02-11 2016-03-31 Аморфикал Лтд. Аморфный карбонат кальция для ускоренного роста костной ткани
EP2956088A2 (fr) 2013-02-12 2015-12-23 OssDsign AB Implants en mosaïques, kits et procédés de correction de défauts osseux
KR20170043110A (ko) 2014-08-14 2017-04-20 오에스에스디자인 아베 뼈 결함 교정을 위한 뼈 이식
US10632227B2 (en) 2015-02-09 2020-04-28 Wayne State University Method of making injectable cements
CN115737932B (zh) * 2022-11-23 2024-04-26 国纳之星(上海)纳米科技发展有限公司 负载x射线诱导光动力治疗/放疗协同诊疗一体化探针的骨水泥的制备及产品和应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004093995A2 (fr) * 2003-04-17 2004-11-04 St George's Enterprises Limited Utilisation d'antioxydants pour traiter les troubles associes a la perte osseuse
US20050197397A1 (en) * 2001-09-11 2005-09-08 Alain Martin Method and composition for treating mammalian diseases and injuries caused by the over-expression of peroxynitrite
US20060074225A1 (en) * 2004-09-14 2006-04-06 Xencor, Inc. Monomeric immunoglobulin Fc domains

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9204303A (es) * 1991-07-23 1993-11-01 Rhone Poulenc Rorer Int Factor regulador del crecimiento de osteoclasto.
ATE296643T1 (de) * 1999-02-04 2005-06-15 Sdgi Holdings Inc Osteogene pastenzusammensetzungen und ihre verwendung
DE60006356T2 (de) * 1999-02-04 2004-09-09 SDGI Holding, Inc., Wilmington Hochmineralisierte osteogene schwammzusammensetzungen und ihre verwendung
WO2003026689A1 (fr) * 2001-09-24 2003-04-03 Verigen Ag Composition cocktail a base de facteurs de croissance autologues, son procede de production et son utilisation
US20040002770A1 (en) * 2002-06-28 2004-01-01 King Richard S. Polymer-bioceramic composite for orthopaedic applications and method of manufacture thereof
SE0300620D0 (sv) * 2003-03-05 2003-03-05 Bone Support Ab A new bone substitute composition
US7252833B2 (en) * 2003-11-18 2007-08-07 Skeletal Kinetics, Llc Calcium phosphate cements comprising an osteoclastogenic agent

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050197397A1 (en) * 2001-09-11 2005-09-08 Alain Martin Method and composition for treating mammalian diseases and injuries caused by the over-expression of peroxynitrite
WO2004093995A2 (fr) * 2003-04-17 2004-11-04 St George's Enterprises Limited Utilisation d'antioxydants pour traiter les troubles associes a la perte osseuse
US20060074225A1 (en) * 2004-09-14 2006-04-06 Xencor, Inc. Monomeric immunoglobulin Fc domains

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
See also references of WO2008128342A1 *
XIA Z ET AL: "In vitro biodegradation of three brushite calcium phosphate cements by a macrophage cell-line", BIOMATERIALS, ELSEVIER SCIENCE PUBLISHERS BV., BARKING, GB, vol. 27, no. 26, 1 September 2006 (2006-09-01), pages 4557 - 4565, XP027951254, ISSN: 0142-9612, [retrieved on 20060901] *

Also Published As

Publication number Publication date
CA2720269A1 (fr) 2008-10-30
WO2008128342A1 (fr) 2008-10-30
US20130121956A1 (en) 2013-05-16
WO2008128342A9 (fr) 2009-04-30
EP2148708A1 (fr) 2010-02-03
US20100303888A1 (en) 2010-12-02

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Legal Events

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Effective date: 20121105

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 47/26 20060101ALI20121029BHEP

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