EP1814994A4 - Vorrichtung und system mit trockenen kontrollgen-verstummungszusammensetzungen - Google Patents

Vorrichtung und system mit trockenen kontrollgen-verstummungszusammensetzungen

Info

Publication number
EP1814994A4
EP1814994A4 EP05857003A EP05857003A EP1814994A4 EP 1814994 A4 EP1814994 A4 EP 1814994A4 EP 05857003 A EP05857003 A EP 05857003A EP 05857003 A EP05857003 A EP 05857003A EP 1814994 A4 EP1814994 A4 EP 1814994A4
Authority
EP
European Patent Office
Prior art keywords
gene silencing
sirna
well
reverse transfection
dry gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP05857003A
Other languages
English (en)
French (fr)
Other versions
EP1814994A2 (de
Inventor
Barbara Robertson
Devin Leake
Kathryn Robinson
William S Marshall
Anastasia Khvorova
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dharmacon Inc
Original Assignee
Dharmacon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/283,483 external-priority patent/US20060166234A1/en
Priority claimed from US11/283,484 external-priority patent/US7935811B2/en
Priority claimed from US11/283,482 external-priority patent/US7923207B2/en
Application filed by Dharmacon Inc filed Critical Dharmacon Inc
Publication of EP1814994A2 publication Critical patent/EP1814994A2/de
Publication of EP1814994A4 publication Critical patent/EP1814994A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/26—Inoculator or sampler
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/16—Apparatus for enzymology or microbiology containing, or adapted to contain, solid media
    • C12M1/18—Multiple fields or compartments
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Sustainable Development (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Saccharide Compounds (AREA)
EP05857003A 2004-11-22 2005-11-21 Vorrichtung und system mit trockenen kontrollgen-verstummungszusammensetzungen Withdrawn EP1814994A4 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US63032004P 2004-11-22 2004-11-22
US67816505P 2005-05-04 2005-05-04
US11/283,483 US20060166234A1 (en) 2004-11-22 2005-11-18 Apparatus and system having dry control gene silencing compositions
US11/283,484 US7935811B2 (en) 2004-11-22 2005-11-18 Apparatus and system having dry gene silencing compositions
US11/283,482 US7923207B2 (en) 2004-11-22 2005-11-18 Apparatus and system having dry gene silencing pools
US11/283,481 US7923206B2 (en) 2004-11-22 2005-11-18 Method of determining a cellular response to a biological agent
PCT/US2005/042404 WO2006071410A2 (en) 2004-11-22 2005-11-21 Apparatus and system having dry gene silencing compositions

Publications (2)

Publication Number Publication Date
EP1814994A2 EP1814994A2 (de) 2007-08-08
EP1814994A4 true EP1814994A4 (de) 2010-07-14

Family

ID=39758480

Family Applications (3)

Application Number Title Priority Date Filing Date
EP05849672A Withdrawn EP1815022A4 (de) 2004-11-22 2005-11-21 Verfahren zur bestimmung der zellreaktion auf einen biologischen wirkstoff
EP05852038A Not-in-force EP1814895B1 (de) 2004-11-22 2005-11-21 Vorrichtung und system mit trockener kontrollgen-verstummungszusammensetzung
EP05857003A Withdrawn EP1814994A4 (de) 2004-11-22 2005-11-21 Vorrichtung und system mit trockenen kontrollgen-verstummungszusammensetzungen

Family Applications Before (2)

Application Number Title Priority Date Filing Date
EP05849672A Withdrawn EP1815022A4 (de) 2004-11-22 2005-11-21 Verfahren zur bestimmung der zellreaktion auf einen biologischen wirkstoff
EP05852038A Not-in-force EP1814895B1 (de) 2004-11-22 2005-11-21 Vorrichtung und system mit trockener kontrollgen-verstummungszusammensetzung

Country Status (7)

Country Link
EP (3) EP1815022A4 (de)
JP (1) JP2008532480A (de)
KR (1) KR101277646B1 (de)
CN (1) CN101107352B (de)
AT (1) ATE519772T1 (de)
AU (1) AU2005322468B2 (de)
CA (1) CA2587786C (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060166234A1 (en) 2004-11-22 2006-07-27 Barbara Robertson Apparatus and system having dry control gene silencing compositions
US7923207B2 (en) 2004-11-22 2011-04-12 Dharmacon, Inc. Apparatus and system having dry gene silencing pools
US7935811B2 (en) 2004-11-22 2011-05-03 Dharmacon, Inc. Apparatus and system having dry gene silencing compositions
US10006024B2 (en) 2012-11-29 2018-06-26 Gifu University RNA interference agent, method for producing same, and use therefor
CN103966155B (zh) * 2013-04-25 2016-03-02 苏州吉诺瑞生物科技有限公司 一种利用自组装细胞芯片转染蛋白质或化合物的方法
JP2019012215A (ja) * 2017-06-30 2019-01-24 ブラザー工業株式会社 ラベル媒体及びカセット
US20210054406A1 (en) 2018-03-30 2021-02-25 Kyoto University Cell production method
US20230357767A1 (en) * 2020-08-25 2023-11-09 Bonac Corporation Novel nucleic acid molecule inhibiting expression of target gene

