EP1851135B2 - Vorrichtung zur ausgabe von fluiden, besonders arzneifluiden unter druck - Google Patents

Vorrichtung zur ausgabe von fluiden, besonders arzneifluiden unter druck Download PDF

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Publication number
EP1851135B2
EP1851135B2 EP06709317.9A EP06709317A EP1851135B2 EP 1851135 B2 EP1851135 B2 EP 1851135B2 EP 06709317 A EP06709317 A EP 06709317A EP 1851135 B2 EP1851135 B2 EP 1851135B2
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EP
European Patent Office
Prior art keywords
container
edge
variable volume
opening
sleeve
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EP06709317.9A
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English (en)
French (fr)
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EP1851135A1 (de
EP1851135B8 (de
EP1851135B1 (de
Inventor
Chris Nimmo
Olivier Bertaud
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Power Container Corp
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Power Container Corp
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Priority claimed from FR0501511A external-priority patent/FR2882037B1/fr
Application filed by Power Container Corp filed Critical Power Container Corp
Priority to PL06709317T priority Critical patent/PL1851135T5/pl
Publication of EP1851135A1 publication Critical patent/EP1851135A1/de
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Publication of EP1851135B8 publication Critical patent/EP1851135B8/de
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant for a product delivered by a propellant
    • B65D83/60—Contents and propellant separated
    • B65D83/62—Contents and propellant separated by membrane, bag, or the like

