EP2037796A2 - Capteur d'analyte et dispositif de perfusion intégrés, et procédés connexes - Google Patents

Capteur d'analyte et dispositif de perfusion intégrés, et procédés connexes

Info

Publication number
EP2037796A2
EP2037796A2 EP20070799109 EP07799109A EP2037796A2 EP 2037796 A2 EP2037796 A2 EP 2037796A2 EP 20070799109 EP20070799109 EP 20070799109 EP 07799109 A EP07799109 A EP 07799109A EP 2037796 A2 EP2037796 A2 EP 2037796A2
Authority
EP
European Patent Office
Prior art keywords
cannula
patient
sensor
analyte
time period
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP20070799109
Other languages
German (de)
English (en)
Inventor
R. Curtis Jennewine
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Diabetes Care Inc
Original Assignee
Abbott Diabetes Care Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Diabetes Care Inc filed Critical Abbott Diabetes Care Inc
Publication of EP2037796A2 publication Critical patent/EP2037796A2/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14503—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
    • A61M2005/14252—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type with needle insertion means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • A61M2005/1726—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure the body parameters being measured at, or proximate to, the infusion site
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3546—Range
    • A61M2205/3569—Range sublocal, e.g. between console and disposable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/35—Communication
    • A61M2205/3576—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver
    • A61M2205/3592—Communication with non implanted data transmission devices, e.g. using external transmitter or receiver using telemetric means, e.g. radio or optical transmission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/005—Parameter used as control input for the apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/20—Blood composition characteristics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/20—Blood composition characteristics
    • A61M2230/201—Glucose concentration

Definitions

  • Diabetic patients periodically administer insulin to sustain their physiological conditions. Typically, these patients administer doses of either fast acting or slow acting insulin using needle type syringes, for example, prior to meals, and/or at a suitable time during the course of each day contemporaneously with the blood glucose level testing using fmgerstick testing, for example. If insulin is not suitably administered, the diabetic patients risk serious if not fatal damage to the body.
  • the patient inserts a cannula which is connected to as infusion tubing attached to an external pump, and insulin is administered based on preprogrammed basal profiles.
  • the external infusion devices include computational capability to determined suitable bolus doses such as carbohydrate bolus and correction bolus, for example, to be administered in conjunction with the infusion device executing the patient's basal profile.
  • the infusion site where the cannula is positioned under the skin layer of the patient experiences results in tissue or skin trauma.
  • the infusion site is typically changed with each change of the infusion set, for example, every three days or so.
  • the infusion site may also be prone to infection and other adverse consequences as a result of the transcutaneous placement of the cannula for insulin delivery.
  • current development in analyte monitoring typically uses a transcutaneously positioned biosensor which is in fluid contact with the patient's analyte to monitor, for example, analyte levels of the patient.
  • a patient using an infusion device and also using an analyte monitoring system must periodically replace the cannula for the infusion system, and the biosensor for the analyte monitoring system, and which may be at different times during the course of infusion therapy and analyte monitoring.
  • an integrated analyte monitoring system and on- body patch pump with multiple cannulas and a sensor combination there are provided methods and system for deploying multiple infusion cannulas for use with an extended analyte sensor (for example, a 7 day sensor).
  • an extended analyte sensor for example, a 7 day sensor
  • FIG. 1 is a block diagram illustrating an overall therapy management system for practicing one embodiment of the present invention
  • FIGS 2A and 2B illustrate multiple cannulas integrated with an extended use analyte sensor in a patch pump configuration in accordance with one embodiment of the present invention
  • FIG. 3 illustrates a combined patch pump system integrated with the second cannula during the second part of the sensor life in accordance with one embodiment of the present invention
  • FIGS. 4A and 4B illustrate multiple cannulas integrated with an extended use analyte sensor in a patch pump configuration in accordance with another embodiment of the present invention
  • FIGS. 5A and 5B illustrate alternate embodiments showing infusion fluid provision in accordance with one embodiment of the present invention.
  • FIG. 1 is a block diagram illustrating an overall therapy management system for practicing one embodiment of the present invention.
  • the therapy management system 100 includes a controller 110 configured for bidirectional wireless communication with an on-body patch pump 120.
  • the controller 110 is configured to control the operation of the patch pump 120 based on, for example, preprogrammed delivery profiles for infusion of therapeutic agent, such as, including but not limited to insulin.
  • the controller 110 includes one or more user input unit, and one or more user output unit for user directed programming of the patch pump 120 using the controller 110, and further, to provide visual, auditory, and/or vibratory output signals for communicating with the user.
  • the patch pump 120 in one embodiment is provided with an adhesive layer 123 which is configured to adhere on the skin of a patient during use.
  • the patch pump 120 includes a cannula 121 for establishing a fluid path between a reservoir (not shown) containing the therapeutic fluid for delivery and the infusion site of the patient. Also shown in the Figure is a sensor 122. As shown in -A-
  • FIG. 1 a portion of the cannula 121 and the sensor 122 are positioned under the skin of the patient, and thus, at least a portion of each are configured to extend from the lower surface of the patch pump 120 through the skin layer of the patient.
  • the senor 122 includes an analyte sensor which is configured to establish fluid contact with the interstitial fluid of the patient so as to detect the analyte level, such as glucose level, of the patient. That is, the transmitter unit 124 may be configured to receive one or more signals from the analyte sensor 122 corresponding to the detected analyte levels of the patient, and to transmit the information corresponding to the detected analyte levels to the receiver/monitor 130 and/or the controller 120.
  • the analyte sensor which is configured to establish fluid contact with the interstitial fluid of the patient so as to detect the analyte level, such as glucose level, of the patient. That is, the transmitter unit 124 may be configured to receive one or more signals from the analyte sensor 122 corresponding to the detected analyte levels of the patient, and to transmit the information corresponding to the detected analyte levels to the receiver/monitor 130 and/or the controller 120.
  • the transmitter unit 124 may be configured to transmit data associated with the detected analyte levels periodically, and/or intermittently and repeatedly to one or more other devices such as controller 110 and/or the receiver/monitor 130 for further data processing and analysis.
  • the one or more of the controller 110 and the receiver/monitor 130 may include a strip port configured to receive a test strip for capillary blood glucose testing.
  • the glucose level measured using the test strip may in addition, be configured to provide periodic calibration of the sensor 122 to assure and improve the accuracy of the analyte levels detected by the analyte sensor 122.
  • the analyte sensor 122 may include, but not limited to short term subcutaneous analyte sensors or transdermal analyte sensors, for example, which are configured to detect analyte levels of a patient over a predetermined time period, and after which, a replacement of the sensors is necessary.
  • Additional analytes that may be monitored, determined or detected the analyte monitoring system 110 include, for example, acetyl choline, amylase, amyln, bilirubin, cholesterol, chorionic gonadotropin, creatine kinase (e.g., CK-MB), creatine, DNA, fructosamine, glucose, glutamine, growth hormones, hormones, ketones, lactate, measures for oxidative stress (such as 8-iso PGF2gamma), peroxide, prostate-specific antigen, prothrombin, RNA, thyroid stimulating hormone, and troponin.
  • oxidative stress such as 8-iso PGF2gamma
  • both the cannula 121 and the sensor 122 may be transcutaneously positioned under the skin layer of the patient using an insertion device (not shown) that includes a sharp penetrating member such as an insertion needle.
  • the sensor 122 and the cannula 121 may be configured with sufficient rigidity to pierce through the skin of the patient without additional piercing guides such as the sharp penetrating member of the insertion device.
  • the transmitter unit 124 in one embodiment is configured to maintain electrical communication with the sensor 122 such that the detected analyte levels from the sensor 122 may be transmitted by the transmitter unit 124 to the controller 110.
  • the controller 110 may be configured to communicate with the transmitter unit 124 so as to provide analyte monitoring functions.
  • a receiver/monitor unit 130 which is configured to communicate with the transmitter unit 124 to receive the detected analyte levels for further processing.
  • the patch pump 120 control functions and the analyte monitoring functions may be incorporated in the controller 110 such that the patient need only carry one device.
  • the receiver/monitor unit 130 in one embodiment may include for example, a desktop computer terminal, a data communication enabled kiosk, a laptop computer, a handheld computing device such as a personal digital assistant (PDAs), or a data communication enabled mobile telephone. Similar to the controller 110 discussed above, the receiver/monitor unit 130 may include a user interface unit which may include a display unit and/or an audio output unit such as, for example, a speaker, and/or any other suitable user interface mechanism for displaying or informing the user of such devices.
  • a user interface unit which may include a display unit and/or an audio output unit such as, for example, a speaker, and/or any other suitable user interface mechanism for displaying or informing the user of such devices.
  • both the controller 110 and the receive/monitor 130 are configured with a substantially compact housing and sized such that the devices may be easily and comfortably be held in the patient's hand, worn on the patient's clothing, or placed inside a pocket of the patient's clothing without much discomfort.
  • the patch pump 120 may be configured with a substantially compact housing and sized such that the patient experiences minimal discomfort during the seven or more days of continuous on-body use.
  • FIGS 2A and 2B illustrate multiple cannulas integrated with an extended use analyte sensor in a patch pump configuration in accordance with one embodiment of the present invention.
  • patch pump 210 in one embodiment includes a controller 230 (e.g., a microprocessor) operatively coupled to an infusion management unit (IMU) 220 which includes, among others, a reservoir (not shown) for retaining therapeutic agent such as insulin for delivery to the patient.
  • IMU infusion management unit
  • the infusion management unit (IMU) 220 may include other components such as power supply (e.g., battery), and/or fluid path management section which, in one embodiment, may be configured to connect the a cannula 240 to the reservoir for therapeutic agent delivery to the patient, and further, to control the placement or positioning of the first cannula 240, and subsequent retraction of the first cannula 240 upon reaching the end of its useful life cycle.
  • power supply e.g., battery
  • fluid path management section which, in one embodiment, may be configured to connect the a cannula 240 to the reservoir for therapeutic agent delivery to the patient, and further, to control the placement or positioning of the first cannula 240, and subsequent retraction of the first cannula 240 upon reaching the end of its useful life cycle.
  • the infusion management unit (IMU) 220 may include a transceiver (not shown) for bi-directional communication with one or more of the controller 110 and the receiver/monitor 130.
  • the transceiver may be configured to receive infusion related commands or instruction from the one or more of the controller 110 and the receiver/monitor 130, and further, to transmit one or more information associated with the fluid flow information or the operating condition of the patch pump 120.
  • the infusion management unit (IMU) 220 in one embodiment is connected to a port 270 provided substantially at the housing of the patch pump 210.
  • the infusion management unit (IMU) 220 is configured to maintain a fluid path to the port 270.
  • the port 270 may include a self-sealing septum which is substantially configured to be water proof.
  • the port 270 may include a uni- directional connector for mating with an infusion tubing 280 to establish fluid path between the infusion management unit 220 and a second cannula 290 as shown in FIG. 2B.
  • the infusion management unit (IMU) 270 may be configured to manage the infusion of the therapeutic agent such that the first cannula 240 transcutaneously positioned at the first infusion site is used for a predetermined time period (for example, approximately three to four days), and thereafter, retract the first cannula 240 from the first infusion site (and retained within the housing of the patch pump 210), while connecting the infusion tubing 280 to the port 270 establishes a fluid path to the second cannula 290 to infuse the therapeutic agent to the patient in a continuous manner.
  • a predetermined time period for example, approximately three to four days
  • a sensor 250 such as, for example, an analyte sensor, at least a portion of which is transcutaneously positioned under the skin layer of the patient.
