EP2114305A4 - Valve prosthesis systems and methods - Google Patents

Valve prosthesis systems and methods

Info

Publication number
EP2114305A4
EP2114305A4 EP08713452.4A EP08713452A EP2114305A4 EP 2114305 A4 EP2114305 A4 EP 2114305A4 EP 08713452 A EP08713452 A EP 08713452A EP 2114305 A4 EP2114305 A4 EP 2114305A4
Authority
EP
European Patent Office
Prior art keywords
methods
valve prosthesis
prosthesis systems
systems
valve
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP08713452.4A
Other languages
German (de)
French (fr)
Other versions
EP2114305B1 (en
EP2114305A2 (en
Inventor
David G Lamphere
Tuan Anh Nguyen
Howard C Herrmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pennsylvania Penn
EndoValve Inc
Original Assignee
University of Pennsylvania Penn
EndoValve Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Pennsylvania Penn, EndoValve Inc filed Critical University of Pennsylvania Penn
Publication of EP2114305A2 publication Critical patent/EP2114305A2/en
Publication of EP2114305A4 publication Critical patent/EP2114305A4/en
Application granted granted Critical
Publication of EP2114305B1 publication Critical patent/EP2114305B1/en
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2427—Devices for manipulating or deploying heart valves during implantation
    • A61F2/2436—Deployment by retracting a sheath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2427—Devices for manipulating or deploying heart valves during implantation
    • A61F2/2439—Expansion controlled by filaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2427—Devices for manipulating or deploying heart valves during implantation
    • A61F2/243—Deployment by mechanical expansion

Landscapes

  • Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)
  • Surgical Instruments (AREA)
EP08713452.4A 2007-02-23 2008-01-03 Valve prosthesis systems and methods Not-in-force EP2114305B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US90298807P 2007-02-23 2007-02-23
US11/869,972 US7753949B2 (en) 2007-02-23 2007-10-10 Valve prosthesis systems and methods
PCT/US2008/050096 WO2008103497A2 (en) 2007-02-23 2008-01-03 Valve prosthesis systems and methods

Publications (3)

Publication Number Publication Date
EP2114305A2 EP2114305A2 (en) 2009-11-11
EP2114305A4 true EP2114305A4 (en) 2013-05-15
EP2114305B1 EP2114305B1 (en) 2018-09-05

Family

ID=39710690

Family Applications (2)

Application Number Title Priority Date Filing Date
EP08713452.4A Not-in-force EP2114305B1 (en) 2007-02-23 2008-01-03 Valve prosthesis systems and methods
EP08713462A Withdrawn EP2114306A2 (en) 2007-02-23 2008-01-03 Systems and methods for placement of valve phosthesis system

Family Applications After (1)

Application Number Title Priority Date Filing Date
EP08713462A Withdrawn EP2114306A2 (en) 2007-02-23 2008-01-03 Systems and methods for placement of valve phosthesis system

Country Status (7)

Country Link
US (2) US7753949B2 (en)
EP (2) EP2114305B1 (en)
JP (2) JP2010518976A (en)
AU (2) AU2008218948A1 (en)
CA (2) CA2678971A1 (en)
IL (2) IL200430A0 (en)
WO (2) WO2008103497A2 (en)

