EP1917532A4 - Monoclonal antibody against d-dimer and diagnosis agent for detecting d-dimer, crosslinked fibrin and its derivatives containing d-dimer by using the antibody - Google Patents

Monoclonal antibody against d-dimer and diagnosis agent for detecting d-dimer, crosslinked fibrin and its derivatives containing d-dimer by using the antibody

Info

Publication number
EP1917532A4
EP1917532A4 EP05774217A EP05774217A EP1917532A4 EP 1917532 A4 EP1917532 A4 EP 1917532A4 EP 05774217 A EP05774217 A EP 05774217A EP 05774217 A EP05774217 A EP 05774217A EP 1917532 A4 EP1917532 A4 EP 1917532A4
Authority
EP
European Patent Office
Prior art keywords
dimer
detecting
derivatives containing
monoclonal antibody
crosslinked fibrin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05774217A
Other languages
German (de)
French (fr)
Other versions
EP1917532A1 (en
Inventor
Hyun-Ju Doh
Doo-Sik Kim
Kwang-Hoe Chung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biobud Co Ltd
Princeton Biomeditech Corp
Original Assignee
Biobud Co Ltd
Princeton Biomeditech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biobud Co Ltd, Princeton Biomeditech Corp filed Critical Biobud Co Ltd
Publication of EP1917532A1 publication Critical patent/EP1917532A1/en
Publication of EP1917532A4 publication Critical patent/EP1917532A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
EP05774217A 2005-07-29 2005-07-29 Monoclonal antibody against d-dimer and diagnosis agent for detecting d-dimer, crosslinked fibrin and its derivatives containing d-dimer by using the antibody Withdrawn EP1917532A4 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/KR2005/002491 WO2007013709A1 (en) 2005-07-29 2005-07-29 Monoclonal antibody against d-dimer and diagnosis agent for detecting d-dimer, crosslinked fibrin and its derivatives containing d-dimer by using the antibody

Publications (2)

Publication Number Publication Date
EP1917532A1 EP1917532A1 (en) 2008-05-07
EP1917532A4 true EP1917532A4 (en) 2009-10-21

Family

ID=37683573

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05774217A Withdrawn EP1917532A4 (en) 2005-07-29 2005-07-29 Monoclonal antibody against d-dimer and diagnosis agent for detecting d-dimer, crosslinked fibrin and its derivatives containing d-dimer by using the antibody

Country Status (2)

Country Link
EP (1) EP1917532A4 (en)
WO (1) WO2007013709A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5860394B2 (en) * 2010-04-01 2016-02-16 株式会社Ｌｓｉメディエンス Immunoassay for novel monoclonal antibody and D-dimer
CN102010472B (en) * 2010-10-22 2012-09-05 上海贝西生物科技有限公司 Anti-D-dimer monoclonal antibody and application thereof
CN102183652A (en) * 2011-03-03 2011-09-14 协和生物制药（天津）有限公司 Kit for time resolved fluoroimmunoassay of D-dimer and preparation method thereof
KR102589054B1 (en) * 2016-02-22 2023-10-12 가부시키가이샤 엘에스아이 메디엔스 Reagents and methods for measuring cross-linked fibrin degradation products
CN115135670A (en) * 2020-02-20 2022-09-30 豪夫迈·罗氏有限公司 anti-D-dimer recombinant antibodies, methods and uses thereof
CN115948342B (en) * 2022-12-19 2023-10-03 山东大学 CHO cell strain, D-dimer monoclonal antibody and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003000736A1 (en) * 2001-06-26 2003-01-03 Agen Biomedical Limited Humanized antibodies derived from dd-3b6/22, specific for the d-dimer fragment of fibrin

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206140A (en) * 1988-06-24 1993-04-27 Research Corporation Technologies, Inc. Assay for soluble crosslinked fibrin polymers

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003000736A1 (en) * 2001-06-26 2003-01-03 Agen Biomedical Limited Humanized antibodies derived from dd-3b6/22, specific for the d-dimer fragment of fibrin

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DEMPFLE CARL-ERIK ET AL: "The Fibrin Assay Comparison Trial (FACT): Evaluation of 23 quantitative D-dimer assays as basis for the development of D-dimer calibrators", THROMBOSIS AND HAEMOSTASIS, vol. 85, no. 4, April 2001 (2001-04-01), pages 671 - 678, XP009121557, ISSN: 0340-6245 *
KOGAN A ET AL: "Proteolytic degradation of D-dimer for epitope determination of anti-D-dimer antibodies", FIBRINOLYSIS AND PROTEOLYSIS, vol. 14, no. Supplement 1, June 2000 (2000-06-01), & XVTH INTERNATIONAL CONGRESS ON FIBRINOLYSIS AND PROTEOLYSIS; HAMAMATSU, JAPAN; JUNE 25-29, 2000, pages 76, XP009121561, ISSN: 1369-0191 *
LUGOVSKOY E V ET AL: "Two monoclonal antibodies to D-dimer-specific inhibitors of fibrin polymerization", THROMBOSIS RESEARCH, vol. 113, no. 3-4, 2004, pages 251 - 259, XP002541874, ISSN: 0049-3848 *
PFLTZNER S A ET AL: "FIBRIN DETECTED IN PLASMA OF PATIENTS WITH DISSEMINATED INTRAVASCULAR COAGULATION BY FIBRIN-SPECIFIC ANTIBODIES CONSISTS PRIMARILY OF HIGH MOLECULAR WEIGHT FACTOR XIIIA-CROSSLINKED AND PLASMIN-MODIFIED COMPLEXES PARTIALLY CONTAINING FIBRINOPEPTIDE A", THROMBOSIS AND HAEMOSTASIS, SCHATTAUER GMBH, DE; US, vol. 78, no. 3, 1 September 1997 (1997-09-01), pages 1069 - 1078, XP002912988, ISSN: 0340-6245 *
See also references of WO2007013709A1 *
WYLIE F G ET AL: "Partial identification of the epitope on D-dimer for monoclonal antibody, DD-3B6/22", BLOOD COAGULATION AND FIBRINOLYSIS, vol. 8, no. 2, 1997, pages 87 - 96, XP009121560, ISSN: 0957-5235 *

Also Published As

Publication number Publication date
WO2007013709A1 (en) 2007-02-01
EP1917532A1 (en) 2008-05-07

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