EP1680074A1 - Blanchiment dentaire - Google Patents

Blanchiment dentaire

Info

Publication number
EP1680074A1
EP1680074A1 EP04780790A EP04780790A EP1680074A1 EP 1680074 A1 EP1680074 A1 EP 1680074A1 EP 04780790 A EP04780790 A EP 04780790A EP 04780790 A EP04780790 A EP 04780790A EP 1680074 A1 EP1680074 A1 EP 1680074A1
Authority
EP
European Patent Office
Prior art keywords
composition
teeth
whitening
bleaching
petrolatum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04780790A
Other languages
German (de)
English (en)
Inventor
Jianxun Feng
Robert L. Ibsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Personal Products Co
Original Assignee
Personal Products Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/914,835 external-priority patent/US20050036958A1/en
Application filed by Personal Products Co filed Critical Personal Products Co
Publication of EP1680074A1 publication Critical patent/EP1680074A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/22—Peroxides; Oxygen; Ozone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/817—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)
    • A61K8/8176—Homopolymers of N-vinyl-pyrrolidones. Compositions of derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

Definitions

  • TECHNICAL FIELD This invention relates dental bleaching compositions, and to methods of using the same.
  • BACKGROUND Teeth enamel discoloration can be caused by staining, aging, or chemical damage to teeth. Some of the more common causes of teeth discoloration are medications, coffee, tea or cigarettes. People who drink significant amounts of cola soft drinks can experience similar staining. Aside from staining, there are other factors that can affect the color of an individual's teeth. Genetics can play a role.
  • Whitening teeth through bleaching solutions is yet one means to address stains or discoloration of the teeth.
  • These products contain peroxide(s), which actually bleach the tooth enamel.
  • These products typically rely on carbamide peroxide as the bleaching agent and are available in several different concentrations (10%, 16%, 22%).
  • Peroxide-containing whiteners typically come in a gel and are placed in a mouthguard. Usage regimens vary. Some products are used for about twice a day for 2 weeks, and others are intended for overnight use for 1-2 weeks.
  • dental whitening or bleaching typically involves either application of a whitening gel by a dental professional in his/her office (a "chairside application"), application of a whitening gel using a tray or mouthguard that is either custom-made, preformed, or formed by the user prior to application of the gel (e.g., a "boil and bite” tray), or brushing with a dentifrice that provides a whitening agent sometimes with other hygienically-beneficial agents.
  • a dental professional in his/her office a "chairside application”
  • a whitening gel e.g., a "boil and bite” tray
  • brushing with a dentifrice that provides a whitening agent sometimes with other hygienically-beneficial agents.
  • bleaching agents have included peroxides, percarbonates and perborates of the alkali and alkaline earth metals or complex compounds containing hydrogen peroxide.
  • peroxide salts of the alkali or alkaline earth metals are known to be useful in whitening teeth. Thickened mixtures containing hydrogen peroxide for use as a whitening agent have been described in U.S. Patent Nos. 5,922,307 and 6,331,292. The products described therein have a pH range from 6.0 to 10.0.
  • Tooth bleaching compositions are directed towards hydrogen peroxide-containing compounds that are maintained at a substantially constant pH range of 6.0-10.0 during the tooth-bleaching procedure in the presence of a calcium chelating agent.
  • thin polymeric strips that are impregnated with bleaching compounds that must be folded onto the teeth and held in place while bleaching.
  • 5,891,453 entitled "Delivery system for a tooth whitener using a strip of material having low flexural stiffness” is directed to a system for delivering a tooth whitening substance to a plurality of adjacent teeth, the delivery system comprising a strip of flexible material having a sufficient flexibility to form a curved shape on a plurality of adjacent teeth and a tooth whitening substance.
  • the strip of material is readily conformable to the teeth surfaces and to interstitial tooth spaces without permanent deformation when the delivery system is placed thereagainst.
  • the tooth whitening substance is applied to the strip of material such that when the delivery system is placed on the surface of the teeth, the substance contacts the surface providing an active onto the surface.
  • the substance also provides adhesive attachment between the strip of material and the surface to hold the delivery system in place for a sufficient amount of time to allow the active to act upon the surface.
  • the method of delivery includes pre-coating the strip of material or having the wearer apply substance to the strip of material and then applying the delivery system to the teeth surfaces.
  • U.S. Patent No. 5,894,017 entitled "Delivery system for an oral care substance using a strip of material having low flexural stiffness" is directed to a delivery system for an oral care substance includes a strip of material having a flexural stiffness less than about 50 grams/centimeter as measured on a Handle-O-Meter per ASTM test method D2923-95.
  • the strip of material is readily conformable without permanent deformation to a shape of a tooth and its adjoining soft tissue when the delivery system is placed thereagainst.
  • the delivery system also includes an oral care substance applied to the strip of material such that when the delivery system is placed on a surface of the tooth and its adjoining soft tissue, the substance contacts the surface providing an active onto the surface.