  • the sensor 250 is operative Iy coupled to a transmitter unit 260 which is configured to communicate with, for example, the controller 110 (FIG. 1) and/or the receiver/monitor 130 (FIG. 1).
  • the sensor 250 is configured for approximately seven or more days of use. As such, it is desirable to change the infusion site of the therapeutic agent delivery at approximately mid point in the usage life of the sensor 250 (i.e., after approximately three or four days of use).
  • the first cannula 240 is configured for transcutaneous delivery of the therapeutic agent at the first infusion site for the initial time period of approximately three or four days. Thereafter, the first cannula 240 is retracted from the infusion site under the control and operation of one or more of the controller 230 and the infusion management unit 220, and in one embodiment, wholly retained within the housing of the patch pump
  • the infusion tubing 280 connected to the second cannula 290 is coupled to the port 270 to establish fluid contact with the infusion management unit (IMU) 220. This is shown in FIG. 3.
  • IMU infusion management unit
  • the tubing 280 may be either pre -primed or is primed by the controller 230 and/or the infusion management unit (IMU) 220.
  • the tip of the tubing 280 for mating or connection to the port 270 may be configured to engage with the port 270 so as to establish a water tight seal.
  • the second cannula 290 is transcutaneously positioned at the second infusion site (which is different from the first infusion site on the patient) for delivery of the therapeutic agent.
  • the insertion process of the second cannula 290 may be automated using an insertion device such as an insertion gun that is configured to couple to the second cannula 290 (for example, the insertion needle coupled to the second cannula 290) and which includes a spring bias driven insertion mechanism.
  • the insertion process may be primarily manual whereby the patient manually inserts the second cannula at the desired second infusion site.
  • the patch pump 210 may be configured for operation for approximately seven or more days for therapeutic agent delivery, and further, integrated with a continuous monitoring system wherein the sensor 250 is configured to continuously monitor the analyte level of the patient during the seven or more days of use without interruption.
  • the monitored analyte levels as well as the therapeutic agent delivery associated information are communicated to the controller 110 (FIG. 1) and/or the receiver/monitor 130 by, for example, the transmitter unit 260.
  • the controller 110 FIG. 1
  • the receiver/monitor 130 by, for example, the transmitter unit 260.
  • potential for skin irritation and/or damage to patient's tissue at the infusion site by the cannula and/or the therapeutic agent may be minimized.
  • FIGS. 4A and 4B illustrate multiple cannulas integrated with an extended use analyte sensor in a patch pump configuration in accordance with another embodiment of the present invention.
  • patch pump 410 in one embodiment includes a first cannula 440 and a second cannula 470 disposed therein. Also shown in the Figure is the infusion management unit (IMU) 420 which is operatively coupled to the first cannula 440 and the second cannula 470.
  • IMU infusion management unit
  • a controller 430 is operatively coupled to the infusion management unit (IMU) 420 and to a transmitter unit 460. Similar to the controller 230 discussed above in conjunction with FIGS. 2A-2B and 3, the controller 430 in one embodiment is configured to control the operating functions of the infusion management unit (IMU) 420 and the transmitter unit 450, for managing therapeutic agent delivery via the respective first and second cannulas 440, 470, and for managing the data transmission of the transmitter unit 460 that is configured to receive one or more analyte associated signals from a sensor 450. Referring back to FIG. 4A, in one embodiment, the initial transcutaneous placement of the sensor 450 and the first cannula 440 is performed substantially simultaneously (or near simultaneously).
  • the first cannula 450 is configured to be withdrawn from the infusion site, while the second cannula (pre-deployed) is transcutaneously inserted into the patient.
  • An adhesive patch 411 is configured to substantially fixedly retain the patch pump 410 on the adhered portion of the patient's skin during the entire duration of the patch pump 410 usage (for example, seven or more days).
  • the first cannula 440 in one embodiment is withdrawn from the first infusion site, and substantially and entirely retained within the housing of the patch pump 410, while the second cannula 470 is transcutaneously positioned at the second infusion site.
  • the infusion management unit (IMU) 420 in one embodiment includes a reservoir containing the therapeutic agent, and to establish the appropriate fluid communication with the first and second cannulas 440, 470.
  • the controller 430 may be configured to control the operation of the infusion management unit (IMU) 420 so as to provide continuous and uninterrupted delivery of the therapeutic agent to the patient during the duration in which the sensor 450 is detecting the analyte levels of the patient.
  • controller 110 (FIG. 1) and/or the receiver/monitor 130 may be configured to substantially control the programming of the patch pump
  • IMU infusion management unit
  • controller 430 of the patch pump 410 such that the operation of the infusion management unit (IMU) 420 and the controller 430 of the patch pump 410 are configured to receive the commands or instructions from the controller 110 and/or the receiver/monitor 130 to execute the appropriate functions.
  • functions include, but are not limited to the delivery of programmed basal profiles, delivery of carbohydrate bolus dosage, implementing a temporary basal modification, insertion and/or retraction of the first cannula 440, and the insertion and/or retraction of the second cannula 470.
  • a mounting base (not shown) may be provided which includes the adhesive layer 411 there under, and which may be configured to guide the insertion of the first cannula 440 and the sensor 450.
  • the first cannula 440 and the sensor 450 may be transcutaneous Iy positioned prior to the placement or positioning of the patch pump 410 on the patient's skin. In this configuration, the first cannula 440 and the sensor 450 may not be initially retained within the housing of the patch pump 410. Rather, an insertion device may be used to separately insert the first cannula 440 and the sensor 450. Thereafter, the patch pump
  • FIGS. 5A and 5B illustrate alternate embodiments showing infusion fluid provision in accordance with one embodiment of the present invention. Referring to FIG. 5A, it can be seen that a first cannula 530 and a second cannula 540 are coupled to the reservoir 510, while the reservoir 510 is further coupled to a pre-filled pouch 520.
  • the infusion management unit (IMU) 210 or 420 may be configured to include the first and second cannulas 530, 540, the reservoir 510 and the pre-filled pouch 520.
  • the pre-filled pouch is configured to hold therapeutic agent such as insulin to replenish the reservoir during the usage life of the patch pump 210, 410.
  • the first cannula 430 is coupled to a first reservoir 51OA, while the second cannula 540 is coupled to a second reservoir 51OB.
  • the infusion management unit (IMU) 210 or 420 may be configured to include the first and second cannulas 530, 540, each respectively coupled to the first and second reservoirs 510A, 510B.
  • the patch pump 210, 410 within the scope of the present invention may include additional components that are conf ⁇ gured to assist and/or improve the therapeutic agent delivery and analyte monitoring.
  • additional components may include, but are not limited to, one or more power supplies such as batteries, one or more user input units (e.g., mechanical and/or electromechanical, button, switch, and the like), one or more user output units (e.g., a visual indicator, an audible alert, a vibratory alert, or a combination thereof), one or more additional redundant microprocessors to protect from failure modes of the patch pump 210, 410, or a leakage sensor for detecting any leakage of the therapeutic agent or any other fluid within the housing of the patch pump 210, 410 that may damage the internal components.
  • one or more power supplies such as batteries
  • one or more user input units e.g., mechanical and/or electromechanical, button, switch, and the like
  • user output units e.g., a visual indicator, an audible alert, a vibr
  • an integrated therapy management system in one embodiment includes a first cannula for transcutaneous placement under a skin layer of a patient at a first infusion site for a first time period, a second cannula for transcutaneous placement under the skin layer of the patient at a second infusion site for a second time period, and an analyte sensor configured for fluid contact with an analyte of the patient for a predetermined time period, where the first cannula and the second cannula are configured to deliver a therapeutic agent to the patient during the predetermined time period.
  • first cannula, the second cannula and the sensor are coupled to the housing.
  • first cannula and the sensor are coupled to the housing, and further, where second cannula may be connected to the housing by an infusion tubing.
  • the first infusion site and the second infusion site may be separated by a predetermined distance.
  • the predetermined time period may include approximately seven days.
  • the system may also include a reservoir coupled to the first cannula and the second cannula.
  • first reservoir coupled to the first cannula
  • second reservoir coupled to the second cannula
  • the sensor may include an analyte sensor, and the therapeutic agent may include insulin.
  • a method in accordance with another embodiment includes positioning a portion of a first cannula under the skin of a patient, positioning a portion of a sensor under the skin of the patient, positioning a portion of a second cannula under the skin of a patient, and withdrawing the first cannula from the patient while retaining the sensor position under the skin of the patient. The positioning the portion of the first cannula and the positioning the portion of the sensor may be substantially simultaneously performed.
  • the senor may be positioned under the skin of the patient for approximately seven days.
  • An integrated therapy management system in accordance with still another embodiment includes an on-body micropump including a first cannula for transcutaneous placement under a skin layer of a patient at a first infusion site for a first time period, a second cannula for transcutaneous placement under the skin layer of the patient at a second infusion site for a second time period, an analyte sensor configured for fluid contact with an analyte of the patient for a predetermined time period, and a controller in signal communication with the on-body micropump, the controller configured to transmit one or more signals to the micropump to control the delivery of a therapeutic agent to the patient using one or more of the first cannula and the second cannula.
  • the micropump may further include a transmitter unit operatively coupled to the analyte sensor.
  • the controller may be configured to receive one or more signals associated with one or more analyte levels of the patient from the transmitter unit.
  • controller may be further configured to receive one or more signals associated with the therapeutic agent delivery.
  • controller may be in signal communication with the on-body micropump over a wireless communication link.
  • a kit in yet a further embodiment includes a first cannula for transcutaneous placement under a skin layer of a patient at a first infusion site for a first time period, a second cannula for transcutaneous placement under the skin layer of the patient at a second infusion site for a second time period, and an analyte sensor configured for fluid contact with an analyte of the patient for a predetermined time period, where the first cannula and the second cannula are configured to deliver a therapeutic agent to the patient during the predetermined time period.
  • the kit may also include a housing, where the first cannula, the second cannula and the sensor are coupled to the housing.
  • the kit may include a housing, where the first cannula and the sensor are coupled to the housing, and further, where second cannula may be connected to the housing by an infusion tubing.
  • the kit may include a reservoir coupled to the first cannula and the second cannula, or alternatively, the kit may include a first reservoir coupled to the first cannula, and a second reservoir coupled to the second cannula.

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Abstract

La présente invention concerne un procédé et un dispositif permettant d'obtenir la combinaison d'un système de surveillance d'analytes, d'une pompe de type timbre transdermique appliquée sur le corps et dotée de canules multiples, et d'un capteur intégrés.
