CN104305177A - Preparation method of poria cocos qi tonifying chewable tablet - Google Patents

Preparation method of poria cocos qi tonifying chewable tablet Download PDF

Info

Publication number
CN104305177A
CN104305177A CN201410516999.5A CN201410516999A CN104305177A CN 104305177 A CN104305177 A CN 104305177A CN 201410516999 A CN201410516999 A CN 201410516999A CN 104305177 A CN104305177 A CN 104305177A
Authority
CN
China
Prior art keywords
poria cocos
preparation
tonifying
chewable tablets
ginseng
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201410516999.5A
Other languages
Chinese (zh)
Inventor
吴克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jiangsu Qilikang Skin Pharmaceutical Co Ltd
Original Assignee
Jiangsu Qilikang Skin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jiangsu Qilikang Skin Pharmaceutical Co Ltd filed Critical Jiangsu Qilikang Skin Pharmaceutical Co Ltd
Priority to CN201410516999.5A priority Critical patent/CN104305177A/en
Publication of CN104305177A publication Critical patent/CN104305177A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a preparation method of a poria cocos qi tonifying chewable tablet, belonging to the technical field of a traditional Chinese medicinal preparation. The preparation method comprises steps of preparing the following raw materials: poria cocos, ginseng, filler, a binding agent, a lubricant and a flavoring agent; decocting the poria cocos and the ginseng in water, heating and refluxing, decompressing and condensing filtrate, and cooling the filtrate; adding an ethanol water solution to an obtained decoction and uniformly stirring; standing for 4-8h, filtering and reserving supernatant, decompressing and condensing, and recovering ethanol; and uniformly mixing the filler, the binding agent, the lubricant and the flavoring agent with thick paste, granulating, drying and tabletting to obtain the chewable tablet. The poria cocos chewable tablet disclosed by the invention is easy to carry and take, and is high in content of active ingredients.

Description

A kind of preparation method of Poria cocos tonifying Qi chewable tablets
 
Technical field
The present invention relates to a kind of preparation method of Poria cocos tonifying Qi chewable tablets, belong to technical field of traditional Chinese medicine preparation.
 
Background technology
Food therapy is the important component part of traditional Chinese therapeutics, and ancient Chinese medicine doctor is under the guidance of this principle, and in the process of actual clinical prescriptions, normal medicine and food blendings uses, and medicine food is double to be executed, convenient, safe, effective.
Tonifying Qi, also known as beneficial gas.Refer to the method having tonifying Qi drug therapy syndrome of qi deficiency.Lung governing qi, the gas of main the whole body vital organs of the human body; Middle burnt taste by Na Shuigu, the strong fortune of temper, qi and bloodization is given birth to, therefore the deficiency of vital energy many to lung, spleen two is dirty relevant.Lung Qi deficiency is with deficiency of QI with disinclination to talk, and syndrome characterized by dyspnea easily, is afraid of that wind spontaneous perspiration is primary symptom; Spleen-Qi Deficiency is swollen, tired with gastral cavity abdomen void, and poor appetite, stool diarrhea is primary symptom.Available Yupingfeng San is mended and is defended gas, admittedly show arrest sweating; With Sijunzi Tang, Buzhong Yiqi Tang bowl spares gas, help strong fortune.Common drug has ginseng, the Radix Astragali, Radix Codonopsis, the bighead atractylodes rhizome, Chinese yam, Radix Glycyrrhizae etc.
The Poria cocos thoughts of returning home; Spleen; Lung; Kidney channel effect eliminating dampness and diuresis; Strengthening the spleen and stomach; Antitoxic heart-soothing and sedative (classify: sharp water medicine by effect; Diuretics with the action of eliminating dampness) cure mainly difficult urination; Oedema turgor; Phlegm and retained fluid is coughed inverse; Vomiting; Insufficiency of the spleen food is few; Have loose bowels; Palpitation and restlessness; Insomnia forgetfulness; Seminal emission gonorrhoea " book on Chinese herbal medicine is looked for the truth ": Poria cocos enters four monarchs, then assistant ginseng art is wet to ooze spleen man, enters Six-element, then makes rhizoma alismatis with after row kidney heresy, the most Li Shui dehumidifying key medicine.Invigorating the spleen said by book, namely water go and spleen from strong meaning also.And water both went, then urine was from opening, and be equipped with the worry of the retention of urine, water goes, and interior wetting disappears, is equipped with the meaning that urine is common.Gu Shui goes, and chest diaphragm is comforted oneself and ties pain dysphoria and do not do, and water goes, and body fluid is spontaneous and bitter taste tongue is dry knows.
Disclose a kind of air making-up and spleen enlivening Chinese medicine in patent CN101194991, be prepared from by the raw material of following weight ratio: Radix Angelicae Sinensis 6-8%; Grow radix paeoniae alba 6-8%; Ligusticum wallichii 2.5-3.5%; Large cultivated land 9-11%; Fruit of Chinese magnoliavine 4-5%; Fruit of Chinese wolfberry 6-8%; Raspberry 6-8%; Seed of Chinese dodder 6-8%; Fruit of Cherokee rose 6-8%; Glossy privet 6-8% processed; Eclipta 6-8%; Semen astragali complanati 6-8%; Radix Codonopsis 9-11%; Chinese yam rhizome 6-8%.This qi-invigorating herb needs decoction, is not suitable for the rhythm of life of current people.
 
