EP2051698A1 - Liposomaler komplex aus natriumcarboxymethylbeta-glucan - Google Patents

Liposomaler komplex aus natriumcarboxymethylbeta-glucan

Info

Publication number
EP2051698A1
EP2051698A1 EP06780590A EP06780590A EP2051698A1 EP 2051698 A1 EP2051698 A1 EP 2051698A1 EP 06780590 A EP06780590 A EP 06780590A EP 06780590 A EP06780590 A EP 06780590A EP 2051698 A1 EP2051698 A1 EP 2051698A1
Authority
EP
European Patent Office
Prior art keywords
sodium carboxymethyl
beta glucan
carboxymethyl beta
liposomal complex
complex
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06780590A
Other languages
English (en)
French (fr)
Inventor
Luigi Mercuri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mibelle AG
DMG Italia SRL
Original Assignee
Mibelle AG
DMG Italia SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mibelle AG, DMG Italia SRL filed Critical Mibelle AG
Publication of EP2051698A1 publication Critical patent/EP2051698A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers

Definitions

  • Glucan preparations have been shown to be active at very low concentrations. WoIk et al. found a significant acceleration in wound healing by topical application of a glucan preparation at 0.01% [3].
  • nanoparticles agents [12].
  • the technique of high pressure homogenization permits the industrial production of high quality vesicle dispersions for cosmetic and other uses.
  • the lecithin dispersion is homogenized at 1200 bar 4 times using a Microfluidizer to prepare liposomes .
  • the particle size(s) of the liposomes is (are) analyzed with a photon correlation spectrometer.
  • the average particle size zav was 40 nm.
  • 1 1 of the CM-Glucan solution is mixed with 1 1 of the liposomes.
  • the mixture is homogenized again at 1200 bar 2 times using a Microfluidizer .
  • the final preparation forms a liposomal CM-Glucan complex with a particle size of 60 +/- 30 nm.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
EP06780590A 2006-07-18 2006-07-18 Liposomaler komplex aus natriumcarboxymethylbeta-glucan Withdrawn EP2051698A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IT2006/000543 WO2008010241A1 (en) 2006-07-18 2006-07-18 A liposomal complex of sodium carboxymethyl beta-glucan

Publications (1)

Publication Number Publication Date
EP2051698A1 true EP2051698A1 (de) 2009-04-29

Family

ID=37763389

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06780590A Withdrawn EP2051698A1 (de) 2006-07-18 2006-07-18 Liposomaler komplex aus natriumcarboxymethylbeta-glucan

Country Status (2)

Country Link
EP (1) EP2051698A1 (de)
WO (1) WO2008010241A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6189749B2 (ja) * 2010-06-23 2017-08-30 ブライトサイド イノベーションズ，インコーポレイティド レシチン担体小胞とその作製方法
IT1401083B1 (it) * 2010-07-27 2013-07-12 Pasquali S R L Composizione per il trattamento e la prevenzione dell'herpes simplex labiale.
ITRM20120275A1 (it) * 2012-06-13 2013-12-14 Noos S R L Associazione di resveratrolo e carbossimetilglucano.
AU2015228775B2 (en) 2014-03-13 2020-04-02 Procare Health Iberia, S.L. Topical compositions comprising extract of Coriolus versicolor for autoimmunity enhancement
CA3163788A1 (en) 2019-12-06 2021-06-10 JLABS Beauty LLC Topical compositions containing rose oil and cannabidiol and methods of making and using the same
AU2021276680A1 (en) 2020-05-22 2023-01-19 Ilera Derm LLC Compositions for treating acne and dermatological conditions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19715478A1 (de) * 1997-04-10 1998-10-15 Lancaster Group Gmbh Kosmetisches und dermatologisches Mittel auf Basis von hartmagnetischen Teilchen
CH693981A5 (de) * 1999-07-12 2004-05-28 Mibelle Ag Cosmetics Retinoidhaltige Hautpflegemittel zur kosmetischen und/oder therapeutischen Behandlung der Haut.
EP1421974B1 (de) * 2002-06-10 2006-12-06 D.M.G. Italia Srl Carboxy Methyl Beta-1,3 Glucan enthaltende ophthalmische Lösung
CH702571B1 (de) * 2003-04-30 2011-07-29 Mibelle Ag Cosmetics Kosmetische Hautbehandlungsmittel und kosmetische Wirkstoffkombination zum Schutz gegen frühzeitige Hautalterung.
DE102005033954A1 (de) * 2005-07-20 2007-01-25 Switzerland c/o Laris Fiduciara Sca, Ethios Zusammensetzung, die eine liposomale Dispersion von SiO2-Nanopartikeln und ein ß-1,3-verknüpftes Glucanetherderivat umfasst

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2008010241A1 *

Also Published As

Publication number Publication date
WO2008010241A1 (en) 2008-01-24

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