EP1897525A3 - Method for producing and a system for cooling a hot-filled softgel capsule - Google Patents

Method for producing and a system for cooling a hot-filled softgel capsule Download PDF

Info

Publication number
EP1897525A3
EP1897525A3 EP07113891A EP07113891A EP1897525A3 EP 1897525 A3 EP1897525 A3 EP 1897525A3 EP 07113891 A EP07113891 A EP 07113891A EP 07113891 A EP07113891 A EP 07113891A EP 1897525 A3 EP1897525 A3 EP 1897525A3
Authority
EP
European Patent Office
Prior art keywords
chilled liquid
capsule
flowing
hot
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
EP07113891A
Other languages
German (de)
French (fr)
Other versions
EP1897525B1 (en
EP1897525A2 (en
Inventor
John Zazula
Rueben 0. Zielinski
Richard Glawson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RP Scherer Technologies LLC
Original Assignee
RP Scherer Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RP Scherer Technologies LLC filed Critical RP Scherer Technologies LLC
Publication of EP1897525A2 publication Critical patent/EP1897525A2/en
Publication of EP1897525A3 publication Critical patent/EP1897525A3/en
Application granted granted Critical
Publication of EP1897525B1 publication Critical patent/EP1897525B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2200/00—General characteristics or adaptations
    • A61J2200/40—Heating or cooling means; Combinations thereof
    • A61J2200/44—Cooling means

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Formation And Processing Of Food Products (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Devices That Are Associated With Refrigeration Equipment (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)

Abstract

A system for producing a hot-filled softgel capsule (20) utilizes a chilled liquid (200). The chilled liquid is routed through a chilled liquid conveyor tray into a chilled liquid bath. The chilled liquid conveyor tray (320) directs the flowing chilled liquid into a flowing chilled liquid layer. Softgel capsules having a heated fill material are deposited in the flowing chilled liquid layer. The chilled liquid layer cools the capsule by transferring heat from the capsule to the chilled liquid. The flowing chilled liquid layer transports the capsule out of the chilled liquid conveyor tray (320) into a chilled liquid bath. A capsule transfer conveyor transports the capsule out of the chilled liquid bath to a chilled liquid removal device (800). The chilled liquid removal device removes the chilled liquid from the capsule.
EP07113891.1A 2006-08-08 2007-08-06 Method for producing a hot-filled softgel capsule and system for cooling a hot-filled softgel capsule Active EP1897525B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11/500,719 US20080038334A1 (en) 2006-08-08 2006-08-08 Method for producing and a system for cooling a hot-filled softgel capsule

Publications (3)

Publication Number Publication Date
EP1897525A2 EP1897525A2 (en) 2008-03-12
EP1897525A3 true EP1897525A3 (en) 2009-05-13
EP1897525B1 EP1897525B1 (en) 2016-02-24

Family

ID=38980627

Family Applications (1)

Application Number Title Priority Date Filing Date
EP07113891.1A Active EP1897525B1 (en) 2006-08-08 2007-08-06 Method for producing a hot-filled softgel capsule and system for cooling a hot-filled softgel capsule

Country Status (9)

Country Link
US (2) US20080038334A1 (en)
EP (1) EP1897525B1 (en)
JP (1) JP4890379B2 (en)
CN (1) CN101239022B (en)
AR (1) AR062290A1 (en)
AU (1) AU2007203660B2 (en)
BR (1) BRPI0705865B8 (en)
CA (1) CA2596104C (en)
MX (1) MX2007009462A (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8755437B2 (en) 2011-03-17 2014-06-17 Mediatek Inc. Method and apparatus for derivation of spatial motion vector candidate and motion vector prediction candidate
EP2710993A4 (en) * 2011-05-18 2015-01-07 Chang Sung Softgel System Ltd Equipment for manufacturing a vegetable gelatin capsule
US10240867B2 (en) * 2012-02-01 2019-03-26 Revive Electronics, LLC Methods and apparatuses for drying electronic devices
CN105411855A (en) * 2015-12-24 2016-03-23 山东省化工研究院 Medical dropping pill device and method for preparing brain strengthening and hair blacking dropping pills with same
CN113057948B (en) * 2020-01-02 2023-01-17 上海信谊万象药业股份有限公司 Preparation process of soft capsule preparation
US11111087B1 (en) * 2020-08-26 2021-09-07 Xiongqing Yu Transfer system for soft gels
CN112494327B (en) * 2020-10-20 2022-05-27 浙江伯是购厨具有限公司 Traditional chinese medicine frying pan with remind function

