EP1684633A2 - Placental blood sampling device - Google Patents

Placental blood sampling device

Info

Publication number
EP1684633A2
EP1684633A2 EP04805785A EP04805785A EP1684633A2 EP 1684633 A2 EP1684633 A2 EP 1684633A2 EP 04805785 A EP04805785 A EP 04805785A EP 04805785 A EP04805785 A EP 04805785A EP 1684633 A2 EP1684633 A2 EP 1684633A2
Authority
EP
European Patent Office
Prior art keywords
blood
collecting tank
needle
suction
sampling
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04805785A
Other languages
German (de)
French (fr)
Inventor
Patrice Richard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Praxcell
Original Assignee
Praxcell
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Praxcell filed Critical Praxcell
Publication of EP1684633A2 publication Critical patent/EP1684633A2/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150992—Blood sampling from a fluid line external to a patient, such as a catheter line, combined with an infusion line; blood sampling from indwelling needle sets, e.g. sealable ports, luer couplings, valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150038—Source of blood for blood from umbilical cord
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150015—Source of blood
    • A61B5/150045—Source of blood for blood from vagina, placenta, colon or mouth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150053—Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150061—Means for enhancing collection
    • A61B5/150099—Means for enhancing collection by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150229—Pumps for assisting the blood sampling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150305—Packages specially adapted for piercing devices or blood sampling devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150389—Hollow piercing elements, e.g. canulas, needles, for piercing the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
    • A61B5/150381—Design of piercing elements
    • A61B5/150503—Single-ended needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/15—Devices for taking samples of blood
    • A61B5/150007—Details
    • A61B5/150755—Blood sample preparation for further analysis, e.g. by separating blood components or by mixing

