CN105411855A - Medical dropping pill device and method for preparing brain strengthening and hair blacking dropping pills with same - Google Patents

Medical dropping pill device and method for preparing brain strengthening and hair blacking dropping pills with same Download PDF

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Publication number
CN105411855A
CN105411855A CN201510983386.7A CN201510983386A CN105411855A CN 105411855 A CN105411855 A CN 105411855A CN 201510983386 A CN201510983386 A CN 201510983386A CN 105411855 A CN105411855 A CN 105411855A
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Prior art keywords
hot water
medicine liquid
liquid tank
outlet
tank
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CN201510983386.7A
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Chinese (zh)
Inventor
史法胜
郑璟
王立芹
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CHEMICAL INST SHANDONG PROV
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CHEMICAL INST SHANDONG PROV
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Priority to CN201510983386.7A priority Critical patent/CN105411855A/en
Publication of CN105411855A publication Critical patent/CN105411855A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/06Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/638Ligustrum, e.g. Chinese privet
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a medical dropping pill device and a method for preparing brain strengthening and hair blacking dropping pills with the same. The device comprises a liquid medicine tank which is provided with a hot water inlet, a hot water outlet, a liquid medicine inlet and a liquid medicine outlet, wherein the liquid medicine outlet is connected with a dropper head through a pill outlet pipeline provided with a control valve, a cooling container containing a coolant is arranged below the dropper head, the pill outlet pipeline is sleeved with a condenser pipe, and the condenser pipe is provided with a hot water inlet connected with the hot water outlet and a circulating water outlet connected with the hot water inlet. The method for preparing the brain strengthening and hair blacking dropping pills comprises the steps of concentrating radix rehmanniae extracts, polygonum multiflorum extracts, glossy privet fruit extracts and eclipta extracts, mixing the extract mixture with polyethylene glycol 4000, adding the product into the liquid medicine tank, and dropping the product into the cooling container through the pill outlet pipeline connected with the dropper head.

