EP1889907A4 - Nouvelle transférase de groupe aminé, gène codant celle-ci et procédé d'utilisation de celle-ci - Google Patents
Nouvelle transférase de groupe aminé, gène codant celle-ci et procédé d'utilisation de celle-ciInfo
- Publication number
- EP1889907A4 EP1889907A4 EP06746704A EP06746704A EP1889907A4 EP 1889907 A4 EP1889907 A4 EP 1889907A4 EP 06746704 A EP06746704 A EP 06746704A EP 06746704 A EP06746704 A EP 06746704A EP 1889907 A4 EP1889907 A4 EP 1889907A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- same
- amino group
- gene encoding
- novel amino
- group transferase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/001—Amines; Imines
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/002—Nitriles (-CN)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/008—Preparation of nitrogen-containing organic compounds containing a N-O bond, e.g. nitro (-NO2), nitroso (-NO)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2005149900 | 2005-05-23 | ||
PCT/JP2006/310170 WO2006126498A1 (fr) | 2005-05-23 | 2006-05-22 | Nouvelle transferase de groupe amine, gene codant celle-ci et procede d’utilisation de celle-ci |
Publications (3)
Publication Number | Publication Date |
---|---|
EP1889907A1 EP1889907A1 (fr) | 2008-02-20 |
EP1889907A4 true EP1889907A4 (fr) | 2008-07-02 |
EP1889907B1 EP1889907B1 (fr) | 2009-09-02 |
Family
ID=37451924
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP06746704A Active EP1889907B1 (fr) | 2005-05-23 | 2006-05-22 | Nouvelle transférase de groupe aminé, gène codant celle-ci et procédé d'utilisation de celle-ci |
Country Status (5)
Country | Link |
---|---|
US (2) | US8133705B2 (fr) |
EP (1) | EP1889907B1 (fr) |
JP (1) | JP4922929B2 (fr) |
DE (1) | DE602006008934D1 (fr) |
WO (1) | WO2006126498A1 (fr) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1818411A1 (fr) * | 2006-02-13 | 2007-08-15 | Lonza AG | Procédé pour la preparation d'amines chirales optiquement actives |
EP1897956A1 (fr) * | 2006-09-06 | 2008-03-12 | Lonza AG | Procédé de préparation d'amines optiquement actives par résolution optique en utilisant d'une oméga-transaminase bactérienne |
KR101489267B1 (ko) | 2007-12-27 | 2015-02-04 | 도오레 화인케미칼 가부시키가이샤 | 광학 활성 3-아미노피롤리딘염, 그 제조 방법 및 3-아미노피롤리딘의 광학 분할 방법 |
HUE052297T2 (hu) | 2009-01-08 | 2021-04-28 | Codexis Inc | Transzamináz polipeptidek |
ES2448816T3 (es) | 2009-02-26 | 2014-03-17 | Codexis, Inc. | Biocatalizadores de transaminasa |
US8921079B2 (en) | 2009-06-22 | 2014-12-30 | Codexis, Inc. | Transaminase reactions |
HUE038434T2 (hu) | 2010-06-17 | 2018-10-29 | Codexis Inc | Biokatalizátorok és módszerek (S)-3(1-aminoetil)-fenol szintéziséhez |
US8932836B2 (en) | 2010-08-16 | 2015-01-13 | Codexis, Inc. | Biocatalysts and methods for the synthesis of (1R,2R)-2-(3,4-dimethoxyphenethoxy)cyclohexanamine |
EP2623595B1 (fr) * | 2010-09-28 | 2016-11-02 | Kaneka Corporation | Nouvelle transaminase présentant une activité élevée vis-à-vis de l'acide glutamique, gène codant ladite transaminase, et sa méthode d'utilisation |
