EP2121715A4 - BLOCKING OF THE MIGRATION OR METASTASE OF CANCER CELLS THROUGH THE MOUNTING OF HARD PROTEINS AND APPLICATIONS OF THE NEW COMPOUNDS OBTAINED THEREFROM - Google Patents

BLOCKING OF THE MIGRATION OR METASTASE OF CANCER CELLS THROUGH THE MOUNTING OF HARD PROTEINS AND APPLICATIONS OF THE NEW COMPOUNDS OBTAINED THEREFROM

Info

Publication number
EP2121715A4
EP2121715A4 EP08725693A EP08725693A EP2121715A4 EP 2121715 A4 EP2121715 A4 EP 2121715A4 EP 08725693 A EP08725693 A EP 08725693A EP 08725693 A EP08725693 A EP 08725693A EP 2121715 A4 EP2121715 A4 EP 2121715A4
Authority
EP
European Patent Office
Prior art keywords
metastasis
migration
blocking
cancer cells
new compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP08725693A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP2121715A1 (en
Inventor
Pui-Kwong Chan
May Sung Mak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pacific Arrow Ltd
Original Assignee
Pacific Arrow Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/683,198 external-priority patent/US8614197B2/en
Priority claimed from PCT/US2007/077273 external-priority patent/WO2008028060A2/en
Application filed by Pacific Arrow Ltd filed Critical Pacific Arrow Ltd
Publication of EP2121715A1 publication Critical patent/EP2121715A1/en
Publication of EP2121715A4 publication Critical patent/EP2121715A4/en
Withdrawn legal-status Critical Current

Links

Classifications

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/04—Nitro compounds
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A—HUMAN NECESSITIES
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    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • A—HUMAN NECESSITIES
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    • A61P5/00—Drugs for disorders of the endocrine system
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/256—Polyterpene radicals

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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Neurology (AREA)
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  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Vascular Medicine (AREA)
  • Reproductive Health (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Pregnancy & Childbirth (AREA)
EP08725693A 2007-02-16 2008-02-15 BLOCKING OF THE MIGRATION OR METASTASE OF CANCER CELLS THROUGH THE MOUNTING OF HARD PROTEINS AND APPLICATIONS OF THE NEW COMPOUNDS OBTAINED THEREFROM Withdrawn EP2121715A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US89038007P 2007-02-16 2007-02-16
US11/683,198 US8614197B2 (en) 2003-10-09 2007-03-07 Anti-tumor compounds with angeloyl groups
US94770507P 2007-07-03 2007-07-03
PCT/US2007/077273 WO2008028060A2 (en) 2006-09-01 2007-08-30 Anti-tumor compounds for inhibiting cancer growth
PCT/US2008/002086 WO2008133766A1 (en) 2007-02-16 2008-02-15 Blocking the migration or metastasis of cancer cells by affecting adhesion proteins and the uses of new compounds thereof

Publications (2)

Publication Number Publication Date
EP2121715A1 EP2121715A1 (en) 2009-11-25
EP2121715A4 true EP2121715A4 (en) 2010-12-29

Family

ID=39925959

Family Applications (1)

Application Number Title Priority Date Filing Date
EP08725693A Withdrawn EP2121715A4 (en) 2007-02-16 2008-02-15 BLOCKING OF THE MIGRATION OR METASTASE OF CANCER CELLS THROUGH THE MOUNTING OF HARD PROTEINS AND APPLICATIONS OF THE NEW COMPOUNDS OBTAINED THEREFROM

Country Status (7)

