EP1613154A2 - Solid pest control system - Google Patents
Solid pest control systemInfo
- Publication number
- EP1613154A2 EP1613154A2 EP04758580A EP04758580A EP1613154A2 EP 1613154 A2 EP1613154 A2 EP 1613154A2 EP 04758580 A EP04758580 A EP 04758580A EP 04758580 A EP04758580 A EP 04758580A EP 1613154 A2 EP1613154 A2 EP 1613154A2
- Authority
- EP
- European Patent Office
- Prior art keywords
- copolymer
- fatty acid
- active agent
- formulation according
- polymeric formulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000007787 solid Substances 0.000 title claims abstract description 33
- 241000607479 Yersinia pestis Species 0.000 title claims abstract description 29
- 229920000642 polymer Polymers 0.000 claims abstract description 47
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract description 40
- 239000000194 fatty acid Substances 0.000 claims abstract description 40
- 229930195729 fatty acid Natural products 0.000 claims abstract description 40
- 150000004665 fatty acids Chemical class 0.000 claims abstract description 40
- 229920001577 copolymer Polymers 0.000 claims abstract description 34
- 239000000203 mixture Substances 0.000 claims description 64
- 239000013543 active substance Substances 0.000 claims description 34
- 238000009472 formulation Methods 0.000 claims description 34
- 238000000034 method Methods 0.000 claims description 25
- 235000021355 Stearic acid Nutrition 0.000 claims description 22
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims description 22
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims description 22
- 239000008117 stearic acid Substances 0.000 claims description 22
- 238000002844 melting Methods 0.000 claims description 21
- 230000008018 melting Effects 0.000 claims description 20
- 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 claims description 10
- -1 polyethylene Polymers 0.000 claims description 10
- 239000000843 powder Substances 0.000 claims description 10
- 239000007788 liquid Substances 0.000 claims description 9
- 239000002245 particle Substances 0.000 claims description 8
- 241001465754 Metazoa Species 0.000 claims description 7
- 239000005038 ethylene vinyl acetate Substances 0.000 claims description 7
- 239000008187 granular material Substances 0.000 claims description 7
- NIQCNGHVCWTJSM-UHFFFAOYSA-N Dimethyl phthalate Chemical compound COC(=O)C1=CC=CC=C1C(=O)OC NIQCNGHVCWTJSM-UHFFFAOYSA-N 0.000 claims description 6
- SESFRYSPDFLNCH-UHFFFAOYSA-N benzyl benzoate Chemical compound C=1C=CC=CC=1C(=O)OCC1=CC=CC=C1 SESFRYSPDFLNCH-UHFFFAOYSA-N 0.000 claims description 6
- NYPJDWWKZLNGGM-UHFFFAOYSA-N fenvalerate Chemical compound C=1C=C(Cl)C=CC=1C(C(C)C)C(=O)OC(C#N)C(C=1)=CC=CC=1OC1=CC=CC=C1 NYPJDWWKZLNGGM-UHFFFAOYSA-N 0.000 claims description 6
- 229920002689 polyvinyl acetate Polymers 0.000 claims description 6
- 239000011118 polyvinyl acetate Substances 0.000 claims description 6
- 239000004480 active ingredient Substances 0.000 claims description 5
- 239000008188 pellet Substances 0.000 claims description 5
- 229960000490 permethrin Drugs 0.000 claims description 5
- RLLPVAHGXHCWKJ-UHFFFAOYSA-N permethrin Chemical compound CC1(C)C(C=C(Cl)Cl)C1C(=O)OCC1=CC=CC(OC=2C=CC=CC=2)=C1 RLLPVAHGXHCWKJ-UHFFFAOYSA-N 0.000 claims description 5
- 239000005871 repellent Substances 0.000 claims description 5