EP20070799109 2006-06-30 2007-06-27 Capteur d'analyte et dispositif de perfusion intégrés, et procédés connexes Withdrawn EP2037796A2 (fr)

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US11/428,299 US9119582B2 (en) 2006-06-30 2006-06-30 Integrated analyte sensor and infusion device and methods therefor
PCT/US2007/072287 WO2008005780A2 (fr) 2006-06-30 2007-06-27 Capteur d'analyte et dispositif de perfusion intégrés, et procédés connexes

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Families Citing this family (164)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8066639B2 (en) 2003-06-10 2011-11-29 Abbott Diabetes Care Inc. Glucose measuring device for use in personal area network
US20190357827A1 (en) 2003-08-01 2019-11-28 Dexcom, Inc. Analyte sensor
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US9247900B2 (en) 2004-07-13 2016-02-02 Dexcom, Inc. Analyte sensor
EP1718198A4 (fr) 2004-02-17 2008-06-04 Therasense Inc Procede et systeme de communication de donnees dans un systeme de controle et de gestion de glucose en continu
WO2006127694A2 (fr) 2004-07-13 2006-11-30 Dexcom, Inc. Detecteur d'analyte
US20060020192A1 (en) 2004-07-13 2006-01-26 Dexcom, Inc. Transcutaneous analyte sensor
US7697967B2 (en) 2005-12-28 2010-04-13 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US20100331646A1 (en) * 2009-06-30 2010-12-30 Abbott Diabetes Care Inc. Health Management Devices and Methods
US9636450B2 (en) 2007-02-19 2017-05-02 Udo Hoss Pump system modular components for delivering medication and analyte sensing at seperate insertion sites
US8112240B2 (en) 2005-04-29 2012-02-07 Abbott Diabetes Care Inc. Method and apparatus for providing leak detection in data monitoring and management systems
US8353881B2 (en) * 2005-12-28 2013-01-15 Abbott Diabetes Care Inc. Infusion sets for the delivery of a therapeutic substance to a patient
US11298058B2 (en) 2005-12-28 2022-04-12 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US7981034B2 (en) 2006-02-28 2011-07-19 Abbott Diabetes Care Inc. Smart messages and alerts for an infusion delivery and management system
US7826879B2 (en) 2006-02-28 2010-11-02 Abbott Diabetes Care Inc. Analyte sensors and methods of use
US7653425B2 (en) 2006-08-09 2010-01-26 Abbott Diabetes Care Inc. Method and system for providing calibration of an analyte sensor in an analyte monitoring system
US8226891B2 (en) 2006-03-31 2012-07-24 Abbott Diabetes Care Inc. Analyte monitoring devices and methods therefor
US9675290B2 (en) 2012-10-30 2017-06-13 Abbott Diabetes Care Inc. Sensitivity calibration of in vivo sensors used to measure analyte concentration
US8140312B2 (en) 2007-05-14 2012-03-20 Abbott Diabetes Care Inc. Method and system for determining analyte levels
US8346335B2 (en) 2008-03-28 2013-01-01 Abbott Diabetes Care Inc. Analyte sensor calibration management
US8374668B1 (en) 2007-10-23 2013-02-12 Abbott Diabetes Care Inc. Analyte sensor with lag compensation
US8473022B2 (en) 2008-01-31 2013-06-25 Abbott Diabetes Care Inc. Analyte sensor with time lag compensation
US8219173B2 (en) 2008-09-30 2012-07-10 Abbott Diabetes Care Inc. Optimizing analyte sensor calibration
US9339217B2 (en) 2011-11-25 2016-05-17 Abbott Diabetes Care Inc. Analyte monitoring system and methods of use
US7618369B2 (en) 2006-10-02 2009-11-17 Abbott Diabetes Care Inc. Method and system for dynamically updating calibration parameters for an analyte sensor
US7630748B2 (en) 2006-10-25 2009-12-08 Abbott Diabetes Care Inc. Method and system for providing analyte monitoring
US8224415B2 (en) 2009-01-29 2012-07-17 Abbott Diabetes Care Inc. Method and device for providing offset model based calibration for analyte sensor
US20080004601A1 (en) * 2006-06-28 2008-01-03 Abbott Diabetes Care, Inc. Analyte Monitoring and Therapy Management System and Methods Therefor
US20090171269A1 (en) * 2006-06-29 2009-07-02 Abbott Diabetes Care, Inc. Infusion Device and Methods Therefor
US9119582B2 (en) * 2006-06-30 2015-09-01 Abbott Diabetes Care, Inc. Integrated analyte sensor and infusion device and methods therefor
US8932216B2 (en) * 2006-08-07 2015-01-13 Abbott Diabetes Care Inc. Method and system for providing data management in integrated analyte monitoring and infusion system
US8206296B2 (en) * 2006-08-07 2012-06-26 Abbott Diabetes Care Inc. Method and system for providing integrated analyte monitoring and infusion system therapy management
JP2010508091A (ja) 2006-10-26 2010-03-18 アボット ダイアベティス ケア インコーポレイテッド 検体センサの感度低下をリアルタイムで検出するための方法、システム、及びコンピュータプログラム製品
EP2124726A1 (fr) * 2006-12-22 2009-12-02 Medingo Ltd. Délivrance de fluide avec détection électrochimique in vivo d'analytes
US8930203B2 (en) 2007-02-18 2015-01-06 Abbott Diabetes Care Inc. Multi-function analyte test device and methods therefor
US8732188B2 (en) 2007-02-18 2014-05-20 Abbott Diabetes Care Inc. Method and system for providing contextual based medication dosage determination
US8123686B2 (en) 2007-03-01 2012-02-28 Abbott Diabetes Care Inc. Method and apparatus for providing rolling data in communication systems
ES2784736T3 (es) 2007-04-14 2020-09-30 Abbott Diabetes Care Inc Procedimiento y aparato para proporcionar el procesamiento y control de datos en un sistema de comunicación médica
CA2683863C (fr) 2007-04-14 2019-01-15 Abbott Diabetes Care Inc. Procede et appareil permettant le traitement et le controle des donnees dans un systeme de communication medical
WO2008130898A1 (fr) * 2007-04-14 2008-10-30 Abbott Diabetes Care, Inc. Procédé et appareil pour réaliser le traitement et la commande de données dans un système de communication médical
EP2146623B1 (fr) 2007-04-14 2014-01-08 Abbott Diabetes Care Inc. Procede et appareil pour realiser le traitement et la commande de donnees dans un systeme de communication medical
US8456301B2 (en) 2007-05-08 2013-06-04 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US20080281179A1 (en) * 2007-05-08 2008-11-13 Abbott Diabetes Care, Inc. Analyte monitoring system and methods
US7928850B2 (en) 2007-05-08 2011-04-19 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US20080278332A1 (en) * 2007-05-08 2008-11-13 Abbott Diabetes Care, Inc. Analyte monitoring system and methods
US20080281171A1 (en) * 2007-05-08 2008-11-13 Abbott Diabetes Care, Inc. Analyte monitoring system and methods
US8461985B2 (en) 2007-05-08 2013-06-11 Abbott Diabetes Care Inc. Analyte monitoring system and methods
US8665091B2 (en) 2007-05-08 2014-03-04 Abbott Diabetes Care Inc. Method and device for determining elapsed sensor life
US10002233B2 (en) 2007-05-14 2018-06-19 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8239166B2 (en) 2007-05-14 2012-08-07 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8103471B2 (en) 2007-05-14 2012-01-24 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8600681B2 (en) 2007-05-14 2013-12-03 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8444560B2 (en) 2007-05-14 2013-05-21 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8560038B2 (en) 2007-05-14 2013-10-15 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US9125548B2 (en) 2007-05-14 2015-09-08 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
US8260558B2 (en) 2007-05-14 2012-09-04 Abbott Diabetes Care Inc. Method and apparatus for providing data processing and control in a medical communication system
ES2747705T3 (es) * 2007-06-25 2020-03-11 Hoffmann La Roche Un sistema para evaluar la sensibilidad a la insulina
US8641618B2 (en) * 2007-06-27 2014-02-04 Abbott Diabetes Care Inc. Method and structure for securing a monitoring device element
US8085151B2 (en) 2007-06-28 2011-12-27 Abbott Diabetes Care Inc. Signal converting cradle for medical condition monitoring and management system
US8160900B2 (en) 2007-06-29 2012-04-17 Abbott Diabetes Care Inc. Analyte monitoring and management device and method to analyze the frequency of user interaction with the device
DK2173407T3 (da) * 2007-07-02 2020-04-27 Hoffmann La Roche Anordning til indgivelse af lægemiddel
US8834366B2 (en) 2007-07-31 2014-09-16 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor calibration
US20090063402A1 (en) * 2007-08-31 2009-03-05 Abbott Diabetes Care, Inc. Method and System for Providing Medication Level Determination
US8409093B2 (en) 2007-10-23 2013-04-02 Abbott Diabetes Care Inc. Assessing measures of glycemic variability
US8377031B2 (en) 2007-10-23 2013-02-19 Abbott Diabetes Care Inc. Closed loop control system with safety parameters and methods
MX2010008759A (es) * 2008-02-13 2010-08-31 Unomedical As Sellado entre una parte de canula y una trayectoria de fluido.