  • the substance also provides adhesive attachment between the strip of material and the surface to hold the delivery system in place for a sufficient time to allow the active to act upon the surface.
  • a method of delivery includes pre-coating the strip of material, having the wearer apply substance to the strip of material, or having the wearer apply the substance directly to the surface before applying a strip of material.
  • 6,096,328 entitled "Delivery system for an oral care substance using a strip of material having low flexural stiffness" is directed to a system for delivering an oral care substance to the oral surface, the delivery system comprising a strip of flexible material having a sufficient flexibility to form to the contours of the oral surface.
  • the strip of material is readily conformable to oral surfaces without permanent deformation when the delivery system is placed there against.
  • the oral care substance is applied to the strip of material such that when the delivery system is placed on the oral surface the active contacts the surface.
  • the oral care substance also provides adhesive attachment between the strip of material and the oral surface so as to hold the delivery system in place for a sufficient amount of time to allow the active to act upon the oral surface.
  • Methods of delivering the oral care substance to the oral surface include pre-coating the strip of material, having the wearer apply oral care substance to the strip of material, or having the wearer apply the oral care substance directly to the oral surface and immediately applying the strip of material over the applied oral care substance.
  • the invention is directed toward dental bleaching compositions, and methods of using the same.
  • Such compositions include a whitening agent, and a matrix for holding the whitening agent in such a manner that the whitening agent is released to a surface of a tooth to whiten the tooth.
  • An example of such a matrix is a petrolatum, e.g., a solid, white petrolatum.
  • the invention features a composition for whitening one or more teeth.
  • the composition includes a whitening agent, and a petrolatum, e.g., a white petrolatum.
  • the invention features a composition for whitening one or more teeth that includes a peroxide, a solvent, a polyoxyalkylene, a petrolatum, and a polyvinyl pyrrolidone.
  • the invention features a method for whitening one or more teeth. The method includes applying a therapeutically effective amount of a bleaching composition to one or more teeth.
  • the bleaching composition includes a whitening agent and a petrolatum.
  • the bleaching composition is left in contact with the one or more teeth such that the bleaching composition may whiten the one or more teeth.
  • the applying is performed by painting the composition.
  • Other embodiments and/or aspects may include any one of the following or combinations of the following.
  • the petrolatum is present in the composition from about 10 to about 90 weight percent.
  • the petrolatum is a solid at room temperature.
  • the petrolatum comprises white petrolatum.
  • the whitening agent is a peroxide.
  • the peroxide is present in the composition from about 35 to about 70 weight percent.
  • the composition may further include a tackifying agent, for example, a polyvinyl pyrrolidone, a starch, a polyoxyalkylene, or mixtures of these materials.
  • the tackifying agent is present in the composition from about 5 to about 30 weight percent.
  • the composition of may further include a solvent, for example, water, glycerine, propylene glycol, a polyethylene glycol, or mixtures of these materials.
  • the present invention provides a method for treating one or more teeth.
  • the method includes the steps of applying a therapeutically effective amount of a bleaching composition to one or more teeth via a tray, mouthguard, stint, wand applicator or alternative means leaving the bleaching composition in contact with the one or more teeth such that the bleaching composition may whiten the tooth.
  • the invention provides a kit for treating one or more teeth.
  • the kit may include a wand applicator having a cap portion with a threaded configuration and an applicator portion extending from the cap portion; a whitening composition container having an interior space to hold a whitening composition and having a threaded configuration complementary to the threaded configuration of the wand applicator; and a whitening composition within said whitening composition container.
  • a composition for whitening teeth is another embodiment of the invention.
  • the composition may include one or more whitening agents present in an amount from about 3 to about 30 weight percent (3-30% hydrogen peroxide and 9- 45% urea peroxide); one or more tackifying agents present in an amount from about 3 to about 50 weight percent (PVP 3-50% and petrolatum 10-90%); and one or more solubilizing agents present in an amount from about 1 to about 20 weight percent, e.g., about 1 to about 5 weight percent.
  • Another embodiment of the invention is directed to a composition having the following ingredients, listed by weight percent:
  • Another embodiment of the invention is directed to a composition having the following ingredients, listed by weight percent:
  • the bleaching composition has the following formulation:
  • the bleaching composition has the following formulation:
  • Embodiments may have one or more of the following advantages.
  • the bleaching compositions disclosed herein can be applied by a professional, e.g., a dentist, or by a non-dental professional, e.g., a consumer.
  • the bleaching compositions can be applied by a variety of means.
  • a tray, a mouthguard or a stint may be used to apply the bleaching compositions.