Summary of the invention
The object of the invention is: provide a kind of and be applicable to high rhythm of life, be convenient to the tonifying Qi food therapeutic health taken, propose a kind of preparation method of Poria cocos tonifying Qi chewable tablets.
Technical scheme:
A preparation method for Poria cocos tonifying Qi chewable tablets, comprises the steps:
1st step, by weight, be on the waiting list following raw material, 20 ~ 30 parts, Poria cocos, ginseng 2 ~ 4 parts, filler 2 ~ 4 parts, 1 ~ 3 part, adhesive, lubricant 0.1 ~ 0.3 part, flavouring 1 ~ 2 part;
2nd step, get Poria cocos and ginseng, boiling, amount of water is 6 ~ 9 times of Poria cocos and ginseng gross weight, adds hot reflux, decocts 2 ~ 4 hours, by filtrate reduced in volume, is 1.20 ~ 1.22, lets cool to the relative density at 80 DEG C;
3rd step, in the decocting liquid of the 2nd step gained, add the ethanol water of 4 ~ 6 times of Poria cocos and ginseng gross weight, stir evenly; Leave standstill 4 ~ 8 hours, leaching supernatant, reduced pressure concentration, reclaiming ethanol, is the thick paste of 1.29 ~ 1.35 to the relative density at 80 DEG C;
4th step, separately get filler, adhesive, lubricant, flavouring, mix with thick paste, granulate, dry, compressing tablet is made.
Described filler is sweet mellow wine or sorbierite.
Described adhesive is Hydroxypropyl methylcellulose.
Described lubricant is dolomol.
Described flavouring is selected from maltitol, Sucralose, xylitol.
The mass concentration of described ethanol water is 60 ~ 90%.
Described Poria cocos is through yellow rice wine.
 
beneficial effect
Poria cocos chewable tablets provided by the invention, be easy to carry about with one and take, active constituent content is high.
 
Detailed description of the invention
 
embodiment 1
A preparation method for Poria cocos tonifying Qi chewable tablets, comprises the steps:
1st step, be on the waiting list following raw material, Poria cocos 20Kg, ginseng 2Kg, filler 2Kg, adhesive 1Kg, lubricant 0.1Kg, flavouring 1 ~ 2Kg;
2nd step, get Poria cocos and ginseng, boiling, amount of water is 6 times of Poria cocos and ginseng gross weight, adds hot reflux, decocts 2 hours, by filtrate reduced in volume, is 1.20, lets cool to the relative density at 80 DEG C;
3rd step, in the decocting liquid of the 2nd step gained, add the ethanol water of 4 times of Poria cocos and ginseng gross weight, stir evenly; Leave standstill 4 hours, leaching supernatant, reduced pressure concentration, reclaiming ethanol, is the thick paste of 1.29 to the relative density at 80 DEG C;
4th step, separately get filler, adhesive, lubricant, flavouring, mix with thick paste, granulate, dry, compressing tablet is made.
Described filler is sweet mellow wine, and adhesive is Hydroxypropyl methylcellulose, and lubricant is dolomol, and flavouring is xylitol, and the mass concentration of ethanol water is 70%.
 