EP2259816B1 (fr) 2008-02-20 2015-10-21 Unomedical A/S Dispositif d'insertion munie d'une pièce mobile dans le sens horizontal
US9143569B2 (en) 2008-02-21 2015-09-22 Dexcom, Inc. Systems and methods for processing, transmitting and displaying sensor data
US8924159B2 (en) 2008-05-30 2014-12-30 Abbott Diabetes Care Inc. Method and apparatus for providing glycemic control
US8591410B2 (en) 2008-05-30 2013-11-26 Abbott Diabetes Care Inc. Method and apparatus for providing glycemic control
US8876755B2 (en) 2008-07-14 2014-11-04 Abbott Diabetes Care Inc. Closed loop control system interface and methods
US9943644B2 (en) * 2008-08-31 2018-04-17 Abbott Diabetes Care Inc. Closed loop control with reference measurement and methods thereof
US20100057040A1 (en) 2008-08-31 2010-03-04 Abbott Diabetes Care, Inc. Robust Closed Loop Control And Methods
US8986208B2 (en) * 2008-09-30 2015-03-24 Abbott Diabetes Care Inc. Analyte sensor sensitivity attenuation mitigation
US9149220B2 (en) 2011-04-15 2015-10-06 Dexcom, Inc. Advanced analyte sensor calibration and error detection
US9326707B2 (en) 2008-11-10 2016-05-03 Abbott Diabetes Care Inc. Alarm characterization for analyte monitoring devices and systems
US9375529B2 (en) * 2009-09-02 2016-06-28 Becton, Dickinson And Company Extended use medical device
CA2749320C (fr) 2009-01-12 2018-03-20 Becton, Dickinson And Company Ensemble de perfusion et/ou pompe a tampon presentant un catheter rigide integre a caracteristiques flexibles et/ou une fixation pour catheter flexible
US8103456B2 (en) 2009-01-29 2012-01-24 Abbott Diabetes Care Inc. Method and device for early signal attenuation detection using blood glucose measurements
US20100198196A1 (en) * 2009-01-30 2010-08-05 Abbott Diabetes Care, Inc. Therapy Delivery Device Programming Tool
ES2967456T3 (es) * 2009-02-26 2024-04-30 Abbott Diabetes Care Inc Procedimiento de calibración de un sensor de analitos
US8497777B2 (en) 2009-04-15 2013-07-30 Abbott Diabetes Care Inc. Analyte monitoring system having an alert
EP2425210A4 (fr) * 2009-04-28 2013-01-09 Abbott Diabetes Care Inc Étalonnage de détecteur d'analyte dynamique sur la base d'un profil de stabilité de détecteur
WO2010127050A1 (fr) 2009-04-28 2010-11-04 Abbott Diabetes Care Inc. Détection d'erreur dans des données de répétition critiques dans un système de capteur sans fil
WO2010138856A1 (fr) 2009-05-29 2010-12-02 Abbott Diabetes Care Inc. Systèmes d'antenne de dispositif médical comportant des configurations d'antenne externe
WO2011003036A2 (fr) 2009-07-02 2011-01-06 Dexcom, Inc. Capteurs d'analytes en continu et leurs procédés de fabrication
DK3689237T3 (da) * 2009-07-23 2021-08-16 Abbott Diabetes Care Inc Fremgangsmåde til fremstilling og system til kontinuerlig analytmåling
ES2888427T3 (es) 2009-07-23 2022-01-04 Abbott Diabetes Care Inc Gestión en tiempo real de los datos relativos al control fisiológico de los niveles de glucosa
CN102548598B (zh) 2009-08-07 2014-09-17 犹诺医药有限公司 具有传感器和一个或多个插管的传送装置
EP4147999A1 (fr) 2009-08-31 2023-03-15 Abbott Diabetes Care, Inc. Affichages pour dispositif médical
WO2011026147A1 (fr) 2009-08-31 2011-03-03 Abbott Diabetes Care Inc. Dispositif et procédés de traitement de signal d'analyte
WO2011026148A1 (fr) 2009-08-31 2011-03-03 Abbott Diabetes Care Inc. Système de surveillance de substance à analyser et procédés de gestion de l’énergie et du bruit
EP2482720A4 (fr) 2009-09-29 2014-04-23 Abbott Diabetes Care Inc Procédé et appareil de fourniture de fonction de notification dans des systèmes de surveillance de substance à analyser
CN102724913A (zh) 2009-09-30 2012-10-10 德克斯康公司 经皮分析物传感器
US8185181B2 (en) 2009-10-30 2012-05-22 Abbott Diabetes Care Inc. Method and apparatus for detecting false hypoglycemic conditions
US9662438B2 (en) * 2010-02-05 2017-05-30 Deka Products Limited Partnership Devices, methods and systems for wireless control of medical devices
US8635046B2 (en) 2010-06-23 2014-01-21 Abbott Diabetes Care Inc. Method and system for evaluating analyte sensor response characteristics
US10092229B2 (en) 2010-06-29 2018-10-09 Abbott Diabetes Care Inc. Calibration of analyte measurement system
US9950109B2 (en) 2010-11-30 2018-04-24 Becton, Dickinson And Company Slide-activated angled inserter and cantilevered ballistic insertion for intradermal drug infusion
US8814831B2 (en) 2010-11-30 2014-08-26 Becton, Dickinson And Company Ballistic microneedle infusion device
US8795230B2 (en) 2010-11-30 2014-08-05 Becton, Dickinson And Company Adjustable height needle infusion device
EP2673027A1 (fr) 2011-02-09 2013-12-18 Unomedical A/S Retrait d'une partie de canule à partir d'une partie de base
US10136845B2 (en) 2011-02-28 2018-11-27 Abbott Diabetes Care Inc. Devices, systems, and methods associated with analyte monitoring devices and devices incorporating the same
WO2013050277A1 (fr) 2011-10-05 2013-04-11 Unomedical A/S Introducteur pour insertion simultanée de plusieurs éléments transcutanés
WO2013066849A1 (fr) 2011-10-31 2013-05-10 Abbott Diabetes Care Inc. Mécanisme de prévention de fausse alarme de seuil de glucose à risque variable basé sur un modèle
US9980669B2 (en) 2011-11-07 2018-05-29 Abbott Diabetes Care Inc. Analyte monitoring device and methods
US8710993B2 (en) 2011-11-23 2014-04-29 Abbott Diabetes Care Inc. Mitigating single point failure of devices in an analyte monitoring system and methods thereof
US8790307B2 (en) 2011-12-01 2014-07-29 Picolife Technologies, Llc Drug delivery device and methods therefor
US8771229B2 (en) 2011-12-01 2014-07-08 Picolife Technologies, Llc Cartridge system for delivery of medicament
US10010274B2 (en) * 2011-12-16 2018-07-03 James Winkelman Systems, devices and methods for in situ calibration of implantable sensors
US10130759B2 (en) 2012-03-09 2018-11-20 Picolife Technologies, Llc Multi-ported drug delivery device having multi-reservoir cartridge system
WO2013149186A1 (fr) 2012-03-30 2013-10-03 Insulet Corporation Dispositif d'administration de fluide avec outil d'accès transcutané, mécanisme d'insertion et contrôle de glycémie destine à être utilisé avec le dispositif
EP2650032A1 (fr) 2012-04-11 2013-10-16 PharmaSens AG Mécanisme d'insertion d'aiguille sous-cutanée
US9883834B2 (en) 2012-04-16 2018-02-06 Farid Amirouche Medication delivery device with multi-reservoir cartridge system and related methods of use
US10245420B2 (en) 2012-06-26 2019-04-02 PicoLife Technologies Medicament distribution systems and related methods of use
US10132793B2 (en) 2012-08-30 2018-11-20 Abbott Diabetes Care Inc. Dropout detection in continuous analyte monitoring data during data excursions
US9968306B2 (en) 2012-09-17 2018-05-15 Abbott Diabetes Care Inc. Methods and apparatuses for providing adverse condition notification with enhanced wireless communication range in analyte monitoring systems
EP2901153A4 (fr) 2012-09-26 2016-04-27 Abbott Diabetes Care Inc Procédé et appareil d'amélioration de correction de retard pendant une mesure in vivo de concentration de substance à analyser avec des données de variabilité et de plage de concentration de substance à analyser
US20140155819A1 (en) * 2012-12-03 2014-06-05 PicoLife Technologies Medicament Delivery Systems
US10076285B2 (en) 2013-03-15 2018-09-18 Abbott Diabetes Care Inc. Sensor fault detection using analyte sensor data pattern comparison
US10433773B1 (en) 2013-03-15 2019-10-08 Abbott Diabetes Care Inc. Noise rejection methods and apparatus for sparsely sampled analyte sensor data
US9474475B1 (en) 2013-03-15 2016-10-25 Abbott Diabetes Care Inc. Multi-rate analyte sensor data collection with sample rate configurable signal processing
CA2933166C (fr) 2013-12-31 2020-10-27 Abbott Diabetes Care Inc. Capteur d'analytes auto-alimente et dispositifs utilisant ce dernier
WO2015153482A1 (fr) 2014-03-30 2015-10-08 Abbott Diabetes Care Inc. Procédé et appareil permettant de déterminer le début du repas et le pic prandial dans des systèmes de surveillance d'analyte
US10441717B2 (en) 2014-04-15 2019-10-15 Insulet Corporation Monitoring a physiological parameter associated with tissue of a host to confirm delivery of medication
US10004845B2 (en) 2014-04-18 2018-06-26 Becton, Dickinson And Company Split piston metering pump
US9416775B2 (en) 2014-07-02 2016-08-16 Becton, Dickinson And Company Internal cam metering pump
CN108024765B (zh) 2015-07-10 2021-06-11 雅培糖尿病护理公司 对于生理参数进行动态葡萄糖曲线响应的系统、装置和方法
WO2017091584A1 (fr) 2015-11-25 2017-06-01 Insulet Corporation Dispositif portable de distribution de médicament
US9954309B2 (en) 2016-07-20 2018-04-24 Intel Corporation Magnetic detachable electrical connections between circuits
US9735893B1 (en) * 2016-07-21 2017-08-15 Intel Corporation Patch system for in-situ therapeutic treatment
EP3730169B1 (fr) 2016-08-14 2023-08-02 Insulet Corporation Dispositif d'administration de medicaments avec detection de position du piston
US10039186B2 (en) 2016-09-16 2018-07-31 Intel Corporation Stretchable and flexible electrical substrate interconnections
US9893438B1 (en) 2016-09-30 2018-02-13 Intel Corporation Electrical connectors for high density attach to stretchable boards
WO2018067645A1 (fr) 2016-10-07 2018-04-12 Insulet Corporation Système d'administration à plusieurs étages
US10780217B2 (en) 2016-11-10 2020-09-22 Insulet Corporation Ratchet drive for on body delivery system
WO2018136699A1 (fr) 2017-01-19 2018-07-26 Insulet Corporation Réduction du volume de rétention de cartouche
CN108362826A (zh) 2017-01-26 2018-08-03 Bsh家用电器有限公司 食物处理时的空气质量
US20180214636A1 (en) * 2017-02-02 2018-08-02 Picolife Technologies, Llc Smart Cartridge System For Containing And Releasing Medicament With Pumping Mechanism And Compressible Reservoir
US11045603B2 (en) 2017-02-22 2021-06-29 Insulet Corporation Needle insertion mechanisms for drug containers
US10695485B2 (en) 2017-03-07 2020-06-30 Insulet Corporation Very high volume user filled drug delivery device
WO2018175489A1 (fr) 2017-03-21 2018-09-27 Abbott Diabetes Care Inc. Méthodes, dispositifs et système pour fournir un diagnostic et une thérapie pour un état diabétique
EP3654844A4 (fr) * 2017-07-21 2021-04-14 Abbott Diabetes Care Inc. Dispositifs, systèmes et procédés de délivrance de formulations solides
US10973978B2 (en) 2017-08-03 2021-04-13 Insulet Corporation Fluid flow regulation arrangements for drug delivery devices