Definitions

  • the present invention relates to a device for collecting placental blood.
  • placental blood also called cord blood
  • cord blood which has particularly advantageous properties. This is usually done after the baby has been separated from the umbilical cord.
  • the person responsible for the collection then uses a system comprising one or more collection needle (s) with which he pierces the vein of the cord to collect by gravity the blood which it contains.
  • This operation is relatively long, typically of the order of twenty minutes, which taking into account the blood coagulation process, consequently limits the quantities withdrawn and the quality of the blood withdrawn.
  • the object of the present invention is to provide a device for collecting placental blood which does not have the abovementioned drawbacks.
  • the present invention aims to provide a device for collecting placental blood which is more efficient and which makes it possible to optimize the quantity and the quality of the blood collected.
  • the present invention also aims to provide such a device which is simple, inexpensive and safe to manufacture and use, especially in terms of sterility conditions.
  • the present invention therefore relates to a device for collecting placental blood, comprising at least one sampling needle intended to pierce the vein of the umbilical cord and / or the placenta, as well as a collecting reservoir connected to said at least one needle by intermediate of at least one pipe, the device comprising suction means connected to said at least one needle and suitable for sucking placental blood to supply it to said collecting tank, said suction means comprising a vacuum jar, in particular of the Redon type, simultaneously forming a collecting tank.
  • said suction means further comprise a vacuum pump.
  • the device comprises at least one injection and / or sampling site between said at least one sampling needle and said collecting tank.
  • at least one injection and / or sampling site is provided on the pipe.
  • At least one injection and / or sampling site is provided on the collecting tank.
  • said at least one suction and / or sampling site is used to inject an anti-coagulant product and / or take a blood sample for analysis and / or take the blood contained in said collecting tank.
  • said device comprises means for adjusting the flow of blood and / or means for adjusting suction.
  • said means for adjusting blood flow and / or said means for adjusting suction include an adjustable wheel.
  • said collecting tank contains an anticoagulant product before receiving said placental blood.
  • said device is packaged in a sterile manner and assembled in a common package to be ready for use after opening of said package.
  • This device comprises in known manner at least one sampling needle 10, 11.
  • two needles are provided, which makes it possible to carry out a sampling at two different places and at two successive times.
  • security systems 15 are provided on each needle 10, 11 to avoid any risk of injury before and after the sample is taken.
  • This or these needles 10, 11 is (are) connected (s) to a collecting tank 20 intended to receive the blood drawn.
  • a pipe 40 advantageously connects said collecting tank 20 to said at least one needle 10, 11.
  • the device comprises suction means 30 for sucking placental blood inside the collecting tank 20.
  • suction means 30 for sucking placental blood inside the collecting tank 20.
  • These means Aspiration therefore promotes rapid transfer of the blood to be drawn to the collecting tank 20, which makes it possible to collect a greater quantity of blood, to accelerate the collection process, to improve the quality of the blood collected and to limit the risks of coagulation thereof before it reaches the reservoir coEector 20.
  • the embodiment shown in the figure shows the use of a vacuum jar of the Redon type which is particularly advantageous for the present invention.
  • the Redon jar is a vacuum tank used after surgical procedures to aspirate the last post-operative balances on the patient. The use of such a Redon jar in the present invention makes it possible to obtain a quality and rapid sample.
  • the suction means can also include additional suction means, for example a vacuum pump or a peristaltic pump or any other type of pump. Of course other means of suction would also be possible.
  • a sampling tank connected or disposed inside a vacuum tank could also be used and other systems could also be used.
  • the sampling device comprises at least one injection and / or sampling site 51, 52, 53 provided between said at least one needle 10, 11 and said collecting tank 20.
  • an injection site 51 for injecting an appropriate anti-coagulant product for example heparin or CPD
  • a second sampling site 53 to take all of the blood contained in the collecting tank 20 at the end of the sampling process.
  • injection and / or withdrawal sites 51, 52, 53 can be arranged on the pipe 40, as shown, but they could also advantageously be produced directly on the collecting tank 20.
  • an insulated bag containing an anticoagulant can be connected to the device, for example at said injection site.
  • This pocket can for example be isolated by an adjustable or breakable device, allowing or not the passage of its contents to the collecting tank, as necessary.
  • an agitator device 25 is provided in the reservoir 20, for example a magnetic or movement agitator. This makes it possible in particular to improve the mixture of the blood drawn with the anticoagulant. To ensure proper operation of the device, the suction must not be too high, which would risk causing a constriction or blockage of the pipe 40, or too weak to be effective.
  • the device therefore advantageously comprises suction adjustment means 70, which can be produced in the form of an element adapted to modify the section of the pipe 40.
  • an adjustable wheel could be used.
  • adjustment means provided directly on the suction means 30, or even on the collecting tank 20 would also be possible.
  • means for regulating the flow of blood 60 which are advantageously disposed directly downstream of the sampling needles 10, 11, and which can also be produced in any desired manner, for example by means of '' an adjustable wheel.
  • Filters can be provided at the various sampling and / or injection sites, as well as upstream of the reservoir 20. For example, the presence of such a filter can allow the reservoir to be placed at atmospheric pressure immediately upon sampling. completed without risk of contamination and under sterile conditions.
  • a particular advantage of the present invention relates to its safety in use, and in particular its sterile nature.
  • the device of the invention can be assembled, sterilized and then packaged in a sterile manner in a common package, so that the user, when he wishes to draw placental blood, has only to open the sterile packaging and pierce the umbilical cord to draw blood without having to make any other assemblies.
  • the sterility of the device is therefore guaranteed at all times.
  • the present invention therefore makes it possible to provide a placental blood collection device which simplifies the collection process, which makes it safer and more efficient by optimizing both the quantity of blood collected and the quality thereof.

Abstract

The invention concerns a placental blood sampling device comprising at least one sampling needle (10, 11) for perforating the vein of the umbilical cord and/or of the placenta vein, as well as a collecting reservoir (20) connected to said at least one needle (10, 11) via at least one conduit (40), the device including suction means (30) connected to said at least one needle (10, 11) and adapted to draw out placental blood to supply it to said collecting reservoir (20), said suction means (30) including a Redon type vacuum jar (20), forming simultaneously a collecting reservoir.

