EP1684078A3 - Chemisches Analysegerät und Analysevorrichtung - Google Patents

Chemisches Analysegerät und Analysevorrichtung Download PDF

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Publication number
EP1684078A3
EP1684078A3 EP20050028659 EP05028659A EP1684078A3 EP 1684078 A3 EP1684078 A3 EP 1684078A3 EP 20050028659 EP20050028659 EP 20050028659 EP 05028659 A EP05028659 A EP 05028659A EP 1684078 A3 EP1684078 A3 EP 1684078A3
Authority
EP
European Patent Office
Prior art keywords
electrodes
analysis device
reagent
sample
oil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP20050028659
Other languages
English (en)
French (fr)
Other versions
EP1684078A2 (de
Inventor
Hideo c/o Hitachi Ltd. Int. Prop. Grou Enoki
Hironobu c/o Hitachi Ltd. Int. Prop. Yamakawa
Kunio c/o Hitachi Ltd. Int. Prop. Group Harada
Sakuichiro c/o Hitachi Ltd. Int. Prop. Adachi
Tomonori c/o Hitachi Ltd. Int. Prop. Gr Mimura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hitachi High Tech Corp
Original Assignee
Hitachi High Technologies Corp
Hitachi High Tech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hitachi High Technologies Corp, Hitachi High Tech Corp filed Critical Hitachi High Technologies Corp
Publication of EP1684078A2 publication Critical patent/EP1684078A2/de
Publication of EP1684078A3 publication Critical patent/EP1684078A3/de
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502769—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements
    • B01L3/502784—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics
    • B01L3/502792—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by multiphase flow arrangements specially adapted for droplet or plug flow, e.g. digital microfluidics for moving individual droplets on a plate, e.g. by locally altering surface tension
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1016—Control of the volume dispensed or introduced
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/089—Virtual walls for guiding liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/02—Drop detachment mechanisms of single droplets from nozzles or pins
    • B01L2400/027—Drop detachment mechanisms of single droplets from nozzles or pins electrostatic forces between substrate and tip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0427—Electrowetting
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099—Characterised by type of test elements
    • G01N2035/00158—Elements containing microarrays, i.e. "biochip"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178—Special arrangements of analysers
    • G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
EP20050028659 2005-01-21 2005-12-29 Chemisches Analysegerät und Analysevorrichtung Withdrawn EP1684078A3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2005014493A JP4427461B2 (ja) 2005-01-21 2005-01-21 化学分析装置及び分析デバイス

Publications (2)

Publication Number Publication Date
EP1684078A2 EP1684078A2 (de) 2006-07-26
EP1684078A3 true EP1684078A3 (de) 2011-06-15

Family

ID=36177737

Family Applications (1)

Application Number Title Priority Date Filing Date
EP20050028659 Withdrawn EP1684078A3 (de) 2005-01-21 2005-12-29 Chemisches Analysegerät und Analysevorrichtung

Country Status (4)

Country Link
US (1) US20060166373A1 (de)
EP (1) EP1684078A3 (de)
JP (1) JP4427461B2 (de)
CN (2) CN100491995C (de)

