EP2115465A4 - Applications chirurgicales pour une proteine de liaison a bmp - Google Patents

Applications chirurgicales pour une proteine de liaison a bmp

Info

Publication number
EP2115465A4
EP2115465A4 EP07868028A EP07868028A EP2115465A4 EP 2115465 A4 EP2115465 A4 EP 2115465A4 EP 07868028 A EP07868028 A EP 07868028A EP 07868028 A EP07868028 A EP 07868028A EP 2115465 A4 EP2115465 A4 EP 2115465A4
Authority
EP
European Patent Office
Prior art keywords
binding protein
surgical applications
bmp binding
bmp
surgical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP07868028A
Other languages
German (de)
English (en)
Other versions
EP2115465A2 (fr
Inventor
Samuel S Murray
Elsa J Murray
Keyvan Behnam
Jeffrey C Wang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
US Department of Veterans Affairs VA
Original Assignee
University of California
US Department of Veterans Affairs VA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/985,745 external-priority patent/US8193312B2/en
Application filed by University of California, US Department of Veterans Affairs VA filed Critical University of California
Publication of EP2115465A2 publication Critical patent/EP2115465A2/fr
Publication of EP2115465A4 publication Critical patent/EP2115465A4/fr
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1841—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
EP07868028A 2006-12-22 2007-12-26 Applications chirurgicales pour une proteine de liaison a bmp Ceased EP2115465A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87682106P 2006-12-22 2006-12-22
US11/985,745 US8193312B2 (en) 2004-01-28 2007-11-16 Bone morphogenic protein binding peptide
PCT/US2007/026315 WO2008079400A2 (fr) 2006-12-22 2007-12-26 Applications chirurgicales pour une protéine de liaison à bmp

Publications (2)

Publication Number Publication Date
EP2115465A2 EP2115465A2 (fr) 2009-11-11
EP2115465A4 true EP2115465A4 (fr) 2011-08-10

Family

ID=39563120

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07868028A Ceased EP2115465A4 (fr) 2006-12-22 2007-12-26 Applications chirurgicales pour une proteine de liaison a bmp

Country Status (5)

Country Link
EP (1) EP2115465A4 (fr)
JP (1) JP5466017B2 (fr)
AU (1) AU2007338627B2 (fr)
CA (1) CA2673600A1 (fr)
WO (1) WO2008079400A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8193312B2 (en) * 2004-01-28 2012-06-05 The Regents Of The University Of California Bone morphogenic protein binding peptide
WO2005072403A2 (fr) 2004-01-28 2005-08-11 The Regents Of The University Of California Peptide fixant la proteine morphogenetique osseuse
US8415302B2 (en) 2004-01-28 2013-04-09 The Regents Of The University Of California Surgical applications for BMP binding protein
US8753660B2 (en) 2004-11-29 2014-06-17 The Regents Of The University Of California Activating extraction of demineralized bone matrix
US9072709B2 (en) 2009-06-23 2015-07-07 The Regents Of The University Of California Enhancement of bone morphogenic protein (BMP) retention with BMP binding peptide (BBP)
JP2018525446A (ja) * 2015-08-25 2018-09-06 ヒスタイド アクツィエンゲゼルシャフト 組織形成誘導用化合物及びその使用
US20190225651A1 (en) * 2015-08-25 2019-07-25 Histide Ag Compounds for inducing tissue formation and uses thereof
US20210162023A1 (en) * 2018-08-10 2021-06-03 Alexion Pharmaceuticals, Inc. Methods of treating neurofibromatosis type 1 and related conditions with alkaline phosphatase
CN117836317A (zh) * 2021-07-05 2024-04-05 马斯特里赫特大学 治疗钙晶体沉积疾病的手段和方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0409472A1 (fr) * 1989-07-19 1991-01-23 Chiron Corporation Protéine morphogénétique d'origine osseuse
WO2005072403A2 (fr) * 2004-01-28 2005-08-11 The Regents Of The University Of California Peptide fixant la proteine morphogenetique osseuse
WO2006093545A1 (fr) * 2004-11-29 2006-09-08 The Regents Of The University Of California Activation de l'extraction de la matrice osseuse demineralisee

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0409472A1 (fr) * 1989-07-19 1991-01-23 Chiron Corporation Protéine morphogénétique d'origine osseuse
WO2005072403A2 (fr) * 2004-01-28 2005-08-11 The Regents Of The University Of California Peptide fixant la proteine morphogenetique osseuse
WO2006093545A1 (fr) * 2004-11-29 2006-09-08 The Regents Of The University Of California Activation de l'extraction de la matrice osseuse demineralisee

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BEHNAM K ET AL: "BMP binding peptide: a BMP-2 enhancing factor deduced from the sequence of native bovine bone morphogenetic protein/non-collagenous protein", JOURNAL OF ORTHOPAEDIC RESEARCH, JOHN WILEY & SONS, INC, NEEDHAM, MA, vol. 23, no. 1, 1 January 2005 (2005-01-01), pages 175 - 180, XP004686456, ISSN: 0736-0266, DOI: 10.1016/J.ORTHRES.2004.05.001 *
HU B ET AL: "ISOLATION AND MOLECULAR CLONING OF A NOVEL BONE PHOSPHOPROTEIN RELATED IN SEQUENCE TO THE CYSTATIN FAMILY OF THIOL PROTEASE INHIBITORS", JOURNAL OF BIOLOGICAL CHEMISTRY, THE AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, INC., BALTIMORE, MD, US, vol. 270, no. 1, 1 January 1995 (1995-01-01), pages 431 - 436, XP000872932, ISSN: 0021-9258, DOI: 10.1074/JBC.270.1.431 *

Also Published As

Publication number Publication date
CA2673600A1 (fr) 2008-07-03
WO2008079400A3 (fr) 2008-08-21
EP2115465A2 (fr) 2009-11-11
AU2007338627A2 (en) 2010-01-28
AU2007338627A1 (en) 2008-07-03
AU2007338627B2 (en) 2013-08-15
JP5466017B2 (ja) 2014-04-09
WO2008079400A2 (fr) 2008-07-03
JP2010513535A (ja) 2010-04-30

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

RIN1 Information on inventor provided before grant (corrected)

Inventor name: WANG, JEFFREY C.

Inventor name: BEHNAM, KEYVAN

Inventor name: MURRAY, SAMUEL S.

Inventor name: MURRAY, ELSA J.

DAX Request for extension of the european patent (deleted)
A4 Supplementary search report drawn up and despatched

Effective date: 20110712

RIC1 Information provided on ipc code assigned before grant

Ipc: A61K 38/18 20060101AFI20110706BHEP

Ipc: C07K 14/51 20060101ALI20110706BHEP

Ipc: A61P 19/00 20060101ALI20110706BHEP

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