Description

Dispositif de prélèvement de sang placentaire Placental blood collection device
La présente invention concerne un dispositif de prélèvement de sang placentaire. Au cours d'un accouchement, il est connu de prélever le sang placentaire, également appelé sang de cordon, qui présente des propriétés particulièrement intéressantes. Ce prélèvement est généralement réalisé après que le bébé a été séparé du cordon ombilical. La personne responsable du prélèvement utilise alors un système comportant une ou plusieurs aiguille(s) de prélèvement avec laquelle elle perce la veine du cordon pour prélever par gravité le sang que celui- ci contient. Cette opération est relativement longue, typiquement de l'ordre d'une vingtaine de minutes, ce qui compte tenu du processus de coagulation du sang, limite par conséquent les quantités prélevées et la qualité du sang prélevé. La présente invention a pour but de fournir un dispositif de prélèvement de sang placentaire qui ne reproduit pas les inconvénients susmentionnés. Plus particulièrement, la présente invention a pour but de fournir un dispositif de prélèvement de sang placentaire qui soit plus efficace et qui permette d'optimiser la quantité et la qualité du sang prélevé. La présente invention a également pour but de fournir un tel dispositif qui soit simple, peu coûteux et sûr à fabriquer et à utiliser, notamment au niveau des conditions de stérilité. La présente invention a donc pour objet un dispositif de prélèvement de sang placentaire, comprenant au moins une aiguille de prélèvement destinée à percer la veine du cordon ombilical et/ou du placenta, ainsi qu'un réservoir collecteur relié à ladite au moins une aiguille par intermédiaire d'au moins un tuyau, le dispositif comportant des moyens d'aspiration connectés à ladite au moins une aiguille et adaptés à aspirer le sang placentaire pour l'alimenter audit réservoir collecteur, lesdits moyens d'aspiration comportant un bocal à vide, notamment du type Redon, formant simultanément réservoir collecteur. Avantageusement, lesdits moyens d'aspiration comportent en outre une pompe à vide. Avantageusement, le dispositif comporte au moins un site d'injection et/ou de prélèvement entre ladite au moins une aiguille de prélèvement et ledit réservoir collecteur. Avantageusement, au moins un site d'injection et/ou de prélèvement est prévu sur le tuyau. Avantageusement, au moins un site d'injection et/ou de prélèvement est prévu sur le réservoir collecteur. Avantageusement, ledit au moins un site d'aspiration et/ou de prélèvement est utilisé pour injecter un produit anti-coagulant et/ou prélever un échantillon de sang pour analyse et/ou prélever le sang contenu dans ledit réservoir collecteur. Avantageusement, ledit dispositif comporte des moyens de réglage d'écoulement du sang et/ou des moyens de réglage d'aspiration. Avantageusement, lesdits moyens de réglage d'écoulement de sang et/ou lesdits moyens de réglage d'aspiration comportent une molette réglable. Avantageusement, ledit réservoir collecteur contient un produit anticoagulant avant de recevoir ledit sang placentaire. Avantageusement, ledit dispositif est emballé de manière stérile et assemblée dans un emballage commun pour être prêt à l'emploi après ouverture dudit emballage. D'autres caractéristiques et avantages de la présente invention apparaîtront plus clairement au cours de la description détaillée suivante d'un mode de réalisation avantageux de celle-ci, faite en référence à la figure unique, donnée à titre d'exemple non limitatif, et qui montre schématiquement un dispositif de prélèvement de sang placentaire selon un mode de réalisation particulier de la présente invention. Ce dispositif comporte de manière connue au moins une aiguille de prélèvement 10, 11. De préférence, on prévoit deux aiguilles, ce qui permet de réaliser un prélèvement en deux endroits différents et à deux moments successifs. Avantageusement, des systèmes de sécurité 15 sont prévus sur chaque aiguille 10, 11 pour éviter tout risque de blessure avant et après le prélèvement. Cette ou ces aiguilles 10, 11 est (sont) reliée(s) à un réservoir collecteur 20 destiné à recevoir le sang prélevé. Un tuyau 40 relie avantageusement ledit réservoir collecteur 20 à ladite au moins une aiguille 10, 11. Selon l'invention, le dispositif comporte des moyens d'aspiration 30 pour aspirer le sang placentaire à l'intérieur du réservoir collecteur 20. Ces moyens d'aspiration favorisent donc un transfert rapide du sang à prélever vers le réservoir collecteur 20, ce qui permet de collecter une quantité de sang supérieure, d'accélérer le processus