WO2005032510A1 - Triamcinolone acetonide and anecortave acetate formulations for injection - Google Patents
Triamcinolone acetonide and anecortave acetate formulations for injection Download PDFInfo
- Publication number
- WO2005032510A1 WO2005032510A1 PCT/US2004/028598 US2004028598W WO2005032510A1 WO 2005032510 A1 WO2005032510 A1 WO 2005032510A1 US 2004028598 W US2004028598 W US 2004028598W WO 2005032510 A1 WO2005032510 A1 WO 2005032510A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- suspension composition
- injection
- eye
- anecortave acetate
- suspension
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2006526921A JP2007506678A (en) | 2003-09-23 | 2004-09-02 | Formulation of triamcinolone acetanide and anecoltab acetate for injection |
AU2004277864A AU2004277864A1 (en) | 2003-09-23 | 2004-09-02 | Triamcinolone acetonide and anecortave acetate formulations for injection |
EP04782985A EP1663144A1 (en) | 2003-09-23 | 2004-09-02 | Triamcinolone acetonide and anecortave acetate formulations for injection |
CA002539023A CA2539023A1 (en) | 2003-09-23 | 2004-09-02 | Triamcinolone acetonide and anecortave acetate formulations for injection |
MXPA06003185A MXPA06003185A (en) | 2003-09-23 | 2004-09-02 | Triamcinolone acetonide and anecortave acetate formulations for injection. |
BRPI0414699-9A BRPI0414699A (en) | 2003-09-23 | 2004-09-02 | anecortave acetate and triamcinolone acetonide formulations for injection |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50538603P | 2003-09-23 | 2003-09-23 | |
US60/505,386 | 2003-09-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2005032510A1 true WO2005032510A1 (en) | 2005-04-14 |
Family
ID=34421523
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2004/028598 WO2005032510A1 (en) | 2003-09-23 | 2004-09-02 | Triamcinolone acetonide and anecortave acetate formulations for injection |
Country Status (13)
Country | Link |
---|---|
US (1) | US20050065137A1 (en) |
EP (1) | EP1663144A1 (en) |
JP (1) | JP2007506678A (en) |
KR (1) | KR20060095974A (en) |
CN (1) | CN1852700A (en) |
AR (1) | AR045943A1 (en) |
AU (1) | AU2004277864A1 (en) |
BR (1) | BRPI0414699A (en) |
CA (1) | CA2539023A1 (en) |
MX (1) | MXPA06003185A (en) |
RU (1) | RU2006113593A (en) |
TW (1) | TW200518760A (en) |
WO (1) | WO2005032510A1 (en) |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1782795A1 (en) * | 2005-11-04 | 2007-05-09 | Sooft Italia SRL | Ophthalmic gel made up of triamcinolone acetonide and a polyacrylic polymer |
WO2009114521A1 (en) * | 2008-03-11 | 2009-09-17 | Alcon Research, Ltd. | Low viscosity, highly flocculated triamcinolone acetonide suspensions for intravitreal injection |
WO2010033528A1 (en) | 2008-09-19 | 2010-03-25 | Alcon Research, Ltd. | Stabilized pharmaceutical sub-micron suspensions and methods of forming same |
WO2019136512A1 (en) * | 2018-01-10 | 2019-07-18 | Eye Co Pty Ltd | Medical device and pharmaceutical composition for treatment of an eye disease or condition |
US10517756B2 (en) | 2013-05-03 | 2019-12-31 | Clearside Biomedical, Inc | Apparatus and methods for ocular injection |
US10952894B2 (en) | 2010-10-15 | 2021-03-23 | Clearside Biomedical, Inc. | Device for ocular access |
US10973681B2 (en) | 2016-08-12 | 2021-04-13 | Clearside Biomedical, Inc. | Devices and methods for adjusting the insertion depth of a needle for medicament delivery |
US11596545B2 (en) | 2016-05-02 | 2023-03-07 | Clearside Biomedical, Inc. | Systems and methods for ocular drug delivery |