Families Citing this family (331)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1447669A (en) 2000-08-18 2003-10-08 阿特里泰克公司 Expandable implant devices for filtering blood flow from atrial appendages
US6893459B1 (en) * 2000-09-20 2005-05-17 Ample Medical, Inc. Heart valve annulus device and method of using same
WO2004030568A2 (en) * 2002-10-01 2004-04-15 Ample Medical, Inc. Device and method for repairing a native heart valve leaflet
US7621948B2 (en) * 2003-07-21 2009-11-24 The Trustees Of The University Of Pennsylvania Percutaneous heart valve
US8840663B2 (en) 2003-12-23 2014-09-23 Sadra Medical, Inc. Repositionable heart valve method
US8343213B2 (en) 2003-12-23 2013-01-01 Sadra Medical, Inc. Leaflet engagement elements and methods for use thereof
US8951299B2 (en) 2003-12-23 2015-02-10 Sadra Medical, Inc. Medical devices and delivery systems for delivering medical devices
US20120041550A1 (en) 2003-12-23 2012-02-16 Sadra Medical, Inc. Methods and Apparatus for Endovascular Heart Valve Replacement Comprising Tissue Grasping Elements
US7959666B2 (en) 2003-12-23 2011-06-14 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a heart valve
US9005273B2 (en) 2003-12-23 2015-04-14 Sadra Medical, Inc. Assessing the location and performance of replacement heart valves
US7780725B2 (en) 2004-06-16 2010-08-24 Sadra Medical, Inc. Everting heart valve
US8579962B2 (en) 2003-12-23 2013-11-12 Sadra Medical, Inc. Methods and apparatus for performing valvuloplasty
US9526609B2 (en) 2003-12-23 2016-12-27 Boston Scientific Scimed, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8603160B2 (en) 2003-12-23 2013-12-10 Sadra Medical, Inc. Method of using a retrievable heart valve anchor with a sheath
US7381219B2 (en) 2003-12-23 2008-06-03 Sadra Medical, Inc. Low profile heart valve and delivery system
US7329279B2 (en) 2003-12-23 2008-02-12 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8182528B2 (en) 2003-12-23 2012-05-22 Sadra Medical, Inc. Locking heart valve anchor
US7445631B2 (en) 2003-12-23 2008-11-04 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US8828078B2 (en) 2003-12-23 2014-09-09 Sadra Medical, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US20050137694A1 (en) 2003-12-23 2005-06-23 Haug Ulrich R. Methods and apparatus for endovascularly replacing a patient's heart valve
EP2526899B1 (en) 2003-12-23 2014-01-29 Sadra Medical, Inc. Repositionable heart valve
US20050137687A1 (en) 2003-12-23 2005-06-23 Sadra Medical Heart valve anchor and method
US11278398B2 (en) 2003-12-23 2022-03-22 Boston Scientific Scimed, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
DE102005003632A1 (en) 2005-01-20 2006-08-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Catheter for the transvascular implantation of heart valve prostheses
US7962208B2 (en) 2005-04-25 2011-06-14 Cardiac Pacemakers, Inc. Method and apparatus for pacing during revascularization
US8852270B2 (en) 2007-11-15 2014-10-07 Cardiosolutions, Inc. Implant delivery system and method
US8092525B2 (en) 2005-10-26 2012-01-10 Cardiosolutions, Inc. Heart valve implant
US8216302B2 (en) 2005-10-26 2012-07-10 Cardiosolutions, Inc. Implant delivery and deployment system and method
US7785366B2 (en) 2005-10-26 2010-08-31 Maurer Christopher W Mitral spacer
US8449606B2 (en) 2005-10-26 2013-05-28 Cardiosolutions, Inc. Balloon mitral spacer
US9259317B2 (en) 2008-06-13 2016-02-16 Cardiosolutions, Inc. System and method for implanting a heart implant
US8778017B2 (en) 2005-10-26 2014-07-15 Cardiosolutions, Inc. Safety for mitral valve implant
AU2006315812B2 (en) 2005-11-10 2013-03-28 Cardiaq Valve Technologies, Inc. Balloon-expandable, self-expanding, vascular prosthesis connecting stent
US20070213813A1 (en) 2005-12-22 2007-09-13 Symetis Sa Stent-valves for valve replacement and associated methods and systems for surgery
CN101415379B (en) 2006-02-14 2012-06-20 萨德拉医学公司 Systems for delivering a medical implant
US20090306768A1 (en) 2006-07-28 2009-12-10 Cardiaq Valve Technologies, Inc. Percutaneous valve prosthesis and system and method for implanting same
US8070802B2 (en) * 2007-02-23 2011-12-06 The Trustees Of The University Of Pennsylvania Mitral valve system
US7753949B2 (en) * 2007-02-23 2010-07-13 The Trustees Of The University Of Pennsylvania Valve prosthesis systems and methods
US7896915B2 (en) 2007-04-13 2011-03-01 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
US8480730B2 (en) 2007-05-14 2013-07-09 Cardiosolutions, Inc. Solid construct mitral spacer
DE102007043830A1 (en) 2007-09-13 2009-04-02 Lozonschi, Lucian, Madison Heart valve stent
US8597347B2 (en) 2007-11-15 2013-12-03 Cardiosolutions, Inc. Heart regurgitation method and apparatus
US7846199B2 (en) * 2007-11-19 2010-12-07 Cook Incorporated Remodelable prosthetic valve
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
BR112012021347A2 (en) 2008-02-26 2019-09-24 Jenavalve Tecnology Inc stent for positioning and anchoring a valve prosthesis at an implantation site in a patient's heart
AU2009240565B2 (en) * 2008-04-23 2013-08-22 Medtronic, Inc. Stented heart valve devices
US8323336B2 (en) * 2008-04-23 2012-12-04 Medtronic, Inc. Prosthetic heart valve devices and methods of valve replacement
US8591460B2 (en) * 2008-06-13 2013-11-26 Cardiosolutions, Inc. Steerable catheter and dilator and system and method for implanting a heart implant
US8323335B2 (en) 2008-06-20 2012-12-04 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic valves and methods for using
US8652202B2 (en) 2008-08-22 2014-02-18 Edwards Lifesciences Corporation Prosthetic heart valve and delivery apparatus
EP2367505B1 (en) 2008-09-29 2020-08-12 Edwards Lifesciences CardiAQ LLC Heart valve
WO2010040009A1 (en) 2008-10-01 2010-04-08 Cardiaq Valve Technologies, Inc. Delivery system for vascular implant
US8690936B2 (en) 2008-10-10 2014-04-08 Edwards Lifesciences Corporation Expandable sheath for introducing an endovascular delivery device into a body
US8137398B2 (en) * 2008-10-13 2012-03-20 Medtronic Ventor Technologies Ltd Prosthetic valve having tapered tip when compressed for delivery
US9072583B2 (en) * 2008-10-16 2015-07-07 Obalon Therapeutics, Inc. Intragastric volume-occupying device and method for fabricating same
JP2012520716A (en) * 2009-03-17 2012-09-10 ミトラシスト メディカル リミテッド Artificial valve having a folding valve and its delivery method
US8052741B2 (en) * 2009-03-23 2011-11-08 Medtronic Vascular, Inc. Branch vessel prosthesis with a roll-up sealing assembly
US8414644B2 (en) 2009-04-15 2013-04-09 Cardiaq Valve Technologies, Inc. Vascular implant and delivery system