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EP1947463A1 (de) * 2007-01-16 2008-07-23 Roche Diagnostics GmbH Entnahme von flüssigen Analyseproben zum Zweck der klinischen Analyse
JP4966913B2 (ja) * 2007-05-15 2012-07-04 株式会社日立ハイテクノロジーズ 液体分注装置
US8562807B2 (en) * 2007-12-10 2013-10-22 Advanced Liquid Logic Inc. Droplet actuator configurations and methods
US9103782B2 (en) 2008-12-02 2015-08-11 Malvern Instruments Incorporated Automatic isothermal titration microcalorimeter apparatus and method of use
CH700127A1 (de) * 2008-12-17 2010-06-30 Tecan Trading Ag System und Vorrichtung zur Aufarbeitung biologischer Proben und zur Manipulation von Flüssigkeiten mit biologischen Proben.
US8673627B2 (en) * 2009-05-29 2014-03-18 Life Technologies Corporation Apparatus and methods for performing electrochemical reactions
CN101692093B (zh) * 2009-09-28 2012-07-04 北京吉天仪器有限公司 水中阴离子表面活性剂的自动分析仪和自动分析方法
EP2611541A4 (de) * 2010-08-31 2016-11-02 Canon Us Life Sciences Inc Verfahren, vorrichtungen und systeme zur mischung von fluiden und chip-schnittstelle dafür
US9114399B2 (en) 2010-08-31 2015-08-25 Canon U.S. Life Sciences, Inc. System and method for serial processing of multiple nucleic acid assays
US8173000B1 (en) * 2011-01-18 2012-05-08 Sharp Kabushiki Kaisha Active matrix device and method of driving the same
US9588132B2 (en) 2011-04-08 2017-03-07 Artel, Inc. Validation method for automated analyzers
JP5835924B2 (ja) * 2011-04-08 2015-12-24 晃 服部 自動分析装置の検定方法
CN102253230B (zh) * 2011-07-01 2015-04-22 江苏英诺华医疗技术有限公司 一种血小板自动化分析仪及其分析方法
US9606104B2 (en) 2011-07-13 2017-03-28 Sinnowa Medical Science & Technology Co., Ltd. Automated platelet function analyzer and its analytical methods
JP5736280B2 (ja) * 2011-09-06 2015-06-17 株式会社日立ハイテクノロジーズ 自動分析装置
JP5919710B2 (ja) * 2011-10-03 2016-05-18 セイコーエプソン株式会社 熱サイクル装置
WO2014167858A1 (ja) * 2013-04-12 2014-10-16 パナソニック株式会社 溶媒制御方法およびエレクトロウェッティング用溶媒
MX2016001965A (es) * 2013-08-22 2016-06-02 Becton Dickinson Co Metodo y aparato nefelometrico para determinar la concentracion de particulas suspendidas en una serie de recipientes de muestra.
US10486156B2 (en) 2014-05-09 2019-11-26 Dh Technologies Development Pte. Ltd. Fluid transfer from digital microfluidic device
JP6506077B2 (ja) * 2015-03-31 2019-04-24 シスメックス株式会社 尿検体分析装置、尿検体分注方法及び尿検体処理方法
GB2542372A (en) * 2015-09-16 2017-03-22 Sharp Kk Microfluidic device and a method of loading fluid therein
CN108291871A (zh) * 2015-11-13 2018-07-17 惠普发展公司，有限责任合伙企业 物质检测
CN106814120B (zh) * 2017-01-23 2019-01-25 天津质谱生物科技有限公司 一种用于水质检测的实用型溶氧分析设备
CN107389391B (zh) * 2017-05-11 2024-02-27 武汉康录生物技术股份有限公司 一种自动脱蜡抗原修复系统
US20190064173A1 (en) 2017-08-22 2019-02-28 10X Genomics, Inc. Methods of producing droplets including a particle and an analyte
WO2019083852A1 (en) * 2017-10-26 2019-05-02 10X Genomics, Inc. MICROFLUIDIC CHANNEL NETWORKS FOR PARTITIONING
JP7053880B2 (ja) * 2018-10-31 2022-04-12 株式会社日立ハイテク 電解質分析装置
CN111215159A (zh) * 2018-11-26 2020-06-02 南京怡天生物科技有限公司 微流控芯片及基于该芯片融合样本的方法

Citations (5)

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Publication number Priority date Publication date Assignee Title
US5486337A (en) * 1994-02-18 1996-01-23 General Atomics Device for electrostatic manipulation of droplets
WO1999015876A1 (en) * 1997-09-19 1999-04-01 Aclara Biosciences, Inc. Apparatus and method for transferring liquids
WO1999054730A1 (en) * 1998-04-20 1999-10-28 Wallac Oy Method and device for carrying out a chemical analysis in small amounts of liquid
US20040055891A1 (en) * 2002-09-24 2004-03-25 Pamula Vamsee K. Methods and apparatus for manipulating droplets by electrowetting-based techniques
WO2005005961A1 (ja) * 2003-07-09 2005-01-20 Olympus Corporation 液体搬送処理デバイス及び液体搬送処理方法

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JP3791999B2 (ja) * 1997-03-24 2006-06-28 株式会社アドバンス 液体微粒子ハンドリング装置
JP3558898B2 (ja) * 1998-11-05 2004-08-25 株式会社日立製作所 自動分析装置及び自動分析方法
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Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5486337A (en) * 1994-02-18 1996-01-23 General Atomics Device for electrostatic manipulation of droplets
WO1999015876A1 (en) * 1997-09-19 1999-04-01 Aclara Biosciences, Inc. Apparatus and method for transferring liquids
WO1999054730A1 (en) * 1998-04-20 1999-10-28 Wallac Oy Method and device for carrying out a chemical analysis in small amounts of liquid
US20040055891A1 (en) * 2002-09-24 2004-03-25 Pamula Vamsee K. Methods and apparatus for manipulating droplets by electrowetting-based techniques
WO2005005961A1 (ja) * 2003-07-09 2005-01-20 Olympus Corporation 液体搬送処理デバイス及び液体搬送処理方法

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Title
M.G. POLLACK ET AL.: "Electrowetting-based actuation of droplets for integrated microfluidics", LAB CHIP, vol. 2, 11 March 2002 (2002-03-11), pages 96 - 101, XP002620011 *
T. TANIGUCHI ET AL.: "Chemical reactions in microdroplets by electrostatic manipulation of droplets in liquid media", LAB CHIP, vol. 2, 22 January 2002 (2002-01-22), pages 19 - 23, XP002620012 *

Also Published As

Publication number Publication date
CN101334420B (zh) 2012-05-16
EP1684078A2 (de) 2006-07-26
CN101334420A (zh) 2008-12-31
JP4427461B2 (ja) 2010-03-10
JP2006201083A (ja) 2006-08-03
US20060166373A1 (en) 2006-07-27
CN100491995C (zh) 2009-05-27
CN1808110A (zh) 2006-07-26

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