Description

Medicinal drop pill device and utilize it to make the method for brain-benefiting and hair-blackening drop pill
Technical field
The present invention relates to a kind of medicinal drop pill device and utilize it to make the method for brain-benefiting and hair-blackening drop pill.
Background technology
Dropping preparation method pill is by medicine dissolution, emulsifying or is suspended in the substrate of suitable melting, by the condensed fluid that the instillation of suitable water dropper is not miscible, because capillary effect makes droplet retracts glomeration, and cooled and solidified and the pill made.
, primarily of the composition such as equipment, condensate tank of water dropper, heat-preserving equipment, control condensation temperature, there is complex structure in the existing apparatus preparing drop pill, uses the problem manufacturing processing inconvenience.
Summary of the invention
The object of the invention is to provide a kind of medicinal drop pill device and utilizes it to make the method for brain-benefiting and hair-blackening drop pill.
To achieve these goals, the technical solution used in the present invention is as follows:
A kind of medicinal drop pill device, comprise medicine liquid tank, medicine liquid tank top is provided with hot water inlet, medicine liquid tank bottom is provided with hot water outlet, and medicine liquid tank top is provided with medicinal liquid import, and medicine liquid tank bottom is provided with medicine liquid outlet, medicine liquid outlet connects water dropper by the ball pipeline that goes out with control valve, be provided with the cooled containers that coolant is housed below water dropper, go out outside ball pipeline and be set with condensing tube, condensing tube has the hot water inlet be connected with hot water outlet and the circulating water outlet be connected with hot water inlet.
Described medicinal drop pill device preferred version, medicine liquid tank comprises Inner tank and outer tank, and hot water inlet and hot water outlet are arranged on the outer sidewall of outer tank, and medicinal liquid import is arranged on Inner upper end, and medicine liquid outlet runs through Inner tank and outer tank.
Described medicinal drop pill device preferred version, is provided with agitating device in medicine liquid tank.
Described medicinal drop pill device preferred version, medicine liquid tank and condensing tube are high-boron-silicon glass.
Utilize medicinal drop pill device to make a method for brain-benefiting and hair-blackening drop pill, comprise the following steps:
A. Radix Rehmanniae extract makes: taking Radix Rehmanniae volume by volume concentration is 70% alcohol reflux, and be concentrated into every ml containing crude drug amount 5g, extracting solution reclaims ethanol;
B. Radix Polygoni Multiflori extract makes: taking Radix Polygoni Multiflori volume by volume concentration is 70% alcohol reflux, and be concentrated into every ml containing crude drug amount 5g, extracting solution reclaims ethanol;
C. Fructus Ligustri Lucidi extract makes: take Fructus Ligustri Lucidi, with soak by water, is concentrated into every ml containing crude drug amount 2.5g;
D. Herba Ecliptae extract makes: taking Herba Ecliptae, is 70% alcohol reflux with volume by volume concentration, and be concentrated into every ml containing crude drug amount 2.5g, extracting solution reclaims ethanol;
E. by the extracting solution of above steps according to weight ratio Radix Rehmanniae extract: Radix Polygoni Multiflori extract: Fructus Ligustri Lucidi extract: Herba Ecliptae extract=2:2:1:1 merges, and being concentrated into extractum relative density is 1.1-1.2;
F. extractum being mixed according to weight ratio 1:2 with Macrogol 4000, add in medicine liquid tank, add 85-90 DEG C of hot water while stirring and be incubated 40min and obtain fused solution, connecting water dropper instillation cooled containers through going out ball pipeline.
Beneficial effect of the present invention:
Medicinal drop pill device, injects hot water between medicine liquid tank Inner tank and outer tank, and spice placed by Inner tank, after going out ball pipeline, make finished product through cooled containers, easy to operate; Overall structure is simple, easily produces; Medicinal drop pill device is utilized to make brain-benefiting and hair-blackening drop pill, can YIN nourishing supplementing the brain, nourish blood black hair, product good effect.
Accompanying drawing explanation
Fig. 1 structural representation of the present invention.
1. outer tanks in figure, 2. Inner tank, 3. agitating device, 4. hot water outlet, 5. medicine liquid outlet, 6. control valve, 7. hot water inlet, 8. go out ball pipeline, 9. condensing tube, 10. water dropper, 11. cooled containers, 12. hot water inlets, 13. circulating water outlets, 14. medicinal liquid imports.
Detailed description of the invention
In conjunction with the accompanying drawing in the embodiment of the present invention, do describe clearly and completely further the present invention, described embodiment is only the present invention's part embodiment, instead of whole embodiments.
With reference to accompanying drawing 1, a kind of medicinal drop pill device, comprise medicine liquid tank, medicine liquid tank top is provided with hot water inlet 12, medicine liquid tank bottom is provided with hot water outlet 4, medicine liquid tank top is provided with medicinal liquid import 14, medicine liquid tank bottom is provided with medicine liquid outlet 5, medicine liquid outlet 5 connects water dropper 10 by the ball pipeline 8 that goes out with control valve 6, the cooled containers 11 that coolant is housed is provided with below water dropper 10, go out outside ball pipeline 8 and be set with condensing tube 9, condensing tube 9 has the hot water inlet 7 be connected with hot water outlet 4 and the circulating water outlet 13 be connected with hot water inlet 12.
In the present embodiment, medicine liquid tank comprises Inner tank 2 and outer tank 1, and hot water inlet 12 and hot water outlet 4 are arranged on the outer sidewall of outer tank 1, and medicinal liquid import 14 is arranged on Inner tank 2 top, and medicine liquid outlet 5 runs through Inner tank 2 and outer tank 1.
In the present embodiment, in medicine liquid tank, be provided with agitating device 3, reaction can be made even.
In the present embodiment, medicine liquid tank and condensing tube 9 are high-boron-silicon glass, ensure that safety and sanitation, can not bring impurity into.
Utilize medicinal drop pill device to make a method for brain-benefiting and hair-blackening drop pill, comprise the following steps:
A. Radix Rehmanniae extract makes: taking Radix Rehmanniae volume by volume concentration is 70% alcohol reflux, and be concentrated into every ml containing crude drug amount 5g, extracting solution reclaims ethanol;
B. Radix Polygoni Multiflori extract makes: taking Radix Polygoni Multiflori volume by volume concentration is 70% alcohol reflux, and be concentrated into every ml containing crude drug amount 5g, extracting solution reclaims ethanol;
C. Fructus Ligustri Lucidi extract makes: take Fructus Ligustri Lucidi, with soak by water, is concentrated into every ml containing crude drug amount 2.5g;
D. Herba Ecliptae extract makes: taking Herba Ecliptae, is 70% alcohol reflux with volume by volume concentration, and be concentrated into every ml containing crude drug amount 2.5g, extracting solution reclaims ethanol;
E. by the extracting solution of above steps according to weight ratio Radix Rehmanniae extract: Radix Polygoni Multiflori extract: Fructus Ligustri Lucidi extract: Herba Ecliptae extract=2:2:1:1 merges, and being concentrated into extractum relative density is 1.1-1.2;
F. extractum being mixed according to weight ratio 1:2 with Macrogol 4000, add in medicine liquid tank, add 85-90 DEG C of hot water while stirring and be incubated 40min and obtain fused solution, connecting water dropper instillation cooled containers through going out ball pipeline.
Above only describes ultimate principle of the present invention and preferred implementation, those skilled in the art can make many changes and improvements according to foregoing description, and these changes and improvements should belong to protection scope of the present invention.

