EP2048081B1 - Automatische Abgabevorrichtung für Radiopharmazeutika - Google Patents

Automatische Abgabevorrichtung für Radiopharmazeutika Download PDF

Info

Publication number
EP2048081B1
EP2048081B1 EP20070019673 EP07019673A EP2048081B1 EP 2048081 B1 EP2048081 B1 EP 2048081B1 EP 20070019673 EP20070019673 EP 20070019673 EP 07019673 A EP07019673 A EP 07019673A EP 2048081 B1 EP2048081 B1 EP 2048081B1
Authority
EP
European Patent Office
Prior art keywords
syringe
radiopharmaceuticals
moving module
axis moving
automated dispenser
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Not-in-force
Application number
EP20070019673
Other languages
English (en)
French (fr)
Other versions
EP2048081A1 (de
Inventor
Ming-Hsin Lee
Wuu-Jyh Lin
Tain-Shi Zen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Nuclear Energy Research
Original Assignee
Institute of Nuclear Energy Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institute of Nuclear Energy Research filed Critical Institute of Nuclear Energy Research
Priority to EP20070019673 priority Critical patent/EP2048081B1/de
Priority to DE200760005945 priority patent/DE602007005945D1/de
Publication of EP2048081A1 publication Critical patent/EP2048081A1/de
Application granted granted Critical
Publication of EP2048081B1 publication Critical patent/EP2048081B1/de
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like

Definitions

  • the invention is related to an automated dispenser for radiopharmaceuticals. Especially it refers to a situation that hand contact with radiopharmaceuticals is avoided and exposure to radioactive materials is reduced for operators.
  • the main objective for the invention is to provide an automated dispenser for radiopharmaceuticals, so it automatically dispenses high-dose radiopharmaceuticals from bottles into sterile syringes and reduces direct exposure to radioactive environment for operators.
  • Another objective for the invention is to provide an automated dispenser for radiopharmaceuticals, so it uses sterile syringes to dispense radionuclides into bottles for chemical reactions or other uses.
  • Another objective for the invention is to provide an automated dispenser for radiopharmaceuticals, so it is suitable for withdrawing highly toxic and highly contagious pharmaceuticals and demonstrates value of extensive applications.
  • the invention is defined by the features of claim 1.
  • the syringe clamp driven by the Z-axis moving module can ascend or descend along the direction perpendicular to Z-axis.
  • the Z-axis moving module driven by the Y-axis moving module slides back and forth in the direction of Y-axis in a preset horizontal plane.
  • the Y-axis moving module driven by the X-axis moving module slides back and forth in the direction of X-axis in the horizontal plane.
  • the syringe clamp is associated with the Z-axis moving module through a rotation module. Driven by the rotation module, the syringe clamp rotates against the Z-axis moving module.
  • the syringe is located inside a lead shield which periphery has a flange in its middle section.
  • the syringe clamp has a groove corresponding to the flange position. Through the shifting of the groove against the flange back and forth, engagement or disengagement can be achieved.
  • the invention mainly includes: a platform 1, a moving mechanism 2, a syringe driving mechanism 3, a syringe holder 4 and a bottle holder 5.
  • the platform 1 has a supporting plane on top.
  • the moving mechanism 2 is ' composed of an X-axis moving module 21, a Y-axis moving module 22, a Z-axis moving module 23 and a rotation module 24.
  • TheX-axis moving module 21 is located on the supporting plane of the platform 1.
  • a power source 211 (such as a step motor) drives a shifting platform 212 to move along a preset straight track (assuming it is X-axis).
  • the Y-axis moving module 22 is located on the shifting platform 212 and uses a power source 221 (such as a step motor) to drive a shifting platform 222 to move along a straight track perpendicular to X-axis (assuming it is Y-axis).
  • the rotation module 24 is located on the shifting platform 222 and uses a power source 241 to drive a rotation base 242 to turn around the axis parallel to Y-axis.
  • the Z-axis moving module 23 is located on the rotation base 242 and uses a power source 231 (such as a step motor) to drive a shifting base 232 to move along a straight track (assuming it is Z-axis) perpendicular to X-axis and Y-axis.
  • the shifting base 232 has a syringe clamp 233.
  • the syringe clamp 233 has a clamping slot 234 with an opening.
  • the syringe driving mechanism 3 is associated with the shifting base 232, and uses a power source 31 (such as a step motor) to drive a driving rod 32 to move along a straight track parallel to Z-axis, and makes the driving rod 32 to connect with a moving device 33 which bottom has a clamping slot 34 with an opening.
  • the syringe holder 4 is located at one side of the moving mechanism 2 for accommodating a plural number of syringes 42.
  • the syringes 42 are located inside a lead shield 41.
  • the lead shield 41 has a flange 411 in the middle section of its periphery.
  • a flange 411 At the bottom of the syringe holder 4 there are a plural number of syringe cylinders corresponding to the syringe 42 position. So when the syringe 42 is positioned at the syringe holder 4, each cylinder is placed outside the syringe.
  • the bottle holder 5 is located beside the moving mechanism 2 and the syringe holder 4 and mainly used to hold bottles for radiopharmaceuticals. The bottles are placed and fixed in a designated lead box 51 and have their mouth down for the convenience of withdrawing drug.
  • the moving mechanism 2 through digital system control makes X-axis moving module 21, Y-axis moving module 22 and Z-axis moving module 23 to shift in a proper distance and makes the clamping slot 234 for the syringe clamp 233 to put on the flange 411 of the lead shield 41, while the clamping slot 34 of the syringe driving mechanism 3 can be put on the drug-withdrawing rod of the syringe 42. Then the shifting base 232 of the Z-axis moving module 23 rises to make the lead shield 41 and the syringe 42 to detach from the syringe holder 4.
  • the X-axis moving module 21 and the Y-axis moving module 22 drive the syringe 42 to shift under the lead box 51 for the bottle holder 5.
  • the rotation module 24 drives the syringe 42 to rotate in 180 degrees and make the needle of the syringe 42 upward.
  • the shifting base 232 of the Z-axis moving module 23 rises again to make the syringe 42 needle to insert into the drug bottle.
  • the driving rod 32 for the syringe driving mechanism 3 drives the moving device 33 and the clamping slot 34 drives the drug-withdrawing rod of the syringe 42 to withdraw radiopharmaceuticals from the bottle.
  • the shifting base 232 of the Z-axis moving module 23 descends to make the syringe 42 needle to detach from the drug bottle. Then X-axis moving module 21 and Y-axis moving module 22 drive the syringe 42 to shift above the syringe holder 4.
  • the rotation module 24 drives the syringe 42 to rotate in 180 degrees and makes the syringe 42 needles downward.
  • the shifting base 232 of the Z-axis moving module 23 descends to position the syringe 42 into the syringe holder 4 and the needle extends into the cylinder to complete the drug dispensing process.
  • the automated dispenser for radiopharmaceuticals in the invention can prevent operators from contacting radiopharmaceuticals and reduce exposure to radiation.
  • the invention is an innovative and advanced achievement. The above content is only an explanation for a preferred embodiment for the invention.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Claims (9)