US9730790B2 (en) 2009-09-29 2017-08-15 Edwards Lifesciences Cardiaq Llc Replacement valve and method
US8449599B2 (en) * 2009-12-04 2013-05-28 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US8870950B2 (en) 2009-12-08 2014-10-28 Mitral Tech Ltd. Rotation-based anchoring of an implant
EP3649985B8 (en) 2009-12-08 2021-04-21 Avalon Medical Ltd. Device and system for transcatheter mitral valve replacement
US9522062B2 (en) 2010-02-24 2016-12-20 Medtronic Ventor Technologies, Ltd. Mitral prosthesis and methods for implantation
US9072603B2 (en) 2010-02-24 2015-07-07 Medtronic Ventor Technologies, Ltd. Mitral prosthesis and methods for implantation
HUE059497T2 (en) 2010-03-05 2022-11-28 Edwards Lifesciences Corp Retaining mechanisms for prosthetic valves
WO2011111047A2 (en) 2010-03-10 2011-09-15 Mitraltech Ltd. Prosthetic mitral valve with tissue anchors
US8579964B2 (en) 2010-05-05 2013-11-12 Neovasc Inc. Transcatheter mitral valve prosthesis
CA2799459A1 (en) 2010-05-25 2011-12-01 Jenavalve Technology Inc. Prosthetic heart valve and transcatheter delivered endoprosthesis comprising a prosthetic heart valve and a stent
CA2803149C (en) 2010-06-21 2018-08-14 Impala, Inc. Replacement heart valve
AU2011275468B2 (en) 2010-07-09 2014-02-06 Highlife Sas Transcatheter atrio-ventricular valve prosthesis
US9763657B2 (en) 2010-07-21 2017-09-19 Mitraltech Ltd. Techniques for percutaneous mitral valve replacement and sealing
US11653910B2 (en) 2010-07-21 2023-05-23 Cardiovalve Ltd. Helical anchor implantation
US9132009B2 (en) 2010-07-21 2015-09-15 Mitraltech Ltd. Guide wires with commissural anchors to advance a prosthetic valve
US8992604B2 (en) 2010-07-21 2015-03-31 Mitraltech Ltd. Techniques for percutaneous mitral valve replacement and sealing
WO2012012761A2 (en) * 2010-07-23 2012-01-26 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic valves
EP3342377B1 (en) 2010-09-10 2022-06-15 Boston Scientific Limited Valve replacement devices, delivery device for a valve replacement device and method of production of a valve replacement device
US10321998B2 (en) 2010-09-23 2019-06-18 Transmural Systems Llc Methods and systems for delivering prostheses using rail techniques
WO2012040655A2 (en) 2010-09-23 2012-03-29 Cardiaq Valve Technologies, Inc. Replacement heart valves, delivery devices and methods
US9579193B2 (en) 2010-09-23 2017-02-28 Transmural Systems Llc Methods and systems for delivering prostheses using rail techniques
EP2629699B1 (en) 2010-10-21 2017-01-04 Medtronic, Inc. Mitral bioprosthesis with low ventricular profile
CN103491900B (en) 2010-12-23 2017-03-01 托尔福公司 System for mitral valve repair and replacement
ES2585428T3 (en) 2011-01-21 2016-10-05 Obalon Therapeutics, Inc. Intragastric device
WO2012127309A1 (en) 2011-03-21 2012-09-27 Ontorfano Matteo Disk-based valve apparatus and method for the treatment of valve dysfunction
US9554897B2 (en) 2011-04-28 2017-01-31 Neovasc Tiara Inc. Methods and apparatus for engaging a valve prosthesis with tissue
US9308087B2 (en) 2011-04-28 2016-04-12 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
EP2520251A1 (en) 2011-05-05 2012-11-07 Symetis SA Method and Apparatus for Compressing Stent-Valves
EP3659553B1 (en) * 2011-05-16 2021-08-25 HLT, Inc. Inversion delivery device
US9522064B2 (en) 2011-05-16 2016-12-20 Hlt, Inc. Inversion delivery device and method for a prosthesis
US10500038B1 (en) 2011-05-20 2019-12-10 Tel Hashomer Medical Research Infrastructure And Services Ltd. Prosthetic mitral valve, and methods and devices for deploying the prosthetic mitral valve
WO2012177942A2 (en) 2011-06-21 2012-12-27 Hanson Gifford, Iii Prosthetic heart valve devices and associated systems and methods
EP2731550B1 (en) 2011-07-12 2016-02-24 Boston Scientific Scimed, Inc. Coupling system for a replacement valve
WO2013021374A2 (en) 2011-08-05 2013-02-14 Mitraltech Ltd. Techniques for percutaneous mitral valve replacement and sealing
US8852272B2 (en) 2011-08-05 2014-10-07 Mitraltech Ltd. Techniques for percutaneous mitral valve replacement and sealing
EP3417813B1 (en) 2011-08-05 2020-05-13 Cardiovalve Ltd Percutaneous mitral valve replacement
US20140324164A1 (en) 2011-08-05 2014-10-30 Mitraltech Ltd. Techniques for percutaneous mitral valve replacement and sealing
EP2741711B1 (en) 2011-08-11 2018-05-30 Tendyne Holdings, Inc. Improvements for prosthetic valves and related inventions
US9549817B2 (en) 2011-09-22 2017-01-24 Transmural Systems Llc Devices, systems and methods for repairing lumenal systems
EP4252714A3 (en) 2011-10-19 2023-12-20 Twelve, Inc. Device for heart valve replacement
US9039757B2 (en) 2011-10-19 2015-05-26 Twelve, Inc. Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods
US11202704B2 (en) 2011-10-19 2021-12-21 Twelve, Inc. Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods
US9655722B2 (en) 2011-10-19 2017-05-23 Twelve, Inc. Prosthetic heart valve devices, prosthetic mitral valves and associated systems and methods
US9763780B2 (en) * 2011-10-19 2017-09-19 Twelve, Inc. Devices, systems and methods for heart valve replacement
EP3984500A1 (en) 2011-10-19 2022-04-20 Twelve, Inc. Prosthetic heart valve devices
US9131926B2 (en) 2011-11-10 2015-09-15 Boston Scientific Scimed, Inc. Direct connect flush system
US8940014B2 (en) 2011-11-15 2015-01-27 Boston Scientific Scimed, Inc. Bond between components of a medical device
US8951243B2 (en) 2011-12-03 2015-02-10 Boston Scientific Scimed, Inc. Medical device handle
US9827092B2 (en) 2011-12-16 2017-11-28 Tendyne Holdings, Inc. Tethers for prosthetic mitral valve
US9510945B2 (en) 2011-12-20 2016-12-06 Boston Scientific Scimed Inc. Medical device handle
US9277993B2 (en) 2011-12-20 2016-03-08 Boston Scientific Scimed, Inc. Medical device delivery systems
WO2013112547A1 (en) 2012-01-25 2013-08-01 Boston Scientific Scimed, Inc. Valve assembly with a bioabsorbable gasket and a replaceable valve implant
EP3628247B1 (en) 2012-02-07 2022-08-10 Intervene, Inc. System for endoluminal valve creation
US9579198B2 (en) 2012-03-01 2017-02-28 Twelve, Inc. Hydraulic delivery systems for prosthetic heart valve devices and associated methods
ES2535295T3 (en) 2012-03-23 2015-05-08 Sorin Group Italia S.R.L. Folding valve prosthesis
CN107233145B (en) * 2012-05-16 2020-01-07 Hlt股份有限公司 Inverted delivery apparatus and method for prosthesis
AU2013264730B2 (en) 2012-05-20 2018-02-01 Tel Hashomer Medical Research Infrastructure And Services Ltd. Prosthetic mitral valve
US9345573B2 (en) 2012-05-30 2016-05-24 Neovasc Tiara Inc. Methods and apparatus for loading a prosthesis onto a delivery system
US9883941B2 (en) 2012-06-19 2018-02-06 Boston Scientific Scimed, Inc. Replacement heart valve