EP3662161B1 (fr) 2017-08-03 2024-05-01 Insulet Corporation Micro-pompe à piston
US11786668B2 (en) 2017-09-25 2023-10-17 Insulet Corporation Drug delivery devices, systems, and methods with force transfer elements
WO2019067367A1 (fr) 2017-09-26 2019-04-04 Insulet Corporation Module de mécanisme d'aiguille pour dispositif d'administration de médicament
US11382540B2 (en) 2017-10-24 2022-07-12 Dexcom, Inc. Pre-connected analyte sensors
US11331022B2 (en) 2017-10-24 2022-05-17 Dexcom, Inc. Pre-connected analyte sensors
US11147931B2 (en) 2017-11-17 2021-10-19 Insulet Corporation Drug delivery device with air and backflow elimination
US10874803B2 (en) 2018-05-31 2020-12-29 Insulet Corporation Drug cartridge with drive system
EP3801682A1 (fr) 2018-06-06 2021-04-14 Insulet Corporation Pompe à navette linéaire pour l'administration de médicament
US11241532B2 (en) 2018-08-29 2022-02-08 Insulet Corporation Drug delivery system with sensor having optimized communication and infusion site
CN113167258B (zh) 2018-11-28 2023-05-12 英赛罗公司 药物输送往复泵系统和阀组件
US11776684B2 (en) 2019-09-26 2023-10-03 Pacesetter, Inc Method and device for managing energy usage by a medical device
US11369735B2 (en) 2019-11-05 2022-06-28 Insulet Corporation Component positioning of a linear shuttle pump
US20230111253A1 (en) * 2020-02-21 2023-04-13 The Regents Of The University Of California Microneedle array sensor patch for continuous multi-analyte detection
US11806505B2 (en) 2020-12-02 2023-11-07 Medtronic Minimed, Inc. Single-site insertion of multiple medical devices
US11738140B2 (en) 2021-01-15 2023-08-29 Medtronic Minimed, Inc. Insertion device with linkage assembly
US11944786B2 (en) 2021-01-18 2024-04-02 Medtronic Minimed, Inc. Infusion device
US20220330860A1 (en) 2021-04-14 2022-10-20 Neoenta LLC Dermal patch system
US11877848B2 (en) 2021-11-08 2024-01-23 Satio, Inc. Dermal patch for collecting a physiological sample
US11964121B2 (en) 2021-10-13 2024-04-23 Satio, Inc. Mono dose dermal patch for pharmaceutical delivery
US11510602B1 (en) 2021-11-08 2022-11-29 Satio, Inc. Dermal patch for collecting a physiological sample

Family Cites Families (343)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US571761A (en) 1896-11-24 Electric-light-cord adjuster
US1555351A (en) 1925-05-29 1925-09-29 Boynton Alexander Cable tightener
US2587707A (en) * 1950-03-10 1952-03-04 Franklin J Dever Electric cord slack storage device
US2755036A (en) 1953-07-03 1956-07-17 Terho Mikko Jooseppi Cable drum
US3180221A (en) 1963-06-19 1965-04-27 Dresser Ind Gun perforator
US3208121A (en) 1963-10-03 1965-09-28 James C Price Storage reel
US3320954A (en) 1963-12-30 1967-05-23 Pharmaseal Lab Hypodermic syringe with breakable polypropylene needle adaptor
US4725010A (en) * 1986-07-18 1988-02-16 Essex Group, Inc. Control apparatus and method
US4003379A (en) * 1974-04-23 1977-01-18 Ellinwood Jr Everett H Apparatus and method for implanted self-powered medication dispensing
US3923060A (en) * 1974-04-23 1975-12-02 Jr Everett H Ellinwood Apparatus and method for implanted self-powered medication dispensing having timing and evaluator means
US3924819A (en) 1974-06-11 1975-12-09 Edward F Lapinskas Electrical utility cord storage and shortening device
US4055175A (en) * 1976-05-07 1977-10-25 Miles Laboratories, Inc. Blood glucose control apparatus
US4076182A (en) * 1977-01-10 1978-02-28 Armco Steel Corporation Variable speed wire spooler
US4151845A (en) * 1977-11-25 1979-05-01 Miles Laboratories, Inc. Blood glucose control apparatus
US4226235A (en) * 1979-01-25 1980-10-07 Survival Technology, Inc. Plural injecting device
US4360019A (en) * 1979-02-28 1982-11-23 Andros Incorporated Implantable infusion device
US4286039A (en) 1979-05-15 1981-08-25 Savin Corporation Method and apparatus for removing excess developing liquid from photoconductive surfaces
CA1169323A (fr) 1980-06-03 1984-06-19 Anthony M. Albisser Dispositif de perfusion d'insuline
US4387863A (en) 1981-12-17 1983-06-14 Western Electric Company, Inc. Spool assembly
US4561443A (en) 1983-03-08 1985-12-31 The Johns Hopkins University Coherent inductive communications link for biomedical applications
US4675346A (en) 1983-06-20 1987-06-23 Loctite Corporation UV curable silicone rubber compositions
US4685903A (en) 1984-01-06 1987-08-11 Pacesetter Infusion, Ltd. External infusion pump apparatus
US4886505A (en) 1985-06-07 1989-12-12 Becton, Dickinson And Company Antimicrobial surfaces and inhibition of microorganism growth thereby
US5349852A (en) 1986-03-04 1994-09-27 Deka Products Limited Partnership Pump controller using acoustic spectral analysis
US4629145A (en) 1986-03-28 1986-12-16 Essex Group, Inc. Control of traversing guide in strand winding apparatus
US4667896A (en) 1986-06-05 1987-05-26 Siecor Corporation Three flange cable spool
AT391998B (de) * 1987-02-02 1990-12-27 Falko Dr Skrabal Vorrichtung zur bestimmung der konzentration zumindest einer medizinischen substanz in lebenden organismen
US4802638A (en) * 1987-07-29 1989-02-07 Motorola, Inc. Cord stowage apparatus
US5006110A (en) 1987-12-01 1991-04-09 Pacesetter Infusion, Ltd. Air-in-line detector infusion system
US5019096A (en) 1988-02-11 1991-05-28 Trustees Of Columbia University In The City Of New York Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same
US5516821A (en) 1988-09-15 1996-05-14 Argus Chemical Corporation Polymer stabilizer and polymer compositions stabilized therewith
US5165952A (en) 1989-01-18 1992-11-24 Becton, Dickinson And Company Anti-infective and antithrombogenic medical articles and method for their preparation
US5089112A (en) 1989-03-20 1992-02-18 Associated Universities, Inc. Electrochemical biosensor based on immobilized enzymes and redox polymers
US4953552A (en) 1989-04-21 1990-09-04 Demarzo Arthur P Blood glucose monitoring system
EP0429842B1 (fr) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Dispositif d'administration transcutanée de médicaments à base de protéine ou de peptide
US5261896A (en) * 1990-01-10 1993-11-16 Rochester Medical Corporation Sustained release bactericidal cannula
US5162407A (en) 1990-03-06 1992-11-10 Investors Diversified Capital, Inc. Silicone rubber sealant composition
US5109577A (en) 1990-07-19 1992-05-05 The United States Of America As Represented By The Secretary Of The Navy Cable-line shortening device
US5067665A (en) 1990-11-13 1991-11-26 Hughes Aircraft Company Base layer for an optical fiber wound pack
AU1257392A (en) 1991-01-11 1992-08-17 Health Innovations Inc. Method and apparatus to control diet and weight using human behavior modification techniques
US5266359A (en) 1991-01-14 1993-11-30 Becton, Dickinson And Company Lubricative coating composition, article and assembly containing same and method thereof
US5344411A (en) 1991-02-27 1994-09-06 Leonard Bloom Method and device for inhibiting HIV, hepatitis B and other viruses and germs when using a catheter in a medical environment
US5437656A (en) 1991-02-27 1995-08-01 Leonard Bloom Method and device for inhibiting H.I.V. hepatitis B and other viruses and germs when using a needle, scalpel and other sharp instrument in a medical environment
US5593852A (en) 1993-12-02 1997-01-14 Heller; Adam Subcutaneous glucose electrode
GB9106678D0 (en) 1991-03-28 1991-05-15 Ferguson Mark W J Wound healing
US5236143A (en) 1991-10-23 1993-08-17 Dragon Bradley P Intravenous tubing retractor apparatus
US5209414A (en) 1991-10-30 1993-05-11 Dana Corporation Apparatus for precisely winding a coil of wire
US5601435A (en) 1994-11-04 1997-02-11 Intercare Method and apparatus for interactively monitoring a physiological condition and for interactively providing health related information
US5918603A (en) 1994-05-23 1999-07-06 Health Hero Network, Inc. Method for treating medical conditions using a microprocessor-based video game
US5899855A (en) 1992-11-17 1999-05-04 Health Hero Network, Inc. Modular microprocessor-based health monitoring system
US5956501A (en) 1997-01-10 1999-09-21 Health Hero Network, Inc. Disease simulation system and method
US5284425A (en) * 1992-11-18 1994-02-08 The Lee Company Fluid metering pump
GB9308294D0 (en) 1993-04-22 1993-06-09 Gilbarco Ltd Error detection apparatus for an electro-optic display
US6835898B2 (en) 1993-11-16 2004-12-28 Formfactor, Inc. Electrical contact structures formed by configuring a flexible wire to have a springable shape and overcoating the wire with at least one layer of a resilient conductive material, methods of mounting the contact structures to electronic components, and applications for employing the contact structures
US6336269B1 (en) 1993-11-16 2002-01-08 Benjamin N. Eldridge Method of fabricating an interconnection element
US5497772A (en) 1993-11-19 1996-03-12 Alfred E. Mann Foundation For Scientific Research Glucose monitoring system
US5842473A (en) 1993-11-29 1998-12-01 Life Imaging Systems Three-dimensional imaging system
US6206829B1 (en) 1996-07-12 2001-03-27 First Opinion Corporation Computerized medical diagnostic and treatment advice system including network access
US5536249A (en) 1994-03-09 1996-07-16 Visionary Medical Products, Inc. Pen-type injector with a microprocessor and blood characteristic monitor
US5390671A (en) * 1994-03-15 1995-02-21 Minimed Inc. Transcutaneous sensor insertion set
EP0672427A1 (fr) * 1994-03-17 1995-09-20 Siemens-Elema AB Dispositif de perfusion de médicament
US5569186A (en) * 1994-04-25 1996-10-29 Minimed Inc. Closed loop infusion pump system with removable glucose sensor
US5494562A (en) 1994-06-27 1996-02-27 Ciba Corning Diagnostics Corp. Electrochemical sensors
US7027859B1 (en) 1994-09-26 2006-04-11 Alza Corporation Electrotransport delivery device having improved safety and reduced abuse potential
US6045671A (en) 1994-10-18 2000-04-04 Symyx Technologies, Inc. Systems and methods for the combinatorial synthesis of novel materials
FI111215B (fi) 1995-05-31 2003-06-30 Polar Electro Oy Telemetristä tiedonsiirtoa käyttävä menetelmä ja järjestelmä sydänsykkeen mittaukseen
US5584813A (en) 1995-06-07 1996-12-17 Minimed Inc. Subcutaneous injection set
US6083248A (en) 1995-06-23 2000-07-04 Medtronic, Inc. World wide patient location and data telemetry system for implantable medical devices
US5673694A (en) 1995-08-08 1997-10-07 Henry Ford Health System Method and apparatus for continuous measurement of central venous oxygen saturation
