EP1993432A1 - Dispositif d'enregistrement photographique du fond de l'il - Google Patents

Dispositif d'enregistrement photographique du fond de l'il

Info

Publication number
EP1993432A1
EP1993432A1 EP06705387A EP06705387A EP1993432A1 EP 1993432 A1 EP1993432 A1 EP 1993432A1 EP 06705387 A EP06705387 A EP 06705387A EP 06705387 A EP06705387 A EP 06705387A EP 1993432 A1 EP1993432 A1 EP 1993432A1
Authority
EP
European Patent Office
Prior art keywords
fundus
frequency bands
image
images
light
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP06705387A
Other languages
German (de)
English (en)
Inventor
Yves Robert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
OPHTHAMETRICS AG
Original Assignee
OPHTHAMETRICS AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by OPHTHAMETRICS AG filed Critical OPHTHAMETRICS AG
Publication of EP1993432A1 publication Critical patent/EP1993432A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/14—Arrangements specially adapted for eye photography
    • A61B3/15—Arrangements specially adapted for eye photography with means for aligning, spacing or blocking spurious reflection ; with means for relaxing
    • A61B3/156—Arrangements specially adapted for eye photography with means for aligning, spacing or blocking spurious reflection ; with means for relaxing for blocking
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
    • A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
    • A61B3/117—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for examining the anterior chamber or the anterior chamber angle, e.g. gonioscopes
    • A61B3/1173—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for examining the anterior chamber or the anterior chamber angle, e.g. gonioscopes for examining the eye lens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14555—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases specially adapted for the eye fundus

Definitions

  • the invention relates to a device for photographing the ocular fundus (Fundus oculi) according to the preamble of patent claim 1.
  • the invention aims to remedy this situation.
  • the invention has for its object to provide a device (fundus camera), which allows, with low illuminance and without medical dilation of the pupil of the patient, on the one hand color images of high quality and on the other hand to record spectrally resolved images.
  • the device according to the invention should make it possible to determine different blood values, in particular the concentration of hemoglobin, as well as the turbidity of the eye lens.
  • the invention achieves the stated object with a device having the features of claim 1.
  • the device according to the invention is characterized in that narrow-band light (preferably low intensity) is used to illuminate the fundus in several, but at least 2 frequency bands, the light of the different frequency bands being applied successively in time and an image of the fundus being stored by each spectral range. Thanks to the low momentary light intensity, the pupillary reflex is largely avoided. Since the patient is not blinded, the measurement can be repeated briefly in succession. It is a feature of the present invention that the spectral splitting already takes place during the illumination of the fundus and that the individual frequency bands are applied separately in time. This makes it possible to keep the momentary intensity of the light low.
  • narrow-band light preferably low intensity
  • the color of the light passes through from one end of the visible spectrum to the other and thereby registers the fundus images of the individual frequency bands, these can subsequently be combined to form a color image which is practically very close to a recording with white light.
  • a spectral distribution of the light is necessary and already given by the illumination method in the present invention.
  • the blue light is advantageous for determining lens opacity: in this procedure, the contrast between fovea and papilla is evaluated, which works best in the blue region.
  • a black and white CCD camera can be used.
  • black and white CCDs are much more sensitive than color CCDs.
  • the device In order to carry out fundus recordings on a non-dilated pupil with the device according to the invention, it should be functional with a pupil diameter of preferably not more than 3-4 mm. Relative movements of the eye to the image-taking camera limit the usable aperture to about 2 mm. Through this opening, both the lighting and the image must be made. Due to internal reflexes, especially on the cornea and the eye lens itself, the illumination and imaging beam path must be spatially separated. For this purpose, the available aperture is divided concentrically into an outer ring for illumination and an inner circle for imaging. The imaging circle should be as large as possible, as this maximizes the diffraction-limited resolution and the light output. On the other hand, the concentric lighting ring should not be chosen too thin, otherwise, in order to couple a certain energy, the light intensity is too large. A preferred choice is provide the same illumination and imaging surfaces, possibly a slightly larger central imaging surface.
  • the image capture camera can be a black and white CCD camera.
  • the fundus camera has a positioning device with the help of which the optical axis of the eye and the image-recording camera and the distance imaging optics (2; 3; 14; 15; 16) - Cornea can be set exactly and reproducibly.
  • This process is described in US Pat. No. 5,474,451 (Robert et al.).
  • the reproducibility of the positioning is important in order, on the one hand, to always be able to set the unavoidable reflections and losses due to lens opacity when measuring absolute blood values.
  • the reproducibility for the time-sequential recording of fundus images of different spectral regions is important, so that as identical as possible sections are sharply reproduced, so that they can subsequently be compiled with minimal effort to form a color image.
  • the optical design of the fundus camera is such that under the mentioned boundary conditions, the light output is as large as possible.
  • the frequency bands can each have a bandwidth of 5 to 50 nm, preferably 10 to 30 nm.
  • the light directed to the fundus may be in the visible range (preferably with a wavelength between 400-800 nm) or in the infrared range
  • the images generated can be stored in digitized form.
  • the time intervals between the individual frequency bands should expediently be kept as small as possible, preferably less than 100 ms and typically less than 20 ms.
  • the following method for photographing the ocular fundus can be carried out: a) temporally successive illumination of the fundus with spectrally limited light comprising at least two different frequency bands, b) photographic recordings of the temporally successive with different frequency bands illuminated fundus by means of a photographic image-taking camera.
  • the time-sequentially obtained, photographic images of the fundus to a total image (color image) are superposed.
  • the total power radiated into the eye is 30 to 100 ⁇ W.
  • the exposure time of the fundus in each of the individual frequency bands is preferably in the range of 10 - 30 ms.
  • Fig. 1 the schematic layout of an inventive device
  • the inventive device consists essentially of an illumination source (1), an imaging optics and a lighting optics.
  • the two beam paths are coupled by a first beam splitter 2.
  • the first beam splitter 2 is selected such that the light reflected from the fundus falls to about 95% on the image-taking camera 3. Accordingly, only about 5% of the illumination energy comes to the eye, but this is not a problem because there are enough strong sources of illumination available. This in a straight line through the first Beam splitter 2 reaching illumination light is almost completely absorbed in a beam absorber 4.
  • Positioning beam 6 according to US Patent No. 5474451 (Robert) coupled. Furthermore, a light point for guiding the eye of the patient is present via a second beam splitter 7.
  • the necessary light is e.g. from a cold light source via a fiber bundle coupled (top of Fig. 1).
  • a fiber bundle coupled top of Fig. 1.
  • an IR LED can be used to generate
  • Illumination optics (1; 2; 4,8; 9; 10):
  • a tunable or mechanically rapidly exchangeable interference filter 8 generates narrow-band light with a bandwidth of typically 10 to 30 nm.
  • the illumination beam lens 10 ensures a uniform illumination of the
  • the first beam splitter 2 reflects about 5% of the light in the direction of the eye 20, the transmitted part is rendered harmless by the beam absorber 4.
  • the second beam splitter 7 below the illumination source 1 in the form of a
  • Lighting fiber bundle serves to show a small point of light. This is generated by a LED 11 with subsequent pinhole 17. The patient is fixated
  • the IR illumination 12 for patient positioning generated together with the
  • Conveying lens 13 and the annular mirror 5 is a converging light beam from the
  • the annular mirror 5 is shown in the form of an elliptical mirror with an elliptical hole in the middle.
  • the major axes of the ellipses are chosen so that the mirror in a 45 ° projection as a circle with a circular
  • the fundus is imaged by an aspherical ophthalmoscopic lens 16.
  • the light reflected from the fundus passes through the first beam splitter 2 through 95% is projected enlarged by the first imaging lens 14 and the second imaging lens 15 on the CCD chip.
  • the image pickup camera 3 used is a CCD camera, which has a
  • Interface is connected to a PC, so that the captured image can be digitized, stored and processed further.
  • the beam path is shielded from foreign and stray light by a blackened housing.
  • An x, y cross table makes it possible to finely adjust the device with respect to the patient's eye, wherein the adjustment can also be done automatically either by hand or by evaluating the above-mentioned positioning beam 6 and by means of suitable actuators.