- 230000002940 repellent Effects 0.000 claims description 5
- 241000238631 Hexapoda Species 0.000 claims description 4
- 239000004698 Polyethylene Substances 0.000 claims description 4
- 239000002728 pyrethroid Substances 0.000 claims description 4
- ZCVAOQKBXKSDMS-AQYZNVCMSA-N (+)-trans-allethrin Chemical compound CC1(C)[C@H](C=C(C)C)[C@H]1C(=O)OC1C(C)=C(CC=C)C(=O)C1 ZCVAOQKBXKSDMS-AQYZNVCMSA-N 0.000 claims description 3
- CXBMCYHAMVGWJQ-CABCVRRESA-N (1,3-dioxo-4,5,6,7-tetrahydroisoindol-2-yl)methyl (1r,3r)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate Chemical compound CC1(C)[C@H](C=C(C)C)[C@H]1C(=O)OCN1C(=O)C(CCCC2)=C2C1=O CXBMCYHAMVGWJQ-CABCVRRESA-N 0.000 claims description 3
- OBDKTQFLFFCZBN-UHFFFAOYSA-N 1-(cyclohepten-1-yl)-2-octylcycloheptene Chemical compound C1CCCCC(CCCCCCCC)=C1C1=CCCCCC1 OBDKTQFLFFCZBN-UHFFFAOYSA-N 0.000 claims description 3
- FMTFEIJHMMQUJI-NJAFHUGGSA-N 102130-98-3 Natural products CC=CCC1=C(C)[C@H](CC1=O)OC(=O)[C@@H]1[C@@H](C=C(C)C)C1(C)C FMTFEIJHMMQUJI-NJAFHUGGSA-N 0.000 claims description 3
- KXPXKNBDCUOENF-UHFFFAOYSA-N 2-(Octylthio)ethanol Chemical compound CCCCCCCCSCCO KXPXKNBDCUOENF-UHFFFAOYSA-N 0.000 claims description 3
- XNYGOEGATLFFOX-UHFFFAOYSA-N 4,5a,6,9,9a,9b-hexahydro-1h-dibenzofuran-4a-carbaldehyde Chemical compound C12CC=CCC2OC2(C=O)C1CC=CC2 XNYGOEGATLFFOX-UHFFFAOYSA-N 0.000 claims description 3
- FIPWRIJSWJWJAI-UHFFFAOYSA-N Butyl carbitol 6-propylpiperonyl ether Chemical compound C1=C(CCC)C(COCCOCCOCCCC)=CC2=C1OCO2 FIPWRIJSWJWJAI-UHFFFAOYSA-N 0.000 claims description 3
- 235000019499 Citrus oil Nutrition 0.000 claims description 3
- 239000005946 Cypermethrin Substances 0.000 claims description 3
- 239000006001 Methyl nonyl ketone Substances 0.000 claims description 3
- MMOXZBCLCQITDF-UHFFFAOYSA-N N,N-diethyl-m-toluamide Chemical compound CCN(CC)C(=O)C1=CC=CC(C)=C1 MMOXZBCLCQITDF-UHFFFAOYSA-N 0.000 claims description 3
- 239000002174 Styrene-butadiene Substances 0.000 claims description 3
- KMPQYAYAQWNLME-UHFFFAOYSA-N Undecanal Natural products CCCCCCCCCCC=O KMPQYAYAQWNLME-UHFFFAOYSA-N 0.000 claims description 3
- VXSIXFKKSNGRRO-MXOVTSAMSA-N [(1s)-2-methyl-4-oxo-3-[(2z)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1r,3r)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate;[(1s)-2-methyl-4-oxo-3-[(2z)-penta-2,4-dienyl]cyclopent-2-en-1-yl] (1r,3r)-3-[(e)-3-methoxy-2-methyl-3-oxoprop-1-enyl Chemical class CC1(C)[C@H](C=C(C)C)[C@H]1C(=O)O[C@@H]1C(C)=C(C\C=C/C=C)C(=O)C1.CC1(C)[C@H](/C=C(\C)C(=O)OC)[C@H]1C(=O)O[C@@H]1C(C)=C(C\C=C/C=C)C(=O)C1 VXSIXFKKSNGRRO-MXOVTSAMSA-N 0.000 claims description 3
- 230000000895 acaricidal effect Effects 0.000 claims description 3
- 239000000642 acaricide Substances 0.000 claims description 3
- 239000002253 acid Substances 0.000 claims description 3
- 229940024113 allethrin Drugs 0.000 claims description 3
- 230000000844 anti-bacterial effect Effects 0.000 claims description 3
- 239000005667 attractant Substances 0.000 claims description 3
- 239000003899 bactericide agent Substances 0.000 claims description 3
- 229960002903 benzyl benzoate Drugs 0.000 claims description 3
- 229950002373 bioresmethrin Drugs 0.000 claims description 3
- VEMKTZHHVJILDY-UXHICEINSA-N bioresmethrin Chemical compound CC1(C)[C@H](C=C(C)C)[C@H]1C(=O)OCC1=COC(CC=2C=CC=CC=2)=C1 VEMKTZHHVJILDY-UXHICEINSA-N 0.000 claims description 3