Definitions

  • the subject of the invention is a device of the type that is capable of delivering fluids, in particular medicinal fluids, under pressure.
  • fluids, and mainly liquids containing medicinal or cosmetic substances, or constituted by natural products that may be modified or adapted must be delivered under pressure for the needs of their use.
  • the fluid is delivered not under the action of a propellant but under the action of a mechanical stress which is exerted on a container in the form of a pocket or bag of variable volume and of cylindrical general shape with longitudinal folds, filled with the fluid to be delivered.
  • the mechanical stress under the action of which the fluid contained in the variable volume container is delivered under pressure, is exerted by a cylindrical sleeve of elastic material, and in particular a rubber with special elastic properties, which surrounds the bag-shaped or bag-shaped container and whose diameter is slightly greater than that of the variable-volume container when it is empty.
  • the sleeve in question is then put in place and the fluid to be delivered is introduced under pressure into the container which expands against the opposite action of the elastic sleeve whose compression force exerted on the container increases with the expansion thereof. following filling by the fluid to be delivered.
  • the bag-shaped or bag-shaped container is provided with a control for actuating a valve for delivery of the fluid, the assembly being disposed within a conventional container or container of the type used. in the aerosol industry, particularly in cosmetology.
  • a container of variable volume intended to be filled with the fluid to be delivered and also equipped with a control adapted to actuate a valve to allow the delivery of the fluid under pressure
  • a container of variable volume intended to be filled with the fluid to be delivered and also equipped with a control adapted to actuate a valve to allow the delivery of the fluid under pressure
  • an outer container capable to withstand high pressures, especially greater than 20 bar; this outer container is filled with a pressurized neutral gas, the empty variable volume container being in place, then the latter is filled with the fluid to be delivered by the introduction of the latter under a pressure sufficient to overcome the pressure exerted on the container by the neutral gas filling the outer container, which has the effect of further increasing the pressure of the neutral gas.
  • the stress exerted on the inner container of variable volume and by virtue of which the pressurized fluid can be delivered is therefore pneumatic in nature.
  • the object of the invention is, above all, to overcome the disadvantages of the prior art and to make available to the user a device of the kind in question free from the drawbacks of those which already exist.
  • the invention is defined by claim 1 the device according to the invention and adapted to deliver fluids, particularly medicated, under pressure, is characterized in that it comprises a container of variable volume in the form of pocket or bag of cylindrical general shape with longitudinal folds containing the pressurized fluid to be delivered and provided with a command for opening a valve for delivering said liquid, the assembly being disposed inside a container resistant to a high internal pressure and in particular greater than 20 bars, the inner volume of the latter container between its wall and the variable volume container being filled with a neutral gas under a pressure sufficient to exert on the container of variable volume a sufficient pneumatic stress to allow to deliver the fluid contained therein when the aforesaid valve allowing this delivery is actuated by the aforesaid command .
  • the outer container of the device of the invention is intended to contain a gas under pressure, it must therefore be able to withstand a pressure greater than 5 bar, preferably greater than 8 bar, more preferably greater than 12 bar and may even be capable of withstanding pressures above 20 bar.
  • variable volume container containing the fluid to be delivered and the pressure-resistant outer container are made of transparent materials, so that the user sees the fluid and can know at any time the filling state of the device. Similarly, any alteration of the fluid that would lead to a change in the appearance thereof (coloring, phase shift, etc.) can be detected by the user.
  • the invention also relates to other arrangements which are preferably used at the same time and which will be more explicitly discussed below.
  • the fixing sleeve M preferably made of aluminum or tin-plated steel or tinplate (steel having a layer of tin on each side).
  • the containers 1 and 4 are advantageously made of aluminum, polyethylene terephthalate, or tin-plated steel, or any other suitable synthetic material having similar properties.
  • the containers 1 and 4 can each be made using laminates, at least one of the constituent layers gives the laminate sufficient mechanical strength, another layer can confer gas barrier properties, including oxygen, nitrogen and / or carbon dioxide, and / or another layer that can confer chemical resistance properties vis-à-vis the fluid to be delivered.
  • a layer capable of imparting good mechanical strength properties may for example be made of polyethylene terephthalate or PET.
  • a layer capable of imparting good gas barrier properties may, for example, be made of nylon, especially nylon MXD6, of ethylene-vinylalcohol resin (or EVOH) or of silicon oxide.
  • a layer capable of imparting good chemical resistance properties may, for example, also be made of polyethylene terephthalate.
  • the container 1 can be made of a laminate of PET / Nylon / PET type, that is to say having an outer layer of polyethylene terephthalate, an intermediate layer of nylon and an inner layer, that is to say a layer intended to be in contact with the fluid to be delivered also, polyethylene terephthalate; it can also be made of a PET / EVOH / PET type laminate.
  • Such a PET / nylon / PET type material has the additional advantage of being transparent, which makes it particularly suitable for use in the context of the particular embodiment mentioned above, in which the inner container in the form of a pocket or variable volume bag and the outer container 4 are made of transparent materials.