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Eye Examination Apparatus (AREA)

Abstract

L'invention concerne un dispositif d'enregistrement photographique du fond de l'oel. Ce dispositif comprend A) une source d'éclairage (1) ; B) une optique d'éclairage (1 ; 2 ; 4 ; 8 ; 9 ; 10) capable de générer de la lumière dans au moins deux bandes de fréquence différentes et de la diriger successivement dans le temps sur le fond de l'oel ; C) une optique d'imagerie (2 ; 3 ; 14 ; 15 ; 16) capable de générer successivement dans le temps des images du fond de l'oel éclairé avec des bandes de fréquence différentes ; et D) un appareil de prise de vues photographiques (3) capable d'enregistrer les images générées. Avec une faible intensité d'éclairage et sans dilatation médicamenteuse de la pupille du patient, ce dispositif permet d'enregistrer d'une part des images en couleurs de grande qualité et d'autre part des images à résolution spectrale. En outre, le dispositif permet de déterminer différents paramètres sanguins, en particulier la concentration en hémoglobine, ainsi que l'opacité du cristallin.
EP06705387A 2006-03-13 2006-03-13 Dispositif d'enregistrement photographique du fond de l'il Withdrawn EP1993432A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CH2006/000147 WO2007104165A1 (fr) 2006-03-13 2006-03-13 Dispositif d'enregistrement photographique du fond de l'œil

Publications (1)

Publication Number Publication Date
EP1993432A1 true EP1993432A1 (fr) 2008-11-26

Family

ID=37814493

Family Applications (1)

Application Number Title Priority Date Filing Date
EP06705387A Withdrawn EP1993432A1 (fr) 2006-03-13 2006-03-13 Dispositif d'enregistrement photographique du fond de l'il

Country Status (3)