- MTAZNLWOLGHBHU-UHFFFAOYSA-N butadiene-styrene rubber Chemical compound C=CC=C.C=CC1=CC=CC=C1 MTAZNLWOLGHBHU-UHFFFAOYSA-N 0.000 claims description 3
- 125000004432 carbon atom Chemical group C* 0.000 claims description 3
- 239000010632 citronella oil Substances 0.000 claims description 3
- 239000010500 citrus oil Substances 0.000 claims description 3
- ZXQYGBMAQZUVMI-UNOMPAQXSA-N cyhalothrin Chemical compound CC1(C)C(\C=C(/Cl)C(F)(F)F)C1C(=O)OC(C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 ZXQYGBMAQZUVMI-UNOMPAQXSA-N 0.000 claims description 3
- 229960005424 cypermethrin Drugs 0.000 claims description 3
- KAATUXNTWXVJKI-UHFFFAOYSA-N cypermethrin Chemical compound CC1(C)C(C=C(Cl)Cl)C1C(=O)OC(C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 KAATUXNTWXVJKI-UHFFFAOYSA-N 0.000 claims description 3
- 229960002483 decamethrin Drugs 0.000 claims description 3
- OWZREIFADZCYQD-NSHGMRRFSA-N deltamethrin Chemical compound CC1(C)[C@@H](C=C(Br)Br)[C@H]1C(=O)O[C@H](C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 OWZREIFADZCYQD-NSHGMRRFSA-N 0.000 claims description 3
- OEBRKCOSUFCWJD-UHFFFAOYSA-N dichlorvos Chemical compound COP(=O)(OC)OC=C(Cl)Cl OEBRKCOSUFCWJD-UHFFFAOYSA-N 0.000 claims description 3
- 229950001327 dichlorvos Drugs 0.000 claims description 3
- FBSAITBEAPNWJG-UHFFFAOYSA-N dimethyl phthalate Natural products CC(=O)OC1=CC=CC=C1OC(C)=O FBSAITBEAPNWJG-UHFFFAOYSA-N 0.000 claims description 3
- 229960004118 dimethylcarbate Drugs 0.000 claims description 3
- VGQLNJWOULYVFV-SPJNRGJMSA-N dimethylcarbate Chemical compound C1[C@H]2C=C[C@@H]1[C@H](C(=O)OC)[C@@H]2C(=O)OC VGQLNJWOULYVFV-SPJNRGJMSA-N 0.000 claims description 3
- 229960001826 dimethylphthalate Drugs 0.000 claims description 3
- IITCWRFYJWUUPC-UHFFFAOYSA-N dipropyl pyridine-2,5-dicarboxylate Chemical compound CCCOC(=O)C1=CC=C(C(=O)OCCC)N=C1 IITCWRFYJWUUPC-UHFFFAOYSA-N 0.000 claims description 3
- QHZOMAXECYYXGP-UHFFFAOYSA-N ethene;prop-2-enoic acid Chemical class C=C.OC(=O)C=C QHZOMAXECYYXGP-UHFFFAOYSA-N 0.000 claims description 3
- JCLHQFUTFHUXNN-UHFFFAOYSA-N ethyl biscoumacetate Chemical compound C1=CC=C2OC(=O)C(C(C=3C(OC4=CC=CC=C4C=3O)=O)C(=O)OCC)=C(O)C2=C1 JCLHQFUTFHUXNN-UHFFFAOYSA-N 0.000 claims description 3
- 239000000417 fungicide Substances 0.000 claims description 3
- 239000002917 insecticide Substances 0.000 claims description 3
- ZWDZJRRQSXLOQR-UHFFFAOYSA-N n-butyl-n-phenylacetamide Chemical compound CCCCN(C(C)=O)C1=CC=CC=C1 ZWDZJRRQSXLOQR-UHFFFAOYSA-N 0.000 claims description 3
- IPCSVZSSVZVIGE-UHFFFAOYSA-N palmitic acid group Chemical group C(CCCCCCCCCCCCCCC)(=O)O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 claims description 3
- 239000010665 pine oil Substances 0.000 claims description 3
- 229960005235 piperonyl butoxide Drugs 0.000 claims description 3
- 229920002037 poly(vinyl butyral) polymer Polymers 0.000 claims description 3
- 229920000573 polyethylene Polymers 0.000 claims description 3
- 229920002635 polyurethane Polymers 0.000 claims description 3
- 239000004814 polyurethane Substances 0.000 claims description 3
- 238000012545 processing Methods 0.000 claims description 3
- HYJYGLGUBUDSLJ-UHFFFAOYSA-N pyrethrin Natural products CCC(=O)OC1CC(=C)C2CC3OC3(C)C2C2OC(=O)C(=C)C12 HYJYGLGUBUDSLJ-UHFFFAOYSA-N 0.000 claims description 3