US20140031923A1 (en) * 2012-07-25 2014-01-30 Medtronic Vascular Galway Limited Trans-Aortic Surgical Syringe-Type Device for Deployment of a Prosthetic Valve
WO2014022124A1 (en) 2012-07-28 2014-02-06 Tendyne Holdings, Inc. Improved multi-component designs for heart valve retrieval device, sealing structures and stent assembly
US9675454B2 (en) 2012-07-30 2017-06-13 Tendyne Holdings, Inc. Delivery systems and methods for transcatheter prosthetic valves
EP2695586B1 (en) 2012-08-10 2019-05-08 Sorin Group Italia S.r.l. A valve prosthesis and kit
US20140067048A1 (en) 2012-09-06 2014-03-06 Edwards Lifesciences Corporation Heart Valve Sealing Devices
US10016276B2 (en) 2012-11-21 2018-07-10 Edwards Lifesciences Corporation Retaining mechanisms for prosthetic heart valves
CA2896333C (en) 2012-12-27 2021-01-12 Transcatheter Technologies Gmbh Apparatus and set for folding or unfolding a medical implant comprising a clamping mechanism
US9955990B2 (en) 2013-01-10 2018-05-01 Intervene, Inc. Systems and methods for endoluminal valve creation
US20150351906A1 (en) 2013-01-24 2015-12-10 Mitraltech Ltd. Ventricularly-anchored prosthetic valves
US9439763B2 (en) 2013-02-04 2016-09-13 Edwards Lifesciences Corporation Prosthetic valve for replacing mitral valve
US10583002B2 (en) 2013-03-11 2020-03-10 Neovasc Tiara Inc. Prosthetic valve with anti-pivoting mechanism
US20140277427A1 (en) 2013-03-14 2014-09-18 Cardiaq Valve Technologies, Inc. Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery
US9681951B2 (en) 2013-03-14 2017-06-20 Edwards Lifesciences Cardiaq Llc Prosthesis with outer skirt and anchors
US9730791B2 (en) 2013-03-14 2017-08-15 Edwards Lifesciences Cardiaq Llc Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery
US9232998B2 (en) 2013-03-15 2016-01-12 Cardiosolutions Inc. Trans-apical implant systems, implants and methods
US9289297B2 (en) 2013-03-15 2016-03-22 Cardiosolutions, Inc. Mitral valve spacer and system and method for implanting the same
US11224510B2 (en) 2013-04-02 2022-01-18 Tendyne Holdings, Inc. Prosthetic heart valve and systems and methods for delivering the same
US9486306B2 (en) 2013-04-02 2016-11-08 Tendyne Holdings, Inc. Inflatable annular sealing device for prosthetic mitral valve
US10463489B2 (en) 2013-04-02 2019-11-05 Tendyne Holdings, Inc. Prosthetic heart valve and systems and methods for delivering the same
US9572665B2 (en) 2013-04-04 2017-02-21 Neovasc Tiara Inc. Methods and apparatus for delivering a prosthetic valve to a beating heart
US10478293B2 (en) 2013-04-04 2019-11-19 Tendyne Holdings, Inc. Retrieval and repositioning system for prosthetic heart valve
CN105246431B (en) 2013-05-20 2018-04-06 托尔福公司 Implantable cardiac valve device, mitral valve repair device and related system and method
US9610159B2 (en) 2013-05-30 2017-04-04 Tendyne Holdings, Inc. Structural members for prosthetic mitral valves
EP3007651B1 (en) 2013-06-14 2020-08-05 Cardiosolutions, Inc. Mitral valve spacer
CN108814772B (en) 2013-06-25 2020-09-08 坦迪尼控股股份有限公司 Thrombus management and structural compliance features for prosthetic heart valves
US8870948B1 (en) 2013-07-17 2014-10-28 Cephea Valve Technologies, Inc. System and method for cardiac valve repair and replacement
EP3016595B1 (en) 2013-07-26 2018-12-19 Edwards Lifesciences CardiAQ LLC Systems for sealing openings in an anatomical wall
CN105555231B (en) 2013-08-01 2018-02-09 坦迪尼控股股份有限公司 External membrane of heart anchor and method
EP2835112B1 (en) 2013-08-08 2021-01-27 Sorin Group Italia S.r.l. Heart valve prosthesis
EP4098226A1 (en) 2013-08-30 2022-12-07 JenaValve Technology, Inc. Endoprosthesis comprising a radially collapsible frame and a prosthetic valve
US10195028B2 (en) 2013-09-10 2019-02-05 Edwards Lifesciences Corporation Magnetic retaining mechanisms for prosthetic valves
US10231613B2 (en) 2013-09-27 2019-03-19 Intervene, Inc. Visualization devices, systems, and methods for informing intravascular procedures on blood vessel valves
WO2015058039A1 (en) 2013-10-17 2015-04-23 Robert Vidlund Apparatus and methods for alignment and deployment of intracardiac devices
EP3656353A1 (en) 2013-10-28 2020-05-27 Tendyne Holdings, Inc. Prosthetic heart valve and systems for delivering the same
US9526611B2 (en) 2013-10-29 2016-12-27 Tendyne Holdings, Inc. Apparatus and methods for delivery of transcatheter prosthetic valves
KR102432831B1 (en) 2014-02-04 2022-08-12 이노브하르트 에세.에레.엘레. Prosthetic device for a heart valve
WO2015120122A2 (en) 2014-02-05 2015-08-13 Robert Vidlund Apparatus and methods for transfemoral delivery of prosthetic mitral valve
US9986993B2 (en) 2014-02-11 2018-06-05 Tendyne Holdings, Inc. Adjustable tether and epicardial pad system for prosthetic heart valve
CA2938614C (en) 2014-02-21 2024-01-23 Edwards Lifesciences Cardiaq Llc Delivery device for controlled deployement of a replacement valve
USD755384S1 (en) 2014-03-05 2016-05-03 Edwards Lifesciences Cardiaq Llc Stent
AU2015229708B2 (en) 2014-03-10 2019-08-15 Tendyne Holdings, Inc. Devices and methods for positioning and monitoring tether load for prosthetic mitral valve
US9320504B2 (en) 2014-03-24 2016-04-26 Intervene, Inc. Devices, systems, and methods for controlled hydrodissection of vessel walls
US20170014115A1 (en) 2014-03-27 2017-01-19 Transmural Systems Llc Devices and methods for closure of transvascular or transcameral access ports
USRE49792E1 (en) 2014-05-14 2024-01-09 Corcym S.R.L. Implant device and implantation kit
CA2948379C (en) 2014-05-19 2022-08-09 J. Brent Ratz Replacement mitral valve with annular flap
US9532870B2 (en) 2014-06-06 2017-01-03 Edwards Lifesciences Corporation Prosthetic valve for replacing a mitral valve
US10195026B2 (en) 2014-07-22 2019-02-05 Edwards Lifesciences Corporation Mitral valve anchoring
WO2016016899A1 (en) 2014-07-30 2016-02-04 Mitraltech Ltd. Articulatable prosthetic valve
US10058424B2 (en) 2014-08-21 2018-08-28 Edwards Lifesciences Corporation Dual-flange prosthetic valve frame
JP6625124B2 (en) 2014-10-13 2019-12-25 エイチエルティー， インコーポレイテッド Inversion delivery device and method for prosthesis
US9901445B2 (en) 2014-11-21 2018-02-27 Boston Scientific Scimed, Inc. Valve locking mechanism
CN107205817B (en) 2014-12-04 2020-04-03 爱德华兹生命科学公司 Percutaneous clamp for repairing heart valve
AU2015361260B2 (en) 2014-12-09 2020-04-23 Cephea Valve Technologies, Inc. Replacement cardiac valves and methods of use and manufacture
JP6728181B2 (en) 2014-12-16 2020-07-22 インタービーン・インコーポレイテッドＩＮＴＥＲＶＥＮＥ， Ｉｎｃｏｒｐｏｒａｔｅｄ Endovascular devices, systems and methods for controlled dissection of body cavities