  • the bleaching compositions can also be painted directly onto the teeth, for example, by using a brush or a pen. In embodiments where the bleaching compositions are painted on directly by a user, the need for a tray, a mouthguard, or a stint is eliminated, making the bleaching process simpler and more comfortable for the user.
  • Petrolatum has been defined as a semisolid or liquid mixture of hydrocarbons derived by distillation of paraffin- base petroleum fractions.
  • the solid form may be either water- white or pale yellow. Its chief uses are in mild ointments, cosmetics, softener in rubber mixtures and food processing (release agent in bakery products, dehydrated fruits and vegetables), protective coating (raw fruits and vegetables), and defoaming agent (beet sugar, yeast).
  • the liquid form (white mineral oil) is used as a laxative, textile lubricant, and dispersing agent. There are three grades of both solid and liquid types with various specifications. (USP, NF, and FCC). Polyvinyl pyrrolidone (PVP) were also optionally included for several reasons.
  • PVP can enhance the adhesive force of the formulation because of its special side groups along the main chain.
  • PVP is water dissolvable and forms the second phase in the petroleum matrix, which can control the release of peroxide from the matrix.
  • PVP can be optionally added as a viscosity adjusting agent. Based on these considerations, the PVP can be around 5 to 30 percent by weight, preferably about 10 percent by weight.
  • the process to make the formulation as identified below is straight forward - if the solid peroxide agent is used, the peroxide can first be mixed with petrolatum, then the other ingredients defined below, such as polyvinyl pyrrolidone or glycerin can be added to the mixture. Other ingredients, such as flavors, will further be mixed.
  • liquid peroxide solution is used as the whitening agents, surfactant is used to make the homogenous mixture of the hydrophilic ingredients and hydrophobic ingredients.
  • surfactant is used to make the homogenous mixture of the hydrophilic ingredients and hydrophobic ingredients.
  • the gel can be used directly on the teeth without the trays, mouthguards or other holders. If desired, the gel can be used with alkaline gel to further enhance the whitening effect as a two-part whitening system.
  • the bleaching composition has the formulation:
  • the bleaching composition has the following formulation:
  • the bleaching composition has the following formulation:
  • the bleaching composition has the following formulation:
  • the whitening composition may include a whitening agent and a tackifying agent, among other ingredients.
  • Suitable whitening, or bleaching, agents include peroxides, such as hydrogen peroxide, carbamide peroxide or any known whitening compounds suitable for dental applications.
  • Peroxide solutions are commercially available in varying strength, for instance H 2 O 2 is available in strengths from 35 to 70%. The concentration in the composition would vary in accordance with the strength used. Therefore, the weight percent of the solution employed would be adjusted to account for the strength of solution used, as may be appreciated by one skilled in the art.
  • the whitening agent may be present in an amount from 5 to 30 weight percent.
  • a flavor enhancing agent such as peppermint or spearmint oil.
  • a sweetener such as saccharin, or sodium saccharin may be included in the composition. Any suitable flavor enhancing agent or a combination thereof may be included within the whitening composition.
  • These flavoring agents may be present in amounts ranging from trace amounts 0.06 weight percent or less up to about 3 weight percent, or more as desired by the user.
  • Embodiments may include a variety of other ingredients. These ingredients may include a solvent, such as water, glycerin, propylene glycol, polyethylene glycol, or a variety of other compounds suitable for use as solvents for oral applications.
  • the solvent may be present in an amount from about 10 to about 81 weight percent.
  • the composition may also include a solubilizing agent, or emulsifying agent, such as ethoxylated castor oil.
  • a solubilizing agent such as ethoxylated castor oil.
  • emulsifying agent such as ethoxylated castor oil.
  • suitable solubilizing agents include hydrogenated castor oil, or PEG 40 hydrogenated castor oil.
  • the solubilizing agent may be present from about 1.5 to about 20 weight percent, e.g., 1.5 to about 4.25 weight percent.
  • a neutralizing agent such as a hydroxide, for instance, potassium hydroxide, sodium hydroxide, or ammonium hydroxide, may also be added to the composition.
  • Another suitable neutralizing agent is triethanolamine.
  • the neutralizing agent is such that helps to provide a suitable pH for the overall composition.
  • the neutralizing agent may also serve to cross-link the thickening agent or tackifying agent to form a suitable gel.
  • the neutralizing agent is present from about 0.6 to about 5.4 weight percent.
  • the suitable pH ranges from about 5.6 to about 10, e.g., 5.6 to about 7.6.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne une composition permettant de blanchir une ou plusieurs dents, qui comprend un agent de blanchiment et de la vaseline, en particulier de la vaseline blanche. Dans un mode de réalisation de l'invention, la composition comprend un peroxyde, un solvant, un polyoxyalkylène, de la vaseline et une polyvinylpyrrolidone.
EP04780790A 2003-08-13 2004-08-11 Blanchiment dentaire Withdrawn EP1680074A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US49456703P 2003-08-13 2003-08-13
US55903204P 2004-04-05 2004-04-05
US10/914,835 US20050036958A1 (en) 2003-08-13 2004-08-10 Dental bleaching
PCT/US2004/026011 WO2005018592A1 (fr) 2003-08-13 2004-08-11 Blanchiment dentaire