  • the container 4 may be made of the same material. However, in view of the fact that this constituent material of this container is not in contact with the fluid to be delivered, it is entirely possible to use a two-layer laminate, for example polyethylene terephthalate and nylon.
  • Such a material lacking an internal layer conferring a chemical resistance may also be used for producing the container 1 insofar as the fluid to be delivered is chemically compatible with the other layers.
  • Such laminates can be made by using coextrusion or co-injection techniques using technologies such as those developed by KORTEC Inc. Ipswich, MA01938, USA.
  • a layer for example of silicon oxide
  • the layer thus deposited can be extremely thin, only a few microns thick.
  • the technology to be implemented is, for example, that developed by SIG CORPOPLAST Inc. under the name PLASMAX.
  • Such a layer may be deposited on a conventional monolayer material or on a laminate obtained by coextrusion or co-injection.
  • the inner container 1 and outer 4 of the sprayer according to the invention are made of a transparent synthetic material.
  • the invention proposes to overcome this disadvantage by proceeding as described below; it provides two solutions to the problem in question, these two solutions each involved at a different stage of the manufacture of the inner container 1.
  • This container of variable volume and which is in the form of a bag or bag of generally cylindrical shape with longitudinal folds, is prepared in two stages, respectively step A and step B.
  • the container of variable volume in the shape of a bag or bag of generally cylindrical shape is established, its wall being flat and in the second step or step B, this wall is given the longitudinal folds 2 which appear in particular on Figures 1 and 2 .
  • K blank made by injection inside a first mold
  • axial section at the figure 4 which is established in the synthetic material constituting the container to be prepared and which is in the form of a cylindrical tube closed at its end K1 and open at its other end, K2, said cylindrical tube being slightly conical (angled at vertex 1 ° to 5 °), the top of the cone at K1 having a protuberance K3; the protuberance K3 is designated by the term "door” and corresponds to the point of introduction of the pressurized fluid synthetic material into the mold.
  • This blank K is transferred by indexing into a second mold for the first step or step A of preparation of the inner container 1.
  • the second mold it is subjected to a mechanical elongation carried out using an element of the stylet type S introduced by the opening of the blank and whose end S1 exerts an axial mechanical effect on the bottom of the blank at its end K1; it is important that the protuberance K3 moves along the axis under the action of the stylet towards the center of the bottom of the blow mold; the aforesaid mechanical elongation is combined with a blow molding inside the second mold according to the process designated in the art by the term "stretch blow"; this second mold has the shape and the dimensions which make it possible to obtain directly the bag or bag of generally cylindrical shape constituting the container 1 which at this stage does not yet comprise the longitudinal folds 2.
  • the blank Under the effect of the pressure exerted by the compressed air, the blank extends in all directions.
  • the extension of its constituent material which is advantageously polyethylene terephthalate or PET, is accompanied by an increase in its resistance to fracture; this extension makes the thickness of the walls of the container thinner. It is this technique which is designated by the expression “biaxial blowing extension” or by “biaxial stretch elongation” or by “Stretch-Blow".
  • this first step or step A namely the element used for mechanical elongation and the second mold for the realization of blow molding or injection molding are marketed in particular by the company NISSEI ASB Company, 125 Westlake Parkway, Suite 120, ATLANTA , Georgia 30336 USA.
  • the bag is printed with a bag of generally cylindrical shape and whose wall is still flat, the longitudinal folds and ribs 2 appearing on the Figures 1 and 2 for example using a device of the type described in the patent US 4,701,120 , more particularly from line 50, column 1 to line 30, column 2.
  • This device comprises the elements which in the art are designated by “pallets” and thanks to which the folds and / or longitudinal ribs can be printed on the wall of the bag to the bag of generally cylindrical shape.
  • the folds or ribs 2 of the container 1 are made in two steps, the first consisting in making said container 1 blanks of ribs.
  • a mold which differs from those used in the prior art, in that the inner surface of its constituent wall against which is applied during blowing the constituent material of the future container 1, is arranged such that it comprises longitudinal ribs 20 whose shape results from the figure 5 which shows in section perpendicular to its axis XX, said mold used for blow molding, these longitudinal ribs 20 imprinting on the wall of the bag or bag of variable volume and generally cylindrical in shape of the container 1 longitudinal folds or ribs 21 which constitute drafts of future folds or ribs 2 and which are shown in FIG. figure 6 which is a sectional view perpendicular to the axis YY of the bag or bag of variable volume 1 at the outlet of the mold in question and before its introduction into the ply forming apparatus 2 implemented during the second step or step B.
  • the number of these blanks 21, generally 16, must be the same as the number of pallets of the device used in the second step or step B to make the container 1 comprise the longitudinal ribs 2.
  • the 16 blanks 21 comprising the bag or bag of variable volume obtained at the end of the first step or step A coincide with the parts of the device used in the second step or step B during which the 16 pallets of this device print to the bag or pocket of variable volume the definitive ribs 2.
  • This split ring 23 makes it possible to carry the bag or bag of variable volume inside the mechanism which conveys it to the folding head at which the ribs 2 are made from the blanks 21, previously formed by means of the conformation of the inner wall of the blow mold.
  • a mechanism may be envisaged comprising a pawl or stop actuated under the influence of a spring which ensures that when the pawl or abutment is at the level of the cut of the split ring, it enters this cut to block the rotation bag or pouch of variable volume thus ensuring the desired positioning.