Country Link
EP (1) EP2121715A4 (ja)
JP (1) JP2010519219A (ja)
CN (1) CN101772511A (ja)
AU (1) AU2008244648A1 (ja)
CA (1) CA2676791A1 (ja)
SG (1) SG178795A1 (ja)
WO (1) WO2008133766A1 (ja)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7524824B2 (en) 2003-09-04 2009-04-28 Pacific Arrow Limited Composition comprising Xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof
US7727561B2 (en) 2001-08-31 2010-06-01 Pacific Arrow Limited Composition comprising Xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof
US8614197B2 (en) 2003-10-09 2013-12-24 Pacific Arrow Limited Anti-tumor compounds with angeloyl groups
US7514412B2 (en) 2003-10-09 2009-04-07 Pacific Arrow Limited Anticancer biangeloyl saponins
US7488753B2 (en) 2003-10-09 2009-02-10 Pacific Arrow Limited Composition comprising triterpene saponins and compounds with angeloyl functional group, methods for preparing same and uses thereof
US8586719B2 (en) 2005-04-27 2013-11-19 Pacific Arrow Limited Triterpenes for modulating gene expression and cell membrane, and as antiprotozoal agents
US20120277308A1 (en) 2010-07-16 2012-11-01 Pacific Arrow Limited compounds for treating cancer and other diseases
CN106905403B (zh) * 2010-07-16 2020-10-23 太平洋艾瑞有限公司 可治疗癌症和其它疾病的新化合物
KR101398079B1 (ko) * 2011-10-10 2014-05-27 재단법인 의약바이오컨버젼스연구단 글리실-티알엔에이 합성효소 및 캐드헤린을 이용한 암 예방 또는 치료제의 스크리닝 방법
KR101403019B1 (ko) 2013-02-25 2014-06-03 서울대학교산학협력단 폐암 진단용 마커
KR20150122786A (ko) * 2013-03-15 2015-11-02 펀다시오 인스티튜트 드 르세르카 바이오메디카 (아이알비 바르셀로나) 암 전이의 진단, 예후 및 치료를 위한 방법
CN103235141A (zh) * 2013-04-27 2013-08-07 上海交通大学医学院附属新华医院 Atf3用于预测膀胱癌转移和判断预后的应用
JP6339814B2 (ja) * 2014-02-05 2018-06-06 株式会社島津製作所 がん転移マーカー及びその分析方法
CN104502603B (zh) * 2014-12-03 2016-04-06 上海交通大学医学院附属上海儿童医学中心 Myo1d作为诊断动脉导管闭合或开放的标志物
KR20170093182A (ko) 2014-12-11 2017-08-14 인바이오모션 에스.엘. 인간 c-maf에 대한 결합 구성원
CN105061545B (zh) * 2015-08-17 2018-01-30 中国人民解放军第二一〇医院 文冠果中三萜皂苷类化合物及其制备方法和应用
US10167293B2 (en) * 2016-05-26 2019-01-01 Bayer Pharma Aktiengesellschaft [8-(phenylsulfonyl)-3,8-diazabicyclo[3.2.1]oct-3-yl](1H-1,2,3-triazol-4-yl)methanones
CN106947821B (zh) * 2017-04-11 2020-06-30 成都望路医药技术有限公司 用于诊治结肠腺癌的生物标志物
CN108410986B (zh) * 2018-02-26 2021-06-22 中国人民解放军总医院 Cdh6促进骨肉瘤生长和转移
CN110272997B (zh) * 2018-03-14 2023-04-28 华中科技大学同济医学院附属同济医院 一种C/EBPβ基因或者蛋白的用途
KR102128331B1 (ko) * 2018-04-30 2020-06-30 인하대학교 산학협력단 Cdh13 또는 이를 코딩하는 유전자의 발현을 억제하는 제제를 포함하는, 방사선 치료로 인하여 노화된 혈관내피세포로 전이가 발생하는 암 전이 억제용 조성물
CN109970839B (zh) * 2019-04-16 2022-03-01 沈阳药科大学 三萜皂苷类化合物及其制备方法和医药用途
CN110672848A (zh) * 2019-10-25 2020-01-10 四川大学华西医院 Apeh自身抗体检测试剂在制备肺癌筛查试剂盒中的用途

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005037200A2 (en) * 2003-10-09 2005-04-28 Pacific Arrow Limited Composition comprising xanthoceras sorbifolia extracts, compounds isolated from same, methods for preparing same and uses thereof
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CN101772511A (zh) 2010-07-07
JP2010519219A (ja) 2010-06-03
WO2008133766A1 (en) 2008-11-06

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