EP1917532A4 - Anticorps monoclonal anti-d-dimère utilisé comme agent de diagnostic pour détecter un d-dimère, une fibrine réticulée et ses dérivés renfermant les d-dimères - Google Patents

Anticorps monoclonal anti-d-dimère utilisé comme agent de diagnostic pour détecter un d-dimère, une fibrine réticulée et ses dérivés renfermant les d-dimères

Info

Publication number
EP1917532A4
EP1917532A4 EP05774217A EP05774217A EP1917532A4 EP 1917532 A4 EP1917532 A4 EP 1917532A4 EP 05774217 A EP05774217 A EP 05774217A EP 05774217 A EP05774217 A EP 05774217A EP 1917532 A4 EP1917532 A4 EP 1917532A4
Authority
EP
European Patent Office
Prior art keywords
dimer
detecting
derivatives containing
monoclonal antibody
crosslinked fibrin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05774217A
Other languages
German (de)
English (en)
Other versions
EP1917532A1 (fr
Inventor
Hyun-Ju Doh
Doo-Sik Kim
Kwang-Hoe Chung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biobud Co Ltd
Princeton Biomeditech Corp
Original Assignee
Biobud Co Ltd
Princeton Biomeditech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biobud Co Ltd, Princeton Biomeditech Corp filed Critical Biobud Co Ltd
Publication of EP1917532A1 publication Critical patent/EP1917532A1/fr
Publication of EP1917532A4 publication Critical patent/EP1917532A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP05774217A 2005-07-29 2005-07-29 Anticorps monoclonal anti-d-dimère utilisé comme agent de diagnostic pour détecter un d-dimère, une fibrine réticulée et ses dérivés renfermant les d-dimères Withdrawn EP1917532A4 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/KR2005/002491 WO2007013709A1 (fr) 2005-07-29 2005-07-29 Anticorps monoclonal anti-d-dimere utilise comme agent de diagnostic pour detecter un d-dimere, une fibrine reticulee et ses derives renfermant les d-dimeres

Publications (2)

Publication Number Publication Date
EP1917532A1 EP1917532A1 (fr) 2008-05-07
EP1917532A4 true EP1917532A4 (fr) 2009-10-21

Family

ID=37683573

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05774217A Withdrawn EP1917532A4 (fr) 2005-07-29 2005-07-29 Anticorps monoclonal anti-d-dimère utilisé comme agent de diagnostic pour détecter un d-dimère, une fibrine réticulée et ses dérivés renfermant les d-dimères

Country Status (2)

Country Link
EP (1) EP1917532A4 (fr)
WO (1) WO2007013709A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9206250B2 (en) 2010-04-01 2015-12-08 Lsi Medience Corporation Monoclonal antibodies and method of immunological analysis of D-dimer
CN102010472B (zh) * 2010-10-22 2012-09-05 上海贝西生物科技有限公司 一种抗d-二聚体单克隆抗体及其用途
CN102183652A (zh) * 2011-03-03 2011-09-14 协和生物制药（天津）有限公司 D-二聚体时间分辨荧光免疫分析试剂盒及其制备方法
RU2742279C2 (ru) * 2016-02-22 2021-02-04 ЭлЭсАй МЕДИЕНС КОРПОРЕЙШН Реагент для оценки продукта расщепления перекрестносшитого фибрина и способ такой оценки
AR121388A1 (es) * 2020-02-20 2022-06-01 Hoffmann La Roche Anticuerpos anti dímero d recombinantes, procedimientos y utilizaciones de los mismos
CN115948342B (zh) * 2022-12-19 2023-10-03 山东大学 一种cho细胞株、d-二聚体单克隆抗体及其应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003000736A1 (fr) * 2001-06-26 2003-01-03 Agen Biomedical Limited Anticorps humanises derives de dd-3b6/22, specifiques du fragment d-dimere de la fibrine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206140A (en) * 1988-06-24 1993-04-27 Research Corporation Technologies, Inc. Assay for soluble crosslinked fibrin polymers

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003000736A1 (fr) * 2001-06-26 2003-01-03 Agen Biomedical Limited Anticorps humanises derives de dd-3b6/22, specifiques du fragment d-dimere de la fibrine