- 229940070846 pyrethrins Drugs 0.000 claims description 3
- 229940108410 resmethrin Drugs 0.000 claims description 3
- VEMKTZHHVJILDY-FIWHBWSRSA-N resmethrin Chemical compound CC1(C)[C@H](C=C(C)C)C1C(=O)OCC1=COC(CC=2C=CC=CC=2)=C1 VEMKTZHHVJILDY-FIWHBWSRSA-N 0.000 claims description 3
- 239000011115 styrene butadiene Substances 0.000 claims description 3
- 229920003048 styrene butadiene rubber Polymers 0.000 claims description 3
- UBCKGWBNUIFUST-YHYXMXQVSA-N tetrachlorvinphos Chemical compound COP(=O)(OC)O\C(=C/Cl)C1=CC(Cl)=C(Cl)C=C1Cl UBCKGWBNUIFUST-YHYXMXQVSA-N 0.000 claims description 3
- 229960005199 tetramethrin Drugs 0.000 claims description 3
- KYWIYKKSMDLRDC-UHFFFAOYSA-N undecan-2-one Chemical compound CCCCCCCCCC(C)=O KYWIYKKSMDLRDC-UHFFFAOYSA-N 0.000 claims description 3
- 238000010438 heat treatment Methods 0.000 claims description 2
- 230000002194 synthesizing effect Effects 0.000 claims description 2
- 229960005286 carbaryl Drugs 0.000 claims 2
- CVXBEEMKQHEXEN-UHFFFAOYSA-N carbaryl Chemical compound C1=CC=C2C(OC(=O)NC)=CC=CC2=C1 CVXBEEMKQHEXEN-UHFFFAOYSA-N 0.000 claims 2
- 239000013020 final formulation Substances 0.000 claims 2
- BUYMVQAILCEWRR-UHFFFAOYSA-N naled Chemical compound COP(=O)(OC)OC(Br)C(Cl)(Cl)Br BUYMVQAILCEWRR-UHFFFAOYSA-N 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 abstract description 6
- 241000282472 Canis lupus familiaris Species 0.000 description 14
- 239000000463 material Substances 0.000 description 8
- 241000238876 Acari Species 0.000 description 6
- NHDHVHZZCFYRSB-UHFFFAOYSA-N pyriproxyfen Chemical compound C=1C=CC=NC=1OC(C)COC(C=C1)=CC=C1OC1=CC=CC=C1 NHDHVHZZCFYRSB-UHFFFAOYSA-N 0.000 description 6
- FJDPATXIBIBRIM-UHFFFAOYSA-N cyphenothrin Chemical compound CC1(C)C(C=C(C)C)C1C(=O)OC(C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 FJDPATXIBIBRIM-UHFFFAOYSA-N 0.000 description 5
- 238000012360 testing method Methods 0.000 description 5
- 241000257226 Muscidae Species 0.000 description 4
- ISRUGXGCCGIOQO-UHFFFAOYSA-N Rhoden Chemical compound CNC(=O)OC1=CC=CC=C1OC(C)C ISRUGXGCCGIOQO-UHFFFAOYSA-N 0.000 description 4
- 235000019485 Safflower oil Nutrition 0.000 description 4
- 239000004615 ingredient Substances 0.000 description 4
- 238000000465 moulding Methods 0.000 description 4
- 235000005713 safflower oil Nutrition 0.000 description 4
- 239000003813 safflower oil Substances 0.000 description 4
- FJDPATXIBIBRIM-QFMSAKRMSA-N (1R)-trans-cyphenothrin Chemical compound CC1(C)[C@H](C=C(C)C)[C@H]1C(=O)OC(C#N)C1=CC=CC(OC=2C=CC=CC=2)=C1 FJDPATXIBIBRIM-QFMSAKRMSA-N 0.000 description 3
- 229920003345 Elvax® Polymers 0.000 description 3
- 206010061217 Infestation Diseases 0.000 description 3
- 239000003086 colorant Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000001125 extrusion Methods 0.000 description 3
- 239000011159 matrix material Substances 0.000 description 3
- RYUJRXVZSJCHDZ-UHFFFAOYSA-N 8-methylnonyl diphenyl phosphate Chemical compound C=1C=CC=CC=1OP(=O)(OCCCCCCCC(C)C)OC1=CC=CC=C1 RYUJRXVZSJCHDZ-UHFFFAOYSA-N 0.000 description 2
- 230000000749 insecticidal effect Effects 0.000 description 2
- 239000000155 melt Substances 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000000575 pesticide Substances 0.000 description 2
- 229920003023 plastic Polymers 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- 230000002035 prolonged effect Effects 0.000 description 2