de prélèvement, d'améliorer la qualité du sang prélevé et de limiter les risques de coagulation de celui-ci avant qu'il n'arrive au réservoir coEecteur 20. Le mode de réalisation représenté sur la figure montre l'utilisation d'un bocal à vide du type Redon qui est particulièrement avantageuse pour la présente invention. Le bocal Redon est un réservoir à vide utilisé après des interventions chirurgicales pour aspirer les derniers reliquats hquides post opératoires sur le patient. L'utilisation d'un tel bocal Redon dans la présente invention permet d'obtenir un prélèvement de qualité et rapide. Les moyens d'aspiration peuvent aussi comporter des moyens d'aspiration supplémentaires, par exemple une pompe à vide ou une pompe péristaltique ou tout autre type de pompe. Bien entendu d'autres moyens d'aspirations seraient également envisageables. Par exemple une cuve de prélèvement connectée ou disposée à l'intérieur d'un réservoir à vide pourrait également être utilisée et d'autres systèmes seraient aussi utilisables. Selon un aspect avantageux de la présente invention, le dispositif de prélèvement comporte au moins un site d'injection et/ou de prélèvement 51, 52, 53 prévu entre ladite au moins une aiguille 10, 11 et ledit réservoir collecteur 20. Sur l'exemple représenté, il y a trois sites de ce type, à savoir un site d'injection 51 pour injecteur un produit anti-coagulant approprié, par exemple de l'héparine ou du CPD, pendant le processus de prélèvement, un premier site de prélèvement 52 pour prélever un échantillon du sang en cours de prélèvement pour l'analyser, par exemple pour faire des tests d'hépatite ou HTV, et un deuxième site de prélèvement 53 pour prélever la totalité du sang contenu dans le réservoir collecteur 20 à la fin du processus de prélèvement. Ces sites d'injection et/ou de prélèvement 51, 52, 53 peuvent être disposés sur le tuyau 40, comme représenté, mais ils pourraient également avantageusement être réalisés directement sur le réservoir collecteur 20. De même, de manière avantageuse, on peut prévoir de disposer dans le réservoir collecteur 20 une quantité appropriée de produit anti-coagulant, par exemple d'héparine, avant le début du processus de prélèvement. En variante, on peut prévoir une poche isolée contenant un anticoagulant et reliée au dispositif, par exemple au niveau dudit site d'injection. Cette poche peut par exemple être isolée par un dispositif réglable ou sécable, permettant ou non le passage de son contenu vers le réservoir collecteur, selon la nécessité. Avantageusement, on prévoit un dispositif agitateur 25 dans le réservoir 20, par exemple un agitateur magnétique ou à mouvement. Ceci permet notamment d'améliorer le mélange du sang prélevé avec l'anti-coagulant. Pour assurer un bon fonctionnement du dispositif, l'aspiration ne doit pas être trop importante, ce qui risquerait de provoquer une constriction ou bouchage du tuyau 40, ni trop faible pour être efficace. Le dispositif comporte donc avantageusement des moyens de réglage d'aspiration 70, qui peuvent être réalisés sous la forme d'un élément adapté à modifier la section du tuyau 40. Avantageusement, une molette réglable pourrait être utilisée. En variante, des moyens de réglage prévus directement sur les moyens d'aspiration 30, voire sur le réservoir collecteur 20 seraient également envisageables. De même, il est avantageusement prévu des moyens de réglage d'écoulement du sang 60 qui sont avantageusement disposés directement en aval des aiguilles de prélèvement 10, 11, et qui peuvent également être réalisés d'une manière quelconque souhaitée, par exemple au moyen d'une molette réglable. Des filtres peuvent être prévus au niveau des différents sites de prélèvement et/ou d'injection, ainsi qu'en amont du réservoir 20. Par exemple, la présence d'un tel filtre peut permettre la mise du réservoir à pression atmosphérique aussitôt le prélèvement terminé sans risque de contamination et dans des conditions stériles. Un avantage particulier de la présente invention concerne sa sécurité d'utilisation, et notamment son caractère stérile. En effet, le dispositif de l'invention peut être assemblé, stérilisé puis emballé de manière stérile dans un emballage commun, de sorte que l'utilisateur, lorsqu'il souhaite prélever du sang placentaire, n'a plus qu'à ouvrir l'emballage stérile et à percer le cordon ombilical pour prélever le sang sans avoir d'autres assemblages à faire. La stérilité du dispositif est donc garantie à tout moment. La présente invention permet donc de fournir un dispositif de prélèvement de sang placentaire qui simplifie le processus de