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040137064A1 (en) * 2003-01-15 2004-07-15 Lewis David L. Compositions and processes using siRNA, amphipathic compounds and polycations
WO2004090105A2 (en) * 2003-04-02 2004-10-21 Dharmacon, Inc. Modified polynucleotides for use in rna interference
WO2005097992A2 (en) * 2004-04-01 2005-10-20 Dharmacon, Inc. Modified polynucleotides for reducing off-target effects in rna interference

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6294350B1 (en) * 1997-06-05 2001-09-25 Dalhousie University Methods for treating fibroproliferative diseases
JP2003509060A (ja) * 1999-09-17 2003-03-11 ホワイトヘッド・インスティテュート・フォー・バイオメディカル・リサーチ 逆トランスフェクション方法
US20020006664A1 (en) * 1999-09-17 2002-01-17 Sabatini David M. Arrayed transfection method and uses related thereto
US20030170891A1 (en) * 2001-06-06 2003-09-11 Mcswiggen James A. RNA interference mediated inhibition of epidermal growth factor receptor gene expression using short interfering nucleic acid (siNA)
US20040019008A1 (en) * 2002-05-28 2004-01-29 Lewis David L. Compositions and processes using siRNA, amphipathic compounds and polycations
WO2004078946A2 (en) * 2003-03-05 2004-09-16 The Board Of Trustees Of The Leland Stanford Junior University Rnai arrays and methods for using the same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040137064A1 (en) * 2003-01-15 2004-07-15 Lewis David L. Compositions and processes using siRNA, amphipathic compounds and polycations
WO2004090105A2 (en) * 2003-04-02 2004-10-21 Dharmacon, Inc. Modified polynucleotides for use in rna interference
WO2005097992A2 (en) * 2004-04-01 2005-10-20 Dharmacon, Inc. Modified polynucleotides for reducing off-target effects in rna interference

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
AZA-BLANC P ET AL: "Identification of modulators of TRAIL-induced apoptosis via RNAi-based phenotypic screening", MOLECULAR CELL, CELL PRESS, CAMBRIDGE, MA, US, vol. 12, no. 3, 1 September 2003 (2003-09-01), pages 627 - 637, XP002350184, ISSN: 1097-2765, DOI: 10.1016/S1097-2765(03)00348-4 *
HONMA K. ET AL.: "The role of atelocollagen-based cell transfection array in high-throughput screening of gene functions and in drug discovery", CURRENT DRUG DISCOVERY TECHNOLOGIES, vol. 1, no. 4, 1 December 2004 (2004-12-01), pages 287 - 294, XP008092990, ISSN: 1570-1638 *
HONMA KIMI ET AL.: "Atelocollagen-based gene transfer in cells allows high-throughput screening of gene functions", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, vol. 289, no. 5, 21 December 2001 (2001-12-21), pages 1075 - 1081, XP002957375, ISSN: 0006-291X *
MINAKUCHI YOSHIKO ET AL.: "Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo", NUCLEIC ACIDS RESEARCH, vol. 32, no. 13, 22 July 2004 (2004-07-22), pages E109.1 - E109.7, XP002513223, ISSN: 1362-4962 *

Also Published As

Publication number Publication date
EP1814994A2 (de) 2007-08-08
EP1815022A4 (de) 2009-03-25
CN101107352B (zh) 2013-03-20
EP1814895A4 (de) 2008-05-28
AU2005322468A1 (en) 2006-07-06
AU2005322468B2 (en) 2011-03-10
CN101107352A (zh) 2008-01-16
JP2008532480A (ja) 2008-08-21
EP1815022A2 (de) 2007-08-08
CA2587786A1 (en) 2006-07-06
KR101277646B1 (ko) 2013-06-25
KR20070118585A (ko) 2007-12-17
EP1814895B1 (de) 2011-08-10
AU2005322468A2 (en) 2006-07-06
CA2587786C (en) 2017-12-05
EP1814895A2 (de) 2007-08-08
ATE519772T1 (de) 2011-08-15

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RIN1 Information on inventor provided before grant (corrected)

Inventor name: KHVOROVA, ANASTASIA

Inventor name: MARSHALL, WILLIAM, S.

Inventor name: ROBINSON, KATHRYN

Inventor name: LEAKE, DEVIN

Inventor name: ROBERTSON, BARBARA

DAX Request for extension of the european patent (deleted)
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Effective date: 20100615

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