EP2048081A1 - Automatische Abgabevorrichtung für Radiopharmazeutika - Google Patents

Automatische Abgabevorrichtung für Radiopharmazeutika Download PDF

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Publication number
EP2048081A1
EP2048081A1 EP07019673A EP07019673A EP2048081A1 EP 2048081 A1 EP2048081 A1 EP 2048081A1 EP 07019673 A EP07019673 A EP 07019673A EP 07019673 A EP07019673 A EP 07019673A EP 2048081 A1 EP2048081 A1 EP 2048081A1
Authority
EP
European Patent Office
Prior art keywords
syringe
radiopharmaceuticals
moving module
axis moving
automated dispenser
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP07019673A
Other languages
English (en)
French (fr)
Other versions
EP2048081B1 (de
Inventor
Ming-Hsin Lee
Wuu-Jyh Lin
Tain-Shi Zen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institute of Nuclear Energy Research
Original Assignee
Institute of Nuclear Energy Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Institute of Nuclear Energy Research filed Critical Institute of Nuclear Energy Research
Priority to DE200760005945 priority Critical patent/DE602007005945D1/de
Priority to EP20070019673 priority patent/EP2048081B1/de
Publication of EP2048081A1 publication Critical patent/EP2048081A1/de
Application granted granted Critical
Publication of EP2048081B1 publication Critical patent/EP2048081B1/de
Not-in-force legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65BMACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/003Filling medical containers such as ampoules, vials, syringes or the like

Definitions

  • the invention is related to an automated dispenser for radiopharmaceuticals. Especially it refers to a situation that hand contact with radiopharmaceuticals is avoided and exposure to radioactive materials is reduced for operators.
  • the main objective for the invention is to provide an automated dispenser for radiopharmaceuticals, so it automatically dispenses high-dose radiopharmaceuticals from bottles into sterile syringes and reduces direct exposure to radioactive environment for operators.
  • Another objective for the invention is to provide an automated dispenser for radiopharmaceuticals, so it uses sterile syringes to dispense radionuclides into bottles for chemical reactions or other uses.
  • Another objective for the invention is to provide an automated dispenser for radiopharmaceuticals, so it is suitable for withdrawing highly toxic and highly contagious pharmaceuticals and demonstrates value of extensive applications.
  • the technical approaches include: one platform with at least one supporting plane at top; one drug bottle at one side of the platform; one moving mechanism located on the supporting plane to drive a syringe clamp to hold a syringe and move it in space repeatedly, and rotate around an axis in the parallel direction to make the syringe to move from outside to the position for a needle to insert; a syringe driving mechanism to move simultaneously with the syringe clamp driven by the moving mechanism and to have a driving rod on it to drive the syringe cylinder for withdrawing drug.
  • the moving mechanism is at least composed of an X-axis moving module, a Y-axis moving module and a Z-axis moving module. So the syringe clamp driven by the Z-axis moving module can ascend or descend along the direction perpendicular to Z-axis.
  • the Z-axis moving module driven by the Y-axis moving module slides back and forth in the direction of Y-axis in a preset horizontal plane.
  • the Y-axis moving module driven by the X-axis moving module slides back and forth in the direction of X-axis in the horizontal plane.
  • the syringe clamp is associated with the Z-axis moving module through a rotation module. Driven by the rotation module, the syringe clamp rotates against the Z-axis moving module.
  • the syringe is located inside a lead shield which periphery has a flange in its middle section.
  • the syringe clamp has a groove corresponding to the flange position. Through the shifting of the groove against the flange back and forth, engagement or disengagement can be achieved.
  • the invention mainly includes: a platform 1, a moving mechanism 2, a syringe driving mechanism 3, a syringe holder 4 and a bottle holder 5.
  • the platform 1 has a supporting plane on top.
  • the moving mechanism 2 is composed of an X-axis moving module 21, a Y-axis moving module 22, a Z-axis moving module 23 and a rotation module 24.
  • the X-axis moving module 21 is located on the supporting plane of the platform 1.
  • a power source 211 (such as a step motor) drives a shifting platform 212 to move along a preset straight track (assuming it is X-axis).
  • the Y-axis moving module 22 is located on the shifting platform 212 and uses a power source 221 (such as a step motor) to drive a shifting platform 222 to move along a straight track perpendicular to X-axis (assuming it is Y-axis).
  • the rotation module 24 is located on the shifting platform 222 and uses a power source 241 to drive a rotation base 242 to turn around the axis parallel to Y-axis.
  • the Z-axis moving module 23 is located on the rotation base 242 and uses a power source 231 (such as a step motor) to drive a shifting base 232 to move along a straight track (assuming it is Z-axis) perpendicular to X-axis and Y-axis.
  • the shifting base 232 has a syringe clamp 233.
  • the syringe clamp 233 has a clamping slot 234 with an opening.
  • the syringe driving mechanism 3 is associated with the shifting base 232, and uses a power source 31 (such as a step motor) to drive a driving rod 32 to move along a straight track parallel to Z-axis, and makes the driving rod 32 to connect with a moving device 33 which bottom has a clamping slot 34 with an opening.
  • the syringe holder 4 is located at one side of the moving mechanism 2 for accommodating a plural number of syringes 42.
  • the syringes 42 are located inside a lead shield 41.
  • the lead shield 41 has a flange 411 in the middle section of its periphery.
  • a flange 411 At the bottom of the syringe holder 4 there are a plural number of syringe cylinders corresponding to the syringe 42 position. So when the syringe 42 is positioned at the syringe holder 4, each cylinder is placed outside the syringe.
  • the bottle holder 5 is located beside the moving mechanism 2 and the syringe holder 4 and mainly used to hold bottles for radiopharmaceuticals. The bottles are placed and fixed in a designated lead box 51 and have their mouth down for the convenience of withdrawing drug.
  • the moving mechanism 2 through digital system control makes X-axis moving module 21, Y-axis moving module 22 and Z-axis moving module 23 to shift in a proper distance and makes the clamping slot 234 for the syringe clamp 233 to put on the flange 411 of the lead shield 41, while the clamping slot 34 of the syringe driving mechanism 3 can be put on the drug-withdrawing rod of the syringe 42. Then the shifting base 232 of the Z-axis moving module 23 rises to make the lead shield 41 and the syringe 42 to detach from the syringe holder 4.
  • the X-axis moving module 21 and the axis moving module 22 drive the syringe 42 to shift under the lead box 51 for the bottle holder 5.
  • the rotation module 24 drives the syringe 42 to rotate in 180 degrees and make the needle of the syringe 42 upward.
  • the shifting base 232 of the Z-axis moving module 23 rises again to make the syringe 42 needle to insert into the drug bottle.
  • the driving rod 32 for the syringe driving mechanism 3 drives the moving device 33 and the clamping slot 34 drives the drug-withdrawing rod of the syringe 42 to withdraw radiopharmaceuticals from the bottle.
  • the shifting base 232 of the Z-axis moving module 23 descends to make the syringe 42 needle to detach from the drug bottle. Then X-axis moving module 21 and Y-axis moving module 22 drive the syringe 42 to shift above the syringe holder 4.
  • the rotation module 24 drives the syringe 42 to rotate in 180 degrees and makes the syringe 42 needles downward.
  • the shifting base 232 of the Z-axis moving module 23 descends to position the syringe 42 into the syringe holder 4 and the needle extends into the cylinder to complete the drug dispensing process.
  • the automated dispenser for radiopharmaceuticals in the invention can prevent operators from contacting radiopharmaceuticals and reduce exposure to radiation.
  • the invention is an innovative and advanced achievement.
  • the patent application is thus submitted. The above content is only an explanation for a preferred embodiment for the invention. Those changes, modification, alteration or equivalent replacements based on the technical approach and extension of the scope of the invention shall fall into the claims of the patent application.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
EP20070019673 2007-10-08 2007-10-08 Automatische Abgabevorrichtung für Radiopharmazeutika Not-in-force EP2048081B1 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE200760005945 DE602007005945D1 (de) 2007-10-08 2007-10-08 Automatische Abgabevorrichtung für Radiopharmazeutika
EP20070019673 EP2048081B1 (de) 2007-10-08 2007-10-08 Automatische Abgabevorrichtung für Radiopharmazeutika

