EP1663178A1 - Fils a base de poly (oxide d'ethylene) et des systemes d'administration de medicaments produits a partir de ces films - Google Patents

Fils a base de poly (oxide d'ethylene) et des systemes d'administration de medicaments produits a partir de ces films

Info

Publication number
EP1663178A1
EP1663178A1 EP04753818A EP04753818A EP1663178A1 EP 1663178 A1 EP1663178 A1 EP 1663178A1 EP 04753818 A EP04753818 A EP 04753818A EP 04753818 A EP04753818 A EP 04753818A EP 1663178 A1 EP1663178 A1 EP 1663178A1
Authority
EP
European Patent Office
Prior art keywords
film
films
water
film product
drying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04753818A
Other languages
German (de)
English (en)
Inventor
Robert K. Yang
Richard C. Fuisz
Gary L. Myers
Joseph M. Fuisz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aquestive Therapeutics Inc
Original Assignee
MonoSol Rx LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MonoSol Rx LLC filed Critical MonoSol Rx LLC
Priority to EP17151005.0A priority Critical patent/EP3210601A1/fr
Priority to EP13189513.8A priority patent/EP2716284A3/fr
Publication of EP1663178A1 publication Critical patent/EP1663178A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J5/00—Manufacture of articles or shaped materials containing macromolecular substances
    • C08J5/18—Manufacture of films or sheets
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2371/00—Characterised by the use of polyethers obtained by reactions forming an ether link in the main chain; Derivatives of such polymers
    • C08J2371/02—Polyalkylene oxides

Abstract

L'invention porte sur des films et leurs procédés de préparation leur conférant une hétérogénéité uniforme non autoagrégatrice. Il est souhaitable que les films se désintègrent dans l'eau et soient obtenus par un procédé de séchage contrôlé en assurant l'uniformité voulue. Un tel film consiste en un composant polymérique d'oxyde de polyéthylène, facultativement mélangé à des polymères cellulosiques hydrophiles. Il est également souhaitable qu'il contienne un agent à activité pharmaceutique et/ou cosmétique dont la variance ne dépasse pas 10 % par unité de surface.
EP04753818A 2003-05-28 2004-05-28 Fils a base de poly (oxide d'ethylene) et des systemes d'administration de medicaments produits a partir de ces films Withdrawn EP1663178A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP17151005.0A EP3210601A1 (fr) 2003-05-28 2004-05-28 Films à base d'oxyde de polyéthylène et systèmes d'administration de médicament fabriqués à partir de ceux-ci
EP13189513.8A EP2716284A3 (fr) 2003-05-28 2004-05-28 Films à base d'oxyde de polyéthylène et systèmes d'administration de médicament fabriqués à partir de ceux-ci

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47390203P 2003-05-28 2003-05-28
PCT/US2004/017076 WO2006031209A1 (fr) 2003-05-28 2004-05-28 Films a base d'oxyde de polyethylene et systemes d'administration de medicaments en etant faits

Related Child Applications (2)

Application Number Title Priority Date Filing Date
EP13189513.8A Division EP2716284A3 (fr) 2003-05-28 2004-05-28 Films à base d'oxyde de polyéthylène et systèmes d'administration de médicament fabriqués à partir de ceux-ci
EP17151005.0A Division EP3210601A1 (fr) 2003-05-28 2004-05-28 Films à base d'oxyde de polyéthylène et systèmes d'administration de médicament fabriqués à partir de ceux-ci

Publications (1)

Publication Number Publication Date
EP1663178A1 true EP1663178A1 (fr) 2006-06-07

Family

ID=35811416

Family Applications (3)

Application Number Title Priority Date Filing Date
EP13189513.8A Withdrawn EP2716284A3 (fr) 2003-05-28 2004-05-28 Films à base d'oxyde de polyéthylène et systèmes d'administration de médicament fabriqués à partir de ceux-ci
EP17151005.0A Withdrawn EP3210601A1 (fr) 2003-05-28 2004-05-28 Films à base d'oxyde de polyéthylène et systèmes d'administration de médicament fabriqués à partir de ceux-ci
EP04753818A Withdrawn EP1663178A1 (fr) 2003-05-28 2004-05-28 Fils a base de poly (oxide d'ethylene) et des systemes d'administration de medicaments produits a partir de ces films

Family Applications Before (2)

Application Number Title Priority Date Filing Date
EP13189513.8A Withdrawn EP2716284A3 (fr) 2003-05-28 2004-05-28 Films à base d'oxyde de polyéthylène et systèmes d'administration de médicament fabriqués à partir de ceux-ci
EP17151005.0A Withdrawn EP3210601A1 (fr) 2003-05-28 2004-05-28 Films à base d'oxyde de polyéthylène et systèmes d'administration de médicament fabriqués à partir de ceux-ci

Country Status (8)

Country Link
EP (3) EP2716284A3 (fr)
JP (1) JP4795962B2 (fr)
CN (2) CN102670568A (fr)
AU (2) AU2004319243B2 (fr)
BR (1) BRPI0410956A (fr)
CA (1) CA2544776C (fr)
NO (1) NO20056060L (fr)
WO (1) WO2006031209A1 (fr)

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US20040234602A1 (en) 2001-09-21 2004-11-25 Gina Fischer Polymer release system
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US20070281003A1 (en) 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US8765167B2 (en) 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US20080050422A1 (en) * 2001-10-12 2008-02-28 Monosolrx, Llc. Method of administering a film product containing a drug
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
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US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
EP1610767B1 (fr) 2003-03-26 2011-01-19 Egalet A/S Systeme de liberation regulee de morphine
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Also Published As

Publication number Publication date
AU2004319243A8 (en) 2008-08-07
EP2716284A2 (fr) 2014-04-09
CA2544776A1 (fr) 2006-03-23
JP2007500252A (ja) 2007-01-11
CN1812773B (zh) 2012-06-27
CN102670568A (zh) 2012-09-19
EP3210601A1 (fr) 2017-08-30
NO20056060L (no) 2006-02-07
AU2010214780A1 (en) 2010-09-23
AU2004319243B2 (en) 2010-06-03
WO2006031209A1 (fr) 2006-03-23
CA2544776C (fr) 2014-04-15
CN1812773A (zh) 2006-08-02
BRPI0410956A (pt) 2006-07-04
EP2716284A3 (fr) 2014-11-05
JP4795962B2 (ja) 2011-10-19
AU2004319243A1 (en) 2006-01-12

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