US9481870B2 (en) | 2010-09-28 | 2016-11-01 | Kaneka Corporation | Nucleic acid encoding a polypeptide having aminotransferase activity, vectors and host cells comprising the nucleic acid |
WO2012124639A1 (fr) | 2011-03-11 | 2012-09-20 | 株式会社カネカ | Aminotransférase modifiée, gène correspondant, et procédé de production de composé aminé optiquement actif utilisant un tel gène |
CN102731326B (zh) * | 2011-04-01 | 2014-07-23 | 安徽省科隆药物研究所 | 一种合成(s)-2-氨基-5-甲氧基-1,2,3,4-四氢萘盐酸盐的方法 |
CN106053657B (zh) * | 2016-07-01 | 2018-12-04 | 东北制药集团股份有限公司 | 一种采用高效液相色谱检测手性苯乙胺含量的方法 |
CN105987894B (zh) * | 2016-07-06 | 2019-03-05 | 天津大学 | 酶偶联核酸-银纳米的探针在检测d-氨基酸的应用 |
CN106018371B (zh) * | 2016-07-06 | 2019-02-15 | 天津大学 | 酶偶联核酸-银纳米探针 |
CN114277011B (zh) * | 2021-12-29 | 2024-02-06 | 凯莱英医药集团(天津)股份有限公司 | 转氨酶突变体及其应用 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002077183A2 (fr) * | 2001-03-21 | 2002-10-03 | Elitra Pharmaceuticals, Inc. | Identification de genes essentiels dans des microorganismes |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4950606A (en) * | 1989-06-22 | 1990-08-21 | Celgene Corporation | Enantiomeric enrichment and stereoselective synthesis of chiral amines |
JP3078137B2 (ja) * | 1992-12-15 | 2000-08-21 | 株式会社トクヤマ | ベンジルアミントランスアミナーゼ |
WO1997015682A1 (fr) * | 1995-10-23 | 1997-05-01 | Kaneka Corporation | Procede de production de composes amines actifs sur le plan optique |
JP4213771B2 (ja) | 1997-04-23 | 2009-01-21 | 株式会社カネカ | 光学活性アミノ化合物の製造方法 |
WO2000026351A1 (fr) * | 1998-10-30 | 2000-05-11 | Kaneka Corporation | (S)-α-PHENETHYLAMINE : TRANSAMINASE DE PYRUVATE |
JP3870690B2 (ja) * | 2000-09-01 | 2007-01-24 | 三菱化学株式会社 | 光学活性アミン類の製造方法 |
-
2006
- 2006-05-22 WO PCT/JP2006/310170 patent/WO2006126498A1/fr active Application Filing
- 2006-05-22 DE DE602006008934T patent/DE602006008934D1/de active Active
- 2006-05-22 EP EP06746704A patent/EP1889907B1/fr active Active
- 2006-05-22 US US11/920,842 patent/US8133705B2/en active Active
- 2006-05-22 JP JP2007517819A patent/JP4922929B2/ja active Active
-
2012
- 2012-01-27 US US13/360,196 patent/US8431378B2/en active Active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002077183A2 (fr) * | 2001-03-21 | 2002-10-03 | Elitra Pharmaceuticals, Inc. | Identification de genes essentiels dans des microorganismes |
Non-Patent Citations (2)
Title |
---|
HOLDEN MATTHEW T G ET AL: "Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, vol. 101, no. 39, 28 September 2004 (2004-09-28), pages 14240 - 14245, XP002399894, ISSN: 0027-8424 * |
See also references of WO2006126498A1 * |
Also Published As
Publication number | Publication date |
---|---|
JP4922929B2 (ja) | 2012-04-25 |
DE602006008934D1 (de) | 2009-10-15 |
US20100285544A1 (en) | 2010-11-11 |
US8431378B2 (en) | 2013-04-30 |
US8133705B2 (en) | 2012-03-13 |
JPWO2006126498A1 (ja) | 2008-12-25 |
EP1889907A1 (fr) | 2008-02-20 |
WO2006126498A1 (fr) | 2006-11-30 |
US20120164724A1 (en) | 2012-06-28 |
EP1889907B1 (fr) | 2009-09-02 |
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