EP2048081B1 - Distributeur automatique pour radio-pharmaceutiques - Google Patents

Distributeur automatique pour radio-pharmaceutiques Download PDF

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Publication number
EP2048081B1
EP2048081B1 EP20070019673 EP07019673A EP2048081B1 EP 2048081 B1 EP2048081 B1 EP 2048081B1 EP 20070019673 EP20070019673 EP 20070019673 EP 07019673 A EP07019673 A EP 07019673A EP 2048081 B1 EP2048081 B1 EP 2048081B1
Authority
EP
European Patent Office
Prior art keywords
syringe
radiopharmaceuticals
moving module
axis moving
automated dispenser
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Not-in-force
Application number
EP20070019673
Other languages
German (de)
English (en)
Other versions
EP2048081A1 (fr
Inventor
Ming-Hsin Lee
Wuu-Jyh Lin
Tain-Shi Zen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Nuclear Energy Research
Original Assignee
Institute of Nuclear Energy Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institute of Nuclear Energy Research filed Critical Institute of Nuclear Energy Research
Priority to EP20070019673 priority Critical patent/EP2048081B1/fr
Priority to DE200760005945 priority patent/DE602007005945D1/de
Publication of EP2048081A1 publication Critical patent/EP2048081A1/fr
Application granted granted Critical
Publication of EP2048081B1 publication Critical patent/EP2048081B1/fr
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like

Definitions

  • the invention is related to an automated dispenser for radiopharmaceuticals. Especially it refers to a situation that hand contact with radiopharmaceuticals is avoided and exposure to radioactive materials is reduced for operators.
  • the main objective for the invention is to provide an automated dispenser for radiopharmaceuticals, so it automatically dispenses high-dose radiopharmaceuticals from bottles into sterile syringes and reduces direct exposure to radioactive environment for operators.
  • Another objective for the invention is to provide an automated dispenser for radiopharmaceuticals, so it uses sterile syringes to dispense radionuclides into bottles for chemical reactions or other uses.
  • Another objective for the invention is to provide an automated dispenser for radiopharmaceuticals, so it is suitable for withdrawing highly toxic and highly contagious pharmaceuticals and demonstrates value of extensive applications.
  • the invention is defined by the features of claim 1.
  • the syringe clamp driven by the Z-axis moving module can ascend or descend along the direction perpendicular to Z-axis.
  • the Z-axis moving module driven by the Y-axis moving module slides back and forth in the direction of Y-axis in a preset horizontal plane.
  • the Y-axis moving module driven by the X-axis moving module slides back and forth in the direction of X-axis in the horizontal plane.
  • the syringe clamp is associated with the Z-axis moving module through a rotation module. Driven by the rotation module, the syringe clamp rotates against the Z-axis moving module.
  • the syringe is located inside a lead shield which periphery has a flange in its middle section.
  • the syringe clamp has a groove corresponding to the flange position. Through the shifting of the groove against the flange back and forth, engagement or disengagement can be achieved.
  • the invention mainly includes: a platform 1, a moving mechanism 2, a syringe driving mechanism 3, a syringe holder 4 and a bottle holder 5.
  • the platform 1 has a supporting plane on top.
  • the moving mechanism 2 is ' composed of an X-axis moving module 21, a Y-axis moving module 22, a Z-axis moving module 23 and a rotation module 24.
  • TheX-axis moving module 21 is located on the supporting plane of the platform 1.
  • a power source 211 (such as a step motor) drives a shifting platform 212 to move along a preset straight track (assuming it is X-axis).
  • the Y-axis moving module 22 is located on the shifting platform 212 and uses a power source 221 (such as a step motor) to drive a shifting platform 222 to move along a straight track perpendicular to X-axis (assuming it is Y-axis).
  • the rotation module 24 is located on the shifting platform 222 and uses a power source 241 to drive a rotation base 242 to turn around the axis parallel to Y-axis.
  • the Z-axis moving module 23 is located on the rotation base 242 and uses a power source 231 (such as a step motor) to drive a shifting base 232 to move along a straight track (assuming it is Z-axis) perpendicular to X-axis and Y-axis.
  • the shifting base 232 has a syringe clamp 233.
  • the syringe clamp 233 has a clamping slot 234 with an opening.
  • the syringe driving mechanism 3 is associated with the shifting base 232, and uses a power source 31 (such as a step motor) to drive a driving rod 32 to move along a straight track parallel to Z-axis, and makes the driving rod 32 to connect with a moving device 33 which bottom has a clamping slot 34 with an opening.
  • the syringe holder 4 is located at one side of the moving mechanism 2 for accommodating a plural number of syringes 42.
  • the syringes 42 are located inside a lead shield 41.
  • the lead shield 41 has a flange 411 in the middle section of its periphery.
  • a flange 411 At the bottom of the syringe holder 4 there are a plural number of syringe cylinders corresponding to the syringe 42 position. So when the syringe 42 is positioned at the syringe holder 4, each cylinder is placed outside the syringe.
  • the bottle holder 5 is located beside the moving mechanism 2 and the syringe holder 4 and mainly used to hold bottles for radiopharmaceuticals. The bottles are placed and fixed in a designated lead box 51 and have their mouth down for the convenience of withdrawing drug.
  • the moving mechanism 2 through digital system control makes X-axis moving module 21, Y-axis moving module 22 and Z-axis moving module 23 to shift in a proper distance and makes the clamping slot 234 for the syringe clamp 233 to put on the flange 411 of the lead shield 41, while the clamping slot 34 of the syringe driving mechanism 3 can be put on the drug-withdrawing rod of the syringe 42. Then the shifting base 232 of the Z-axis moving module 23 rises to make the lead shield 41 and the syringe 42 to detach from the syringe holder 4.
  • the X-axis moving module 21 and the Y-axis moving module 22 drive the syringe 42 to shift under the lead box 51 for the bottle holder 5.
  • the rotation module 24 drives the syringe 42 to rotate in 180 degrees and make the needle of the syringe 42 upward.
  • the shifting base 232 of the Z-axis moving module 23 rises again to make the syringe 42 needle to insert into the drug bottle.
  • the driving rod 32 for the syringe driving mechanism 3 drives the moving device 33 and the clamping slot 34 drives the drug-withdrawing rod of the syringe 42 to withdraw radiopharmaceuticals from the bottle.
  • the shifting base 232 of the Z-axis moving module 23 descends to make the syringe 42 needle to detach from the drug bottle. Then X-axis moving module 21 and Y-axis moving module 22 drive the syringe 42 to shift above the syringe holder 4.
  • the rotation module 24 drives the syringe 42 to rotate in 180 degrees and makes the syringe 42 needles downward.
  • the shifting base 232 of the Z-axis moving module 23 descends to position the syringe 42 into the syringe holder 4 and the needle extends into the cylinder to complete the drug dispensing process.
  • the automated dispenser for radiopharmaceuticals in the invention can prevent operators from contacting radiopharmaceuticals and reduce exposure to radiation.
  • the invention is an innovative and advanced achievement. The above content is only an explanation for a preferred embodiment for the invention.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Claims (9)