Country Link
US (1) US20090079936A1 (fr)
EP (1) EP1993432A1 (fr)
WO (1) WO2007104165A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009083419A1 (fr) * 2007-12-30 2009-07-09 Ophthametrics Ag Dispositif pour photographier avec peu de reflets le fond de l'œil, avec une tolérance améliorée vis-à-vis des décalages latéraux
US9168173B2 (en) * 2008-04-04 2015-10-27 Truevision Systems, Inc. Apparatus and methods for performing enhanced visually directed procedures under low ambient light conditions
CH706603B1 (de) 2011-08-03 2016-08-31 Ophthametrics Ag Hrm Man & Treuhand Ag Aufnahmevorrichtung zur Aufnahme einer Netzhaut eines Auges sowie Aufnahmeverfahren.
US10582853B2 (en) 2018-03-13 2020-03-10 Welch Allyn, Inc. Selective illumination fundus imaging
DE102021117734A1 (de) 2021-07-09 2023-01-12 Karl Leibinger Medizintechnik Gmbh & Co. Kg Beleuchtungsanordnung

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH688304A5 (de) * 1993-01-28 1997-07-31 Yves Prof Dr Robert Ophthalmologisches Geraet.
US5474451A (en) 1994-02-02 1995-12-12 Regents Of The University Of Minnesota Dental water and air purification equipment
US6142629A (en) * 1998-08-30 2000-11-07 Applied Spectral Imaging Ltd. Spectral imaging using illumination of preselected spectral content
GB2375679A (en) * 2001-04-09 2002-11-20 Patrick Kerr Retinal function camera using plural light wavelengths to produce a retinal function image showing haemoglobin oxygenation.
US7001020B2 (en) * 2001-08-02 2006-02-21 Daphne Instruments, Inc. Complete autorefractor system in an ultra-compact package
WO2003061460A2 (fr) * 2002-01-18 2003-07-31 Universiy Of Iowa Research Foundation Dispositif et procede d'imagerie optique d'une fonction retinienne
DE102004020663A1 (de) * 2004-04-24 2005-11-10 Carl Zeiss Meditec Ag Einrichtung zur Beleuchtung organischer Objekte

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2007104165A1 *

Also Published As

Publication number Publication date
US20090079936A1 (en) 2009-03-26
WO2007104165A1 (fr) 2007-09-20

Similar Documents

Publication Publication Date Title
DE112013006234B4 (de) Ophthalmologische Vorrichtung
DE60121123T2 (de) Verfahren und vorrichtung zur messung von refraktiven fehlern eines auges
DE60204678T2 (de) Netzhautfunktionskamera
DE69533518T2 (de) Anordnung zur abbildung des augeninneren
DE102015203443B4 (de) Ophthalmologische Bildgebungsvorrichtung und optische Einheit, die an dieser befestigbar ist
EP1327412B1 (fr) Dispositif pour illuminer la lentille de l'oeil humain
DE60309185T2 (de) Verfahren und anordnung zur durchführung von messungen der topographie einer oberfläche durch thermische emission von einer oberfläche
DE102006061933A1 (de) Optisches System für eine Funduskamera
DE102005032501A1 (de) Vorrichtung zur Untersuchung vorderer und hinterer Augenabschnitte
WO2012059236A1 (fr) Caméra rétinienne comprenant une partie pupillaire en forme de bande et procédé pour l'enregistrement sans artefact de prises de vue rétiniennes à haute résolution
WO2002053020A2 (fr) Dispositif et procede d'imagerie, de stimulation, de mesure et de therapie, en particulier de l'oeil
WO2008067922A1 (fr) Procédé de production d'images de haute qualité des parties avant et/ou arrière de l'oeil
EP1993432A1 (fr) Dispositif d'enregistrement photographique du fond de l'il
DE4240583A1 (en) Apparatus for examination and photography of corneal endothelium - has three optical systems for illuminating cornea and processing reflections for image forming and automatic photography.
DE10307741A1 (de) Anordnung zur Bildfeldverbesserung bei ophthalmologischen Geräten
EP2114237B1 (fr) Agencement d'appareils ophtalmologiques visant a l'amelioration des images d'observation
EP0136440B1 (fr) Appareil ophthalmique et dispositif de mesure pour l'examen du fond de l'oeil
DE60204178T2 (de) Aberrationsfreie Abbildung des Augenhintergrundes
DE102005003440A1 (de) Fokussiervorrichtung für ophthalmologische Geräte, insbesondere Funduskameras und Verfahren zu dessen Verwendung
DE102007047460A1 (de) Vorrichtung und Verfahren zur Untersuchung des Augenhintergrundes, inbesondere der Photorezeptoren
WO2012159752A2 (fr) Système de microscopie pour examen ophtalmologique et procédé permettant de faire fonctionner un système de microscopie
WO2009059737A1 (fr) Dispositif et procédé permettant une détermination automatique de l'intensité d'une cataracte, et appareil ophtalmologique et procédé de commande correspondants
DE60221651T2 (de) Kornea-Topograph mit integrierter Pupillentest-Vorrichtung
WO2014125063A1 (fr) Ensemble et dispositif d'exposition automatique de prises de vue du fond de l'œil
WO2015185682A2 (fr) Module topographique pour appareils ophtalmologiques avec système de kératométrie en fonction de la distance et son procédé d'utilisation

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20080912

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20111001