  1. Ein automatischer Spender für Radiopharmazeutikum bestehend aus: einem Ständer (1) mit einer Stützfläche auf der Oberseite; einem Medikamentbehälter auf einer Seite des Ständers; einem Bewegungsmechanismus (2), der aus einem Bewegungsmodul an der X-Achse (21), einem Bewegungsmodul an der Y-Achse (22) und einem Bewegungsmodul an der Z-Achse (23) besteht. An diesem Modul kann die Halterung einer Injektionsspritze (233) bewegt werden, eine Injektionsspritze (42) gehalten werden und in einem dreidimensionalen Raum vor und zurückbewegt werden. Die Injektionsspritze kann in horizontaler Richtung um eine Achse bewegt werden. In einer externen Position wird eine Nadel in den Medikamentbehälter eingeführt. Der Antriebsmechanismus der Injektionsspritze (3) bewegt sich gleichzeitig mit der Halterung der Injektionsspritze (233). Diese wird von einem Mechanismus bewegt, der einen Regulierhebel (32) hat. Mit Hilfe dieses Regulierhebels kann die Spritze aus dem Behälter Medizin entnehmen.
  2. Ein automatisierter Spender für Radiopharmazeutikum wie beschrieben in Patentanspruch 1, die Halterung der Injektionsspritze (233) wird durch das Bewegungsmodul der Z-Achse (23) angetrieben, um entlang der senkrechten Z-Achse aufwärts und abwärts bewegt zu werden. Das Bewegungsmodul der Z-Achse (23) wird durch das Bewegungsmodul der Y-Achse (22) in Richtung der Y-Achse auf einer dafür bestimmten Ebene vorwärts und rückwärts bewegt. Das Bewegungsmodul der Y-Achse (22) wird durch das Modul der X-Achse (21) angetrieben und kann in Richtung der X-Achse auf der Ebene vorwärts und rückwärts bewegt werden.
  3. Ein automatisierter Spender für Radiopharmazeutikum wie beschrieben in Patentanspruch 2, der dadurch charakterisiert ist, dass die Halterung der Injektionsspritze (233) mit dem Bewegungsmodul der Z-Achse (23) durch ein Rotationsmodul (24) verbunden ist, welches die Rotation der Halterung der Injektionsspritze (233) um das Bewegungsmodul der Z-Achse (23) antreibt.
  4. Ein automatisierter Spender für Radiopharmazeutikum wie beschrieben in Patentanspruch 1, der dadurch charakterisiert ist, dass sich die Halterung der Injektionsspritze neben dem Bewegungsmechanismus der Halterung für Injektionsspritzen befindet.
  5. Ein automatisierter Spender für Radiopharmazeutikum wie beschrieben in Patentanspruch 4, der dadurch charakterisiert ist, dass sich mindestens ein Zylinder auf dem Boden der Halterung für die Injektionsspritzen (4) befindet, so dass wenn jede Injektionsspritze über der Halterung positioniert ist, sie um jede Spritzennadel gepaart sind.
  6. Ein automatisierter Spender für Radiopharmazeutikum wie beschrieben in Patentanspruch 1, der dadurch charakterisiert ist, dass sich die Injektionsspritze in einer Abschirmung aus Blei (41) befindet, in deren Peripherie sich im mittleren Abschnitt ein Flansch (411) befindet. Die Halterung der Injektionsspritzen (233) hat eine Auskehlung, die mit der Position des Flanschs (411) übereinstimmt. Durch das Verschieben der Auskehlung gegen den Flansch nach vorn und zurück, kann die Halterung befestigt oder gelockert werden.
  7. Ein automatisierter Spender für Radiopharmazeutika wie beschrieben in Patentanspruch 4 oder 5, der dadurch charakterisiert ist, dass sich die Injektionsspritze in einer Bleiabschirmung (41) befindet, in deren Peripherie sich im mittleren Abschnitt ein Flansch befindet. Die Halterung für die Injektionsspritzen hat ein Halterungsschloss, dass mit der Position des Flansches übereinstimmt. Durch die Verschiebung des Halterungsschlosses gegen den Flansch (411) nach vorn und hinten, kann es verschlossen und geöffnet werden.
  8. Ein automatisierter Spender für Radiopharmazeutika wie beschrieben in Patentanspruch 1, der dadurch charakterisiert ist, dass sich der Medizinbehälter in einem Halter (5) mit der Öffnung nach unten befindet.
  9. Ein automatisierter Spender für Radiopharmazeutika wie beschrieben in Patentanspruch 8, der dadurch charakterisiert ist, dass der Medizinbehälter sich in einer Bleidose (51) befindet.
EP20070019673 2007-10-08 2007-10-08 Automatische Abgabevorrichtung für Radiopharmazeutika Not-in-force EP2048081B1 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP20070019673 EP2048081B1 (de) 2007-10-08 2007-10-08 Automatische Abgabevorrichtung für Radiopharmazeutika
DE200760005945 DE602007005945D1 (de) 2007-10-08 2007-10-08 Automatische Abgabevorrichtung für Radiopharmazeutika