embodiment 2
A preparation method for Poria cocos tonifying Qi chewable tablets, comprises the steps:
1st step, be on the waiting list following raw material, Poria cocos 30Kg, ginseng 4Kg, filler 4Kg, adhesive 3Kg, lubricant 0.3Kg, flavouring 2Kg;
2nd step, get Poria cocos and ginseng, boiling, amount of water is 9 times of Poria cocos and ginseng gross weight, adds hot reflux, decocts 4 hours, by filtrate reduced in volume, is 1.22, lets cool to the relative density at 80 DEG C;
3rd step, in the decocting liquid of the 2nd step gained, add the ethanol water of 6 times of Poria cocos and ginseng gross weight, stir evenly; Leave standstill 8 hours, leaching supernatant, reduced pressure concentration, reclaiming ethanol, is the thick paste of 1.35 to the relative density at 80 DEG C;
4th step, separately get filler, adhesive, lubricant, flavouring, mix with thick paste, granulate, dry, compressing tablet is made.
Described filler is sweet mellow wine, and adhesive is Hydroxypropyl methylcellulose, and lubricant is dolomol, and flavouring is xylitol, and the mass concentration of ethanol water is 70%.
 
embodiment 3
A preparation method for Poria cocos tonifying Qi chewable tablets, comprises the steps:
1st step, be on the waiting list following raw material, Poria cocos 25Kg, ginseng 3Kg, filler 3Kg, adhesive 2Kg, lubricant 0.2Kg, flavouring 1Kg;
2nd step, get Poria cocos and ginseng, boiling, amount of water is 7 times of Poria cocos and ginseng gross weight, adds hot reflux, decocts 3 hours, by filtrate reduced in volume, is 1.21, lets cool to the relative density at 80 DEG C;
3rd step, in the decocting liquid of the 2nd step gained, add the ethanol water of 5 times of Poria cocos and ginseng gross weight, stir evenly; Leave standstill 6 hours, leaching supernatant, reduced pressure concentration, reclaiming ethanol, is the thick paste of 1.32 to the relative density at 80 DEG C;
4th step, separately get filler, adhesive, lubricant, flavouring, mix with thick paste, granulate, dry, compressing tablet is made.
Described filler is sweet mellow wine, and adhesive is Hydroxypropyl methylcellulose, and lubricant is dolomol, and flavouring is xylitol, and the mass concentration of ethanol water is 70%.
 
embodiment 4
To be with the difference of embodiment 3: Poria cocos is through yellow rice wine.The method concocted is: be positioned over by Poria cocos in container, add yellow rice wine and Poria cocos is just infiltrated, and keep 4 ~ 8 hours under normal temperature, unnecessary yellow rice wine is removed in press filtration, then after Poria cocos is dried.
A preparation method for Poria cocos tonifying Qi chewable tablets, comprises the steps:
1st step, be on the waiting list following raw material, yellow rice wine Poria cocos 25Kg, ginseng 3Kg, filler 3Kg, adhesive 2Kg, lubricant 0.2Kg, flavouring 1Kg;
2nd step, get Poria cocos and ginseng, boiling, amount of water is 7 times of yellow rice wine Poria cocos and ginseng gross weight, adds hot reflux, decocts 3 hours, by filtrate reduced in volume, is 1.21, lets cool to the relative density at 80 DEG C;
3rd step, in the decocting liquid of the 2nd step gained, add the ethanol water of 5 times of yellow rice wine Poria cocos and ginseng gross weight, stir evenly; Leave standstill 6 hours, leaching supernatant, reduced pressure concentration, reclaiming ethanol, is the thick paste of 1.32 to the relative density at 80 DEG C;
4th step, separately get filler, adhesive, lubricant, flavouring, mix with thick paste, granulate, dry, compressing tablet is made.
Described filler is sweet mellow wine, and adhesive is Hydroxypropyl methylcellulose, and lubricant is dolomol, and flavouring is xylitol, and the mass concentration of ethanol water is 70%.
 
