GB602874A - Improvements in and relating to the manufacture of capsules - Google Patents
Improvements in and relating to the manufacture of capsulesInfo
- Publication number
- GB602874A GB602874A GB3826/45A GB382645A GB602874A GB 602874 A GB602874 A GB 602874A GB 3826/45 A GB3826/45 A GB 3826/45A GB 382645 A GB382645 A GB 382645A GB 602874 A GB602874 A GB 602874A
- Authority
- GB
- United Kingdom
- Prior art keywords
- liquid
- cooling
- chamber
- coating liquid
- maintained
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Detergent Compositions (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Abstract
6 0 2,8 7 4. Capsule-forming apparatus. GUNNELL, R. W. Feb. 15, 1945, No. 3826. Convention date, Feb. 17, 1944. [Class 81(i)] In a method for the formation of capsules, superposed layers of capsule-coating liquid and a cooling liquid of different gravities and mutually immiscible, are maintained within a chamber, a fluid capsule substance is introduced into the coating liquid and caused to pass therefrom into the cooling liquid. The coating liquid, e.g. gelatin-glycerine solution, may contain a substance, e.g. soap, sulphonated higher alcohols, &c., reducing the surface tension at its interface witn the cooling liquid, e.g. kerosene, naphtha, petroleum etner, &c., mixed with carbon tetrachloride, perchlorethylene, &c. If desired, the latter liquids may constitute an intermediate layer, with an upper layer of water, or water admixed with alcohol, acetone, &c. In Fig. 1, the content substance passes to nozzles 11 in the chamber via cooling- jacketed pipes 12, being advantageously cooled, say, to 10-20‹F. Each nozzle is formed with a slidable pin 18 adapted to close its orifice when not in use. Regulating valve controls 26 are shown, the drops on formation being visible through windows 29. The coating liquid is supplied from receptacle 66 provided with a heater 65 and thermostat 68, stand pipe 62 ensuring the necessary hydrostatic head of liquid. The temperature of the gelatin is maintained within the chamber by heating strips 32 lying parallel to the rows of nozzles 11. The cooling liquid 35 is maintained at 40-60‹F. by cooling cells 36 in the form of hollow plates through which a refrigerant passes via pipes 38, 37, 41. The capsules reaching the surface 42 of the liquid are removed by a rotating paddle 43 over a weir 45 to a perforated draining plate 46 and collecting receptacle 47. The liquid draining into vessel 48 is pumped through a cooling coil 52 back to the chamber through lines 56 having upwardly directed openings 57.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US602874XA | 1944-02-17 | 1944-02-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB602874A true GB602874A (en) | 1948-06-04 |
Family
ID=22028562
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB3826/45A Expired GB602874A (en) | 1944-02-17 | 1945-02-15 | Improvements in and relating to the manufacture of capsules |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB602874A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1897525A3 (en) * | 2006-08-08 | 2009-05-13 | R.P. Scherer Technologies, Inc. | Method for producing and a system for cooling a hot-filled softgel capsule |
-
1945
- 1945-02-15 GB GB3826/45A patent/GB602874A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1897525A3 (en) * | 2006-08-08 | 2009-05-13 | R.P. Scherer Technologies, Inc. | Method for producing and a system for cooling a hot-filled softgel capsule |
| CN101239022B (en) * | 2006-08-08 | 2013-07-17 | R·P·舍勒科技有限责任公司 | Hot filling soft capsule manufacture method and cooling system |
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