  • the support that holds the bag or bag of variable volume inside the plug head is designed so that it allows this rotation by means of a pneumatic rotary motor which, under the effect of a control, rotates said bag or pouch inside the gripper head to the position in which the pawl or stop engages the cutout provided for in the split ring to stop the bag or pocket in the desired position.
  • the folding of the container 1 is carried out so that it resumes its initial shape after all the fluid to be delivered has been used.
  • this sleeve R is made of transparent elastic synthetic material and has at its inner surface longitudinal ribs primer 25 parallel to the axis ZZ in the same number as the longitudinal folds or ribs 2 formed by the container 1 of variable shape so that the rib primers comprised by the cylindrical sleeve are respectively positioned respectively between two ribs 2 of the bag or pouch of variable volume 1.
  • the sleeve R remains permanently in position on the container 1.
  • the container 1 Due to the presence of the sleeve R, the container 1 is folded in a regular manner, returning the container to its original shape once all the fluid to be delivered has been used.
  • the figure 3 shows in detail the constituent parts of the device according to the invention according to the present advantageous embodiment.
  • the sealing on the one hand, at the crimping of the fixing sleeve M on the extension E2 near the edge 3 of the opening of the container 1, is provided by a seal 8 of elastomeric material, in particular rubber and, on the other hand, at the crimping of the same sleeve on the edge 5 of the opening of the container 4 by a seal 9 established in the same material as the gasket 8.
  • the seal 9 in the case where the container 4 is made of a material having sufficient elasticity characteristics, for example polyethylene terephthalate or any similar synthetic material.
  • the tightness of the packaging will then be ensured directly during crimping between the edge 5 of the container and the sleeve M because of the elastic properties of the material.
  • the absence of seal allows a reduction of the cost.
  • the crimping of the sleeve M on the end of the extension E 2 of the container 1 is made possible by an outer rim 10 provided at its end.
  • the container 1 may be surrounded by an elastic cylindrical sleeve 11 which is advantageously made of synthetic material, in particular polyvinylethylene, the function of which is to protect the container 1.
  • the sleeve M has a central circular opening whose edge is shown at 12.
  • the control C which is in the form of a push button, has a general shape of hat-shaped case, as shown figure 3 advantageously made of rigid synthetic material, in particular of high density polyethylene; it comprises an axial tube 13 with an internal axial duct 13a, which, on the one hand, communicates at its upper end 13b with a duct 14 formed in the upper part C 1 of the control and connected to the tube 13 and, on the other hand, opens by its lower end 13c, when in place as shown in FIG. figure 3 on the device according to the invention, in the part E 2 of the container 1 through the opening 12 of the fixing sleeve M, the gasket 8 being arranged in such a way that it also seals with the tube 13 as visible.
  • control C is thus arranged and held in place on the end E 2 of the container 1 by positioning the tube 13 in the edge opening 3 of the container 1 as shown.
  • the end 13c of the tube 13 is supported on a valve constituted by a cup-shaped element having a bottom 15a and a wall 15b; at the end 13c, the tube 13 has an opening or notch 13d.
  • the element 17 has an axial opening 17c for communicating the interior of the container 1 with the interior of the space delimited by the element 17.
  • the fluid under pressure contained in the container 1 can then pass between the free edge of the wall 15b and the gasket 8 towards the inside of the cup and by the notch 13d provided at the end 13c of the tube 13 in the axial duct 13a and then through the conduit 14 to the outside in the desired form.
  • the container 1, on which the fixing sleeve M has been attached after placing the gasket 8, is preferably emptied of most of the air contained therein.
  • the assembly is then fixed, after placing the seal 9, by crimping on the outer container 4 in which the container 1 is housed, before being introduced into the volume between the wall of the container 4 and the surface external container 1 of air or pressurized neutral gas in an amount such that the pressure reaches a value preferably between about 1.5 and about 3.5 bar, the precise value chosen depending on the nature of the fluid to be delivered.
  • a suitable tool for example a degassing and crimping head of the type marketed by Pamasol Willi Maeder AG, Driesbuelstrasse 2, CH-8808 Pfaffikon , SZ Switzerland under the name "UTC Head”.
  • This tool makes it possible to seal the upper surface of the container 4 and slightly raises the sleeve M, using a vacuum connection to suck the sleeve into a seat, and to allow the introduction under pressure of a neutral gas or compressed air.
  • the sleeve M is pressed on the edge 5 of the container 4 and the head and crimping is performed between the sleeve M and the container 4. During this operation, sufficient pressure is maintained by the head to compress the seal 9 and thus ensure a good seal between the sleeve M and the container 4.
  • the container 1 is then filled with the fluid intended to be delivered under pressure.
  • This dosing unit generally comprises a volumetric dosing device under high pressure, and a filling nozzle. After crimping the sleeve M on the container 4, the assembly is positioned under a filling nozzle which is part of the conditioning unit and the nozzle is actuated to descend and seal on the sleeve. An adapter seals on the upper part 12 of the sleeve and the fluid is introduced under pressure through the valve 15 to fill the container 1.
  • the pressure of the air or neutral gas between the wall of the container 4 and the container 1 increases to generally reach a value between about 4 and about 10 bar, the precise value chosen being a function of the nature of the fluid to be delivered.
  • Control C is then put in place and the device according to the invention is ready for use.