US5711685A (en) 1996-01-23 1998-01-27 Tescorp Seismic Products, Inc. Electrical connector having removable seal at cable entry end
US5763787A (en) 1996-09-05 1998-06-09 Rosemont Inc. Carrier assembly for fluid sensor
US5770208A (en) 1996-09-11 1998-06-23 Nabi Staphylococcus aureus B-linked hexosamine antigen
US5738220A (en) 1996-09-30 1998-04-14 Pacesetter, Inc. Distal tip protector cap
US5964993A (en) 1996-12-19 1999-10-12 Implanted Biosystems Inc. Glucose sensor
US6093172A (en) 1997-02-05 2000-07-25 Minimed Inc. Injector for a subcutaneous insertion set
US6741877B1 (en) 1997-03-04 2004-05-25 Dexcom, Inc. Device and method for determining analyte levels
US7899511B2 (en) 2004-07-13 2011-03-01 Dexcom, Inc. Low oxygen in vivo analyte sensor
US7192450B2 (en) * 2003-05-21 2007-03-20 Dexcom, Inc. Porous membranes for use with implantable devices
US6862465B2 (en) 1997-03-04 2005-03-01 Dexcom, Inc. Device and method for determining analyte levels
US20050033132A1 (en) 1997-03-04 2005-02-10 Shults Mark C. Analyte measuring device
US6558321B1 (en) 1997-03-04 2003-05-06 Dexcom, Inc. Systems and methods for remote monitoring and modulation of medical devices
US7657297B2 (en) * 2004-05-03 2010-02-02 Dexcom, Inc. Implantable analyte sensor
US6001067A (en) 1997-03-04 1999-12-14 Shults; Mark C. Device and method for determining analyte levels
US6645178B1 (en) 1997-04-21 2003-11-11 Larry G. Junker Apparatus for inserting medical device
US7267665B2 (en) 1999-06-03 2007-09-11 Medtronic Minimed, Inc. Closed loop system for controlling insulin infusion
US5954643A (en) 1997-06-09 1999-09-21 Minimid Inc. Insertion set for a transcutaneous sensor
US6558351B1 (en) 1999-06-03 2003-05-06 Medtronic Minimed, Inc. Closed loop system for controlling insulin infusion
US5823802A (en) 1997-07-30 1998-10-20 General Motors Corporation Electrical connector with combination seal and contact member
US6259937B1 (en) 1997-09-12 2001-07-10 Alfred E. Mann Foundation Implantable substrate sensor
US6579690B1 (en) 1997-12-05 2003-06-17 Therasense, Inc. Blood analyte monitoring through subcutaneous measurement
US5988545A (en) 1997-12-30 1999-11-23 Minerals Technologies, Inc. Method for storing and dispensing cored wire
US6819862B1 (en) 1998-01-21 2004-11-16 Kabushiki Kaisha Toshiba Video data recording medium, video data recording apparatus and video data playback apparatus
US6198969B1 (en) 1998-02-12 2001-03-06 Advanced Bionics Corporation Implantable connector for multi-output neurostimulators
US6103033A (en) 1998-03-04 2000-08-15 Therasense, Inc. Process for producing an electrochemical biosensor
US6134461A (en) 1998-03-04 2000-10-17 E. Heller & Company Electrochemical analyte
US5975120A (en) 1998-03-05 1999-11-02 Novosel; Lorraine Ley Automatically retractable gas tubing feed spool
US6197181B1 (en) 1998-03-20 2001-03-06 Semitool, Inc. Apparatus and method for electrolytically depositing a metal on a microelectronic workpiece
US7647237B2 (en) 1998-04-29 2010-01-12 Minimed, Inc. Communication station and software for interfacing with an infusion pump, analyte monitor, analyte meter, or the like
US6175752B1 (en) 1998-04-30 2001-01-16 Therasense, Inc. Analyte monitoring device and methods of use
US6736797B1 (en) 1998-06-19 2004-05-18 Unomedical A/S Subcutaneous infusion set
US7798993B2 (en) 1998-07-29 2010-09-21 Becton, Dickinson And Company Single use syringe
US7077328B2 (en) 1998-07-31 2006-07-18 Abbott Laboratories Analyte test instrument system including data management system
US6248067B1 (en) 1999-02-05 2001-06-19 Minimed Inc. Analyte sensor and holter-type monitor system and method of using the same
US6554798B1 (en) 1998-08-18 2003-04-29 Medtronic Minimed, Inc. External infusion device with remote programming, bolus estimator and/or vibration alarm capabilities
US6254586B1 (en) * 1998-09-25 2001-07-03 Minimed Inc. Method and kit for supplying a fluid to a subcutaneous placement site
EP1119285A1 (fr) 1998-10-08 2001-08-01 Minimed Inc. Systeme de surveillance par telemesure d'une caracteristique
JP2002536103A (ja) 1999-02-12 2002-10-29 シグナス， インコーポレイテッド 生物学的系に存在する分析物の頻繁な測定のためのデバイスおよび方法
US6360888B1 (en) 1999-02-25 2002-03-26 Minimed Inc. Glucose sensor package system
US6237394B1 (en) 1999-02-25 2001-05-29 Redwood Microsystems, Inc. Apparatus and method for correcting drift in a sensor
US6424847B1 (en) 1999-02-25 2002-07-23 Medtronic Minimed, Inc. Glucose monitor calibration methods
WO2000049942A2 (fr) 1999-02-25 2000-08-31 Minimed, Inc. Element de branchement test et cable pour dispositif de mesure du niveau de glucose
US20010041870A1 (en) 1999-03-09 2001-11-15 Edward M. Gillis Implantable device for access to a treatment site
US6285897B1 (en) 1999-04-07 2001-09-04 Endonetics, Inc. Remote physiological monitoring system
DE19925910B4 (de) 1999-06-07 2005-04-28 Siemens Ag Verfahren zum Be- oder Verarbeiten von Daten
US6471689B1 (en) 1999-08-16 2002-10-29 Thomas Jefferson University Implantable drug delivery catheter system with capillary interface
US7113821B1 (en) * 1999-08-25 2006-09-26 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery
US7133717B2 (en) * 1999-08-25 2006-11-07 Johnson & Johnson Consumer Companies, Inc. Tissue electroperforation for enhanced drug delivery and diagnostic sampling
US7121409B1 (en) 1999-09-02 2006-10-17 Snap Pak Industries (Aust) Pty Ltd. Dispensing sachet by bending and method of sachet manufacture
US6377829B1 (en) 1999-12-09 2002-04-23 Masimo Corporation Resposable pulse oximetry sensor
US6733446B2 (en) * 2000-01-21 2004-05-11 Medtronic Minimed, Inc. Ambulatory medical apparatus and method using a telemetry system with predefined reception listening periods
US7369635B2 (en) 2000-01-21 2008-05-06 Medtronic Minimed, Inc. Rapid discrimination preambles and methods for using the same
CA2396749C (fr) 2000-01-21 2011-07-19 Medical Research Group, Inc. Dispositif et procede medical a application ambulatoire comprenant un logiciel de commande modifiable par telemetrie
WO2001054753A2 (fr) 2000-01-21 2001-08-02 Medical Research Group, Inc. Appareil medical ambulatoire commande par microprocesseur pourvu d'un dispositif de communication portable
US6484045B1 (en) 2000-02-10 2002-11-19 Medtronic Minimed, Inc. Analyte sensor and method of making the same
US7003336B2 (en) * 2000-02-10 2006-02-21 Medtronic Minimed, Inc. Analyte sensor method of making the same
DE60130536T2 (de) 2000-02-10 2008-06-26 Medtronic MiniMed, Inc., Northridge Analytensensor
US7890295B2 (en) * 2000-02-23 2011-02-15 Medtronic Minimed, Inc. Real time self-adjusting calibration algorithm
US6895263B2 (en) 2000-02-23 2005-05-17 Medtronic Minimed, Inc. Real time self-adjusting calibration algorithm
US6946446B2 (en) 2000-02-24 2005-09-20 Abbott Laboratories Anti-infective agents useful against multidrug-resistant strains of bacteria
US6706159B2 (en) 2000-03-02 2004-03-16 Diabetes Diagnostics Combined lancet and electrochemical analyte-testing apparatus
US6498941B1 (en) 2000-03-09 2002-12-24 Advanced Cardiovascular Systems, Inc. Catheter based probe and method of using same for detecting chemical analytes
US6485461B1 (en) 2000-04-04 2002-11-26 Insulet, Inc. Disposable infusion device
US6641562B1 (en) 2000-05-10 2003-11-04 Hps Medical, Inc. Apparatus and method of intravenous fluid infusion
AU2001263022A1 (en) 2000-05-12 2001-11-26 Therasense, Inc. Electrodes with multilayer membranes and methods of using and making the electrodes
WO2001091902A2 (fr) 2000-05-30 2001-12-06 Massachusetts Institute Of Technology Procedes et dispositifs de fermeture hermetique de reservoirs a puce
US20020016719A1 (en) * 2000-06-19 2002-02-07 Nemeth Louis G. Methods and systems for providing medical data to a third party in accordance with configurable distribution parameters
JP4055926B2 (ja) * 2000-08-14 2008-03-05 テルモ株式会社 輸液ポンプ
US6882940B2 (en) 2000-08-18 2005-04-19 Cygnus, Inc. Methods and devices for prediction of hypoglycemic events
WO2002015778A1 (fr) 2000-08-18 2002-02-28 Cygnus, Inc. Systeme permettant d'augmenter l'alarme d'un dispositif de surveillance d'analyte
US6669669B2 (en) 2001-10-12 2003-12-30 Insulet Corporation Laminated patient infusion device
WO2002020073A2 (fr) 2000-09-08 2002-03-14 Insulet Corporation Dispositifs, systemes et procedes de perfusion d'un patient
US6603995B1 (en) 2000-10-19 2003-08-05 Reynolds Medical Limited Body monitoring apparatus
DE60132507T2 (de) 2000-11-09 2008-12-24 Insulet Corp., Beverly Gerät zur transkutanen Abgabe von Medikamenten
WO2002039086A2 (fr) 2000-11-13 2002-05-16 Nipro Diabetes Systems Système de détection du glucose
US20020147135A1 (en) 2000-12-21 2002-10-10 Oliver Schnell Method and device for producing an adapted travel treatment plan for administering a medicine in the event of a long-haul journey
CN1292702C (zh) 2000-12-21 2007-01-03 茵斯莱特有限公司 医学装置遥控器及方法
US6616626B2 (en) 2000-12-21 2003-09-09 Scimed Life Systems, Inc. Infusion devices and method
US6560471B1 (en) 2001-01-02 2003-05-06 Therasense, Inc. Analyte monitoring device and methods of use
JP2004532670A (ja) 2001-02-22 2004-10-28 インシュレット コーポレイション モジュール式の輸液装置及び方法
WO2002079207A2 (fr) * 2001-04-02 2002-10-10 California Institute Of Technology Amido ligands bidentes et tridentes elabores par couplage palladium0, et metallation de ces ligands visant a former des catalyseurs metal-amido
US7083593B2 (en) * 2001-04-18 2006-08-01 Advanced Bionics Corporation Programmable implantable pump with accessory reservoirs and multiple independent lumen catheter
AUPR632301A0 (en) 2001-07-11 2001-08-02 Chee, Frederick Howe-Hui Infusion apparatus for regulating blood glucose levels
US6702857B2 (en) 2001-07-27 2004-03-09 Dexcom, Inc. Membrane for use with implantable devices
US20030032874A1 (en) 2001-07-27 2003-02-13 Dexcom, Inc. Sensor head for use with implantable devices
US6740072B2 (en) * 2001-09-07 2004-05-25 Medtronic Minimed, Inc. System and method for providing closed loop infusion formulation delivery
US20030055380A1 (en) * 2001-09-19 2003-03-20 Flaherty J. Christopher Plunger for patient infusion device
US6986756B2 (en) 2001-09-24 2006-01-17 Becton, Dickinson And Company Single use syringe and plunger rod locking device therefor
US20030073414A1 (en) 2001-10-15 2003-04-17 Stephen P. Capps Textual and telephony dual input device
US7429258B2 (en) 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