prélèvement, qui le rend plus sûr, et plus efficace en optimisant à la fois la quantité de sang prélevé et la qualité de celui-ci. Bien que la présente invention ait été décrite en référence à un mode de réalisation particulier de celle-ci, il est entendu qu'elle n'est pas limitée par l'exemple représenté. Au contraire, un homme du métier peut y apporter toutes modifications utiles sans sortir du cadre de la présente invention tel que défini par les revendications annexées. The present invention relates to a device for collecting placental blood. During childbirth, it is known to draw placental blood, also called cord blood, which has particularly advantageous properties. This is usually done after the baby has been separated from the umbilical cord. The person responsible for the collection then uses a system comprising one or more collection needle (s) with which he pierces the vein of the cord to collect by gravity the blood which it contains. This operation is relatively long, typically of the order of twenty minutes, which taking into account the blood coagulation process, consequently limits the quantities withdrawn and the quality of the blood withdrawn. The object of the present invention is to provide a device for collecting placental blood which does not have the abovementioned drawbacks. More particularly, the present invention aims to provide a device for collecting placental blood which is more efficient and which makes it possible to optimize the quantity and the quality of the blood collected. The present invention also aims to provide such a device which is simple, inexpensive and safe to manufacture and use, especially in terms of sterility conditions. The present invention therefore relates to a device for collecting placental blood, comprising at least one sampling needle intended to pierce the vein of the umbilical cord and / or the placenta, as well as a collecting reservoir connected to said at least one needle by intermediate of at least one pipe, the device comprising suction means connected to said at least one needle and suitable for sucking placental blood to supply it to said collecting tank, said suction means comprising a vacuum jar, in particular of the Redon type, simultaneously forming a collecting tank. Advantageously, said suction means further comprise a vacuum pump. Advantageously, the device comprises at least one injection and / or sampling site between said at least one sampling needle and said collecting tank. Advantageously, at least one injection and / or sampling site is provided on the pipe. Advantageously, at least one injection and / or sampling site is provided on the collecting tank. Advantageously, said at least one suction and / or sampling site is used to inject an anti-coagulant product and / or take a blood sample for analysis and / or take the blood contained in said collecting tank. Advantageously, said device comprises means for adjusting the flow of blood and / or means for adjusting suction. Advantageously, said means for adjusting blood flow and / or said means for adjusting suction include an adjustable wheel. Advantageously, said collecting tank contains an anticoagulant product before receiving said placental blood. Advantageously, said device is packaged in a sterile manner and assembled in a common package to be ready for use after opening of said package. Other characteristics and advantages of the present invention will appear more clearly during the following detailed description of an advantageous embodiment thereof, given with reference to the single figure, given by way of nonlimiting example, and which schematically shows a placental blood collection device according to a particular embodiment of the present invention. This device comprises in known manner at least one sampling needle 10, 11. Preferably, two needles are provided, which makes it possible to carry out a sampling at two different places and at two successive times. Advantageously, security systems 15 are provided on each needle 10, 11 to avoid any risk of injury before and after the sample is taken. This or these needles 10, 11 is (are) connected (s) to a collecting tank 20 intended to receive the blood drawn. A pipe 40 advantageously connects said collecting tank 20 to said at least one needle 10, 11. According to the invention, the device comprises suction means 30 for sucking placental blood inside the collecting tank 20. These means Aspiration therefore promotes rapid transfer of the blood to be drawn to the collecting tank 20, which makes it possible to collect a greater quantity of blood, to accelerate the