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB602874A (en) * 1944-02-17 1948-06-04 Robert William Gunnell Improvements in and relating to the manufacture of capsules
US2545299A (en) * 1947-06-23 1951-03-13 Norton Co Apparatus and method for handling capsules
US2958171A (en) * 1956-07-20 1960-11-01 Deckers Joseph Apparatus for the simultaneous manufacture and filling of packages
GB1145734A (en) * 1965-06-10 1969-03-19 Higham Stanley Russell Means for administering medicaments
WO1990008527A1 (en) * 1989-01-26 1990-08-09 R.P. Scherer Corporation Textured softgels and method and apparatus for the manufacture thereof
US6174466B1 (en) * 1998-05-08 2001-01-16 Warner-Lambert Company Methods for making seamless capsules

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1145734A (en) * 1911-09-09 1915-07-06 Otto Abeling Road-rammer.
US4422985A (en) * 1982-09-24 1983-12-27 Morishita Jintan Co., Ltd. Method and apparatus for encapsulation of a liquid or meltable solid material
US4539060A (en) * 1983-02-18 1985-09-03 Warner-Lambert Company Apparatus and method of sealing capsules
US4609403A (en) * 1984-03-12 1986-09-02 Warner-Lambert Company Foam soft gelatin capsules and their method of manufacture
US5146758A (en) * 1991-03-04 1992-09-15 Herman Norman L Process of producing soft elastic gelatin capsules
DE4201178C2 (en) * 1992-01-17 1995-12-07 Alfatec Pharma Gmbh Process for the production of soft gelatin capsules by a dropping process
US5672300A (en) * 1992-08-10 1997-09-30 R. P. Scherer Corporation Method for striping or marbleizing capsules
GB9226238D0 (en) * 1992-12-16 1993-02-10 Scherer Ltd R P Encapsulation apparatus and process
JPH0810313A (en) * 1994-07-01 1996-01-16 Freunt Ind Co Ltd Manufacture of seamless capsule
DE4446468A1 (en) * 1994-12-23 1996-06-27 Basf Ag Process for the production of coated tablets
US5595757A (en) * 1995-03-29 1997-01-21 Warner-Lambert Company Seamless capsules
US5888538A (en) * 1995-03-29 1999-03-30 Warner-Lambert Company Methods and apparatus for making seamless capsules
EP1140012B1 (en) * 1998-12-17 2004-03-03 Alza Corporation Conversion of liquid filled gelatin capsules into controlled release systems by multiple coatings
EP2042165A1 (en) * 2007-09-28 2009-04-01 Swiss Caps Rechte und Lizenzen AG Hot-melt filled soft capsules

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB602874A (en) * 1944-02-17 1948-06-04 Robert William Gunnell Improvements in and relating to the manufacture of capsules
US2545299A (en) * 1947-06-23 1951-03-13 Norton Co Apparatus and method for handling capsules
US2958171A (en) * 1956-07-20 1960-11-01 Deckers Joseph Apparatus for the simultaneous manufacture and filling of packages
GB1145734A (en) * 1965-06-10 1969-03-19 Higham Stanley Russell Means for administering medicaments
WO1990008527A1 (en) * 1989-01-26 1990-08-09 R.P. Scherer Corporation Textured softgels and method and apparatus for the manufacture thereof
US6174466B1 (en) * 1998-05-08 2001-01-16 Warner-Lambert Company Methods for making seamless capsules

Also Published As

Publication number Publication date
AU2007203660B2 (en) 2013-05-30
JP2008049154A (en) 2008-03-06
BRPI0705865B8 (en) 2021-05-25
EP1897525B1 (en) 2016-02-24
BRPI0705865B1 (en) 2019-12-10
JP4890379B2 (en) 2012-03-07
MX2007009462A (en) 2009-02-04
CN101239022A (en) 2008-08-13
EP1897525A2 (en) 2008-03-12
US20100219543A1 (en) 2010-09-02
CA2596104A1 (en) 2008-02-08
CA2596104C (en) 2016-06-14
AU2007203660A1 (en) 2008-02-28
AR062290A1 (en) 2008-10-29
BRPI0705865A2 (en) 2008-11-25
US20080038334A1 (en) 2008-02-14
CN101239022B (en) 2013-07-17

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