  1. Un distributeur automatisé pour des produits radio-pharmaceutiques, comprenant:
    une plateforme (1) ayant un plateau de support installé au-dessus;
    une bouteille à médicaments située sur un côté de la plateforme;
    un mécanisme de déplacement (2), caractérisé en ce que ce mécanisme de déplacement (2) est au moins composé d'un module de déplacement sur l'axe-X (21), un module de déplacement sur l'axe-Y (22) et un module de déplacement sur l'axe-Z (23), équipés sur la plateforme pour diriger un étau à seringue (233) pour tenir une seringue (42), la déplacer en avant et en arrière dans un espace tridimensionnel et la tourner selon un axe horizontal afin que la seringue puisse bouger d'une position externe vers l'endroit où une aiguille est insérée dans la bouteille ; et
    un mécanisme de direction pour seringue (3), adapté pour bouger simultanément avec l'étau à seringue (233), dirigé par le mécanisme de déplacement et ayant une tige de direction (32) sur laquelle il est possible de faire retirer le médicament par la seringue.
  2. Un distributeur automatisé pour des produits radio-pharmaceutiques comme décrit dans la Revendication 1, l'étau à seringue (233) est dirigé par le module de déplacement sur l'axe-Z (23) pour monter ou descendre le long de l'axe-Z perpendiculaire; le module de déplacement sur l'axe-Z (23) est dirigé par le module de déplacement sur l'axe-Y (22) pour faire coulisser en avant et en arrière dans la direction de l'axe-Y dans un plan prédéfini et le module de déplacement sur l'axe-Y (22) est dirigé par le module de déplacement sur l'axe-X (21) pour faire coulisser en avant et en arrière dans la direction de l'axe-X dans le plan.
  3. Un distributeur automatisé pour des produits radio-pharmaceutiques comme décrit dans la Revendication 2, caractérisé en ce que l'étau à seringue (233) est associé avec le module de déplacement sur l'axe-Z (23) via un module de rotation (24), qui dirige la rotation de l'étau à seringue (233) autour du module de déplacement sur l'axe-Z (23).
  4. Un distributeur automatisé pour des produits radio-pharmaceutiques comme décrit dans la Revendication 1, caractérisé en ce qu'un support de seringue se trouve en-dessous du mécanisme de déplacement pour que la plateforme puisse soutenir des seringues.
  5. Un distributeur automatisé pour des produits radio-pharmaceutiques comme décrit dans la Revendication 4, caractérisé en ce qu'au moins un cylindre de seringue se trouve au bas du support de seringue (4), afin que quand chaque seringue est positionnée au-dessus du support, elle peut être couplée autour de chaque aiguille.
  6. Un distributeur automatisé pour des produits radio-pharmaceutiques comme décrit dans la Revendication 1, caractérisé en ce que la seringue est située dans un bouclier en plomb (41), dont la périphérie a un boudin (411) dans sa section centrale; l'étau à seringue (233) a une fente correspondant à la position du boudin (411) et grâce au déplacement de la fente contre l'avant ou l'arrière du boudin, l'engagement ou le désengagement peut être atteint.
  7. Un distributeur automatisé pour des produits radio-pharmaceutiques comme décrit dans la Revendication 4 ou 5, caractérisé en ce que la seringue est située dans un bouclier en plomb (41), dont la périphérie a un boudin dans sa section centrale; l'étau à seringue a un socle d'étau correspondant à la position du boudin et grâce au déplacement du socle d'étau contre l'avant et l'arrière du boudin (411), l'engagement ou le désengagement peut être atteint.
  8. Un distributeur automatisé pour des produits radio-pharmaceutiques comme décrit dans la Revendication 1, caractérisé en ce que la bouteille de médicaments se trouve sur le support de bouteille (5) avec le col vers le bas.
  9. Un distributeur automatisé pour des produits radio-pharmaceutiques comme décrit dans la Revendication 8, caractérisé en ce que la bouteille est située dans une boîte en plomb (51).
EP20070019673 2007-10-08 2007-10-08 Distributeur automatique pour radio-pharmaceutiques Not-in-force EP2048081B1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP20070019673 EP2048081B1 (fr) 2007-10-08 2007-10-08 Distributeur automatique pour radio-pharmaceutiques
DE200760005945 DE602007005945D1 (de) 2007-10-08 2007-10-08 Automatische Abgabevorrichtung für Radiopharmazeutika