collection process, to improve the quality of the blood collected and to limit the risks of coagulation thereof before it reaches the reservoir coEector 20. The embodiment shown in the figure shows the use of a vacuum jar of the Redon type which is particularly advantageous for the present invention. The Redon jar is a vacuum tank used after surgical procedures to aspirate the last post-operative balances on the patient. The use of such a Redon jar in the present invention makes it possible to obtain a quality and rapid sample. The suction means can also include additional suction means, for example a vacuum pump or a peristaltic pump or any other type of pump. Of course other means of suction would also be possible. For example, a sampling tank connected or disposed inside a vacuum tank could also be used and other systems could also be used. According to an advantageous aspect of the present invention, the sampling device comprises at least one injection and / or sampling site 51, 52, 53 provided between said at least one needle 10, 11 and said collecting tank 20. On the example shown, there are three sites of this type, namely an injection site 51 for injecting an appropriate anti-coagulant product, for example heparin or CPD, during the sampling process, a first sampling site 52 to take a sample of the blood being drawn for analysis, for example to do hepatitis or HTV tests, and a second sampling site 53 to take all of the blood contained in the collecting tank 20 at the end of the sampling process. These injection and / or withdrawal sites 51, 52, 53 can be arranged on the pipe 40, as shown, but they could also advantageously be produced directly on the collecting tank 20. Similarly, advantageously, provision can be made to have in the collecting tank 20 an appropriate quantity of anticoagulant product, for example heparin, before the start of the sampling process. Alternatively, one can provide an insulated bag containing an anticoagulant and connected to the device, for example at said injection site. This pocket can for example be isolated by an adjustable or breakable device, allowing or not the passage of its contents to the collecting tank, as necessary. Advantageously, an agitator device 25 is provided in the reservoir 20, for example a magnetic or movement agitator. This makes it possible in particular to improve the mixture of the blood drawn with the anticoagulant. To ensure proper operation of the device, the suction must not be too high, which would risk causing a constriction or blockage of the pipe 40, or too weak to be effective. The device therefore advantageously comprises suction adjustment means 70, which can be produced in the form of an element adapted to modify the section of the pipe 40. Advantageously, an adjustable wheel could be used. Alternatively, adjustment means provided directly on the suction means 30, or even on the collecting tank 20 would also be possible. Likewise, there are advantageously provided means for regulating the flow of blood 60 which are advantageously disposed directly downstream of the sampling needles 10, 11, and which can also be produced in any desired manner, for example by means of '' an adjustable wheel. Filters can be provided at the various sampling and / or injection sites, as well as upstream of the reservoir 20. For example, the presence of such a filter can allow the reservoir to be placed at atmospheric pressure immediately upon sampling. completed without risk of contamination and under sterile conditions. A particular advantage of the present invention relates to its safety in use, and in particular its sterile nature. Indeed, the device of the invention can be assembled, sterilized and then packaged in a sterile manner in a common package, so that the user, when he wishes to draw placental blood, has only to open the sterile packaging and pierce the umbilical cord to draw blood without having to make any other assemblies. The sterility of the device is therefore guaranteed at all times. The present invention therefore makes it possible to provide a placental blood collection device which simplifies the collection process, which makes it safer and more efficient by optimizing both the quantity of blood collected and the quality thereof. Although the present invention has been described with reference to a particular embodiment thereof, it is understood that it is not limited by the example shown. On the contrary, a person skilled in the art can make any useful modifications to it without departing from the scope of the present invention as defined by the appended claims.