- 230000004580 weight loss Effects 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 241000255925 Diptera Species 0.000 description 1
- 241000282324 Felis Species 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- 229920003347 Microthene® Polymers 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 241001674048 Phthiraptera Species 0.000 description 1
- 239000005927 Pyriproxyfen Substances 0.000 description 1
- 241001481696 Rhipicephalus sanguineus Species 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 239000001055 blue pigment Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000031902 chemoattractant activity Effects 0.000 description 1
- 235000005687 corn oil Nutrition 0.000 description 1
- 239000002285 corn oil Substances 0.000 description 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 230000002538 fungal effect Effects 0.000 description 1
- 230000000855 fungicidal effect Effects 0.000 description 1
- 238000001746 injection moulding Methods 0.000 description 1
- 239000004611 light stabiliser Substances 0.000 description 1
- 239000000314 lubricant Substances 0.000 description 1
- 210000003739 neck Anatomy 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 1
- 239000010452 phosphate Substances 0.000 description 1
- 239000004014 plasticizer Substances 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 239000001062 red colorant Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/08—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
- A01N25/10—Macromolecular compounds
Definitions
- the present invention is directed to a pest control system comprising a low melting point polymer or copolymer, high levels of a solid fatty acid, and active compounds to produce a solid slow release generator of the active compounds.
- stearic acid is used in polymers as a process lubricant and an anti-block agent because of this property.
- the compound becomes very difficult or impossible to process on conventional equipment such as an extruder or injection molding machine. This is due to the vast differences in melting points of stearic acid and the polymers plus the incompatibility between the two materials.
- the stearic acid lubricates to the extent that the compound simply turns in the barrel of the extruder or molding machine. If a low melt polymer conventional pellet is used, the same incompatibility is demonstrated when higher levels (above about 2%) of stearic acid is used.
- the present invention is directed to a pest control system comprising a pest control formulation comprising a low melting polymer or copolymer (that is, a polymer or copolymer having a melt temperature of below 250°F (121 °C), preferably below 200°F (93°C)), high levels of a solid fatty acid, and one or more active agents to produce a solid slow release generator of the active agents.
- a pest control formulation comprising a low melting polymer or copolymer (that is, a polymer or copolymer having a melt temperature of below 250°F (121 °C), preferably below 200°F (93°C)), high levels of a solid fatty acid, and one or more active agents to produce a solid slow release generator of the active agents.
- High levels of a solid fatty acid is defined as from about 5 wt% to about 50 wt%, preferably from about 15 wt% to about 30 wt%, of the total formulation.