CN107405195B (en) * 2015-01-07 2020-09-08 坦迪尼控股股份有限公司 Artificial mitral valve and apparatus and method for delivering artificial mitral valve
US10449043B2 (en) 2015-01-16 2019-10-22 Boston Scientific Scimed, Inc. Displacement based lock and release mechanism
US9861477B2 (en) 2015-01-26 2018-01-09 Boston Scientific Scimed Inc. Prosthetic heart valve square leaflet-leaflet stitch
US9788942B2 (en) 2015-02-03 2017-10-17 Boston Scientific Scimed Inc. Prosthetic heart valve having tubular seal
WO2016126524A1 (en) 2015-02-03 2016-08-11 Boston Scientific Scimed, Inc. Prosthetic heart valve having tubular seal
US9974651B2 (en) 2015-02-05 2018-05-22 Mitral Tech Ltd. Prosthetic valve with axially-sliding frames
CN107205818B (en) 2015-02-05 2019-05-10 卡迪尔维尔福股份有限公司 Artificial valve with the frame that slides axially
ES2877699T3 (en) 2015-02-05 2021-11-17 Tendyne Holdings Inc Prosthetic Heart Valve with Ligation and Expandable Epicardial Pad
US10426617B2 (en) 2015-03-06 2019-10-01 Boston Scientific Scimed, Inc. Low profile valve locking mechanism and commissure assembly
US10285809B2 (en) 2015-03-06 2019-05-14 Boston Scientific Scimed Inc. TAVI anchoring assist device
US10080652B2 (en) 2015-03-13 2018-09-25 Boston Scientific Scimed, Inc. Prosthetic heart valve having an improved tubular seal
JP6694948B2 (en) 2015-04-16 2020-05-20 テンダイン ホールディングス，インコーポレイテッド Device and method for delivery, repositioning and retrieval of a transcatheter prosthetic valve
US10064718B2 (en) 2015-04-16 2018-09-04 Edwards Lifesciences Corporation Low-profile prosthetic heart valve for replacing a mitral valve
US10010417B2 (en) 2015-04-16 2018-07-03 Edwards Lifesciences Corporation Low-profile prosthetic heart valve for replacing a mitral valve
US10441416B2 (en) 2015-04-21 2019-10-15 Edwards Lifesciences Corporation Percutaneous mitral valve replacement device
US10376363B2 (en) 2015-04-30 2019-08-13 Edwards Lifesciences Cardiaq Llc Replacement mitral valve, delivery system for replacement mitral valve and methods of use
EP3632378B1 (en) 2015-05-01 2024-05-29 JenaValve Technology, Inc. Device with reduced pacemaker rate in heart valve replacement
WO2018136959A1 (en) 2017-01-23 2018-07-26 Cephea Valve Technologies, Inc. Replacement mitral valves
EP4335415A3 (en) 2015-05-14 2024-05-29 Cephea Valve Technologies, Inc. Replacement mitral valves
US10849746B2 (en) 2015-05-14 2020-12-01 Cephea Valve Technologies, Inc. Cardiac valve delivery devices and systems
JP6755888B2 (en) 2015-05-14 2020-09-16 エドワーズ ライフサイエンシーズ コーポレイションＥｄｗａｒｄｓ Ｌｉｆｅｓｃｉｅｎｃｅｓ Ｃｏｒｐｏｒａｔｉｏｎ Heart valve sealing device and its delivery device
CA2990872C (en) 2015-06-22 2022-03-22 Edwards Lifescience Cardiaq Llc Actively controllable heart valve implant and methods of controlling same
US10092400B2 (en) 2015-06-23 2018-10-09 Edwards Lifesciences Cardiaq Llc Systems and methods for anchoring and sealing a prosthetic heart valve
WO2017004377A1 (en) 2015-07-02 2017-01-05 Boston Scientific Scimed, Inc. Adjustable nosecone
US10195392B2 (en) 2015-07-02 2019-02-05 Boston Scientific Scimed, Inc. Clip-on catheter
US10179041B2 (en) 2015-08-12 2019-01-15 Boston Scientific Scimed Icn. Pinless release mechanism
US10136991B2 (en) 2015-08-12 2018-11-27 Boston Scientific Scimed Inc. Replacement heart valve implant
CN111658234B (en) 2015-08-21 2023-03-10 托尔福公司 Implantable heart valve devices, mitral valve repair devices, and associated systems and methods
US10575951B2 (en) 2015-08-26 2020-03-03 Edwards Lifesciences Cardiaq Llc Delivery device and methods of use for transapical delivery of replacement mitral valve
US10117744B2 (en) 2015-08-26 2018-11-06 Edwards Lifesciences Cardiaq Llc Replacement heart valves and methods of delivery
US10350066B2 (en) 2015-08-28 2019-07-16 Edwards Lifesciences Cardiaq Llc Steerable delivery system for replacement mitral valve and methods of use
US10779940B2 (en) 2015-09-03 2020-09-22 Boston Scientific Scimed, Inc. Medical device handle
JP6869967B2 (en) 2015-09-15 2021-05-12 ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービスＴｈｅ Ｕｎｉｔｅｄ Ｓｔａｔｅｓ Ｏｆ Ａｍｅｒｉｃａ， Ａｓ Ｒｅｐｒｅｓｅｎｔｅｄ Ｂｙ Ｔｈｅ Ｓｅｃｒｅｔａｒｙ， Ｄｅｐａｒｔｍｅｎｔ Ｏｆ Ｈｅａｌｔｈ Ａｎｄ Ｈｕｍａｎ Ｓｅｒｖｉｃｅ Equipment and methods for performing percutaneous Glen and Fontan procedures
US10327894B2 (en) 2015-09-18 2019-06-25 Tendyne Holdings, Inc. Methods for delivery of prosthetic mitral valves
US10376364B2 (en) 2015-11-10 2019-08-13 Edwards Lifesciences Corporation Implant delivery capsule
US10470876B2 (en) 2015-11-10 2019-11-12 Edwards Lifesciences Corporation Transcatheter heart valve for replacing natural mitral valve
CA3005908A1 (en) 2015-12-03 2017-06-08 Tendyne Holdings, Inc. Frame features for prosthetic mitral valves
US10537453B2 (en) 2015-12-16 2020-01-21 Obalon Therapeutics, Inc. Intragastric device with expandable portions
CN108366859B (en) * 2015-12-28 2021-02-05 坦迪尼控股股份有限公司 Atrial capsular bag closure for prosthetic heart valves
CN113633435A (en) 2016-01-29 2021-11-12 内奥瓦斯克迪亚拉公司 Prosthetic valve for preventing outflow obstruction
US10342660B2 (en) 2016-02-02 2019-07-09 Boston Scientific Inc. Tensioned sheathing aids
US10531866B2 (en) 2016-02-16 2020-01-14 Cardiovalve Ltd. Techniques for providing a replacement valve and transseptal communication
US10835714B2 (en) 2016-03-21 2020-11-17 Edwards Lifesciences Corporation Multi-direction steerable handles for steering catheters
US10799675B2 (en) 2016-03-21 2020-10-13 Edwards Lifesciences Corporation Cam controlled multi-direction steerable handles
US11219746B2 (en) 2016-03-21 2022-01-11 Edwards Lifesciences Corporation Multi-direction steerable handles for steering catheters
US10646247B2 (en) 2016-04-01 2020-05-12 Intervene, Inc. Intraluminal tissue modifying systems and associated devices and methods
USD815744S1 (en) 2016-04-28 2018-04-17 Edwards Lifesciences Cardiaq Llc Valve frame for a delivery system
EP3448316B1 (en) 2016-04-29 2023-03-29 Medtronic Vascular Inc. Prosthetic heart valve devices with tethered anchors
US10470877B2 (en) 2016-05-03 2019-11-12 Tendyne Holdings, Inc. Apparatus and methods for anterior valve leaflet management
CN109475419B (en) 2016-05-13 2021-11-09 耶拿阀门科技股份有限公司 Heart valve prosthesis delivery systems and methods for delivering heart valve prostheses through guide sheaths and loading systems
US10583005B2 (en) 2016-05-13 2020-03-10 Boston Scientific Scimed, Inc. Medical device handle
US10201416B2 (en) 2016-05-16 2019-02-12 Boston Scientific Scimed, Inc. Replacement heart valve implant with invertible leaflets
US11039921B2 (en) 2016-06-13 2021-06-22 Tendyne Holdings, Inc. Sequential delivery of two-part prosthetic mitral valve