US11752101B2 (en) | 2006-02-22 | 2023-09-12 | Clearside Biomedical, Inc. | Ocular injector and methods for accessing suprachoroidal space of the eye |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070224278A1 (en) * | 2003-11-12 | 2007-09-27 | Lyons Robert T | Low immunogenicity corticosteroid compositions |
US20050101582A1 (en) * | 2003-11-12 | 2005-05-12 | Allergan, Inc. | Compositions and methods for treating a posterior segment of an eye |
WO2006043965A1 (en) * | 2004-10-14 | 2006-04-27 | Allergan, Inc. | Therapeutic ophthalmic compositions containing retinal friendly excipients and related methods |
US20060094700A1 (en) * | 2004-11-02 | 2006-05-04 | Allergan, Inc. | Heat sterilization of a steroid in the presence of phosphate |
US8197435B2 (en) | 2006-05-02 | 2012-06-12 | Emory University | Methods and devices for drug delivery to ocular tissue using microneedle |
US9161970B2 (en) | 2007-12-12 | 2015-10-20 | Allergan, Inc. | Dermal filler |
CN101893619B (en) * | 2010-02-10 | 2013-11-13 | 上海蓝怡科技有限公司 | Method for improving stability of latex suspension liquid |
BR112015010566A2 (en) | 2012-11-08 | 2017-07-11 | Clearside Biomedical Inc | methods and devices for the treatment of eye disease in human subjects |
US10188550B2 (en) | 2013-06-03 | 2019-01-29 | Clearside Biomedical, Inc. | Apparatus and methods for drug delivery using multiple reservoirs |
RU2710491C2 (en) | 2014-06-20 | 2019-12-26 | Клиасайд Байомедикал, Инк. | Device for drug injection into ocular tissue and method for drug injection into ocular tissue |
USD750223S1 (en) | 2014-10-14 | 2016-02-23 | Clearside Biomedical, Inc. | Medical injector for ocular injection |
US10390901B2 (en) | 2016-02-10 | 2019-08-27 | Clearside Biomedical, Inc. | Ocular injection kit, packaging, and methods of use |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030041602A1 (en) * | 2001-01-30 | 2003-03-06 | Williams Robert O. | Process for production of nanoparticles and microparticles by spray freezing into liquid |
US20030129242A1 (en) * | 2002-01-04 | 2003-07-10 | Bosch H. William | Sterile filtered nanoparticulate formulations of budesonide and beclomethasone having tyloxapol as a surface stabilizer |
WO2004073607A2 (en) * | 2003-02-20 | 2004-09-02 | Alcon, Inc. | Use of steroids to treat ocular disorders |
US20040186084A1 (en) * | 2003-03-21 | 2004-09-23 | Akorn, Inc. | Triamcinolone formulations and methods for their preparation and use |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4975537A (en) * | 1985-10-23 | 1990-12-04 | The Upjohn Company | Δ9(11) -angiostatic steroids |
US4771042A (en) * | 1985-11-25 | 1988-09-13 | The Upjohn Company | Inhibition of angiogenesis involving the coadministration of steroids with heparin or heparin fragments |
US5407926A (en) * | 1987-12-29 | 1995-04-18 | Alcon Laboratories, Inc. | Ophthalmic composition |
US4876250A (en) * | 1988-10-31 | 1989-10-24 | Alcon Laboratories, Inc. | Methods for controlling ocular hypertension with angiostatic steroids |
US5192535A (en) * | 1988-02-08 | 1993-03-09 | Insite Vision Incorporated | Ophthalmic suspensions |
US5972922A (en) * | 1990-06-11 | 1999-10-26 | Alcon Laboratories, Inc. | Steroids which inhibit angiogenesis |
US5679666A (en) * | 1991-11-22 | 1997-10-21 | Alcon Laboratories, Inc. | Prevention and treatment of ocular neovascularization by treatment with angiostatic steroids |
US5770592A (en) * | 1991-11-22 | 1998-06-23 | Alcon Laboratories, Inc. | Prevention and treatment of ocular neovascularization using angiostatic steroids |
