EP1955964B1 - Durchlöcherbarer Verschluss - Google Patents

Durchlöcherbarer Verschluss Download PDF

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Publication number
EP1955964B1
EP1955964B1 EP20080250281 EP08250281A EP1955964B1 EP 1955964 B1 EP1955964 B1 EP 1955964B1 EP 20080250281 EP20080250281 EP 20080250281 EP 08250281 A EP08250281 A EP 08250281A EP 1955964 B1 EP1955964 B1 EP 1955964B1
Authority
EP
European Patent Office
Prior art keywords
closure
openings
sealing element
perforable
opening
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
EP20080250281
Other languages
English (en)
French (fr)
Other versions
EP1955964A1 (de
Inventor
Claude Benoit-Gonin
Philippe Bardet
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Obrist Closures Switzerland GmbH
Original Assignee
Obrist Closures Switzerland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Obrist Closures Switzerland GmbH filed Critical Obrist Closures Switzerland GmbH
Priority to PL08250281T priority Critical patent/PL1955964T3/pl
Publication of EP1955964A1 publication Critical patent/EP1955964A1/de
Application granted granted Critical
Publication of EP1955964B1 publication Critical patent/EP1955964B1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/002—Closures to be pierced by an extracting-device for the contents and fixed on the container by separate retaining means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1406—Septums, pierceable membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D51/00—Closures not otherwise provided for
    • B65D51/18—Arrangements of closures with protective outer cap-like covers or of two or more co-operating closures
    • B65D51/20—Caps, lids, or covers co-operating with an inner closure arranged to be opened by piercing, cutting, or tearing
    • B65D51/22—Caps, lids, or covers co-operating with an inner closure arranged to be opened by piercing, cutting, or tearing having means for piercing, cutting, or tearing the inner closure
    • B65D51/221—Caps, lids, or covers co-operating with an inner closure arranged to be opened by piercing, cutting, or tearing having means for piercing, cutting, or tearing the inner closure a major part of the inner closure being left inside the container after the opening
    • B65D51/222—Caps, lids, or covers co-operating with an inner closure arranged to be opened by piercing, cutting, or tearing having means for piercing, cutting, or tearing the inner closure a major part of the inner closure being left inside the container after the opening the piercing or cutting means being integral with, or fixedly attached to, the outer closure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/2013—Piercing means having two piercing ends
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents

Definitions

  • the present invention relates generally to a closure and particularly to a perforable closure for use in conjunction with perforating elements such as syringes, needles and the like.
  • closures are used, for example, in conjunction with containers for medicines, in which the contents must be kept sterile.
  • Perforating elements can be introduced into the container through the closure.
  • the closures are self-sealing to punctures from perforating elements.
  • closures examples include FR2598137 , EP0364783 , US2135386 and EP1392569 .
  • the present invention seeks to address certain problems with known perforable closures.
  • WO 03/013972A1 discloses a closure cap for a transfusion bottle according to the preamble of claim 1, which includes a rubber-type sealing part adapted to fit upon the neck of a bottle, covered by a closure cap and a top cap. Areas of the sealing part are exposed in areas of penetration provided in the closure cap. The top cap is axially spaced from the closure cap.
  • EP 1 547 429 A2 also describes a closure for a transfusion container which includes a sealing part and a cover portion.
  • the cover portion includes regions in which expose the sealing part for puncture.
  • a perforable closure comprising: a body with two or more perforable openings configured to receive different perforating elements and an internal sealing element which is inseparably welded to the body, characterised in that the internal sealing element extends across the interior side of each opening and does not extend into the openings.
  • the closure body has at least two openings.
  • the openings are adapted to receive different perforating elements.
  • the sealing element is inseparably welded to the body.
  • the closure may be formed by bi-injection moulding with the sealing element being injected into a pre-formed body.
  • the sealing element is positioned in the body to extend across the interior side of each opening. In other words, the sealing element does not extend into the openings but rather seals around the internal periphery thereof.
  • One or at least one of the opening/s may comprise a chimney for limiting entry of a perforating element.
  • the perforating element can then be optimally positioned to be able to extract container contents.
  • the or at least one of the opening/s may be provided with a removable cover.
  • the sealing element of the closure may be a different colour to the closure body. Accordingly the sealing element can be distinguished from the body to facilitate puncture.
  • the closure may comprise o plurality of removable covers, in which the covers include means for indicating which particular opening they cover. In this way the correct opening can easily be selected and uncovered whilst leaving other openings covered.
  • the closure may further comprise an outer closure member.
  • the outer closure may comprise a perforating element. When the outer closure is applied the perforating element may puncture the sealing element of a respective opening.
  • the outer closure member and the closure may include angular orientation means. Accordingly the components can be correctly positioned with respect to each other for use.
  • the present invention also provides the combination of a container and a perforable closure as described herein.
  • FIG. 1 and 2 there is shown a perforable closure generally indicated 10 and attached to a container 15. Also shown are two cover elements 20, 21 which are shown removed in Figure 1 and in position in Figure 2 . Further, a puncture assembly is shown and comprises a first needle member 25 and an outer closure 30 which incorporates a second needle member 31.
  • the closure 10 comprises a generally cylindrical body 40 having a radially outwardly extending flange 41 at one end thereof. This end of the body is adapted to receive the neck 16 of the container 15.
  • the container neck 16 includes a radially outwardly extending transfer bead 17 against which the closure flange 41 abuts as shown in Figure 4 .
  • the closure 10 is secured to the container neck 16 by any convenient means, which in this embodiment comprise as snap bead arrangement (not shown).
  • the end of the body 40 opposite the flange 41 defines two openings 50, 55.
  • the opening 50 is defined by o cylindrical chimney 51.
  • the chimney 51 is flanked by two upstanding rectangular fins 51, 52.
  • the opening 55 is defined in part by an extension of the body 40 from the top end of which extends a semi-circular plate 56 incorporating the ellipsoidal opening 55.
  • the plate 56 continues with a downwardly inclined step 57 which extends to the same level as the base of the chimney 51.
  • the exterior of the openings. 50, 55 terminate at the same level but the interior of the opening 50 commences at a level closer to the flange 41 than the opening 55.
  • a sealing element 60 shown best in Figure 3 is positioned within the interior of the closure body 40 as best shown in Figure 4 .
  • the sealing element is generally circular but with a step 61 separating it into a generally semi-circular lower portion 62 and a generally semi-circular upper portion 63.
  • the portions 62. 63 are generally planar.
  • the stepped configuration of the sealing element 60 allows it to mirror the contours of the end of the body 40 incorporating the openings 50, 55. Accordingly, as shown in Figure 4 the sealing element 60 lies across the interior sides of the openings, 50, 55, but does not protrude into them.
  • the sealing element 60 is formed into the closure body 40 by a sequential moulding process in which the body 40 is first formed and then used as port of the mould for injection of the sealing element 60. In this way the sealing element 60 becomes inseparably welded to the interior of the closure body 40. in other embodiments the sealing element 60 may be formed completely separately of the closure body 40 and secured into position by any convenient means such as adhesion or welding.
  • the exterior of the body 40 includes an axial rib 42 the purpose of which will be described in more detail below.
  • the covers 20, 21 are shown in position over the exterior sides of the openings 50, 55 respectively.
  • the covers 20, 21 are formed from aluminium foil and ore heat-sealed onto the openings 50. 55.
  • the opening 20 has a circular depression 22 corresponding to the circular opening 50 and the cover 21 includes an ellipsoidal depression 23 corresponding to the ellipsoidal opening 55. Accordingly, with the covers 20. 21 in position as shown in Figures 2 and 4 it is easy to distinguish between the openings 50. 55 positioned beneath the covers 20, 21.
  • the closure 10 is shown positioned on the container 15 and with both covers 20,21 removed. Also shown is the outer closure 30 including the needle 31.
  • the outer closure 30 comprises a main cylindrical body 32 and a secondary cylindrical body 33 which has a main axis offset from that of the main body 32.
  • the secondary cylindrical body 33 is open at one end and partially dosed at the other by the top plate 32a of the cylindrical body 32 with the exception of an orifice 32b through which the needle 31 passes and is held securely.
  • the main body 32 also comprises an axial channel 34 which is sized and positioned to receive the rib 42 on the closure body 10 when the outer closure 30 is fitted on as shown in Figure 5 .
  • the rib 42 and the channel 34 co-operate to position the outer closure 30 in a particular angular orientation with respect to the closure 10 and to hold it in that position as shown in Figure 5 .
  • the needle 31 With the needle 31 held firmly in place, when the outer closure 30 is applied to the closure 10 the needle 31 punctures the sealing element 60 through the opening 55 and then punctures the container neck cover 18.
  • the piercing element 25 includes an elongate shaft 26 terminating in an aperture 27.
  • the opposite end of the shaft 26 terminates with a collar 28.
  • the collar 28 acts as a dep stop so that when the element 25 is inserted through the opening 50 and through the cover 18 the collar 28 abuts against the exterior end of the chimney 51. Accordingly, the aperture 27 can be precisely positioned within the interior of the container 15.
  • FIG. 9 and 10 there is shown a closure 110 formed according to an alternative embodiment.
  • the closure 110 is very similar to the closure 10 shown in Figures 1 to 8 .
  • the major difference is the form of the sealing element 160, which in the embodiment is not a complete circle but rather a generally rectangular strip.
  • the sealing element 160 is so-formed to be accommodated within the upper region of the closure body 140, which in this embodiment includes two lateral steps 170, 171.
  • the sealing element 160 does not therefore extend over the entire interior surface of the upper end of the body 140.
  • FIG. 11 and 12 there is shown a closure 210 formed according to an alternative embodiment.
  • the closure 210 is very similar to the closure 110 shown in Figures 9 and 10 .
  • the fins 152, 153 which flank the chimney 151 are not parallel but rather diverge towards the periphery of the closure.
  • the lower part 262 of the sealing element 260 is fan-shaped to correspond with the region defined by the fins 251, 252.
  • FIG. 13 there is shown a closure 310 formed according to an alternative embodiment.
  • the closure is similar to the closures shown in Figures 1 to 11 .
  • the openings are provided at either end of a figure-of-eight chimney 265 projecting from a top deck 270, as shown best in Figures 14 and 15 .
  • the openings 250, 255 are covered, by respective disc-shape foil covers 220, 221 each having a respective pull tab 220a, 221a.
  • the covers 220, 221 are positioned over the openings 250, 255 as shown in Figure 14 and then welded into position.
  • the opening 250 is provided in the closure 210.
  • only one perforable opening is provided.
  • Embodiments with three, four and more openings may also be provided.

