EP1663144A1 - Preparations a base d'acetonide de triamcinolone et d'acetate d'anecortave pour injection - Google Patents

Preparations a base d'acetonide de triamcinolone et d'acetate d'anecortave pour injection

Info

Publication number
EP1663144A1
EP1663144A1 EP04782985A EP04782985A EP1663144A1 EP 1663144 A1 EP1663144 A1 EP 1663144A1 EP 04782985 A EP04782985 A EP 04782985A EP 04782985 A EP04782985 A EP 04782985A EP 1663144 A1 EP1663144 A1 EP 1663144A1
Authority
EP
European Patent Office
Prior art keywords
suspension composition
injection
eye
anecortave acetate
suspension
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP04782985A
Other languages
German (de)
English (en)
Inventor
Rajni Jani
Ernesto J. Castillo
Wesley Wehsin Han
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alcon Inc
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of EP1663144A1 publication Critical patent/EP1663144A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics

Abstract

L'invention concerne des compositions injectables d'acétonide de triamcinolone ou d'acétate d'anécortave. Ces compositions conviennent particulièrement à une injection dans le segment postérieur de l'oeil en vue du traitement de maladies ophtalmiques.
EP04782985A 2003-09-23 2004-09-02 Preparations a base d'acetonide de triamcinolone et d'acetate d'anecortave pour injection Withdrawn EP1663144A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US50538603P 2003-09-23 2003-09-23
PCT/US2004/028598 WO2005032510A1 (fr) 2003-09-23 2004-09-02 Preparations a base d'acetonide de triamcinolone et d'acetate d'anecortave pour injection

Publications (1)

Publication Number Publication Date
EP1663144A1 true EP1663144A1 (fr) 2006-06-07

Family

ID=34421523

Family Applications (1)

Application Number Title Priority Date Filing Date
EP04782985A Withdrawn EP1663144A1 (fr) 2003-09-23 2004-09-02 Preparations a base d'acetonide de triamcinolone et d'acetate d'anecortave pour injection

Country Status (13)

Country Link
US (1) US20050065137A1 (fr)
EP (1) EP1663144A1 (fr)
JP (1) JP2007506678A (fr)
KR (1) KR20060095974A (fr)
CN (1) CN1852700A (fr)
AR (1) AR045943A1 (fr)
AU (1) AU2004277864A1 (fr)
BR (1) BRPI0414699A (fr)
CA (1) CA2539023A1 (fr)
MX (1) MXPA06003185A (fr)
RU (1) RU2006113593A (fr)
TW (1) TW200518760A (fr)
WO (1) WO2005032510A1 (fr)

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US20050101582A1 (en) 2003-11-12 2005-05-12 Allergan, Inc. Compositions and methods for treating a posterior segment of an eye
US20060094700A1 (en) * 2004-11-02 2006-05-04 Allergan, Inc. Heat sterilization of a steroid in the presence of phosphate
ITRM20050547A1 (it) * 2005-11-04 2007-05-05 Sooft Italia S R L Gel oftalmico composto da triamcinolone acetonide e da un polimero poliacrilico.
US20070202186A1 (en) 2006-02-22 2007-08-30 Iscience Interventional Corporation Apparatus and formulations for suprachoroidal drug delivery
US8197435B2 (en) 2006-05-02 2012-06-12 Emory University Methods and devices for drug delivery to ocular tissue using microneedle
US9161970B2 (en) 2007-12-12 2015-10-20 Allergan, Inc. Dermal filler
CN101959519B (zh) * 2008-03-11 2013-03-20 爱尔康研究有限公司 用于玻璃体内注射的低粘度、高度絮凝的曲安奈德混悬液
TWI580441B (zh) 2008-09-19 2017-05-01 愛爾康研究有限公司 穩定的藥學次微米懸浮液及其形成方法
CN101893619B (zh) * 2010-02-10 2013-11-13 上海蓝怡科技有限公司 改进乳胶悬浊液稳定性的方法
CN103327939B (zh) 2010-10-15 2017-05-24 科尼尔赛德生物医学公司 用于进入眼睛的装置
KR20150083117A (ko) * 2012-11-08 2015-07-16 클리어사이드 바이오메디컬, 인코포레이드 인간 대상체에서 안구 질병을 치료하기 위한 방법 및 장치
CN110302004B (zh) 2013-05-03 2023-04-28 科尼尔赛德生物医学公司 用于眼部注射的设备和方法
WO2014197317A1 (fr) 2013-06-03 2014-12-11 Clearside Biomedical, Inc. Appareil et procédés pour une administration de médicament à l'aide de multiples réservoirs
MX2016017028A (es) 2014-06-20 2017-08-07 Clearside Biomedical Inc Canula de diametro variable y metodos para el control de la profundidad de insercion para administracion de medicamentos.
USD750223S1 (en) 2014-10-14 2016-02-23 Clearside Biomedical, Inc. Medical injector for ocular injection
EP3413851B1 (fr) 2016-02-10 2023-09-27 Clearside Biomedical, Inc. Emballage
CA3062845A1 (fr) 2016-05-02 2017-11-09 Clearside Biomedical, Inc. Systemes et methodes pour l'administration de medicaments par voie ophtalmique
US10973681B2 (en) 2016-08-12 2021-04-13 Clearside Biomedical, Inc. Devices and methods for adjusting the insertion depth of a needle for medicament delivery
US11701368B2 (en) 2018-01-10 2023-07-18 Eye Co Pty Ltd Unit dose pharmaceutical of a dry powder of one or more glucocorticoid or mineralocorticoid fludrocortisone acetate and/or triamcinolone acetonide comprised in a syringe