US5474985A (en) * | 1993-12-22 | 1995-12-12 | The Regents Of The University Of California | Preventing and treating elevated intraocular pressure associated with administered or endogenous steroids using non-steroidal cyclooxygenase inhibitors |
US6172054B1 (en) * | 1995-06-15 | 2001-01-09 | Alcon Laboratories, Inc. | Combination therapy for lowering and controlling intraocular pressure |
DE69837664T2 (en) * | 1997-05-14 | 2008-01-03 | Senju Pharmaceutical Co., Ltd. | AQUEOUS SUSPENSION PREPARATIONS WITH EXCELLENT REDISPERSIBILITY |
US6011023A (en) * | 1997-08-27 | 2000-01-04 | Alcon Laboratories, Inc. | Angiostatic steroids |
US6428814B1 (en) * | 1999-10-08 | 2002-08-06 | Elan Pharma International Ltd. | Bioadhesive nanoparticulate compositions having cationic surface stabilizers |
ATE401908T1 (en) * | 1999-04-09 | 2008-08-15 | Ortho Mcneil Pharm Inc | PHARMACEUTICAL COMPOSITIONS OF ERYTHROPOIETIN |
US6696426B2 (en) * | 2000-08-22 | 2004-02-24 | Pharmacia Corporation | Preservative free ophthalmic oxazolidinone antibiotic drug delivery systems |
EP1312356B1 (en) * | 2000-08-25 | 2012-10-17 | Senju Pharmaceutical Co., Ltd. | Aqueous suspension preparations |
US20060166956A1 (en) * | 2002-08-05 | 2006-07-27 | Jerdan Janice A | Use of anecortave acetate for the protection of visual acuity in patients with age related macular degeneration |
ZA200505990B (en) * | 2003-02-20 | 2006-12-27 | Alcon Inc | Formulations of glucocorticoids to treat pathologic ocular angiogenesis |
-
2004
- 2004-09-02 JP JP2006526921A patent/JP2007506678A/en not_active Withdrawn
- 2004-09-02 MX MXPA06003185A patent/MXPA06003185A/en not_active Application Discontinuation
- 2004-09-02 CN CNA2004800264396A patent/CN1852700A/en active Pending
- 2004-09-02 CA CA002539023A patent/CA2539023A1/en not_active Abandoned
- 2004-09-02 WO PCT/US2004/028598 patent/WO2005032510A1/en active Application Filing
- 2004-09-02 AU AU2004277864A patent/AU2004277864A1/en not_active Abandoned
- 2004-09-02 RU RU2006113593/15A patent/RU2006113593A/en not_active Application Discontinuation
- 2004-09-02 BR BRPI0414699-9A patent/BRPI0414699A/en not_active IP Right Cessation
- 2004-09-02 US US10/933,006 patent/US20050065137A1/en not_active Abandoned
- 2004-09-02 KR KR1020067005546A patent/KR20060095974A/en not_active Application Discontinuation
- 2004-09-02 EP EP04782985A patent/EP1663144A1/en not_active Withdrawn
- 2004-09-13 TW TW093127639A patent/TW200518760A/en unknown
- 2004-09-22 AR ARP040103418A patent/AR045943A1/en unknown
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030041602A1 (en) * | 2001-01-30 | 2003-03-06 | Williams Robert O. | Process for production of nanoparticles and microparticles by spray freezing into liquid |
US20030129242A1 (en) * | 2002-01-04 | 2003-07-10 | Bosch H. William | Sterile filtered nanoparticulate formulations of budesonide and beclomethasone having tyloxapol as a surface stabilizer |
WO2004073607A2 (en) * | 2003-02-20 | 2004-09-02 | Alcon, Inc. | Use of steroids to treat ocular disorders |
US20040186084A1 (en) * | 2003-03-21 | 2004-09-23 | Akorn, Inc. | Triamcinolone formulations and methods for their preparation and use |
Cited By (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1782795A1 (en) * | 2005-11-04 | 2007-05-09 | Sooft Italia SRL | Ophthalmic gel made up of triamcinolone acetonide and a polyacrylic polymer |