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP20070019673 EP2048081B1 (de) 2007-10-08 2007-10-08 Automatische Abgabevorrichtung für Radiopharmazeutika

Publications (2)

Publication Number Publication Date
EP2048081A1 EP2048081A1 (de) 2009-04-15
EP2048081B1 true EP2048081B1 (de) 2010-04-14

Family

ID=39325632

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20070019673 Not-in-force EP2048081B1 (de) 2007-10-08 2007-10-08 Automatische Abgabevorrichtung für Radiopharmazeutika

Country Status (2)

Country Link
EP (1) EP2048081B1 (de)
DE (1) DE602007005945D1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2958625B1 (fr) * 2010-04-07 2012-09-07 Isp System Dispositif de preparation d'une seringue.
CN106511081B (zh) * 2016-11-18 2019-03-05 成都杰仕德科技有限公司 一种针头卡具套件
CN107364822B (zh) * 2017-08-25 2022-09-23 原子高科股份有限公司 一种高精度放射性药液自动分装设备
CN108852832A (zh) * 2018-07-17 2018-11-23 天津屹诺康源医药科技有限公司 一种自动化注射用药品配液机

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003903404A0 (en) * 2003-07-02 2003-07-17 Iphase Technologies Pty. Limited Automated radioactive dose dispenser
US7163031B2 (en) * 2004-06-15 2007-01-16 Mallinckrodt Inc. Automated dispensing system and associated method of use
US7017623B2 (en) * 2004-06-21 2006-03-28 Forhealth Technologies, Inc. Automated use of a vision system to unroll a label to capture and process drug identifying indicia present on the label