WO2017218877A1 (en) 2016-06-17 2017-12-21 Cephea Valve Technologies, Inc. Cardiac valve delivery devices and systems
EP3478224B1 (en) 2016-06-30 2022-11-02 Tendyne Holdings, Inc. Prosthetic heart valves and apparatus for delivery of same
US10973638B2 (en) 2016-07-07 2021-04-13 Edwards Lifesciences Corporation Device and method for treating vascular insufficiency
US11065116B2 (en) 2016-07-12 2021-07-20 Tendyne Holdings, Inc. Apparatus and methods for trans-septal retrieval of prosthetic heart valves
US10350062B2 (en) 2016-07-21 2019-07-16 Edwards Lifesciences Corporation Replacement heart valve prosthesis
USD800908S1 (en) 2016-08-10 2017-10-24 Mitraltech Ltd. Prosthetic valve element
CA3031187A1 (en) 2016-08-10 2018-02-15 Cardiovalve Ltd. Prosthetic valve with concentric frames
EP3500214A4 (en) 2016-08-19 2019-07-24 Edwards Lifesciences Corporation Steerable delivery system for replacement mitral valve and methods of use
AU2017314852B2 (en) 2016-08-26 2022-06-30 Edwards Lifesciences Corporation Multi-portion replacement heart valve prosthesis
US10758348B2 (en) 2016-11-02 2020-09-01 Edwards Lifesciences Corporation Supra and sub-annular mitral valve delivery system
US10653862B2 (en) 2016-11-07 2020-05-19 Edwards Lifesciences Corporation Apparatus for the introduction and manipulation of multiple telescoping catheters
CA3042588A1 (en) 2016-11-21 2018-05-24 Neovasc Tiara Inc. Methods and systems for rapid retraction of a transcatheter heart valve delivery system
US10905554B2 (en) 2017-01-05 2021-02-02 Edwards Lifesciences Corporation Heart valve coaptation device
AU2018203053B2 (en) 2017-01-23 2020-03-05 Cephea Valve Technologies, Inc. Replacement mitral valves
CN110392557A (en) 2017-01-27 2019-10-29 耶拿阀门科技股份有限公司 Heart valve simulation
US10702378B2 (en) 2017-04-18 2020-07-07 Twelve, Inc. Prosthetic heart valve device and associated systems and methods
US10575950B2 (en) 2017-04-18 2020-03-03 Twelve, Inc. Hydraulic systems for delivering prosthetic heart valve devices and associated methods
US11224511B2 (en) 2017-04-18 2022-01-18 Edwards Lifesciences Corporation Heart valve sealing devices and delivery devices therefor
US10433961B2 (en) 2017-04-18 2019-10-08 Twelve, Inc. Delivery systems with tethers for prosthetic heart valve devices and associated methods
BR112019021267A2 (en) 2017-04-18 2020-05-19 Edwards Lifesciences Corp heart valve sealing devices and release devices
US10799312B2 (en) 2017-04-28 2020-10-13 Edwards Lifesciences Corporation Medical device stabilizing apparatus and method of use
US10959846B2 (en) 2017-05-10 2021-03-30 Edwards Lifesciences Corporation Mitral valve spacer device
US10792151B2 (en) 2017-05-11 2020-10-06 Twelve, Inc. Delivery systems for delivering prosthetic heart valve devices and associated methods
US10646338B2 (en) 2017-06-02 2020-05-12 Twelve, Inc. Delivery systems with telescoping capsules for deploying prosthetic heart valve devices and associated methods
US10709591B2 (en) 2017-06-06 2020-07-14 Twelve, Inc. Crimping device and method for loading stents and prosthetic heart valves
WO2018226915A1 (en) 2017-06-08 2018-12-13 Boston Scientific Scimed, Inc. Heart valve implant commissure support structure
US10729541B2 (en) 2017-07-06 2020-08-04 Twelve, Inc. Prosthetic heart valve devices and associated systems and methods
US10786352B2 (en) 2017-07-06 2020-09-29 Twelve, Inc. Prosthetic heart valve devices and associated systems and methods
WO2019010321A1 (en) 2017-07-06 2019-01-10 Edwards Lifesciences Corporation Steerable rail delivery system
JP7216066B2 (en) 2017-07-13 2023-01-31 テンダイン ホールディングス，インコーポレイテッド Apparatus and methods for prosthetic heart valves and their delivery
EP3431040A1 (en) * 2017-07-20 2019-01-23 The Provost, Fellows, Foundation Scholars, and The Other Members of Board, of The College of The Holy and Undivided Trinity of Queen Elizabeth A stented valve
US10898325B2 (en) 2017-08-01 2021-01-26 Boston Scientific Scimed, Inc. Medical implant locking mechanism
US10888421B2 (en) 2017-09-19 2021-01-12 Cardiovalve Ltd. Prosthetic heart valve with pouch
US11793633B2 (en) 2017-08-03 2023-10-24 Cardiovalve Ltd. Prosthetic heart valve
US10575948B2 (en) 2017-08-03 2020-03-03 Cardiovalve Ltd. Prosthetic heart valve
US11246704B2 (en) 2017-08-03 2022-02-15 Cardiovalve Ltd. Prosthetic heart valve
US10537426B2 (en) 2017-08-03 2020-01-21 Cardiovalve Ltd. Prosthetic heart valve
EP3668449A1 (en) 2017-08-16 2020-06-24 Boston Scientific Scimed, Inc. Replacement heart valve commissure assembly
WO2019036810A1 (en) 2017-08-25 2019-02-28 Neovasc Tiara Inc. Sequentially deployed transcatheter mitral valve prosthesis
AU2018323900A1 (en) 2017-08-28 2020-02-27 Tendyne Holdings, Inc. Prosthetic heart valves with tether coupling features
US11051940B2 (en) 2017-09-07 2021-07-06 Edwards Lifesciences Corporation Prosthetic spacer device for heart valve
US11065117B2 (en) 2017-09-08 2021-07-20 Edwards Lifesciences Corporation Axisymmetric adjustable device for treating mitral regurgitation
US11040174B2 (en) 2017-09-19 2021-06-22 Edwards Lifesciences Corporation Multi-direction steerable handles for steering catheters
US11337804B2 (en) 2017-09-19 2022-05-24 Cardiovalve Ltd. Prosthetic valve with radially-deformable tissue anchors configured to restrict axial valve migration
US9895226B1 (en) 2017-10-19 2018-02-20 Mitral Tech Ltd. Techniques for use with prosthetic valve leaflets
GB201720803D0 (en) 2017-12-13 2018-01-24 Mitraltech Ltd Prosthetic Valve and delivery tool therefor
US10136993B1 (en) 2018-01-09 2018-11-27 Edwards Lifesciences Corporation Native valve repair devices and procedures
US10076415B1 (en) 2018-01-09 2018-09-18 Edwards Lifesciences Corporation Native valve repair devices and procedures
US10105222B1 (en) 2018-01-09 2018-10-23 Edwards Lifesciences Corporation Native valve repair devices and procedures
US10238493B1 (en) 2018-01-09 2019-03-26 Edwards Lifesciences Corporation Native valve repair devices and procedures
US10111751B1 (en) 2018-01-09 2018-10-30 Edwards Lifesciences Corporation Native valve repair devices and procedures
US10245144B1 (en) 2018-01-09 2019-04-02 Edwards Lifesciences Corporation Native valve repair devices and procedures
US10231837B1 (en) 2018-01-09 2019-03-19 Edwards Lifesciences Corporation Native valve repair devices and procedures
US10973639B2 (en) 2018-01-09 2021-04-13 Edwards Lifesciences Corporation Native valve repair devices and procedures
MX2020005397A (en) 2018-01-09 2020-08-17 Edwards Lifesciences Corp Native valve repair devices and procedures.
US10123873B1 (en) 2018-01-09 2018-11-13 Edwards Lifesciences Corporation Native valve repair devices and procedures
