EP1877407A1 - Imidazo(1,2-a)pyridin-derivate zur verwendung als peptiddeformylase-(pdf)-hemmer - Google Patents
Imidazo(1,2-a)pyridin-derivate zur verwendung als peptiddeformylase-(pdf)-hemmerInfo
- Publication number
- EP1877407A1 EP1877407A1 EP06742662A EP06742662A EP1877407A1 EP 1877407 A1 EP1877407 A1 EP 1877407A1 EP 06742662 A EP06742662 A EP 06742662A EP 06742662 A EP06742662 A EP 06742662A EP 1877407 A1 EP1877407 A1 EP 1877407A1
- Authority
- EP
- European Patent Office
- Prior art keywords
- group
- atom
- groups
- compounds according
- radicals
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Definitions
- heteroalkyl groups are groups of formulae R ⁇ O-Y 3 -, R ⁇ S-Y 3 -, R ⁇ N(R 1 O-Y 3 -, R ⁇ CO-Y 3 -, R a -O-CO-Y ⁇ R ⁇ CO-O-Y 3 -, R ⁇ CO-N(R 1 O-Y 3 -, R ⁇ N(R 1 O-CO-Y 3 -,
- heteroaralkyl refers to an aralkyl group as defined above, in which one or more (preferably 1, 2, 3 or 4) ring carbon atoms and/or carbon atoms are replaced by an oxygen, nitrogen, silicon, selenium, phosphorus, boron or sulfur atom (preferably oxygen, sulfur or nitrogen), i.e. it refers to groups which, in accordance with the above definitions, contain both aryl or heteroaryl, and alky!, alkeny!, alkinyl and/or heteroaiky! and/or cycloalkyl and/or heterocycloalkyl groups.
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102005019180 | 2005-04-25 | ||
PCT/EP2006/003765 WO2006114261A1 (en) | 2005-04-25 | 2006-04-24 | Imidazo(1,2-a)pyridine derivatives useful as peptide deformylase (pdf) inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
EP1877407A1 true EP1877407A1 (de) | 2008-01-16 |
Family
ID=36686088
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP06742662A Withdrawn EP1877407A1 (de) | 2005-04-25 | 2006-04-24 | Imidazo(1,2-a)pyridin-derivate zur verwendung als peptiddeformylase-(pdf)-hemmer |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1877407A1 (de) |
JP (1) | JP2008538776A (de) |
KR (1) | KR20080002866A (de) |
CN (1) | CN101166740B (de) |
AU (1) | AU2006239546B2 (de) |
BR (1) | BRPI0610842A2 (de) |
CA (1) | CA2606251A1 (de) |
MX (1) | MX2007013237A (de) |
RU (1) | RU2409575C2 (de) |
WO (1) | WO2006114261A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008027812A2 (en) | 2006-08-28 | 2008-03-06 | Forest Laboratories Holdings Limited | Imidazopyridine and imidazopyrimidine derivatives |
US8193214B2 (en) * | 2006-10-06 | 2012-06-05 | Boehringer Ingelheim International Gmbh | Chymase inhibitors |
AU2017366621B2 (en) * | 2016-11-28 | 2021-07-29 | Jiangsu Hengrui Medicine Co., Ltd. | Pyrazolo-heteroaryl derivative, preparation method and medical use thereof |
CN107245050B (zh) * | 2016-12-05 | 2019-10-25 | 徐州医科大学 | 香草醛异羟肟酸类衍生物及其应用 |
US11744824B2 (en) | 2020-09-15 | 2023-09-05 | 1ST Biotherapeutics, Inc. | 2-amino-3-carbonyl imidazopyridine and pyrazolopyridine compounds |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0717971A (ja) * | 1993-07-02 | 1995-01-20 | Takeda Chem Ind Ltd | イミダゾール誘導体、その製造法及び用途 |
US6118001A (en) * | 1996-08-07 | 2000-09-12 | Darwin Discovery, Ltd. | Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity |
AR029916A1 (es) * | 2000-05-05 | 2003-07-23 | Smithkline Beecham Corp | N-formil-n-hidroxi-ariloxi alquilaminas y metodos para tratar infecciones bacterianas |
UY27813A1 (es) * | 2002-05-31 | 2003-12-31 | Smithkline Beecham Corp | Inhibidores de la peptido-desformilasa |
AU2003296960A1 (en) * | 2002-12-11 | 2004-06-30 | Smithkline Beecham Corporation | Peptide deformylase inhibitors |
-
2006
- 2006-04-24 CN CN2006800140369A patent/CN101166740B/zh not_active Expired - Fee Related
- 2006-04-24 JP JP2008508132A patent/JP2008538776A/ja active Pending
- 2006-04-24 EP EP06742662A patent/EP1877407A1/de not_active Withdrawn
- 2006-04-24 BR BRPI0610842-3A patent/BRPI0610842A2/pt not_active IP Right Cessation
- 2006-04-24 AU AU2006239546A patent/AU2006239546B2/en not_active Ceased
- 2006-04-24 MX MX2007013237A patent/MX2007013237A/es not_active Application Discontinuation
- 2006-04-24 WO PCT/EP2006/003765 patent/WO2006114261A1/en active Application Filing
- 2006-04-24 KR KR1020077024436A patent/KR20080002866A/ko not_active Application Discontinuation
- 2006-04-24 CA CA002606251A patent/CA2606251A1/en not_active Abandoned
- 2006-04-24 RU RU2007143501/04A patent/RU2409575C2/ru not_active IP Right Cessation
Non-Patent Citations (1)
Title |
---|
See references of WO2006114261A1 * |
Also Published As
Publication number | Publication date |
---|---|
BRPI0610842A2 (pt) | 2010-07-27 |
RU2409575C2 (ru) | 2011-01-20 |
AU2006239546A1 (en) | 2006-11-02 |
CA2606251A1 (en) | 2006-11-02 |
CN101166740B (zh) | 2010-12-29 |
AU2006239546B2 (en) | 2010-04-15 |
RU2007143501A (ru) | 2009-06-10 |
WO2006114261A1 (en) | 2006-11-02 |
CN101166740A (zh) | 2008-04-23 |
MX2007013237A (es) | 2008-01-24 |
JP2008538776A (ja) | 2008-11-06 |
KR20080002866A (ko) | 2008-01-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP1877408A1 (de) | Imidazo[1,2-a]pyridin-derivate als peptid-deformylase-hemmer | |
WO2006114261A1 (en) | Imidazo(1,2-a)pyridine derivatives useful as peptide deformylase (pdf) inhibitors | |
EP1893574A2 (de) | Peptiddeformylase- (pdf-) inhibitoren 4 | |
ZA200502862B (en) | Novel compounds with antibacterial activity | |
RU2379284C2 (ru) | Новые биоизостеры актинонина | |
US20060122241A1 (en) | Novel macrocycles for the treatment of cancer diseases | |
US20060084614A1 (en) | Novel factor viia inhibiting compounds | |
DE102005026231A1 (de) | Peptid-Deformylase (PDF) Inhibitoren 3 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20071126 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC NL PL PT RO SE SI SK TR |
|
DAX | Request for extension of the european patent (deleted) | ||
17Q | First examination report despatched |
Effective date: 20100503 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20110726 |