- the system is useful for making articles such as animal collars, ear tags, pest strips or blocks, and the like, for releasing the active agent from the article over an extended or prolonged period of time.
- An "extended or prolonged period of time” is defined as a period of activity longer than the period of activity exhibited by the raw active ingredient alone.
- the present invention is further directed to a method for preparing a polymeric pest control system comprising high levels of a solid fatty acid, the method comprising combining an active agent with from about 5 wt% to about 50 wt% of the solid fatty acid, heating the combination to a liquid state, and then adding the combination to granules of small irregularly shaped particles of, or powder of a low melting polymer or copolymer to make a dry blend.
- This dry blend may then be processed into a shape on a conventional extruder or molding machine at low temperatures.
- the resulting active agent generator is formed by extrusion or molding the mix into any desired shape such as a flea and tick collar for animals, a film covering for preventing bacteria or fungal growth on beds, etc.
- fatty acid or “solid fatty acid” useful in the present invention is any fatty acid of from about 16 to about 36 carbon atoms which is a solid at room temperature.
- fatty acids include, but are not limited to, stearic, palmitic, margaric , nonadecanoic, arachidic, heneicosanoic, dehenic, tricosanoic, tetracosanoic, pentacosanoic, cerotic fatty acids and mixtures thereof.
- the solid fatty acid is present in the formulation of the invention in an amount of from about 5 wt% to about 50 wt%, preferably from about 15 wt% to about 30 wt%.
- the "low melting polymer or copolymer” is selected from those polymers or copolymers having a melt temperature of below 250°F (121°C), preferably below 200°F (93°C).
- Examples of polymers and copolymers useful in the present invention include, but are not limited to, polyethylene, polyvinyl acetate, polyethylene, ethylene acid copolymers, ethylene-vinyl acetate copolymers, ethylene acrylates, polyurethanes, styrene-butadiene, polyvinyl acetate, polyvinyl butyral, and mixtures and copolymers thereof.
- the polymer or copolymer is used, partially or wholly, in the form of granules, small irregularly shaped particles or powder.
- Conventional pellets of polymers are very difficult to work with in this invention and can only constitute a small percentage (no greater than about 15 wt% and preferably below about 10 wt%) of the total amount of polymer or copolymer, if they are used at all.
- the low melting polymer or copolymer is present in the formulation of the invention in an amount of from about 40 wt% to about 80 wt%, preferably from about 50 wt% to about 70 wt%, of which at least about 40 wt% is in the form of granules, small irregularly shaped particles or powder.
- the pest control active agent may be an insecticide, bactericide, fungicide, acaricide, attractant, repellent, any other biologically active ingredient that is compatible with the other components of the pest control system and mixtures thereof.
- the active agent is chosen from any active agent known to be useful in the control of insect or acarid pests.
- Exemplary pesticides and repellents which are effective against horn flies, face flies, stable flies, house flies, mosquitoes, lice, ticks, and mites are bioresmethrin, permethrin, tetramethrin, cypermethrin, decamethrin, pyrethrins, resmethrin, cyhalothrin, allethrin, dichlorvos, carbar l, naled, citrus oils, citronella oil, pine oil, stirofos, fenvalerate, stabilene, benzyl benzoate, methyl nonyl ketone, N-butylacetanilide, di-n-propyl isocinchomeronate, 2-octylthioethanol, dimethyl carbate, dimethyl phthalate, N,N- diethyl-m-toluamide, and 2,3:4,5-bis (2-butylene)-t
- synergists include piperonyl butoxide and N-octyl bicycloheptene dicarboximide.
- the active agent may be a liquid or a solid at room temperature.
- the pest control active agent and the solid fatty acid are mixed together at a predetermined ratio, with the proviso that the fatty acid is present at a high level.
- the amount of fatty acid in the formulation should be at least about 5 wt%, preferably at least about 15 wt%.
- the active agent/fatty acid mixture is then heated to a liquid state and added to granules of, small irregularly shaped particles of, or powder form of a low melting polymer or copolymer to make a dry blend.
- This dry blend formulation may then be processed into a shaped article, such as a pet collar or an ear tag or the like, on a conventional extruder or molding machine at low temperatures (that is, at temperatures that will melt the low melting polymer or copolymer, which is generally below about 250° F (121 °C)) by methods known in the art.