US6598824B2 (en) 2001-11-20 2003-07-29 Trombetta, Llc Electrical and mechanical coil system for dual and single action solenoids
US6990336B2 (en) 2001-11-29 2006-01-24 Qualcomm Incorporated Mobile reporting module employing timing and message consolidation to economize transmissions
DE60209784T2 (de) 2001-12-06 2006-11-30 Cardinal Health 303, Inc., San Diego Infusionsvorrichtung mit co2 überwachung
US7204823B2 (en) 2001-12-19 2007-04-17 Medtronic Minimed, Inc. Medication delivery system and monitor
US7399277B2 (en) * 2001-12-27 2008-07-15 Medtronic Minimed, Inc. System for monitoring physiological characteristics
US7022072B2 (en) 2001-12-27 2006-04-04 Medtronic Minimed, Inc. System for monitoring physiological characteristics
US7524309B2 (en) 2001-12-28 2009-04-28 Medtronic Minimed, Inc. Variable length flexible conduit feeder
US20030144362A1 (en) 2002-01-28 2003-07-31 Utterberg David S. High viscosity antibacterials for cannulae
US6887270B2 (en) 2002-02-08 2005-05-03 Boston Scientific Scimed, Inc. Implantable or insertable medical device resistant to microbial growth and biofilm formation
US7004928B2 (en) 2002-02-08 2006-02-28 Rosedale Medical, Inc. Autonomous, ambulatory analyte monitor or drug delivery device
US7613491B2 (en) 2002-05-22 2009-11-03 Dexcom, Inc. Silicone based membranes for use in implantable glucose sensors
US8260393B2 (en) * 2003-07-25 2012-09-04 Dexcom, Inc. Systems and methods for replacing signal data artifacts in a glucose sensor data stream
US8364229B2 (en) 2003-07-25 2013-01-29 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US8010174B2 (en) * 2003-08-22 2011-08-30 Dexcom, Inc. Systems and methods for replacing signal artifacts in a glucose sensor data stream
US20030212379A1 (en) 2002-02-26 2003-11-13 Bylund Adam David Systems and methods for remotely controlling medication infusion and analyte monitoring
US6744350B2 (en) 2002-02-28 2004-06-01 Smiths Medical Md, Inc. Insulin pump having missed meal bolus alarm
US6852104B2 (en) 2002-02-28 2005-02-08 Smiths Medical Md, Inc. Programmable insulin pump
US6692457B2 (en) 2002-03-01 2004-02-17 Insulet Corporation Flow condition sensor assembly for patient infusion device
US6830558B2 (en) 2002-03-01 2004-12-14 Insulet Corporation Flow condition sensor assembly for patient infusion device
US6936006B2 (en) 2002-03-22 2005-08-30 Novo Nordisk, A/S Atraumatic insertion of a subcutaneous device
US7052251B2 (en) 2002-04-22 2006-05-30 Medtronic Minimed, Inc. Shape memory alloy wire driven positive displacement micropump with pulsatile output
US6960192B1 (en) 2002-04-23 2005-11-01 Insulet Corporation Transcutaneous fluid delivery system
US20050238507A1 (en) 2002-04-23 2005-10-27 Insulet Corporation Fluid delivery device
US20040153032A1 (en) 2002-04-23 2004-08-05 Garribotto John T. Dispenser for patient infusion device
US6656159B2 (en) 2002-04-23 2003-12-02 Insulet Corporation Dispenser for patient infusion device
US6656158B2 (en) 2002-04-23 2003-12-02 Insulet Corporation Dispenser for patient infusion device
WO2003090816A2 (fr) * 2002-04-24 2003-11-06 Kevin Marchitto Dispositif de commande a retroaction pour administration transcutanee de medicament et utilisations associees
US6902207B2 (en) 2002-05-01 2005-06-07 Medtronic Minimed, Inc. Self sealing disconnect device
US7226978B2 (en) 2002-05-22 2007-06-05 Dexcom, Inc. Techniques to improve polyurethane membranes for implantable glucose sensors
US20080132842A1 (en) 2002-06-06 2008-06-05 Flaherty J Christopher Plunger assembly for patient infusion device
US6723072B2 (en) 2002-06-06 2004-04-20 Insulet Corporation Plunger assembly for patient infusion device
US20040010207A1 (en) * 2002-07-15 2004-01-15 Flaherty J. Christopher Self-contained, automatic transcutaneous physiologic sensing system
US7018360B2 (en) * 2002-07-16 2006-03-28 Insulet Corporation Flow restriction system and method for patient infusion device
US7171312B2 (en) * 2002-07-19 2007-01-30 Smiths Detection, Inc. Chemical and biological agent sensor array detectors
AU2003302720B9 (en) 2002-07-19 2008-08-21 Smiths Detection-Pasadena, Inc. Non-specific sensor array detectors
US7278983B2 (en) 2002-07-24 2007-10-09 Medtronic Minimed, Inc. Physiological monitoring device for controlling a medication infusion device
US8512276B2 (en) 2002-07-24 2013-08-20 Medtronic Minimed, Inc. System for providing blood glucose measurements to an infusion device
US20040155770A1 (en) 2002-08-22 2004-08-12 Nelson Carl V. Audible alarm relay system
US6865641B2 (en) * 2002-08-29 2005-03-08 International Business Machines Corporation Method and apparatus for non-volatile display of information for an electronic device
US7128727B2 (en) 2002-09-30 2006-10-31 Flaherty J Christopher Components and methods for patient infusion device
US20040122530A1 (en) 2002-09-30 2004-06-24 Steffen Hansen Indicating device with estimating feature
US7144384B2 (en) 2002-09-30 2006-12-05 Insulet Corporation Dispenser components and methods for patient infusion device
AU2003269844A1 (en) * 2002-10-07 2004-04-23 Novo Nordisk A/S Needle device comprising a plurality of needles
EP2383470A1 (fr) 2002-10-09 2011-11-02 Abbott Diabetes Care Inc. Pompe à plongeur avec entraînement par un alliage à mémoire de forme
WO2004034883A2 (fr) 2002-10-15 2004-04-29 Medtronic Inc. Synchronisation et etalonnage d'horloges pour dispositif medical et horloge etalonnee
US7381184B2 (en) 2002-11-05 2008-06-03 Abbott Diabetes Care Inc. Sensor inserter assembly
US6896666B2 (en) 2002-11-08 2005-05-24 Kochamba Family Trust Cutaneous injection delivery under suction
FR2848542B1 (fr) 2002-12-13 2006-06-30 France Telecom Dispositif de conditionnement et de devidage de cable
US7009511B2 (en) 2002-12-17 2006-03-07 Cardiac Pacemakers, Inc. Repeater device for communications with an implantable medical device
US7052472B1 (en) 2002-12-18 2006-05-30 Dsp Diabetes Sentry Products, Inc. Systems and methods for detecting symptoms of hypoglycemia
US7134999B2 (en) 2003-04-04 2006-11-14 Dexcom, Inc. Optimized sensor geometry for an implantable glucose sensor
US20050038674A1 (en) * 2003-04-15 2005-02-17 Braig James R. System and method for managing a chronic medical condition
WO2004091711A2 (fr) 2003-04-15 2004-10-28 Sda Product, Inc. Systeme de catheter de dialyse
US7306580B2 (en) 2003-04-16 2007-12-11 Cook Incorporated Medical device with therapeutic agents
US20050182366A1 (en) 2003-04-18 2005-08-18 Insulet Corporation Method For Visual Output Verification
CA2520880A1 (fr) 2003-04-18 2004-11-04 Insulet Corporation Interface utilisateur pour unite de telecommande de pompe de perfusion et son procede d'utilisation
WO2004098682A2 (fr) 2003-05-08 2004-11-18 Novo Nordisk A/S Unite aiguille pivotante
US7875293B2 (en) * 2003-05-21 2011-01-25 Dexcom, Inc. Biointerface membranes incorporating bioactive agents
US20040254433A1 (en) 2003-06-12 2004-12-16 Bandis Steven D. Sensor introducer system, apparatus and method
WO2005007223A2 (fr) * 2003-07-16 2005-01-27 Sasha John Systemes et procedes d'administration programmable de medicaments pour l'administration de fluides et de concentrations multiples
US7424318B2 (en) 2003-12-05 2008-09-09 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
JP4708342B2 (ja) 2003-07-25 2011-06-22 デックスコム・インコーポレーテッド 埋設可能な装置に用いる酸素増大膜システム
WO2005012873A2 (fr) 2003-07-25 2005-02-10 Dexcom, Inc. Systemes d'electrodes pour detecteurs electrochimiques
US20050176136A1 (en) 2003-11-19 2005-08-11 Dexcom, Inc. Afinity domain for analyte sensor
US7651596B2 (en) * 2005-04-08 2010-01-26 Dexcom, Inc. Cellulosic-based interference domain for an analyte sensor
US7467003B2 (en) 2003-12-05 2008-12-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
WO2007120442A2 (fr) 2003-07-25 2007-10-25 Dexcom, Inc. Système d'électrode double pour capteur d'analyte continu
US7108778B2 (en) 2003-07-25 2006-09-19 Dexcom, Inc. Electrochemical sensors including electrode systems with increased oxygen generation
US7366556B2 (en) 2003-12-05 2008-04-29 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US7460898B2 (en) 2003-12-05 2008-12-02 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8423113B2 (en) 2003-07-25 2013-04-16 Dexcom, Inc. Systems and methods for processing sensor data
US9135402B2 (en) 2007-12-17 2015-09-15 Dexcom, Inc. Systems and methods for processing sensor data
US8845536B2 (en) 2003-08-01 2014-09-30 Dexcom, Inc. Transcutaneous analyte sensor
US8369919B2 (en) 2003-08-01 2013-02-05 Dexcom, Inc. Systems and methods for processing sensor data
US7591801B2 (en) 2004-02-26 2009-09-22 Dexcom, Inc. Integrated delivery device for continuous glucose sensor
US8060173B2 (en) * 2003-08-01 2011-11-15 Dexcom, Inc. System and methods for processing analyte sensor data
EP1502613A1 (fr) 2003-08-01 2005-02-02 Novo Nordisk A/S Appareil avec des moyens de rétraction de l'aiguille
US7774145B2 (en) 2003-08-01 2010-08-10 Dexcom, Inc. Transcutaneous analyte sensor
US8626257B2 (en) 2003-08-01 2014-01-07 Dexcom, Inc. Analyte sensor
US8886273B2 (en) 2003-08-01 2014-11-11 Dexcom, Inc. Analyte sensor
US8275437B2 (en) 2003-08-01 2012-09-25 Dexcom, Inc. Transcutaneous analyte sensor
US20050038331A1 (en) 2003-08-14 2005-02-17 Grayson Silaski Insertable sensor assembly having a coupled inductor communicative system
US7920906B2 (en) 2005-03-10 2011-04-05 Dexcom, Inc. System and methods for processing analyte sensor data for sensor calibration
US7497940B2 (en) 2003-09-02 2009-03-03 Koji Sode Glucose sensor and glucose level measuring apparatus
US20050090607A1 (en) 2003-10-28 2005-04-28 Dexcom, Inc. Silicone composition for biocompatible membrane
US7299082B2 (en) 2003-10-31 2007-11-20 Abbott Diabetes Care, Inc. Method of calibrating an analyte-measurement device, and associated methods, devices and systems
KR20060132434A (ko) 2003-11-06 2006-12-21 라이프스캔, 인코포레이티드 이벤트 통지 수단을 가지는 약물 전달 펜
US8615282B2 (en) 2004-07-13 2013-12-24 Dexcom, Inc. Analyte sensor
WO2005051170A2 (fr) * 2003-11-19 2005-06-09 Dexcom, Inc. Recepteur integre pour capteur d'analyte en continu
JP2007513650A (ja) 2003-11-20 2007-05-31 アンジオテック インターナショナル アーゲー 移植可能なセンサーおよび移植可能なポンプならびに瘢痕化抑制剤
US6850859B1 (en) 2003-12-03 2005-02-01 Watlow Electric Manufacturing Company Sensor drift compensation by lot
US20080197024A1 (en) 2003-12-05 2008-08-21 Dexcom, Inc. Analyte sensor