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DEMPFLE CARL-ERIK ET AL: "The Fibrin Assay Comparison Trial (FACT): Evaluation of 23 quantitative D-dimer assays as basis for the development of D-dimer calibrators", THROMBOSIS AND HAEMOSTASIS, vol. 85, no. 4, April 2001 (2001-04-01), pages 671 - 678, XP009121557, ISSN: 0340-6245 *
KOGAN A ET AL: "Proteolytic degradation of D-dimer for epitope determination of anti-D-dimer antibodies", FIBRINOLYSIS AND PROTEOLYSIS, vol. 14, no. Supplement 1, June 2000 (2000-06-01), & XVTH INTERNATIONAL CONGRESS ON FIBRINOLYSIS AND PROTEOLYSIS; HAMAMATSU, JAPAN; JUNE 25-29, 2000, pages 76, XP009121561, ISSN: 1369-0191 *
LUGOVSKOY E V ET AL: "Two monoclonal antibodies to D-dimer-specific inhibitors of fibrin polymerization", THROMBOSIS RESEARCH, vol. 113, no. 3-4, 2004, pages 251 - 259, XP002541874, ISSN: 0049-3848 *
PFLTZNER S A ET AL: "FIBRIN DETECTED IN PLASMA OF PATIENTS WITH DISSEMINATED INTRAVASCULAR COAGULATION BY FIBRIN-SPECIFIC ANTIBODIES CONSISTS PRIMARILY OF HIGH MOLECULAR WEIGHT FACTOR XIIIA-CROSSLINKED AND PLASMIN-MODIFIED COMPLEXES PARTIALLY CONTAINING FIBRINOPEPTIDE A", THROMBOSIS AND HAEMOSTASIS, SCHATTAUER GMBH, DE; US, vol. 78, no. 3, 1 September 1997 (1997-09-01), pages 1069 - 1078, XP002912988, ISSN: 0340-6245 *
See also references of WO2007013709A1 *
WYLIE F G ET AL: "Partial identification of the epitope on D-dimer for monoclonal antibody, DD-3B6/22", BLOOD COAGULATION AND FIBRINOLYSIS, vol. 8, no. 2, 1997, pages 87 - 96, XP009121560, ISSN: 0957-5235 *

Also Published As

Publication number Publication date
EP1917532A1 (fr) 2008-05-07
WO2007013709A1 (fr) 2007-02-01

Similar Documents

Publication Publication Date Title
AP2787A (en) Methods, immunoassays and devices for detection ofanti-lipoidal antibodies
IL272883A (en) Monoclonal antibodies and their uses
EP1866637A4 (fr) Element de test de fluide organique a des fins de detection d'analyte
ZA200708240B (en) Dual path immunoassay device
BRPI0722081A2 (pt) Complexo metálico, composto polimérico e dispositivo contendo os mesmos
NL1032452A1 (nl) Menselijke monoklonale antilichamen tegen activine receptor-achtig kinase-1.
PL1877415T3 (pl) Nowe strategie znakowania dla czułego wykrywania analitów
EP1745289A4 (fr) Procedes et anticorps pour la detection de nitrofuranes
EP1940466A4 (fr) Anticorps monoclonal anti-addl et leur utilisation
EP1879049A4 (fr) Dispositif de detection d'informations concernant l 'espace, et systeme de detection d 'informations concernant l 'espace utilisant le dispositif
HK1116864A1 (en) 5-fluoro-uracil immunoassay 5--
EP1877795A4 (fr) Profilage diagnostique d'anticorps seriques
DE502006004001D1 (de) Wägevorrichtung, insbesondere mehrspur-wägevorrichtung
AP2316A (en) Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same.
EP1917532A4 (fr) Anticorps monoclonal anti-d-dimère utilisé comme agent de diagnostic pour détecter un d-dimère, une fibrine réticulée et ses dérivés renfermant les d-dimères
HK1115598A1 (en) Humanised antibodies specific for nogo-a and pharmaceutical uses thereof
EP2087360A4 (fr) Dispositif d'analyse revelant la presence de sang occulte
FR2894983B1 (fr) Test de caracterisation des anticorps.
WO2006091962A3 (fr) Detection de composes affectant l'activite therapeutique
WO2007002096A3 (fr) Methodes et compositions permettant de cibler ifnar2
ZA200800047B (en) Humanised antibodies specific for NOGO-A and pharmaceutical uses thereof
EP2010652A4 (fr) Protéine, anticorps et mesure de la protéine
NL1030198A1 (nl) Spanningloosheiddetector (bovenleidingtester).
Blank et al. Method for determining an analyte
ES1060836Y (es) Dispositivo de medicion.

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20080130

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

A4 Supplementary search report drawn up and despatched

Effective date: 20090916

17Q First examination report despatched

Effective date: 20100211

DAX Request for extension of the european patent (deleted)
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20140201