EP1917532A4 - Monoklonaler antikörper gegen d-dimer und diagnosemittel zum nachweis von d-dimer, d-dimer enthaltendem quervernetztem fibrin und dessen derivaten unter verwendung des antikörpers - Google Patents

Monoklonaler antikörper gegen d-dimer und diagnosemittel zum nachweis von d-dimer, d-dimer enthaltendem quervernetztem fibrin und dessen derivaten unter verwendung des antikörpers

Info

Publication number
EP1917532A4
EP1917532A4 EP05774217A EP05774217A EP1917532A4 EP 1917532 A4 EP1917532 A4 EP 1917532A4 EP 05774217 A EP05774217 A EP 05774217A EP 05774217 A EP05774217 A EP 05774217A EP 1917532 A4 EP1917532 A4 EP 1917532A4
Authority
EP
European Patent Office
Prior art keywords
dimer
detecting
derivatives containing
monoclonal antibody
crosslinked fibrin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05774217A
Other languages
English (en)
French (fr)
Other versions
EP1917532A1 (de
Inventor
Hyun-Ju Doh
Doo-Sik Kim
Kwang-Hoe Chung
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biobud Co Ltd
Princeton Biomeditech Corp
Original Assignee
Biobud Co Ltd
Princeton Biomeditech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biobud Co Ltd, Princeton Biomeditech Corp filed Critical Biobud Co Ltd
Publication of EP1917532A1 publication Critical patent/EP1917532A1/de
Publication of EP1917532A4 publication Critical patent/EP1917532A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
EP05774217A 2005-07-29 2005-07-29 Monoklonaler antikörper gegen d-dimer und diagnosemittel zum nachweis von d-dimer, d-dimer enthaltendem quervernetztem fibrin und dessen derivaten unter verwendung des antikörpers Withdrawn EP1917532A4 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/KR2005/002491 WO2007013709A1 (en) 2005-07-29 2005-07-29 Monoclonal antibody against d-dimer and diagnosis agent for detecting d-dimer, crosslinked fibrin and its derivatives containing d-dimer by using the antibody

Publications (2)

Publication Number Publication Date
EP1917532A1 EP1917532A1 (de) 2008-05-07
EP1917532A4 true EP1917532A4 (de) 2009-10-21

Family

ID=37683573

Family Applications (1)

Application Number Title Priority Date Filing Date
EP05774217A Withdrawn EP1917532A4 (de) 2005-07-29 2005-07-29 Monoklonaler antikörper gegen d-dimer und diagnosemittel zum nachweis von d-dimer, d-dimer enthaltendem quervernetztem fibrin und dessen derivaten unter verwendung des antikörpers

Country Status (2)

Country Link
EP (1) EP1917532A4 (de)
WO (1) WO2007013709A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107602698A (zh) * 2010-04-01 2018-01-19 美迪恩斯生命科技株式会社 新的单克隆抗体以及d二聚体的免疫学测定方法
CN102010472B (zh) * 2010-10-22 2012-09-05 上海贝西生物科技有限公司 一种抗d-二聚体单克隆抗体及其用途
CN102183652A (zh) * 2011-03-03 2011-09-14 协和生物制药（天津）有限公司 D-二聚体时间分辨荧光免疫分析试剂盒及其制备方法
RU2742279C2 (ru) * 2016-02-22 2021-02-04 ЭлЭсАй МЕДИЕНС КОРПОРЕЙШН Реагент для оценки продукта расщепления перекрестносшитого фибрина и способ такой оценки
BR112022013217A2 (pt) * 2020-02-20 2022-09-13 Hoffmann La Roche Anticorpos recombinantes anti d-dímero, métodos e usos dos mesmos
CN115948342B (zh) * 2022-12-19 2023-10-03 山东大学 一种cho细胞株、d-二聚体单克隆抗体及其应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003000736A1 (en) * 2001-06-26 2003-01-03 Agen Biomedical Limited Humanized antibodies derived from dd-3b6/22, specific for the d-dimer fragment of fibrin

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206140A (en) * 1988-06-24 1993-04-27 Research Corporation Technologies, Inc. Assay for soluble crosslinked fibrin polymers

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003000736A1 (en) * 2001-06-26 2003-01-03 Agen Biomedical Limited Humanized antibodies derived from dd-3b6/22, specific for the d-dimer fragment of fibrin