Publications (1)

Publication Number Publication Date
EP1680074A1 true EP1680074A1 (fr) 2006-07-19

Family

ID=34139628

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04780790A Withdrawn EP1680074A1 (fr) 2003-08-13 2004-08-11 Blanchiment dentaire

Country Status (5)

Country Link
EP (1) EP1680074A1 (fr)
JP (1) JP2007502286A (fr)
AU (1) AU2004266635A1 (fr)
BR (1) BRPI0413514A (fr)
CA (1) CA2535379A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8623388B2 (en) * 2009-10-29 2014-01-07 The Procter & Gamble Company Denture care composition
WO2018081003A1 (fr) * 2016-10-26 2018-05-03 The Procter & Gamble Company Source de rayonnement électromagnétique et composition orale à phases multiples pour usage de soins buccaux
JP2022526637A (ja) * 2019-04-16 2022-05-25 ザ プロクター アンド ギャンブル カンパニー 親水性有効成分粒子を含む半固体多相口腔用組成物

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2005018592A1 *

Also Published As

Publication number Publication date
CA2535379A1 (fr) 2005-03-03
AU2004266635A1 (en) 2005-03-03
BRPI0413514A (pt) 2006-10-10
JP2007502286A (ja) 2007-02-08

Similar Documents

Publication Publication Date Title
US6306370B1 (en) Compositions and methods for whitening and desensitizing teeth
US8349298B2 (en) Methods of bleaching teeth using adhesive dental bleaching compositions containing polyvinylpyrrolidone
CA2791549C (fr) Composition pour blanchir les dents
US10517813B2 (en) Kits and methods for cleaning and remineralizing teeth
US20070189983A1 (en) Tooth whitening composition
US20050036958A1 (en) Dental bleaching
MXPA06001677A (es) Sistema blanqueador de dientes hidrofobico y metodos de uso.
JPWO2005063182A1 (ja) 歯牙白色化用非水系ゲル組成物及び歯牙美白用セット
JP3997371B2 (ja) 歯の美白用セット
KR100734581B1 (ko) 치아를 미백 및 탈감각시키기 위한 조성물 및 방법
US20030194383A1 (en) Teeth whitening system
US20050214232A1 (en) Dental whitening
EP1656185A2 (fr) Composition liquide de blanchiment des dents a base de support polymere hydrophobe
EP1680074A1 (fr) Blanchiment dentaire
WO2000028953A1 (fr) Compositions et procedes de blanchiment des dents
US8936778B2 (en) Methods for bleaching and desensitizing teeth
US20050036959A1 (en) Rapid temporary tooth whitening composition
JP4462428B2 (ja) 歯牙美白用セット
US20160151256A1 (en) Oral composition
GB2412316A (en) Peroxide tooth whitening composition
GB2409975A (en) Tooth whitening composition
GB2409976A (en) Tooth whitening composition

Legal Events

Date Code Title Description
PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

Free format text: ORIGINAL CODE: 0009012

17P Request for examination filed

Effective date: 20060313

AK Designated contracting states

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR

DAX Request for extension of the european patent (deleted)
STAA Information on the status of an ep patent application or granted ep patent

Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN

18D Application deemed to be withdrawn

Effective date: 20080303