Claims

Revendications claims
1.- Dispositif de prélèvement de sang placentaire, comprenant au moins une aiguille de prélèvement (10, 11) destinée à percer la veine du cordon ombilical et/ou du placenta, ainsi qu'un réservoir collecteur (20) relié à ladite au moins une aiguille (10, 11) par l'intermédiaire d'au moins un tuyau (40), caractérisé en ce que le dispositif comporte des moyens d'aspiration (30) connectés à ladite au moins une aiguille (10, 11) et adaptés à aspirer le sang placentaire pour l'alimenter audit réservoir collecteur (20, lesdits moyens d'aspiration (30) comportant un bocal à vide (20), notamment du type Redon, formant simultanément réservoir collecteur. 1.- Device for collecting placental blood, comprising at least one sampling needle (10, 11) intended to pierce the vein of the umbilical cord and / or the placenta, as well as a collecting reservoir (20) connected to said at least a needle (10, 11) by means of at least one pipe (40), characterized in that the device comprises suction means (30) connected to said at least one needle (10, 11) and adapted sucking the placental blood to supply it to said collecting tank (20, said suction means (30) comprising a vacuum jar (20), in particular of the Redon type, simultaneously forming collecting tank.
2.- Dispositif selon la revendication 1, dans lequel lesdits moyens d'aspiration (30) comportent une pompe à vide. 2.- Device according to claim 1, wherein said suction means (30) comprise a vacuum pump.
3.- Dispositif selon l'une quelconque des revendications précédentes, dans lequel le dispositif comporte au moins un site d'injection et/ou de prélèvement (51, 52, 53) entre ladite au moins une aiguille de prélèvement (11, 12) et ledit réservoir collecteur (20). 3.- Device according to any one of the preceding claims, wherein the device comprises at least one injection and / or sampling site (51, 52, 53) between said at least one sampling needle (11, 12) and said collecting tank (20).
4.- Dispositif selon la revendication 3, dans lequel au moins un site d'injection et/ou de prélèvement (51, 52, 53) est prévu sur le tuyau (40). 4.- Device according to claim 3, wherein at least one injection and / or sampling site (51, 52, 53) is provided on the pipe (40).
5.- Dispositif selon la revendication 3 ou 4, dans lequel au moins un site d'injection et/ou de prélèvement (51, 52, 53) est prévu sur le réservoir collecteur (20). 5.- Device according to claim 3 or 4, wherein at least one injection and / or sampling site (51, 52, 53) is provided on the collecting tank (20).
6.- Dispositif selon l'une quelconque des revendications 3 à 5, dans lequel ledit au moins un site d'aspiration et/ou de prélèvement (51, 52, 53) est utilisé pour injecter un produit anti-coagulant et/ou prélever un échantillon de sang pour analyse et/ou prélever le sang contenu dans ledit réservoir collecteur (20). 6.- Device according to any one of claims 3 to 5, wherein said at least one suction and / or sampling site (51, 52, 53) is used to inject an anti-coagulant product and / or withdraw a blood sample for analysis and / or taking the blood contained in said collecting tank (20).
7.- Dispositif selon l'une quelconque des revendications précédentes, dans lequel ledit dispositif comporte des moyens de réglage d'écoulement du sang (60) et/ou des moyens de réglage d'aspiration (70). 7.- Device according to any one of the preceding claims, wherein said device comprises means for adjusting the flow of blood (60) and / or means for adjusting suction (70).
8.- Dispositif selon la revendication 7, dans lequel lesdits moyens de réglage d'écoulement de sang (60) et/ou lesdits moyens de réglage d'aspiration (70) comportent une molette réglable. 8.- Device according to claim 7, wherein said blood flow adjustment means (60) and / or said suction adjustment means (70) comprise an adjustable wheel.
9.- Dispositif selon l'une quelconque des revendications précédentes, dans lequel ledit réservoir collecteur (20) contient un produit anti-coagulant avant de recevoir ledit sang placentaire. 9.- Device according to any one of the preceding claims, wherein said collecting tank (20) contains an anti-coagulant product before receiving said placental blood.
10.- Dispositif selon Tune quelconque des revendications précédentes, dans lequel ledit dispositif est emballé de manière stérile et assemblée dans un emballage commun pour être prêt à l'emploi après ouverture dudit emballage. 10.- Device according to any one of the preceding claims, wherein said device is packaged in a sterile manner and assembled in a common package to be ready for use after opening of said package.
EP04805785A 2003-10-27 2004-10-27 Placental blood sampling device Withdrawn EP1684633A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0312543A FR2861282B1 (en) 2003-10-27 2003-10-27 PLACENTAL BLOOD SAMPLING DEVICE.
PCT/FR2004/050542 WO2005041772A2 (en) 2003-10-27 2004-10-27 Placental blood sampling device

Publications (1)

Publication Number Publication Date
EP1684633A2 true EP1684633A2 (en) 2006-08-02

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EP04805785A Withdrawn EP1684633A2 (en) 2003-10-27 2004-10-27 Placental blood sampling device

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US (1) US20070112280A1 (en)
EP (1) EP1684633A2 (en)
JP (1) JP2007509675A (en)
CN (1) CN1886092A (en)
AU (1) AU2004285322A1 (en)
BR (1) BRPI0415889A (en)
CA (1) CA2543702A1 (en)
FR (1) FR2861282B1 (en)
RU (1) RU2006118336A (en)
WO (1) WO2005041772A2 (en)

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US20070112280A1 (en) 2007-05-17
RU2006118336A (en) 2007-12-10
AU2004285322A1 (en) 2005-05-12
BRPI0415889A (en) 2007-01-09
CA2543702A1 (en) 2005-05-12
FR2861282B1 (en) 2007-07-06
CN1886092A (en) 2006-12-27
WO2005041772A2 (en) 2005-05-12
WO2005041772A3 (en) 2005-07-07
JP2007509675A (en) 2007-04-19
FR2861282A1 (en) 2005-04-29

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