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  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Filling Or Discharging Of Gas Storage Vessels (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Jellies, Jams, And Syrups (AREA)

Claims (11)

  1. Vorrichtung, die zur Abgabe von unter Druck stehenden Fluiden, insbesondere medikamentösen Fluiden, geeignet ist, dadurch gekennzeichnet, dass sie einen Behälter (1) mit variablem Volumen in Form eines Beutels oder einer Tasche mit im Allgemeinen zylindrischer Form mit Längsfalten (2) umfasst, der das abzugebende, unter Druck stehende Fluid enthält und mit einer Bedienungsvorrichtung (C) ausgestattet ist, die das Öffnen eines Ventils (15a, 15b) zur Abgabe der Flüssigkeit ermöglicht, wobei das Ganze im Inneren eines Behälters (4) angeordnet ist, der einem erhöhten Innendruck, insbesondere von über 20 bar, gegenüber beständig ist, wobei das Innenvolumen des letzteren Behälters, das zwischen seiner Wandung und dem Behälter mit variablem Volumen enthalten ist, mit einem neutralen Gas gefüllt ist, das unter ausreichendem Druck steht, um auf den Behälter mit variablem. Volumen eine ausreichende pneumatische Einengung auszuüben, um die Abgabe des Fluids, das Letzterer enthält, zu ermöglichen, wenn das Ventil, das diese Abgabe ermöglicht, durch die Bedienungsvorrichtung (C) betätigt wird, das Behälter (1) mit variablem Volumen ist in einem Stück von einem bi-axial Blasformen Verfahren erzeugt von einem Vor-form von Einspritzung produziert, und an einem seiner Enden (E1) geschlossen ist und an seinem anderen Ende eine Randöffnung (3) aufweist, die von einer zylindrischen Verlängerung (E2) getragen ist,
    - der Aussenbehälter (4), der ebenfalls zylindrisch ist und eine Randöffnung (5) umfasst, wobei in seinem Inneren der Behälter (1) mit variablem Volumen angeordnet ist,
    die Vorrichtung weiter enthält eine Befestigungsmuffe (M), die die Behälter (1, 4) miteinander verbindet und einen Umfang oder Rand (M1) und eine kreisförmige, axiale Randöffnung (12) umfasst,
    - die Bedienungsvorrichtung (C), die einen Druckknopf bildet und über der Öffnung des Behälters (1) mit variablem Volumen angeordnet ist,
    die Befestigungsmuffe (M) mit ihrem Umfang (M1) über dem Rand (5) des äusseren Behälters (4) gecrimpt ist und mit ihrem Mittelabschnitt, der die axiale Randöffnung (12) umfasst, über der Verlängerung (E2) in der Nähe des Rands (3) gecrimpt ist, einerseits auf der Höhe der Crimpung der Befestigungsmuffe (M) auf der Verlängerung (E2) in der Nähe des Rands (3) der Öffnung des Behälters (1) mit variablem Volumen, durch eine Dichtung (8) aus einem Elastomermaterial gebildet ist andererseits auf der Höhe der Crimpung derselben Muffe auf dem Rand (5) der äussere Öffnung des Behälters (4) durch eine Dichtung (9), oder wenn das äussere Behälters in einem material mit genügenden elastische Eigenschaften ausser dieser Dichtung aufweist, die Crimpung der Muffe (M) auf dem Ende der Verlängerung (E2) des Behälters (1) durch eine Aussenkrempe (10), die an deren Ende vorgesehen ist, ermöglicht ist.
  2. Vorrichtung nach Anspruch 1, dadurch gekennzeichnet dass der Höhe der Crimpung der Muffe auf dem Rand (5) der Öffnung des Behälters (4), die Dichtheit durch eine Dichtung (9), die aus dem gleichen Material wie die Dichtung (8) gebildet ist, sichergestellt ist.
  3. Vorrichtung nach einem der Ansprüche 1 und 2, dadurch gekennzeichnet,
    dass der Behälter (1) vorteilhafterweise aus Polyethylenterephthalat (PET) oder einem beliebigen anderen geeigneten synthetischen Material, das analoge Eigenschaften bietet, gebildet ist und dass die Muffe (M), die durch Crimpen auf dem Rand (3) befestigt ist, aus Aluminium oder verzinntem Stahl oder Weissblech (Stahl mit einer Zinnschicht an beiden Seiten) gebildet ist, wobei der Behälter (4) aus Aluminium, Polyethylenterephthalat oder verzinntem Stahl gebildet ist.