- the article should be cooled to room temperature as quickly as possible. In some cases when the article is not quickly cooled, there is excessive bloom on the surface, which can flake off. When this happens, the article can be annealed at 140°F (60°C) as a post operation to prevent the excessive bloom. (60°C)
- Additional components may optionally be included in the pest control system of the invention.
- Such optional ingredients can include, but are not limited to, plasticizers, synergists, fragrances, coloring agents, preservatives, antioxidants, light stabilizers, and the like.
- the active agent After being processed into the desired shape, the active agent will, together with the solid fatty acid, bloom to the surface of the article, making the active agent available to an environment, such as an animal for example, for pest control purposes, such as, for example, the control of insects and/or acarids on the animal.
- the fatty acid / active agent combination blooms to the surface and stops until a part of the surface material is removed. When the surface material is removed, it is replaced by more of the combination of the fatty acid / active agent from the inter-matrix of the plastic.
- Table 1 The formulation in Table 1 is prepared, and is then formed into an insecticidal dog collar, as follows:
- Microthene ® Polymer MU 760-00 ethylene-vinyl acetate copolymer, ground powder, melt index: 32 (EMI), particle size: 35 mesh) - Equistar Chemicals, LP. Colorant - Day Glow Color Corp
- the Gokilaht, safflower oil and stearic acid are weighed together. Heat is applied and the mixture brought to a liquid state at 165 °F (74°C). 2. The polymer is weighed and placed into a mixing vessel.
- liquid active agent/stearic acid mixture is slowly added to the polymer while mixing.
- the blend is then extruded or molded into the shape desired, which, in this Example was a dog collar.
- the dogs were infested with fleas (Ctenocephales felis) and ticks (Rhipicephalus sanguineus) on the day before treatment and then re-infested weekly thereafter, each re-infestation to be made approximately 24 hours before the first of the next series of flea and tick counts.
- Flea and tick timed finger counts were performed at 24 and 48 hours after treatment and at 24 hours after each re-infestation.
- Comb counts, by removing and discarding all fleas and ticks, were performed at 72 hours after treatment and after each re-infestation.
- EXAMPLE 2 The formulation in Table 2 is prepared, following the procedures of Example 1 :
- Nylar ® comprises approximately 50% by weight pyriproxyfen and approximately 50% by weight corn oil and is available from MGK Company.
- the material of the above formulation was subjected to a weigh loss test to ascertain if the non-polymer materials would release from the polymer matrix.
- the test consisted of extruding the material into dog collars, weighing the collars, wiping the surface of the collars with a clean paper towel and reweighing. The weight difference from each wiping demonstrates the weight loss as it might happen in actual use.
- a commercial cat pest control collar was similarly tested, as a comparison. While the weight loss of the collar of this invention was lower overall than that of the commercial collar, it followed the same profile of continuous loss over the course of the 25-day study. Also, while it was impossible in this study to ascertain the percent of active agents being released by the wipe test, visual observations show that the released material was a mixture of the oil phase materials and stearic acid.
- EXAMPLE 4 The formulation in Table 4 is prepared, and is then formed into an insecticidal dog collar, as follows:
- Elvax ethylene-vinyl acetate copolymer; conventional pellets
- the Gokilaht, phosflex, stearic acid and Nylar are weighed and added to a heatable mixing vessel. The materials are heated to 165 °F (74°C) and mixed until a honogenous solution is achieved.
- the MU 760-00 and the Elvax 150 polymers are weighed, placed into a mixing vessel and blended to uniformity.
- the liquids should be applied to the polymer powder while the polymers are being mixed, so as not to cause large lumps to form. This should be done far enough in advance of extrusion (generally about 24 hours is sufficient) so that the liquids can solidify and a free-flowing powder is achieved.
- the resulting formulation was extruded into dog collars.