US8423114B2 (en) 2006-10-04 2013-04-16 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8364231B2 (en) * 2006-10-04 2013-01-29 Dexcom, Inc. Analyte sensor
US8425417B2 (en) 2003-12-05 2013-04-23 Dexcom, Inc. Integrated device for continuous in vivo analyte detection and simultaneous control of an infusion device
US20080200788A1 (en) 2006-10-04 2008-08-21 Dexcorn, Inc. Analyte sensor
US8532730B2 (en) 2006-10-04 2013-09-10 Dexcom, Inc. Analyte sensor
EP2239566B1 (fr) 2003-12-05 2014-04-23 DexCom, Inc. Techniques d'étalonnage pour capteur d'analytes en continu
US8364230B2 (en) 2006-10-04 2013-01-29 Dexcom, Inc. Analyte sensor
US8425416B2 (en) 2006-10-04 2013-04-23 Dexcom, Inc. Analyte sensor
US8287453B2 (en) 2003-12-05 2012-10-16 Dexcom, Inc. Analyte sensor
ATE474219T1 (de) 2003-12-08 2010-07-15 Dexcom Inc Systeme und verfahren zur verbesserung elektrochemischer analytsensoren
WO2005057175A2 (fr) * 2003-12-09 2005-06-23 Dexcom, Inc. Traitement de signal pour capteur continu d'analyte
US7637868B2 (en) 2004-01-12 2009-12-29 Dexcom, Inc. Composite material for implantable device
US8165651B2 (en) 2004-02-09 2012-04-24 Abbott Diabetes Care Inc. Analyte sensor, and associated system and method employing a catalytic agent
US7364592B2 (en) 2004-02-12 2008-04-29 Dexcom, Inc. Biointerface membrane with macro-and micro-architecture
EP1718198A4 (fr) 2004-02-17 2008-06-04 Therasense Inc Procede et systeme de communication de donnees dans un systeme de controle et de gestion de glucose en continu
US20060154642A1 (en) 2004-02-20 2006-07-13 Scannell Robert F Jr Medication & health, environmental, and security monitoring, alert, intervention, information and network system with associated and supporting apparatuses
US8808228B2 (en) 2004-02-26 2014-08-19 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
JP4705952B2 (ja) 2004-04-07 2011-06-22 カーディアック ペースメイカーズ， インコーポレイテッド 埋込み型医療装置におけるｒｆトランシーバ・デューティ・サイクルのシステムと方法
US8277713B2 (en) * 2004-05-03 2012-10-02 Dexcom, Inc. Implantable analyte sensor
AU2005244221B2 (en) 2004-05-03 2011-02-10 Ams Research Corporation Surgical implants and related methods
US20050245799A1 (en) * 2004-05-03 2005-11-03 Dexcom, Inc. Implantable analyte sensor
US7125382B2 (en) 2004-05-20 2006-10-24 Digital Angel Corporation Embedded bio-sensor system
US20070100222A1 (en) 2004-06-14 2007-05-03 Metronic Minimed, Inc. Analyte sensing apparatus for hospital use
US20070128682A1 (en) 2004-06-28 2007-06-07 Rosman Paul M Predictive treatment of dysglycemic excursions associated with diabetes mellitus
US20060001551A1 (en) * 2004-06-30 2006-01-05 Ulrich Kraft Analyte monitoring system with wireless alarm
US8224669B2 (en) * 2004-07-01 2012-07-17 Anchor Holdings, Inc. Chronic disease management system
US20060015020A1 (en) * 2004-07-06 2006-01-19 Dexcom, Inc. Systems and methods for manufacture of an analyte-measuring device including a membrane system
US20060020192A1 (en) * 2004-07-13 2006-01-26 Dexcom, Inc. Transcutaneous analyte sensor
WO2006127694A2 (fr) * 2004-07-13 2006-11-30 Dexcom, Inc. Detecteur d'analyte
US8452368B2 (en) 2004-07-13 2013-05-28 Dexcom, Inc. Transcutaneous analyte sensor
US7905833B2 (en) * 2004-07-13 2011-03-15 Dexcom, Inc. Transcutaneous analyte sensor
US8565848B2 (en) 2004-07-13 2013-10-22 Dexcom, Inc. Transcutaneous analyte sensor
US7783333B2 (en) 2004-07-13 2010-08-24 Dexcom, Inc. Transcutaneous medical device with variable stiffness
US20080242961A1 (en) 2004-07-13 2008-10-02 Dexcom, Inc. Transcutaneous analyte sensor
WO2006037109A2 (fr) 2004-09-27 2006-04-06 Deka Products Limited Partnership Ameliorations relatives a des ensembles d'infusion
DE102004048864A1 (de) 2004-10-07 2006-04-13 Roche Diagnostics Gmbh Analytisches Testelement mit drahtloser Datenübertragung
US8224414B2 (en) 2004-10-28 2012-07-17 Echo Therapeutics, Inc. System and method for analyte sampling and analysis with hydrogel
US20060095021A1 (en) 2004-11-02 2006-05-04 Casas-Bejar Jesus W Introduction of agent with medical device
CA2586927A1 (fr) 2004-11-09 2006-05-18 Angiotech Biocoatings Corp. Revetement d'aiguille antimicrobien pour perfusion prolongee
US20060173712A1 (en) 2004-11-12 2006-08-03 Dirk Joubert Portable medical information system
US7697967B2 (en) 2005-12-28 2010-04-13 Abbott Diabetes Care Inc. Method and apparatus for providing analyte sensor insertion
US8029441B2 (en) 2006-02-28 2011-10-04 Abbott Diabetes Care Inc. Analyte sensor transmitter unit configuration for a data monitoring and management system
US7547281B2 (en) * 2005-02-01 2009-06-16 Medtronic Minimed, Inc. Algorithm sensor augmented bolus estimator for semi-closed loop infusion system
US9022980B2 (en) 2005-02-01 2015-05-05 Kaleo, Inc. Medical injector simulation device
US20060178633A1 (en) 2005-02-03 2006-08-10 Insulet Corporation Chassis for fluid delivery device
WO2006094513A2 (fr) 2005-03-09 2006-09-14 Coloplast A/S Dispositif adhesif tridimensionnel auquel est integre un systeme micro-electronique
US20090076360A1 (en) 2007-09-13 2009-03-19 Dexcom, Inc. Transcutaneous analyte sensor
US20060224141A1 (en) 2005-03-21 2006-10-05 Abbott Diabetes Care, Inc. Method and system for providing integrated medication infusion and analyte monitoring system
US7641649B2 (en) * 2005-05-06 2010-01-05 Medtronic Minimed, Inc. Reservoir support and method for infusion device
US7670288B2 (en) 2005-06-08 2010-03-02 Sher Philip M Fluctuating blood glucose notification threshold profiles and methods of use
US8251904B2 (en) 2005-06-09 2012-08-28 Roche Diagnostics Operations, Inc. Device and method for insulin dosing
US20060293577A1 (en) 2005-06-23 2006-12-28 Morrison Andrew E Glucose monitoring kit
US20070060869A1 (en) * 2005-08-16 2007-03-15 Tolle Mike C V Controller device for an infusion pump
US20070060870A1 (en) * 2005-08-16 2007-03-15 Tolle Mike Charles V Controller device for an infusion pump
US20070093786A1 (en) 2005-08-16 2007-04-26 Medtronic Minimed, Inc. Watch controller for a medical device
US7713240B2 (en) * 2005-09-13 2010-05-11 Medtronic Minimed, Inc. Modular external infusion device
EP1774932B1 (fr) 2005-10-11 2015-08-26 ConvaTec Technologies Inc. Accouplement d'ostomie
US7963917B2 (en) 2005-12-05 2011-06-21 Echo Therapeutics, Inc. System and method for continuous non-invasive glucose monitoring
US7736310B2 (en) 2006-01-30 2010-06-15 Abbott Diabetes Care Inc. On-body medical device securement
CN104162200B (zh) 2006-02-09 2018-03-27 德卡产品有限公司 外围系统
WO2007093981A2 (fr) * 2006-02-15 2007-08-23 Medingo Ltd. Systèmes et procédés de détection d'un analyte et d'administration d'un fluide thérapeutique
EP2407094B2 (fr) 2006-02-22 2022-05-11 DexCom, Inc. Capteur d'analytes
US7981034B2 (en) 2006-02-28 2011-07-19 Abbott Diabetes Care Inc. Smart messages and alerts for an infusion delivery and management system
US7885698B2 (en) 2006-02-28 2011-02-08 Abbott Diabetes Care Inc. Method and system for providing continuous calibration of implantable analyte sensors
EP1991110B1 (fr) * 2006-03-09 2018-11-07 DexCom, Inc. Systèmes et procédés de traitement de données de capteur de substance à analyser
US8770482B2 (en) 2006-04-26 2014-07-08 Roche Diagnostics Operations, Inc. Apparatus and method to administer and manage an intelligent base unit for a handheld medical device
WO2007149533A2 (fr) 2006-06-19 2007-12-27 Dose Safety Système, procédé et article pour commander la distribution de l'insuline
US20080004601A1 (en) * 2006-06-28 2008-01-03 Abbott Diabetes Care, Inc. Analyte Monitoring and Therapy Management System and Methods Therefor
US9119582B2 (en) 2006-06-30 2015-09-01 Abbott Diabetes Care, Inc. Integrated analyte sensor and infusion device and methods therefor
US20080018480A1 (en) * 2006-07-20 2008-01-24 Sham John C K Remote body temperature monitoring device
US7769345B2 (en) 2006-09-29 2010-08-03 Sony Ericsson Mobile Communications Ab Device and method for guiding a user to a communication position
US7831287B2 (en) 2006-10-04 2010-11-09 Dexcom, Inc. Dual electrode system for a continuous analyte sensor
US8562528B2 (en) 2006-10-04 2013-10-22 Dexcom, Inc. Analyte sensor
US8449464B2 (en) 2006-10-04 2013-05-28 Dexcom, Inc. Analyte sensor
US8447376B2 (en) 2006-10-04 2013-05-21 Dexcom, Inc. Analyte sensor
US8275438B2 (en) 2006-10-04 2012-09-25 Dexcom, Inc. Analyte sensor
US8478377B2 (en) 2006-10-04 2013-07-02 Dexcom, Inc. Analyte sensor
US8298142B2 (en) 2006-10-04 2012-10-30 Dexcom, Inc. Analyte sensor
US7946985B2 (en) 2006-12-29 2011-05-24 Medtronic Minimed, Inc. Method and system for providing sensor redundancy
US8323250B2 (en) 2007-04-30 2012-12-04 Medtronic Minimed, Inc. Adhesive patch systems and methods
US20080306434A1 (en) 2007-06-08 2008-12-11 Dexcom, Inc. Integrated medicament delivery device for use with continuous analyte sensor
US9968742B2 (en) * 2007-08-29 2018-05-15 Medtronic Minimed, Inc. Combined sensor and infusion set using separated sites
US8417312B2 (en) 2007-10-25 2013-04-09 Dexcom, Inc. Systems and methods for processing sensor data
US9839395B2 (en) 2007-12-17 2017-12-12 Dexcom, Inc. Systems and methods for processing sensor data
US20090163855A1 (en) * 2007-12-24 2009-06-25 Medtronic Minimed, Inc. Infusion system with adaptive user interface
US20090299155A1 (en) 2008-01-30 2009-12-03 Dexcom, Inc. Continuous cardiac marker sensor system
US20090299156A1 (en) 2008-02-20 2009-12-03 Dexcom, Inc. Continuous medicament sensor system for in vivo use
US9143569B2 (en) 2008-02-21 2015-09-22 Dexcom, Inc. Systems and methods for processing, transmitting and displaying sensor data
US20090242399A1 (en) 2008-03-25 2009-10-01 Dexcom, Inc. Analyte sensor
US8396528B2 (en) 2008-03-25 2013-03-12 Dexcom, Inc. Analyte sensor
CN102047101A (zh) 2008-03-28 2011-05-04 德克斯康公司 用于连续的分析物传感器的聚合物膜
US8560039B2 (en) 2008-09-19 2013-10-15 Dexcom, Inc. Particle-containing membrane and particulate electrode for analyte sensors

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2008005780A3 *

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US9119582B2 (en) 2015-09-01
US20240033429A1 (en) 2024-02-01
WO2008005780A2 (fr) 2008-01-10
US20090069650A1 (en) 2009-03-12
US20160022906A1 (en) 2016-01-28
US8512244B2 (en) 2013-08-20
US20190151541A1 (en) 2019-05-23
US20080004515A1 (en) 2008-01-03
US10220145B2 (en) 2019-03-05
US11918782B2 (en) 2024-03-05
CA2656581A1 (fr) 2008-01-10

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