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DEMPFLE CARL-ERIK ET AL: "The Fibrin Assay Comparison Trial (FACT): Evaluation of 23 quantitative D-dimer assays as basis for the development of D-dimer calibrators", THROMBOSIS AND HAEMOSTASIS, vol. 85, no. 4, April 2001 (2001-04-01), pages 671 - 678, XP009121557, ISSN: 0340-6245 *
KOGAN A ET AL: "Proteolytic degradation of D-dimer for epitope determination of anti-D-dimer antibodies", FIBRINOLYSIS AND PROTEOLYSIS, vol. 14, no. Supplement 1, June 2000 (2000-06-01), & XVTH INTERNATIONAL CONGRESS ON FIBRINOLYSIS AND PROTEOLYSIS; HAMAMATSU, JAPAN; JUNE 25-29, 2000, pages 76, XP009121561, ISSN: 1369-0191 *
LUGOVSKOY E V ET AL: "Two monoclonal antibodies to D-dimer-specific inhibitors of fibrin polymerization", THROMBOSIS RESEARCH, vol. 113, no. 3-4, 2004, pages 251 - 259, XP002541874, ISSN: 0049-3848 *
PFLTZNER S A ET AL: "FIBRIN DETECTED IN PLASMA OF PATIENTS WITH DISSEMINATED INTRAVASCULAR COAGULATION BY FIBRIN-SPECIFIC ANTIBODIES CONSISTS PRIMARILY OF HIGH MOLECULAR WEIGHT FACTOR XIIIA-CROSSLINKED AND PLASMIN-MODIFIED COMPLEXES PARTIALLY CONTAINING FIBRINOPEPTIDE A", THROMBOSIS AND HAEMOSTASIS, SCHATTAUER GMBH, DE; US, vol. 78, no. 3, 1 September 1997 (1997-09-01), pages 1069 - 1078, XP002912988, ISSN: 0340-6245 *
See also references of WO2007013709A1 *
WYLIE F G ET AL: "Partial identification of the epitope on D-dimer for monoclonal antibody, DD-3B6/22", BLOOD COAGULATION AND FIBRINOLYSIS, vol. 8, no. 2, 1997, pages 87 - 96, XP009121560, ISSN: 0957-5235 *

Also Published As

Publication number Publication date
WO2007013709A1 (en) 2007-02-01
EP1917532A1 (de) 2008-05-07

Similar Documents

Publication Publication Date Title
AP2787A (en) Methods, immunoassays and devices for detection ofanti-lipoidal antibodies
IL272883A (en) Monoclonal antibodies and their uses
EP1866637A4 (de) Komponente für die untersuchung von körperflüssigkeiten zum analytnachweis
ZA200708240B (en) Dual path immunoassay device
BRPI0722081A2 (pt) Complexo metálico, composto polimérico e dispositivo contendo os mesmos
NL1032452A1 (nl) Menselijke monoklonale antilichamen tegen activine receptor-achtig kinase-1.
PL1877415T3 (pl) Nowe strategie znakowania dla czułego wykrywania analitów
EP1745289A4 (de) Verfahren und antikörper zum nitrofurannachweis
EP1940466A4 (de) Monoklonaler antikörper gegen addl und anwendung davon
EP1879049A4 (de) Rauminformations-detektionseinrichtung und rauminformations-detektionssystem mit der einrichtung
HK1116864A1 (en) 5-fluoro-uracil immunoassay 5--
EP1877795A4 (de) Diagnostische profilerstellung von serumantikörpern
DE502006004001D1 (de) Wägevorrichtung, insbesondere mehrspur-wägevorrichtung
EP1917532A4 (de) Monoklonaler antikörper gegen d-dimer und diagnosemittel zum nachweis von d-dimer, d-dimer enthaltendem quervernetztem fibrin und dessen derivaten unter verwendung des antikörpers
AP2007003884A0 (en) Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same.
HK1115598A1 (en) Humanised antibodies specific for nogo-a and pharmaceutical uses thereof
EP2087360A4 (de) Testvorrichtung für okkultes blut
FI20055133A (fi) Iskulaite
FR2894983B1 (fr) Test de caracterisation des anticorps.
WO2007002096A3 (en) Methods and compositions for targeting ifnar2
ZA200800047B (en) Humanised antibodies specific for NOGO-A and pharmaceutical uses thereof
EP2010652A4 (de) Protein, antikörper und messung des proteins
NL1030198A1 (nl) Spanningloosheiddetector (bovenleidingtester).
Blank et al. Method for determining an analyte
ES1060836Y (es) Dispositivo de medicion.

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20080130

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR

A4 Supplementary search report drawn up and despatched

Effective date: 20090916

17Q First examination report despatched

Effective date: 20100211

DAX Request for extension of the european patent (deleted)
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20140201