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP20070019673 EP2048081B1 (de) 2007-10-08 2007-10-08 Automatische Abgabevorrichtung für Radiopharmazeutika

Publications (2)

Publication Number Publication Date
EP2048081A1 true EP2048081A1 (de) 2009-04-15
EP2048081B1 EP2048081B1 (de) 2010-04-14

Family

ID=39325632

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20070019673 Not-in-force EP2048081B1 (de) 2007-10-08 2007-10-08 Automatische Abgabevorrichtung für Radiopharmazeutika

Country Status (2)

Country Link
EP (1) EP2048081B1 (de)
DE (1) DE602007005945D1 (de)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2958625A1 (fr) * 2010-04-07 2011-10-14 Isp System Dispositif de preparation d'une seringue.
CN106511081A (zh) * 2016-11-18 2017-03-22 成都杰仕德科技有限公司 一种针头卡具套件
CN107364822A (zh) * 2017-08-25 2017-11-21 原子高科股份有限公司 一种高精度放射性药液自动分装设备
CN108852832A (zh) * 2018-07-17 2018-11-23 天津屹诺康源医药科技有限公司 一种自动化注射用药品配液机

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050278066A1 (en) * 2004-06-15 2005-12-15 Kevin Graves Automated dispensing system and associated method of use
US20050279419A1 (en) * 2004-06-21 2005-12-22 Dennis Tribble Automated use of a vision system to unroll a label to capture and process drug identifying indicia present on the label
US20060151048A1 (en) * 2003-07-02 2006-07-13 Henri-Jacques Tochon-Danguy Process and device for the dose dispensing of a radioactive solution

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060151048A1 (en) * 2003-07-02 2006-07-13 Henri-Jacques Tochon-Danguy Process and device for the dose dispensing of a radioactive solution
US20050278066A1 (en) * 2004-06-15 2005-12-15 Kevin Graves Automated dispensing system and associated method of use
US20050279419A1 (en) * 2004-06-21 2005-12-22 Dennis Tribble Automated use of a vision system to unroll a label to capture and process drug identifying indicia present on the label

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2958625A1 (fr) * 2010-04-07 2011-10-14 Isp System Dispositif de preparation d'une seringue.
WO2011124780A3 (fr) * 2010-04-07 2012-07-12 Isp System Dispositif de preparation d'une seringue
CN106511081A (zh) * 2016-11-18 2017-03-22 成都杰仕德科技有限公司 一种针头卡具套件
CN107364822A (zh) * 2017-08-25 2017-11-21 原子高科股份有限公司 一种高精度放射性药液自动分装设备
CN107364822B (zh) * 2017-08-25 2022-09-23 原子高科股份有限公司 一种高精度放射性药液自动分装设备
CN108852832A (zh) * 2018-07-17 2018-11-23 天津屹诺康源医药科技有限公司 一种自动化注射用药品配液机

Also Published As

Publication number Publication date
DE602007005945D1 (de) 2010-05-27
EP2048081B1 (de) 2010-04-14

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