reference examples 1
Be with the difference of embodiment 3: do not add ginseng.
A preparation method for Poria cocos tonifying Qi chewable tablets, comprises the steps:
1st step, be on the waiting list following raw material, yellow rice wine Poria cocos 25Kg, filler 3Kg, adhesive 2Kg, lubricant 0.2Kg, flavouring 1Kg;
2nd step, get Poria cocos and ginseng, boiling, amount of water is 7 times of Poria cocos gross weight, adds hot reflux, decocts 3 hours, by filtrate reduced in volume, is 1.21, lets cool to the relative density at 80 DEG C;
3rd step, in the decocting liquid of the 2nd step gained, add the ethanol water of 5 times of Poria cocos gross weight, stir evenly; Leave standstill 6 hours, leaching supernatant, reduced pressure concentration, reclaiming ethanol, is the thick paste of 1.32 to the relative density at 80 DEG C;
4th step, separately get filler, adhesive, lubricant, flavouring, mix with thick paste, granulate, dry, compressing tablet is made.
Described filler is sweet mellow wine, and adhesive is Hydroxypropyl methylcellulose, and lubricant is dolomol, and flavouring is xylitol, and the mass concentration of ethanol water is 70%.
 
physical and chemical index detects
Measure polyoses content in the weight differential of the chewable tablets of preparation, hardness, friability, Poria cocos chewable tablets.Concrete assay method is as follows:
Hardness: get the chewable tablets of above-mentioned preparation in hardometer, manual pressure is burst apart to for test piece agent or occurs crackle, reads data on hardometer.As tablet can bear pressure at below 3kgf, then tablet hardness is defective.
Friability: chewable tablets about the 6.5g getting above-mentioned preparation in pallet, with hair-dryer blow away surface powder after precise weighing, then Poria cocos chewable tablets is placed in friability somascope rotate measure 4min.Take out Poria cocos chewable tablets, with precise weighing after the powder on method removing surface, weight must not reduce 2%, and must not occur fracture, be full of cracks and crushing phenomenon.
Polyoses content in Poria cocos chewable tablets:
Instrument: TU-1221 type spectrophotometer (Beijing application instrument plant).
The preparation of phenol reagent: take phenol 4g, 100 ml that add water make dissolving, in brown bottle, obtain the phenol test solution that concentration is 4%.
The preparation of need testing solution: chewable tablets is ground to form fine powder, precision takes fine powder 5g, puts in round-bottomed flask, and add water 100 ml, refluxing extraction 2h, takes advantage of heat filtering, repeats extraction 2 times, with washing slag on a small quantity, after filtrate is concentrated, be transferred in the easy bottle of 100 ml, be diluted with water to scale; Getting dilution 2 ml again puts in sedimentator, adds 80% ethanol 10 ml centrifugal, 2500 r/min, take out the supernatant that inclines after 30 min, precipitation is moved in 50 ml volumetric flasks, be diluted with water to scale, shake up, precision measures liquid 1 ml and adds 1 ml water in tool plug test tube, adds 4% phenol 1.0 ml, mixing, add rapidly the concentrated sulfuric acid 7.0 ml, shake up, move to be incubated 30 min in 40 DEG C of water-baths after in ice-water bath, take out after placing 30 min.
The preparation of standard solution: precision takes DEXTROSE ANHYDROUS 60 mg that 105 DEG C are dried to constant weight, put in 100 ml measuring bottles, add water and make dissolving and be diluted to scale (containing DEXTROSE ANHYDROUS 0.6 mg in every 1ml), accurate this liquid 0 of absorption, 0.1, 1, 1.5, 2.0, 2.5, 3.0ml puts in 50 ml volumetric flasks respectively, add water to scale, shake up, standard liquid 2 ml of the above-mentioned each concentration of accurate absorption is in tool plug test tube, add 4% phenol 1.0 ml, mixing, add rapidly the concentrated sulfuric acid 7.0 ml, shake up, move to be incubated 30 min in 40 DEG C of water-baths after in ice-water bath, take out after placing 30 min.
Determined wavelength: 490 nm.
According to standard solution drawing standard curve, measure the polyoses content in test sample.
Result is as follows:
Every tablet chewable tablets is by 0.8g.
As can be seen from the table, containing more pachymaran in chewable tablets provided by the invention, by after carrying out wine processing to Poria cocos in embodiment 4, explicitly can reduce friability, and the extraction content of polysaccharide can be improved, and owing to not adding ginseng in reference examples, cause friability to increase to some extent, and also containing certain polysaccharide in ginseng, the polyoses content that result in reference examples is on the low side.