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP20070019673 EP2048081B1 (fr) 2007-10-08 2007-10-08 Distributeur automatique pour radio-pharmaceutiques

Publications (2)

Publication Number Publication Date
EP2048081A1 EP2048081A1 (fr) 2009-04-15
EP2048081B1 true EP2048081B1 (fr) 2010-04-14

Family

ID=39325632

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20070019673 Not-in-force EP2048081B1 (fr) 2007-10-08 2007-10-08 Distributeur automatique pour radio-pharmaceutiques

Country Status (2)

Country Link
EP (1) EP2048081B1 (fr)
DE (1) DE602007005945D1 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2958625B1 (fr) * 2010-04-07 2012-09-07 Isp System Dispositif de preparation d'une seringue.
CN106511081B (zh) * 2016-11-18 2019-03-05 成都杰仕德科技有限公司 一种针头卡具套件
CN107364822B (zh) * 2017-08-25 2022-09-23 原子高科股份有限公司 一种高精度放射性药液自动分装设备
CN108852832A (zh) * 2018-07-17 2018-11-23 天津屹诺康源医药科技有限公司 一种自动化注射用药品配液机

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003903404A0 (en) * 2003-07-02 2003-07-17 Iphase Technologies Pty. Limited Automated radioactive dose dispenser
US7163031B2 (en) * 2004-06-15 2007-01-16 Mallinckrodt Inc. Automated dispensing system and associated method of use
US7017623B2 (en) * 2004-06-21 2006-03-28 Forhealth Technologies, Inc. Automated use of a vision system to unroll a label to capture and process drug identifying indicia present on the label

Also Published As

Publication number Publication date
DE602007005945D1 (de) 2010-05-27
EP2048081A1 (fr) 2009-04-15

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