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US4771042A (en) * 1985-11-25 1988-09-13 The Upjohn Company Inhibition of angiogenesis involving the coadministration of steroids with heparin or heparin fragments
US5407926A (en) * 1987-12-29 1995-04-18 Alcon Laboratories, Inc. Ophthalmic composition
US4876250A (en) * 1988-10-31 1989-10-24 Alcon Laboratories, Inc. Methods for controlling ocular hypertension with angiostatic steroids
US5192535A (en) * 1988-02-08 1993-03-09 Insite Vision Incorporated Ophthalmic suspensions
US5972922A (en) * 1990-06-11 1999-10-26 Alcon Laboratories, Inc. Steroids which inhibit angiogenesis
US5770592A (en) * 1991-11-22 1998-06-23 Alcon Laboratories, Inc. Prevention and treatment of ocular neovascularization using angiostatic steroids
US5679666A (en) * 1991-11-22 1997-10-21 Alcon Laboratories, Inc. Prevention and treatment of ocular neovascularization by treatment with angiostatic steroids
US5474985A (en) * 1993-12-22 1995-12-12 The Regents Of The University Of California Preventing and treating elevated intraocular pressure associated with administered or endogenous steroids using non-steroidal cyclooxygenase inhibitors
US6172054B1 (en) * 1995-06-15 2001-01-09 Alcon Laboratories, Inc. Combination therapy for lowering and controlling intraocular pressure
EP0995435B1 (fr) * 1997-05-14 2007-04-25 Senju Pharmaceutical Co., Ltd. Preparations a base de suspensions aqueuses possedant d'excellentes proprietes de redispersion
US6011023A (en) * 1997-08-27 2000-01-04 Alcon Laboratories, Inc. Angiostatic steroids
US6428814B1 (en) * 1999-10-08 2002-08-06 Elan Pharma International Ltd. Bioadhesive nanoparticulate compositions having cationic surface stabilizers
PL203797B1 (pl) * 1999-04-09 2009-11-30 Ortho Mcneil Pharm Inc Kompozycje farmaceutyczne erytropoetyny
US6696426B2 (en) * 2000-08-22 2004-02-24 Pharmacia Corporation Preservative free ophthalmic oxazolidinone antibiotic drug delivery systems
ES2396598T3 (es) * 2000-08-25 2013-02-22 Senju Pharmaceutical Co., Ltd. Preparaciones en forma de suspensiones acuosas
CA2436418A1 (fr) * 2001-01-30 2002-08-08 Board Of Regents, The University Of Texas Systems Procede de production de nanoparticules et de microparticules par congelation par pulverisation dans un liquide
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Title
See references of WO2005032510A1 *

Also Published As

Publication number Publication date
WO2005032510A1 (fr) 2005-04-14
JP2007506678A (ja) 2007-03-22
RU2006113593A (ru) 2006-08-27
AR045943A1 (es) 2005-11-16
MXPA06003185A (es) 2006-06-23
CA2539023A1 (fr) 2005-04-14
TW200518760A (en) 2005-06-16
BRPI0414699A (pt) 2006-11-28
CN1852700A (zh) 2006-10-25
US20050065137A1 (en) 2005-03-24
AU2004277864A1 (en) 2005-04-14
KR20060095974A (ko) 2006-09-05

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