- the Extrusion Profile is:
Landscapes
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Agronomy & Crop Science (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Description
Claims
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45868203P | 2003-03-28 | 2003-03-28 | |
PCT/US2004/009892 WO2004086862A2 (en) | 2003-03-28 | 2004-03-29 | Solid pest control system |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1613154A2 true EP1613154A2 (en) | 2006-01-11 |
EP1613154A4 EP1613154A4 (en) | 2011-07-27 |
Family
ID=35464382
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP04758580A Withdrawn EP1613154A4 (en) | 2003-03-28 | 2004-03-29 | Solid pest control system |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1613154A4 (en) |
TW (1) | TW200500006A (en) |
ZA (1) | ZA200508707B (en) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1480125A (en) * | 1974-02-07 | 1977-07-20 | Dow Chemical Co | Method of incorporating low-melting pesticidal materials into solid polymers |
US4544547A (en) * | 1980-10-22 | 1985-10-01 | Bayer Aktiengesellschaft | Ectoparasiticide-containing polyurethanes |
FR2649584A1 (en) * | 1989-07-12 | 1991-01-18 | Arrigoni Patrice | New process for the production of devices adapted to the protection of domestic animals and device thus produced |
EP0763325A1 (en) * | 1995-07-10 | 1997-03-19 | Sumitomo Chemical Company, Limited | Resin composition and molded product thereof |
-
2004
- 2004-03-26 TW TW093108278A patent/TW200500006A/en unknown
- 2004-03-29 EP EP04758580A patent/EP1613154A4/en not_active Withdrawn
-
2005
- 2005-10-27 ZA ZA200508707A patent/ZA200508707B/en unknown
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1480125A (en) * | 1974-02-07 | 1977-07-20 | Dow Chemical Co | Method of incorporating low-melting pesticidal materials into solid polymers |
US4544547A (en) * | 1980-10-22 | 1985-10-01 | Bayer Aktiengesellschaft | Ectoparasiticide-containing polyurethanes |
FR2649584A1 (en) * | 1989-07-12 | 1991-01-18 | Arrigoni Patrice | New process for the production of devices adapted to the protection of domestic animals and device thus produced |
EP0763325A1 (en) * | 1995-07-10 | 1997-03-19 | Sumitomo Chemical Company, Limited | Resin composition and molded product thereof |
Non-Patent Citations (1)
Title |
---|
See also references of WO2004086862A2 * |
Also Published As
Publication number | Publication date |
---|---|
EP1613154A4 (en) | 2011-07-27 |
TW200500006A (en) | 2005-01-01 |
ZA200508707B (en) | 2006-11-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
US5437869A (en) | Pest control system | |
AU626561B2 (en) | Terrestrial delivery compositions | |
EP0367140B1 (en) | Controlled release insect pest repellent | |
JP5258115B2 (en) | Insect repellent resin composition and sustained-release insect repellent molded article obtained therefrom | |
US20060264402A1 (en) | Pest control formulation | |
AU679692B2 (en) | Solid crop protection formulation | |
AU700100B2 (en) | Resin composition and molded product thereof | |
US20040191290A1 (en) | Solid pest control system | |
CA2048543C (en) | Processes and agents for combating fleas | |
EP0338821B1 (en) | Devices and means for applying substances externally to animals | |
JP3336714B2 (en) | Insect repellent resin composition | |
EP1613154A2 (en) | Solid pest control system | |
JP5648279B2 (en) | Polymer composition and molded article comprising the same | |
JP5648280B2 (en) | Polymer composition and molded article comprising the same | |
RU2289925C1 (en) | Rodenticide agent | |
JP2011127018A (en) | Polymer composition and molded article comprising the same | |
JP5604861B2 (en) | Molded body comprising polymer composition | |
US20230345934A1 (en) | Solid Composite Matrix for Prolonged Delivery of Active Agents | |
JP2011528715A (en) | Devices and methods for controlling insects | |
EP2152242A1 (en) | Pest control formulation | |
ZA200508748B (en) | Pest control formulation and dispenser | |
JP2024055605A (en) | Resin composition containing liquid functional additive | |
JP2004067960A (en) | 4-methyl-1-pentene polymer type insect-controlling resin composition and insect control molding | |
Houghton | Controlled Release Pellet Formulation |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20051028 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL LT LV MK |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: KELLEY, DONALD, W., |
|
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20110629 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A01N 25/34 20060101ALI20110623BHEP Ipc: A01N 25/10 20060101AFI20050119BHEP |
|
17Q | First examination report despatched |
Effective date: 20120503 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20121114 |