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Closures For Containers (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Ignition Installations For Internal Combustion Engines (AREA)
  • Glass Compositions (AREA)
  • Cable Accessories (AREA)

Claims (10)

  1. Durchstechbarer Verschluss (10; 110; 210; 310), der aufweist: einen Körper (40; 140) mit zwei oder mehr durchstechbaren Öffnungen (50, 55; 250; 255), die gestaltet sind, um verschiedene Durchstechelemente aufzunehmen, und
    ein inneres Dichtungselement (60; 160; 260), das untrennbar mit dem Körper verschweißt ist,
    dadurch gekennzeichnet, dass das innere Dichtungselement sich über die innenliegende Seite einer jeden Öffnung erstreckt und nicht in die Öffnungen ragt.
  2. Verschluss gemäß Anspruch 1, bei dem sich zwei oder mehrere durchstechbare Öffnungen (50,55; 250, 255) in Form und Abmessung unterscheiden.
  3. Verschluss gemäß einem der vorhergehenden Ansprüche, in dem wenigstens eine der Öffnungen einen Zylinder (51; 265) aufweist, um den Eintritt eines Durchstechelements zu begrenzen.
  4. Verschluss gemäß einem der vorhergehenden Ansprüche, bei dem wenigstens eine der Öffnungen mit einer entfernbaren Abdeckung (20, 21; 220, 221) versehen ist.
  5. Verschluss gemäß einem der vorhergehenden Ansprüche, wobei das Dichtungselement (60; 160; 260) sich von dem Verschlusskörper (40; 140) farblich unterscheidet.
  6. Verschluss gemäß einem der vorhergehenden Ansprüche, wobei der Verschluss eine Vielzahl an Öffnungen aufweist, die mit einer Vielzahl an entfernbaren Abdeckungen versehen sind, wobei die Abdeckungen Mittel zur Anzeige enthalten, welche spezielle Öffnung sie abdecken.
  7. Verschluss gemäß einem der vorhergehenden Ansprüche, der weiterhin ein äußeres Verschlusselement (30) aufweist.
  8. Verschluss gemäß Anspruch 7, wobei der äußere Verschluss (30) ein Durchstechelement (31) aufweist.
  9. Verschluss gemäß Anspruch 7 oder 8, wobei das äußere Verschlusselement und der Verschluss winkelige Ausrichtungsmittel (42, 34) enthalten.
  10. Kombination aus einem Behältnis und einem durchstechbaren Verschluss gemäß einem der vorhergehenden Ansprüche.
EP20080250281 2007-01-24 2008-01-23 Durchlöcherbarer Verschluss Active EP1955964B1 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL08250281T PL1955964T3 (pl) 2007-01-24 2008-01-23 Przebijane zamknięcie