  4. Vorrichtung nach einem der Anspruche 1 bis 3, dadurch gekennzeichnet, dass die Bedienungseinrichtung (C), die in Form eines Druckknopfs vorliegt, im Allgemeinen eine Kapselform in der Form einer Kappe, vorzugsweise aus einem starren, synthetischen Material, insbesondere aus hochdichtem Polyethylen, aufweist und eine axiale Rohre (13) mit axialer Innenleitung (13a) umfasst, die einerseits an ihrem oberen Ende (13b) mit einer Leitung (14) kommuniziert, die im oberen Abschnitt (C1) der Bedienungsvorrichtung ausgebildet ist und mit der Röhre (13) verbunden ist, und andererseits an ihrem unteren Ende (13c), wenn sie auf der Vorrichtung angeordnet ist, in den Abschnitt (E2) des Behälters (1) mündet, indem sie durch die Öffnung (12) der Befestigungsmuffe (M) tritt, wobei die Dichtung (8) derart angeordnet ist, dass sie gleichermassen auch die Dichtheit zur Röhre (13) sicherstellt, wobei die Bedienungsvorrichtung (C) dank der Positionierung der Röhre (13) in der Randöffnung (3) des Behälters (1) über dem Ende (E2) des Behälters (1) angeordnet und an Ort und Stelle gehalten ist, wobei sich das Ende (13c) der Rohre (13) auf einem Ventil aufstützt, das von einem schalenförmigen Element, das einen Boden (15a) und eine Wandung (15b) umfasst, gebildet ist, und die Rohre (13) am Ende (13c) eine Öffnung oder Auskerbung (13d) aufweist.
  5. Vorrichtung nach Anspruch 4, dadurch gekennzeichnet, dass in der offenen Stellung- unter Einwirkung einer Feder (16), die zwischen dem Boden (15a) und einer Krempe (17a) eines hülsenförmigen Elements (17), das im Inneren des Endes (E2) angebracht ist- der Boden (15a) am Ende (13c) der Röhre (13) anliegt und der freie Rand der Wandung (15b) der Schale in Stosskontakt zur Dichtung (8) gerät, wobei das Element (17) eine axiale Öffnung (17c) für die Kommunikation des Inneren des Behälters (1) mit dem Inneren des vom Element (17) abgegrenzten Raums aufweist.
  6. Vorrichtung nach einem der Anspruche 1 bis 5, dadurch gekennzeichnet, dass der Behälter (1) und der Behälter (4) aus transparenten Materialien hergestellt sind.
  7. Vorrichtung nach einem der Anspruche 1 bis 5, dadurch gekennzeichnet, dass der Behälter (1) und der Behälter (4) mithilfe von Verbundmaterialien hergestellt sind, bei denen mindestens eine der Schichten, aus denen das Verbundmaterial aufgebaut ist, dem Verbundmaterial ausreichende mechanische Festigkeit verleiht, eine andere Schicht Gassperreigenschaften, insbesondere gegenüber Sauerstoff, Stickstoff und/oder Kohlendioxid, verleiht und eine wiederum andere Schicht Eigenschaften der chemischen Beständigkeit gegenüber dem abzugebenden Fluid verleiht.
  8. Vorrichtung nach Anspruch 7, dadurch gekennzeichnet, dass
    - die Schicht, die dazu geeignet ist, gute Eigenschaften der mechanischen Festigkeit zu verleihen, aus Polyethylenterephthalat oder PET gebildet ist,
    - die Schicht, die dazu geeignet ist, gute Gassperreigenschaften zu verleihen, aus Nylon, insbesondere Nylon MXD6, in Ethylenvinylalkoholharz (EVOH) oder in Siliciumoxid gebildet ist,
    - und die Schicht, die dazu geeignet ist, gute Eigenschaften der chemischen Beständigkeit zu verleihen, aus Polyethylenterephthalat gebildet ist.
  9. Vorrichtung nach Anspruch 7, dadurch gekennzeichnet, dass der Behälter (1) entweder aus einem PET/Nylon/PET-Verbundmaterial, d. h. umfassend eine äussere Schicht aus Polyethylenterephthalat, eine Zwischenschicht aus Nylon und eine innere Schicht, d.h. eine Schicht, die dazu vorgesehen ist, in Kontakt mit dem abzugebenden Fluid zu stehen, ebenfalls aus Polyethylenterephthalat, oder aus einem PET/EVOH/PET-Verbundmaterial hergestellt
    ist, wobei der Behälter (4) vorteilhafterweise aus dem gleichen Material oder einem zweischichtigen Verbundmaterial, insbesondere aus PETund Nylon, hergestellt ist.
  10. Vorrichtung nach einem der Ansprüche 1 bis 9, dadurch gekennzeichnet, dass die Falten oder Rippen (2) des Behälters (1) in zwei Schritten ausgebildet sind, wobei der erste darin besteht, Vorausbildungen der Rippen (21) am Behälter (1) auszubilden.
  11. Vorrichtung nach einem der Ansprüche 1 bis 9, dadurch gekennzeichnet, dass sie eine zylindrische Manschette (A) umfasst, die über dem Behälter (1) angeordnet ist, wobei die Manschette (A), die aus einem transparenten, elastischen, synthetischen Material gebildet ist, an ihrer Innenoberfläche Rippenansätze (25) tragt, die sich jeweils zwischen den einzelnen Rippen (2) des Behälters (1) anordnen.
EP06709317.9A 2005-02-15 2006-02-14 Vorrichtung zur ausgabe von fluiden, besonders arzneifluiden unter druck Active EP1851135B2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PL06709317T PL1851135T5 (pl) 2005-02-15 2006-02-14 Urządzenie do uwalniania płynów, w szczególności leczniczych, pod ciśnieniem