US10159570B1 (en) 2018-01-09 2018-12-25 Edwards Lifesciences Corporation Native valve repair devices and procedures
GB201800399D0 (en) 2018-01-10 2018-02-21 Mitraltech Ltd Temperature-control during crimping of an implant
WO2019144071A1 (en) 2018-01-19 2019-07-25 Boston Scientific Scimed, Inc. Medical device delivery system with feedback loop
WO2019144069A2 (en) 2018-01-19 2019-07-25 Boston Scientific Scimed, Inc. Inductance mode deployment sensors for transcatheter valve system
CN111818877B (en) 2018-01-25 2023-12-22 爱德华兹生命科学公司 Delivery system for assisting in recapture and repositioning of replacement valves after deployment
WO2019157156A1 (en) 2018-02-07 2019-08-15 Boston Scientific Scimed, Inc. Medical device delivery system with alignment feature
WO2019165394A1 (en) 2018-02-26 2019-08-29 Boston Scientific Scimed, Inc. Embedded radiopaque marker in adaptive seal
US11051934B2 (en) 2018-02-28 2021-07-06 Edwards Lifesciences Corporation Prosthetic mitral valve with improved anchors and seal
WO2019195860A2 (en) 2018-04-04 2019-10-10 Vdyne, Llc Devices and methods for anchoring transcatheter heart valve
US11389297B2 (en) 2018-04-12 2022-07-19 Edwards Lifesciences Corporation Mitral valve spacer device
US11207181B2 (en) 2018-04-18 2021-12-28 Edwards Lifesciences Corporation Heart valve sealing devices and delivery devices therefor
EP3793478A1 (en) 2018-05-15 2021-03-24 Boston Scientific Scimed, Inc. Replacement heart valve commissure assembly
JP7109657B2 (en) 2018-05-23 2022-07-29 コーシム・ソチエタ・ア・レスポンサビリタ・リミタータ heart valve prosthesis
WO2019241477A1 (en) 2018-06-13 2019-12-19 Boston Scientific Scimed, Inc. Replacement heart valve delivery device
US10779937B2 (en) 2018-06-22 2020-09-22 Vdyne, Inc. Transcatheter heart valve with plication window and tissue anchors
US10779946B2 (en) 2018-09-17 2020-09-22 Cardiovalve Ltd. Leaflet-testing apparatus
US10595994B1 (en) 2018-09-20 2020-03-24 Vdyne, Llc Side-delivered transcatheter heart valve replacement
US10321995B1 (en) 2018-09-20 2019-06-18 Vdyne, Llc Orthogonally delivered transcatheter heart valve replacement
US11278437B2 (en) 2018-12-08 2022-03-22 Vdyne, Inc. Compression capable annular frames for side delivery of transcatheter heart valve replacement
US11344413B2 (en) 2018-09-20 2022-05-31 Vdyne, Inc. Transcatheter deliverable prosthetic heart valves and methods of delivery
US11071627B2 (en) 2018-10-18 2021-07-27 Vdyne, Inc. Orthogonally delivered transcatheter heart valve frame for valve in valve prosthesis
US10945844B2 (en) 2018-10-10 2021-03-16 Edwards Lifesciences Corporation Heart valve sealing devices and delivery devices therefor
US11109969B2 (en) 2018-10-22 2021-09-07 Vdyne, Inc. Guidewire delivery of transcatheter heart valve
US11737872B2 (en) 2018-11-08 2023-08-29 Neovasc Tiara Inc. Ventricular deployment of a transcatheter mitral valve prosthesis
US11241312B2 (en) 2018-12-10 2022-02-08 Boston Scientific Scimed, Inc. Medical device delivery system including a resistance member
US10653522B1 (en) 2018-12-20 2020-05-19 Vdyne, Inc. Proximal tab for side-delivered transcatheter heart valve prosthesis
US11253359B2 (en) 2018-12-20 2022-02-22 Vdyne, Inc. Proximal tab for side-delivered transcatheter heart valves and methods of delivery
US11273032B2 (en) 2019-01-26 2022-03-15 Vdyne, Inc. Collapsible inner flow control component for side-deliverable transcatheter heart valve prosthesis
US11185409B2 (en) 2019-01-26 2021-11-30 Vdyne, Inc. Collapsible inner flow control component for side-delivered transcatheter heart valve prosthesis
AU2020223047A1 (en) 2019-02-14 2021-08-19 Edwards Lifesciences Corporation Heart valve sealing devices and delivery devices therefor
EP4364706A2 (en) 2019-03-05 2024-05-08 Vdyne, Inc. Tricuspid regurgitation control devices for orthogonal transcatheter heart valve prosthesis
CN113747863A (en) 2019-03-08 2021-12-03 内奥瓦斯克迪亚拉公司 Retrievable prosthesis delivery system
US11173027B2 (en) 2019-03-14 2021-11-16 Vdyne, Inc. Side-deliverable transcatheter prosthetic valves and methods for delivering and anchoring the same
US10631983B1 (en) 2019-03-14 2020-04-28 Vdyne, Inc. Distal subannular anchoring tab for side-delivered transcatheter valve prosthesis
US10758346B1 (en) 2019-03-14 2020-09-01 Vdyne, Inc. A2 clip for side-delivered transcatheter mitral valve prosthesis
US11076956B2 (en) 2019-03-14 2021-08-03 Vdyne, Inc. Proximal, distal, and anterior anchoring tabs for side-delivered transcatheter mitral valve prosthesis
WO2020206012A1 (en) 2019-04-01 2020-10-08 Neovasc Tiara Inc. Controllably deployable prosthetic valve
US11491006B2 (en) 2019-04-10 2022-11-08 Neovasc Tiara Inc. Prosthetic valve with natural blood flow
JP2022530764A (en) 2019-05-04 2022-07-01 ブイダイン，インコーポレイテッド Tightening device and method for deploying a laterally delivered artificial heart valve with a native annulus.
US11439504B2 (en) 2019-05-10 2022-09-13 Boston Scientific Scimed, Inc. Replacement heart valve with improved cusp washout and reduced loading
WO2020236931A1 (en) 2019-05-20 2020-11-26 Neovasc Tiara Inc. Introducer with hemostasis mechanism
US11311376B2 (en) 2019-06-20 2022-04-26 Neovase Tiara Inc. Low profile prosthetic mitral valve
CA3152042A1 (en) 2019-08-20 2021-02-25 Vdyne, Inc. Delivery and retrieval devices and methods for side-deliverable transcatheter prosthetic valves
AU2020337235A1 (en) 2019-08-26 2022-03-24 Vdyne, Inc. Side-deliverable transcatheter prosthetic valves and methods for delivering and anchoring the same
US11648110B2 (en) 2019-12-05 2023-05-16 Tendyne Holdings, Inc. Braided anchor for mitral valve
US11648114B2 (en) 2019-12-20 2023-05-16 Tendyne Holdings, Inc. Distally loaded sheath and loading funnel
US11234813B2 (en) 2020-01-17 2022-02-01 Vdyne, Inc. Ventricular stability elements for side-deliverable prosthetic heart valves and methods of delivery
US11951002B2 (en) 2020-03-30 2024-04-09 Tendyne Holdings, Inc. Apparatus and methods for valve and tether fixation
WO2021262785A1 (en) 2020-06-23 2021-12-30 Intervene, Inc. Endovascular valve formation system with imaging capability
WO2022039853A1 (en) 2020-08-19 2022-02-24 Tendyne Holdings, Inc. Fully-transseptal apical pad with pulley for tensioning
CN113679512A (en) * 2021-08-11 2021-11-23 上海傲流医疗科技有限公司 Repair device for treating tricuspid valve regurgitation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040186563A1 (en) * 2003-03-18 2004-09-23 Lobbi Mario M. Minimally-invasive heart valve with cusp positioners
US6893459B1 (en) * 2000-09-20 2005-05-17 Ample Medical, Inc. Heart valve annulus device and method of using same