Claims (8)

1. a preparation method for Poria cocos tonifying Qi chewable tablets, is characterized in that, comprises the steps:
1st step, by weight, be on the waiting list following raw material, 20 ~ 30 parts, Poria cocos, ginseng 2 ~ 4 parts, filler 2 ~ 4 parts, 1 ~ 3 part, adhesive, lubricant 0.1 ~ 0.3 part, flavouring 1 ~ 2 part;
2nd step, get Poria cocos and ginseng, boiling, amount of water is 6 ~ 9 times of Poria cocos and ginseng gross weight, adds hot reflux, decocts 2 ~ 4 hours, by filtrate reduced in volume, is 1.20 ~ 1.22, lets cool to the relative density at 80 DEG C;
3rd step, in the decocting liquid of the 2nd step gained, add the ethanol water of 4 ~ 6 times of Poria cocos and ginseng gross weight, stir evenly; Leave standstill 4 ~ 8 hours, leaching supernatant, reduced pressure concentration, reclaiming ethanol, is the thick paste of 1.29 ~ 1.35 to the relative density at 80 DEG C;
4th step, separately get filler, adhesive, lubricant, flavouring, mix with thick paste, granulate, dry, compressing tablet is made.
2. the preparation method of Poria cocos tonifying Qi chewable tablets according to claim 1, is characterized in that: described filler is sweet mellow wine or sorbierite.
3. the preparation method of Poria cocos tonifying Qi chewable tablets according to claim 1, is characterized in that: described adhesive is Hydroxypropyl methylcellulose.
4. the preparation method of Poria cocos tonifying Qi chewable tablets according to claim 1, is characterized in that: described lubricant is dolomol.
5. the preparation method of Poria cocos tonifying Qi chewable tablets according to claim 1, is characterized in that: described flavouring is selected from maltitol, Sucralose, xylitol.
6. the preparation method of Poria cocos tonifying Qi chewable tablets according to claim 1, is characterized in that: the mass concentration of described ethanol water is 60 ~ 90%.
7. the preparation method of Poria cocos tonifying Qi chewable tablets according to claim 1, is characterized in that: the mass concentration of described ethanol water is 70%.
8. the preparation method of Poria cocos tonifying Qi chewable tablets according to claim 1, is characterized in that: described Poria cocos is through yellow rice wine.
CN201410516999.5A 2014-09-30 2014-09-30 Preparation method of poria cocos qi tonifying chewable tablet Pending CN104305177A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410516999.5A CN104305177A (en) 2014-09-30 2014-09-30 Preparation method of poria cocos qi tonifying chewable tablet

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410516999.5A CN104305177A (en) 2014-09-30 2014-09-30 Preparation method of poria cocos qi tonifying chewable tablet

Publications (1)

Publication Number Publication Date
CN104305177A true CN104305177A (en) 2015-01-28

Family

ID=52360612

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410516999.5A Pending CN104305177A (en) 2014-09-30 2014-09-30 Preparation method of poria cocos qi tonifying chewable tablet

Country Status (1)