US11944703B2 (en) | 2006-02-22 | 2024-04-02 | Clearside Biomedical, Inc. | Ocular injector and methods for accessing suprachoroidal space of the eye |
US11752101B2 (en) | 2006-02-22 | 2023-09-12 | Clearside Biomedical, Inc. | Ocular injector and methods for accessing suprachoroidal space of the eye |
KR101555293B1 (en) | 2008-03-11 | 2015-10-06 | 알콘 리서치, 리미티드 | Low viscosity, highly flocculated triamcinolone acetonide suspensions for intravitreal injection |
WO2009114521A1 (en) * | 2008-03-11 | 2009-09-17 | Alcon Research, Ltd. | Low viscosity, highly flocculated triamcinolone acetonide suspensions for intravitreal injection |
US8128960B2 (en) | 2008-03-11 | 2012-03-06 | Alcon Research, Ltd. | Low viscosity, highly flocculated triamcinolone acetonide suspensions for intravitreal injection |
US8211880B2 (en) | 2008-03-11 | 2012-07-03 | Alcon Research, Ltd. | Low viscosity, highly flocculated triamcinolone acetonide suspensions for intravitreal injection |
RU2481842C2 (en) * | 2008-03-11 | 2013-05-20 | Алькон Рисерч, Лтд. | Low-viscous highly flocculated triamcinolone acetonide suspensions for intravitreal injections |
TWI468165B (en) * | 2008-03-11 | 2015-01-11 | Alcon Res Ltd | Low viscosity, highly flocculated triamcinolone acetonide suspensions for intravitreal injection |
AU2009293400B2 (en) * | 2008-09-19 | 2015-05-07 | Novartis Ag | Stabilized pharmaceutical sub-micron suspensions and methods of forming same |
EP2425815A1 (en) * | 2008-09-19 | 2012-03-07 | Alcon Research, Ltd. | Stabilized pharmaceutical sub-micron suspensions and methods of forming same |
WO2010033528A1 (en) | 2008-09-19 | 2010-03-25 | Alcon Research, Ltd. | Stabilized pharmaceutical sub-micron suspensions and methods of forming same |
US10952894B2 (en) | 2010-10-15 | 2021-03-23 | Clearside Biomedical, Inc. | Device for ocular access |
US10517756B2 (en) | 2013-05-03 | 2019-12-31 | Clearside Biomedical, Inc | Apparatus and methods for ocular injection |
US10555833B2 (en) | 2013-05-03 | 2020-02-11 | Clearside Biomedical, Inc. | Apparatus and methods for ocular injection |
US10722396B2 (en) | 2013-05-03 | 2020-07-28 | Clearside Biomedical., Inc. | Apparatus and methods for ocular injection |
US11559428B2 (en) | 2013-05-03 | 2023-01-24 | Clearside Biomedical, Inc. | Apparatus and methods for ocular injection |
US11596545B2 (en) | 2016-05-02 | 2023-03-07 | Clearside Biomedical, Inc. | Systems and methods for ocular drug delivery |
US10973681B2 (en) | 2016-08-12 | 2021-04-13 | Clearside Biomedical, Inc. | Devices and methods for adjusting the insertion depth of a needle for medicament delivery |
US11701368B2 (en) | 2018-01-10 | 2023-07-18 | Eye Co Pty Ltd | Unit dose pharmaceutical of a dry powder of one or more glucocorticoid or mineralocorticoid fludrocortisone acetate and/or triamcinolone acetonide comprised in a syringe |
WO2019136512A1 (en) * | 2018-01-10 | 2019-07-18 | Eye Co Pty Ltd | Medical device and pharmaceutical composition for treatment of an eye disease or condition |
Also Published As
Publication number | Publication date |
---|---|
CN1852700A (en) | 2006-10-25 |
TW200518760A (en) | 2005-06-16 |
MXPA06003185A (en) | 2006-06-23 |
RU2006113593A (en) | 2006-08-27 |
BRPI0414699A (en) | 2006-11-28 |
US20050065137A1 (en) | 2005-03-24 |
AU2004277864A1 (en) | 2005-04-14 |
JP2007506678A (en) | 2007-03-22 |
KR20060095974A (en) | 2006-09-05 |
CA2539023A1 (en) | 2005-04-14 |
EP1663144A1 (en) | 2006-06-07 |
AR045943A1 (en) | 2005-11-16 |
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