Family Cites Families (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3143742A (en) * 1963-03-19 1964-08-11 Surgitool Inc Prosthetic sutureless heart valve
US3686740A (en) * 1970-06-19 1972-08-29 Donald P Shiley Method of assemblying a sutureless heart valve
US3731955A (en) * 1971-09-24 1973-05-08 A Borsum Push-pull connector having a shear-resistant locking ring
AR229309A1 (en) * 1983-04-20 1983-07-15 Barone Hector Daniel MOUNT FOR CARDIAC VALVES
CA1232407A (en) * 1983-06-23 1988-02-09 David K. Walker Bubble heart valve
US5197979A (en) * 1990-09-07 1993-03-30 Baxter International Inc. Stentless heart valve and holder
DE69529338T3 (en) * 1994-07-08 2007-05-31 Ev3 Inc., Plymouth Intravascular filter device
US5554185A (en) * 1994-07-18 1996-09-10 Block; Peter C. Inflatable prosthetic cardiovascular valve for percutaneous transluminal implantation of same
US6402780B2 (en) * 1996-02-23 2002-06-11 Cardiovascular Technologies, L.L.C. Means and method of replacing a heart valve in a minimally invasive manner
US5885228A (en) * 1996-05-08 1999-03-23 Heartport, Inc. Valve sizer and method of use
US5855601A (en) * 1996-06-21 1999-01-05 The Trustees Of Columbia University In The City Of New York Artificial heart valve and method and device for implanting the same
DE69721550T2 (en) 1996-09-13 2004-03-18 Medtronic, Inc., Minneapolis HEART VALVE PROSTHESIS WITH SEWING PART OF NON-SQUARE RADIAL WIDTH
US5984959A (en) * 1997-09-19 1999-11-16 United States Surgical Heart valve replacement tools and procedures
US6530952B2 (en) * 1997-12-29 2003-03-11 The Cleveland Clinic Foundation Bioprosthetic cardiovascular valve system
US6074418A (en) * 1998-04-20 2000-06-13 St. Jude Medical, Inc. Driver tool for heart valve prosthesis fasteners
US7569062B1 (en) * 1998-07-15 2009-08-04 St. Jude Medical, Inc. Mitral and tricuspid valve repair
US6165183A (en) * 1998-07-15 2000-12-26 St. Jude Medical, Inc. Mitral and tricuspid valve repair
US6736845B2 (en) * 1999-01-26 2004-05-18 Edwards Lifesciences Corporation Holder for flexible heart valve
US6896690B1 (en) * 2000-01-27 2005-05-24 Viacor, Inc. Cardiac valve procedure methods and devices
US6425916B1 (en) * 1999-02-10 2002-07-30 Michi E. Garrison Methods and devices for implanting cardiac valves
US7811296B2 (en) * 1999-04-09 2010-10-12 Evalve, Inc. Fixation devices for variation in engagement of tissue
US7563267B2 (en) * 1999-04-09 2009-07-21 Evalve, Inc. Fixation device and methods for engaging tissue
US6790229B1 (en) * 1999-05-25 2004-09-14 Eric Berreklouw Fixing device, in particular for fixing to vascular wall tissue
US6287339B1 (en) * 1999-05-27 2001-09-11 Sulzer Carbomedics Inc. Sutureless heart valve prosthesis
US6231561B1 (en) * 1999-09-20 2001-05-15 Appriva Medical, Inc. Method and apparatus for closing a body lumen
US8579966B2 (en) * 1999-11-17 2013-11-12 Medtronic Corevalve Llc Prosthetic valve for transluminal delivery
US6458153B1 (en) * 1999-12-31 2002-10-01 Abps Venture One, Ltd. Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof
US6409759B1 (en) * 1999-12-30 2002-06-25 St. Jude Medical, Inc. Harvested tissue heart valve with sewing rim
EP1251804B1 (en) * 2000-01-27 2008-07-02 3F Therapeutics, Inc Prosthetic heart valve
US6551344B2 (en) * 2000-04-26 2003-04-22 Ev3 Inc. Septal defect occluder
US6676698B2 (en) * 2000-06-26 2004-01-13 Rex Medicol, L.P. Vascular device with valve for approximating vessel wall
WO2002019951A1 (en) * 2000-09-07 2002-03-14 Viacor, Inc. Fixation band for affixing a prosthetic heart valve to tissue
US8784482B2 (en) 2000-09-20 2014-07-22 Mvrx, Inc. Method of reshaping a heart valve annulus using an intravascular device
US8956407B2 (en) * 2000-09-20 2015-02-17 Mvrx, Inc. Methods for reshaping a heart valve annulus using a tensioning implant
US20060106456A9 (en) * 2002-10-01 2006-05-18 Ample Medical, Inc. Devices, systems, and methods for reshaping a heart valve annulus
WO2004030568A2 (en) 2002-10-01 2004-04-15 Ample Medical, Inc. Device and method for repairing a native heart valve leaflet
WO2004030570A2 (en) 2002-10-01 2004-04-15 Ample Medical, Inc. Devices for retaining native heart valve leaflet
US6974476B2 (en) * 2003-05-05 2005-12-13 Rex Medical, L.P. Percutaneous aortic valve
US6733525B2 (en) * 2001-03-23 2004-05-11 Edwards Lifesciences Corporation Rolled minimally-invasive heart valves and methods of use
US7374571B2 (en) * 2001-03-23 2008-05-20 Edwards Lifesciences Corporation Rolled minimally-invasive heart valves and methods of manufacture
WO2003007951A1 (en) * 2001-07-17 2003-01-30 N-Gene Research Laboratories Inc. A synergistic pharmaceutical combination for the prevention or treatment of diabetes
FR2828091B1 (en) * 2001-07-31 2003-11-21 Seguin Jacques ASSEMBLY ALLOWING THE PLACEMENT OF A PROTHETIC VALVE IN A BODY DUCT
FR2828263B1 (en) 2001-08-03 2007-05-11 Philipp Bonhoeffer DEVICE FOR IMPLANTATION OF AN IMPLANT AND METHOD FOR IMPLANTATION OF THE DEVICE
US7097659B2 (en) * 2001-09-07 2006-08-29 Medtronic, Inc. Fixation band for affixing a prosthetic heart valve to tissue
CA2455444A1 (en) * 2001-10-01 2003-04-10 Ample Medical, Inc. Methods and devices for heart valve treatments
US7033390B2 (en) * 2002-01-02 2006-04-25 Medtronic, Inc. Prosthetic heart valve system
US7189258B2 (en) * 2002-01-02 2007-03-13 Medtronic, Inc. Heart valve system
US6974464B2 (en) * 2002-02-28 2005-12-13 3F Therapeutics, Inc. Supportless atrioventricular heart valve and minimally invasive delivery systems thereof
AU2003230938A1 (en) 2002-04-16 2003-11-03 Viacor, Inc. Fixation band for affixing a prosthetic heart valve to tissue
US7041132B2 (en) * 2002-08-16 2006-05-09 3F Therapeutics, Inc, Percutaneously delivered heart valve and delivery means thereof
AU2003268220B8 (en) * 2002-08-28 2010-01-21 Hlt, Inc. Method and device for treating diseased valve
WO2004028558A1 (en) 2002-09-27 2004-04-08 Takeda Pharmaceutical Company Limited Preventives/remedies for neurodegenerative disease
WO2004043293A2 (en) 2002-11-13 2004-05-27 Viacor, Inc. Cardiac valve procedure methods and devices
US20040097979A1 (en) * 2002-11-14 2004-05-20 Oleg Svanidze Aortic valve implantation device
US8551162B2 (en) * 2002-12-20 2013-10-08 Medtronic, Inc. Biologically implantable prosthesis
DE10313004B3 (en) * 2003-03-24 2005-01-20 Siemens Ag Modulation method, mode providing method and receiving unit for a magnetic resonance apparatus
WO2004089250A1 (en) * 2003-03-30 2004-10-21 Fidel Realyvasquez Apparatus and methods for valve repair
US7201772B2 (en) * 2003-07-08 2007-04-10 Ventor Technologies, Ltd. Fluid flow prosthetic device
US7429269B2 (en) * 2003-07-08 2008-09-30 Ventor Technologies Ltd. Aortic prosthetic devices
US7621948B2 (en) * 2003-07-21 2009-11-24 The Trustees Of The University Of Pennsylvania Percutaneous heart valve
US8021421B2 (en) * 2003-08-22 2011-09-20 Medtronic, Inc. Prosthesis heart valve fixturing device
WO2005046528A1 (en) 2003-10-06 2005-05-26 3F Therapeutics, Inc. Minimally invasive valve replacement system
US20050096738A1 (en) * 2003-10-06 2005-05-05 Cali Douglas S. Minimally invasive valve replacement system
US7959666B2 (en) * 2003-12-23 2011-06-14 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a heart valve
US8343213B2 (en) * 2003-12-23 2013-01-01 Sadra Medical, Inc. Leaflet engagement elements and methods for use thereof
US8828078B2 (en) * 2003-12-23 2014-09-09 Sadra Medical, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
US7329279B2 (en) * 2003-12-23 2008-02-12 Sadra Medical, Inc. Methods and apparatus for endovascularly replacing a patient's heart valve
US7311730B2 (en) * 2004-02-13 2007-12-25 Shlomo Gabbay Support apparatus and heart valve prosthesis for sutureless implantation
NL1025830C2 (en) * 2004-03-26 2005-02-22 Eric Berreklouw Prosthesis e.g. heart valve secured in place by ring with shape memory material anchor, includes anchor temperature control system
US8012201B2 (en) * 2004-05-05 2011-09-06 Direct Flow Medical, Inc. Translumenally implantable heart valve with multiple chamber formed in place support
US6951571B1 (en) * 2004-09-30 2005-10-04 Rohit Srivastava Valve implanting device
WO2006055982A2 (en) * 2004-11-22 2006-05-26 Avvrx Ring-shaped valve prosthesis attachment device
US7569071B2 (en) * 2005-09-21 2009-08-04 Boston Scientific Scimed, Inc. Venous valve, system, and method with sinus pocket
EP2012712B1 (en) * 2006-04-29 2016-02-10 Medtronic, Inc. Guide shields for multiple component prosthetic heart valve assemblies
WO2007130881A2 (en) * 2006-04-29 2007-11-15 Arbor Surgical Technologies, Inc. Multiple component prosthetic heart valve assemblies and apparatus and methods for delivering them
US20080033541A1 (en) * 2006-08-02 2008-02-07 Daniel Gelbart Artificial mitral valve
US7753949B2 (en) * 2007-02-23 2010-07-13 The Trustees Of The University Of Pennsylvania Valve prosthesis systems and methods
US8070802B2 (en) * 2007-02-23 2011-12-06 The Trustees Of The University Of Pennsylvania Mitral valve system

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6893459B1 (en) * 2000-09-20 2005-05-17 Ample Medical, Inc. Heart valve annulus device and method of using same
US20040186563A1 (en) * 2003-03-18 2004-09-23 Lobbi Mario M. Minimally-invasive heart valve with cusp positioners

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EP2114305A2 (en) 2009-11-11
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US7753949B2 (en) 2010-07-13
US20080208332A1 (en) 2008-08-28
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JP2010518977A (en) 2010-06-03
AU2008218947B2 (en) 2013-02-07
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US20080208328A1 (en) 2008-08-28
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WO2008103497A2 (en) 2008-08-28
WO2008103497A3 (en) 2009-12-30

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