Also Published As

Publication number Publication date
EP2048081A1 (de) 2009-04-15
DE602007005945D1 (de) 2010-05-27

Similar Documents

Publication Publication Date Title
US8181677B2 (en) Automated dispenser for radiopharmaceuticals
US8286671B1 (en) Automated syringe filler and loading apparatus
US8807177B2 (en) Automated syringe filler and loading apparatus
EP1981760B1 (de) Maschine mit roboterantrieb zur automatisierten verpackung pharmazeutischer feststoffprodukte
US20110100501A1 (en) Medication mixing device and medication mixing method
EP2048081B1 (de) Automatische Abgabevorrichtung für Radiopharmazeutika
US20100147868A1 (en) Apparatus for releasing drugs
US10959917B2 (en) Medication containers in medication dispensing system
EP1857364A1 (de) Tablettenfüllvorrichtung
US20160343151A1 (en) Medicine photographing apparatus, medicine shape measuring apparatus and medicine dispensing apparatus
CN110368301B (zh) 一种自动配制静脉输液药物的机器人系统
CN109662893B (zh) 药物注射装置及配药设备
US7770358B2 (en) Devices for capping vials useful in system and method for dispensing prescriptions
KR101572005B1 (ko) 캡슐 제조용 분배 장치
US10119983B2 (en) Sample manipulation device
CN107161671B (zh) 一种针剂瓶的自动发放装置
WO2018174710A1 (en) Device for automatically filling product containers with liquids held in one or more source containers
CN213414273U (zh) 一种药学配药装置
JP2006204486A (ja) 薬剤供給装置
US20210316062A1 (en) Modular radio-labeling tracer synthesizer
US20140131534A1 (en) Information reader of injection container
JP5971783B1 (ja) キャップピッキング装置
US20220073222A1 (en) Devices for capping vials useful in system and method for dispensing prescriptions
CN212679619U (zh) 一种可实现胶囊计数和出药的智能药盒
CN114797641B (zh) 配药转运机

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20080911

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR

AX Request for extension of the european patent

Extension state: AL BA HR MK RS

GRAP Despatch of communication of intention to grant a patent

Free format text: ORIGINAL CODE: EPIDOSNIGR1

GRAS Grant fee paid

Free format text: ORIGINAL CODE: EPIDOSNIGR3

AKX Designation fees paid

Designated state(s): CH DE FR LI

GRAA (expected) grant

Free format text: ORIGINAL CODE: 0009210

AK Designated contracting states

Kind code of ref document: B1

Designated state(s): CH DE FR LI

REG Reference to a national code

Ref country code: CH

Ref legal event code: EP

REF Corresponds to:

Ref document number: 602007005945

Country of ref document: DE

Date of ref document: 20100527

Kind code of ref document: P

PLBE No opposition filed within time limit

Free format text: ORIGINAL CODE: 0009261

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT

26N No opposition filed

Effective date: 20110117

REG Reference to a national code

Ref country code: DE

Ref legal event code: R082

Ref document number: 602007005945

Country of ref document: DE

Representative=s name: LERMERRAIBLE GBR PATENT- UND RECHTSANWAELTE, DE

REG Reference to a national code

Ref country code: CH

Ref legal event code: NV

Representative=s name: LERMERRAIBLE GBR PATENT- UND RECHTSANWAELTE, CH

REG Reference to a national code

Ref country code: CH

Ref legal event code: NV

Representative=s name: LERMERRAIBLE GBR PATENT- UND RECHTSANWAELTE, CH

PGFP Annual fee paid to national office [announced via postgrant information from national office to epo]

Ref country code: DE

Payment date: 20131002

Year of fee payment: 7

Ref country code: CH

Payment date: 20131028

Year of fee payment: 7

Ref country code: FR

Payment date: 20131018

Year of fee payment: 7

REG Reference to a national code

Ref country code: DE

Ref legal event code: R119

Ref document number: 602007005945

Country of ref document: DE

REG Reference to a national code

Ref country code: CH

Ref legal event code: PL

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: LI

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20141031

Ref country code: CH

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20141031

Ref country code: DE

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20150501

REG Reference to a national code

Ref country code: FR

Ref legal event code: ST

Effective date: 20150630

PG25 Lapsed in a contracting state [announced via postgrant information from national office to epo]

Ref country code: FR

Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES

Effective date: 20141031