Country Link
CN (1) CN104305177A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104886326A (en) * 2015-05-07 2015-09-09 曾剑妮 Poria cocos pieces and production method thereof
CN111870621A (en) * 2020-08-14 2020-11-03 夏荣全 Anticancer solid beverage with homology of medicine and food and preparation method thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102273575A (en) * 2011-08-26 2011-12-14 吉林紫鑫药业股份有限公司 Ginseng and tuckahoe cream and production process thereof
CN103053897A (en) * 2011-10-20 2013-04-24 北京以岭药业有限公司 Ginseng polysaccharide chewable tablet and preparation method thereof
KR20140074422A (en) * 2012-12-07 2014-06-18 주식회사 대화약품 Method for manufacturing functional pill product using silkworm
CN103960568A (en) * 2014-05-29 2014-08-06 延边长白山药业有限公司 Ginseng total saponins chewable tablet and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102273575A (en) * 2011-08-26 2011-12-14 吉林紫鑫药业股份有限公司 Ginseng and tuckahoe cream and production process thereof
CN103053897A (en) * 2011-10-20 2013-04-24 北京以岭药业有限公司 Ginseng polysaccharide chewable tablet and preparation method thereof
KR20140074422A (en) * 2012-12-07 2014-06-18 주식회사 대화약품 Method for manufacturing functional pill product using silkworm
CN103960568A (en) * 2014-05-29 2014-08-06 延边长白山药业有限公司 Ginseng total saponins chewable tablet and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104886326A (en) * 2015-05-07 2015-09-09 曾剑妮 Poria cocos pieces and production method thereof
CN111870621A (en) * 2020-08-14 2020-11-03 夏荣全 Anticancer solid beverage with homology of medicine and food and preparation method thereof

Similar Documents

Publication Publication Date Title
CN101347612B (en) Compound medicament for treating common cold cough and acute/chronic bronchitis, and preparation method thereof
CN104027566B (en) Jianer xiaoshi oral liquid and preparation process thereof
CN103800438B (en) Ligusticum wallichii tea modulator and preparation method thereof
CN103589578B (en) Radix Codonopsis wine and brewing method thereof
CN100588415C (en) Capsule for treating chronic bronchitis and its preparing method
CN107456513A (en) Chinese medicine composition with fat-reducing body shaping effect
CN103191298B (en) Traditional Chinese medicinal composition for treating blood group incompatibility haemolytic disease and preparation method thereof
CN103656072A (en) Traditional Chinese medicine composition for prompting pregnancy and preparation method thereof
CN104305177A (en) Preparation method of poria cocos qi tonifying chewable tablet
CN101406598B (en) Chinese medicine composite for treating diabetes and preparation method thereof
CN102327472A (en) Chinese herbal medicine for treating rectocele
CN104758736A (en) Blood-glucose-reducing traditional Chinese medicine composition and preparation method thereof
CN104043077A (en) Traditional Chinese medicine composition for tonifying qi and nourishing blood
CN103349707A (en) Method for preparing eight-treasure granules
CN1943756B (en) A Chinese traditional medicinal composition used for treatment of hypertension and its preparation method
CN103784771A (en) Traditional Chinese medicine composition has functions of anticoccidia, haemostasis and blood enriching, and antibiosis and antiphlogosis, and preparation method thereof
CN102327526B (en) Traditional Chinese medicine composition for lowering blood sugar
CN103055136A (en) Chinese herbal medicine for treating rheumatoid arthritis
CN107582613A (en) One seed ginseng stilbene chewable tablets and preparation method thereof
CN106983816A (en) A kind of medicine for merging chronic heart failure for maintenance hemodialysis patient and preparation method thereof
CN102309725B (en) Traditional Chinese medicine preparation for treating hepatitis B cirrhosis and preparation method
CN106806721A (en) The Chinese medicinal formulae and its product of a kind of qi-supplementing, spleen-invigorating, kidney-tonifying
CN103784735A (en) Chinese herbal medicine for treating rectocele
CN103041159A (en) Chinese herbal medicine for treating gastroptosis
CN111035710A (en) Traditional Chinese medicine for treating diabetes

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20150128

RJ01 Rejection of invention patent application after publication