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB0701326A GB0701326D0 (en) 2007-01-24 2007-01-24 A perforable closure

Publications (2)

Publication Number Publication Date
EP1955964A1 EP1955964A1 (de) 2008-08-13
EP1955964B1 true EP1955964B1 (de) 2010-11-17

Family

ID=37872682

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20080250281 Active EP1955964B1 (de) 2007-01-24 2008-01-23 Durchlöcherbarer Verschluss

Country Status (6)

Country Link
EP (1) EP1955964B1 (de)
AT (1) ATE488446T1 (de)
DE (1) DE602008003461D1 (de)
ES (1) ES2355638T3 (de)
GB (1) GB0701326D0 (de)
PL (1) PL1955964T3 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102014226900A1 (de) * 2014-12-23 2016-06-23 B. Braun Melsungen Ag Verschlusskappensystem für ein medizinisches Fluidspeicherbehältnis

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102017000048A1 (de) * 2017-01-05 2018-07-05 Kocher-Plastik Maschinenbau Gmbh Behälter
DE102020208146A1 (de) 2020-06-30 2021-12-30 B. Braun Melsungen Aktiengesellschaft Kappe für medizinischen Fluidbehälter, Ansatzteil für Kappe, System umfassend Kappe und Ansatzteil, medizinischer Fluidbehälter, System umfassend medizinischen Fluidbehälter und Ansatzteil, Verfahren zum Herstellen eines Fluidbehälters

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2135386A (en) 1937-06-18 1938-11-01 Phoenix Metal Cap Co Inc Closure for containers
FR2598137B1 (fr) 1986-05-05 1989-05-26 Astraplastique Sa Dispositif de bouchon a visser inviolable et son procede d'assemblage.
DE3835720A1 (de) 1988-10-20 1990-05-03 Wimmer Pharma Gummi Gmbh Verschluss fuer eine medikamentenflasche und verfahren zur herstellung dieses verschlusses
DE4340910C1 (de) * 1993-12-01 1995-01-26 Freudenberg Carl Fa Verschluß für eine Flasche
DE19539897A1 (de) * 1995-09-13 1997-03-20 Pohl Gmbh Kappenverschluß für einen Behälter
US6209738B1 (en) * 1998-04-20 2001-04-03 Becton, Dickinson And Company Transfer set for vials and medical containers
DE10127823C1 (de) 2001-06-07 2002-08-22 West Pharm Serv Drug Res Ltd Verschluss für eine Medikamentenflasche sowie Verfahren zu dessen Herstellung
DE10138191B4 (de) 2001-08-03 2004-02-26 Helvoet Pharma Belgium N.V. Verschluss für Infusions- oder Transfusionsflaschen
GB2392795B (en) 2002-09-04 2006-04-19 B & W Loudspeakers Suspension for the voice coil of a loudspeaker drive unit
DE10311154A1 (de) * 2003-03-14 2004-09-23 Helvoet Pharma Belgium N.V. Für pharmazeutische Verwendung dienende Überkappe mit Verschlussstopfen

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102014226900A1 (de) * 2014-12-23 2016-06-23 B. Braun Melsungen Ag Verschlusskappensystem für ein medizinisches Fluidspeicherbehältnis
DE102014226900B4 (de) * 2014-12-23 2017-10-26 B. Braun Melsungen Ag Verschlusskappensystem für ein medizinisches Fluidspeicherbehältnis

Also Published As

Publication number Publication date
ES2355638T3 (es) 2011-03-29
PL1955964T3 (pl) 2011-04-29
ATE488446T1 (de) 2010-12-15
EP1955964A1 (de) 2008-08-13
GB0701326D0 (en) 2007-03-07
DE602008003461D1 (de) 2010-12-30

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