Claims (5)

1. a medicinal drop pill device, it is characterized in that: comprise medicine liquid tank, medicine liquid tank top is provided with hot water inlet, medicine liquid tank bottom is provided with hot water outlet, and medicine liquid tank top is provided with medicinal liquid import, and medicine liquid tank bottom is provided with medicine liquid outlet, medicine liquid outlet connects water dropper by the ball pipeline that goes out with control valve, be provided with the cooled containers that coolant is housed below water dropper, go out outside ball pipeline and be set with condensing tube, condensing tube has the hot water inlet be connected with hot water outlet and the circulating water outlet be connected with hot water inlet.
2. medicinal drop pill device according to claim 1, it is characterized in that: medicine liquid tank comprises Inner tank and outer tank, hot water inlet and hot water outlet are arranged on the outer sidewall of outer tank, and medicinal liquid import is arranged on Inner upper end, and medicine liquid outlet runs through Inner tank and outer tank.
3. medicinal drop pill device according to claim 1, is characterized in that: be provided with agitating device in medicine liquid tank.
4. medicinal drop pill device according to claim 1 or 2 or 3, is characterized in that: medicine liquid tank and condensing tube are high-boron-silicon glass.
5. utilize medicinal drop pill device described in claim 1 or 2 or 3 to make a method for brain-benefiting and hair-blackening drop pill, it is characterized in that, comprise the following steps:
A. Radix Rehmanniae extract makes: taking Radix Rehmanniae volume by volume concentration is 70% alcohol reflux, and be concentrated into every ml containing crude drug amount 5g, extracting solution reclaims ethanol;
B. Radix Polygoni Multiflori extract makes: taking Radix Polygoni Multiflori volume by volume concentration is 70% alcohol reflux, and be concentrated into every ml containing crude drug amount 5g, extracting solution reclaims ethanol;
C. Fructus Ligustri Lucidi extract makes: take Fructus Ligustri Lucidi, with soak by water, is concentrated into every ml containing crude drug amount 2.5g;
D. Herba Ecliptae extract makes: taking Herba Ecliptae, is 70% alcohol reflux with volume by volume concentration, and be concentrated into every ml containing crude drug amount 2.5g, extracting solution reclaims ethanol;
E. by the extracting solution of above steps according to weight ratio Radix Rehmanniae extract: Radix Polygoni Multiflori extract: Fructus Ligustri Lucidi extract: Herba Ecliptae extract=2:2:1:1 merges, and being concentrated into extractum relative density is 1.1-1.2;
F. extractum being mixed according to weight ratio 1:2 with Macrogol 4000, add in medicine liquid tank, add 85-90 DEG C of hot water while stirring and be incubated 40min and obtain fused solution, connecting water dropper instillation cooled containers through going out ball pipeline.
CN201510983386.7A 2015-12-24 2015-12-24 Medical dropping pill device and method for preparing brain strengthening and hair blacking dropping pills with same Pending CN105411855A (en)

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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1748668A (en) * 2005-07-13 2006-03-22 余清 Small quick multifunctional Chinese medicine preparation making machine
CN2794514Y (en) * 2005-05-11 2006-07-12 闵金杆 Heater for dripping tank of dripping pill machine
CN1824016A (en) * 2005-12-15 2006-08-30 北京阜康仁生物制药科技有限公司 Compound flowery knotweed and rehmannia preparation and its manufacturing method
US20080038334A1 (en) * 2006-08-08 2008-02-14 John Zazula Method for producing and a system for cooling a hot-filled softgel capsule
CN201186050Y (en) * 2008-04-30 2009-01-28 烟台开发区博森制药机械有限公司 Pill dripping machine for experiment
CN102228669A (en) * 2011-06-14 2011-11-02 重庆顶尚生物制品有限责任公司 Traditional Chinese medicine preparation for treating alopecia and preparation method thereof
CN204033788U (en) * 2014-09-01 2014-12-24 覃国萍 A kind of drop pill device making large dripping pillar
CN205322810U (en) * 2015-12-24 2016-06-22 山东省化工研究院 Medicinal dripping pill device

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN2794514Y (en) * 2005-05-11 2006-07-12 闵金杆 Heater for dripping tank of dripping pill machine
CN1748668A (en) * 2005-07-13 2006-03-22 余清 Small quick multifunctional Chinese medicine preparation making machine
CN1824016A (en) * 2005-12-15 2006-08-30 北京阜康仁生物制药科技有限公司 Compound flowery knotweed and rehmannia preparation and its manufacturing method
US20080038334A1 (en) * 2006-08-08 2008-02-14 John Zazula Method for producing and a system for cooling a hot-filled softgel capsule
CN201186050Y (en) * 2008-04-30 2009-01-28 烟台开发区博森制药机械有限公司 Pill dripping machine for experiment
CN102228669A (en) * 2011-06-14 2011-11-02 重庆顶尚生物制品有限责任公司 Traditional Chinese medicine preparation for treating alopecia and preparation method thereof
CN204033788U (en) * 2014-09-01 2014-12-24 覃国萍 A kind of drop pill device making large dripping pillar
CN205322810U (en) * 2015-12-24 2016-06-22 山东省化工研究院 Medicinal dripping pill device

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Application publication date: 20160323