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0501511A FR2882037B1 (fr) 2005-02-15 2005-02-15 Dispositif apte a delivrer des fluides, notamment medicamenteux sous pression
FR0511571 2005-11-15
PCT/FR2006/000338 WO2006087462A1 (fr) 2005-02-15 2006-02-14 Dispositif apte a delivrer des fluides, notamment medicamenteux sous pression

Publications (4)

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EP1851135A1 EP1851135A1 (de) 2007-11-07
EP1851135B1 EP1851135B1 (de) 2008-07-16
EP1851135B8 EP1851135B8 (de) 2008-10-01
EP1851135B2 true EP1851135B2 (de) 2015-08-12

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EP06709317.9A Active EP1851135B2 (de) 2005-02-15 2006-02-14 Vorrichtung zur ausgabe von fluiden, besonders arzneifluiden unter druck

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US (1) US20080272145A1 (de)
EP (1) EP1851135B2 (de)
AT (1) ATE401259T1 (de)
CA (1) CA2597693C (de)
DE (1) DE602006001851D1 (de)
ES (1) ES2310909T5 (de)
PL (1) PL1851135T5 (de)
PT (1) PT1851135E (de)
WO (1) WO2006087462A1 (de)

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EP2681128B1 (de) 2011-03-02 2020-10-07 Greenspense Ltd. Unter druck stehender treibgasfreier materialspender und methode
US9296550B2 (en) 2013-10-23 2016-03-29 The Procter & Gamble Company Recyclable plastic aerosol dispenser
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Also Published As

Publication number Publication date
PT1851135E (pt) 2008-10-28
PL1851135T3 (pl) 2009-02-27
DE602006001851D1 (de) 2008-08-28
PL1851135T5 (pl) 2015-12-31
EP1851135A1 (de) 2007-11-07
CA2597693C (fr) 2014-10-07
US20080272145A1 (en) 2008-11-06
CA2597693A1 (fr) 2006-08-24
WO2006087462A1 (fr) 2006-08-24
ES2310909T5 (es) 2015-11-26
EP1851135B8 (de) 2008-10-01
EP1851135B1 (de) 2008-07-16
ATE401259T1 (de) 2008-08-15
ES2310909T3 (es) 2009-01-16

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