EP1578760A4 - Compositions et methodes de diagnostic et de traitement de tumeurs - Google Patents
Compositions et methodes de diagnostic et de traitement de tumeursInfo
- Publication number
- EP1578760A4 EP1578760A4 EP03749460A EP03749460A EP1578760A4 EP 1578760 A4 EP1578760 A4 EP 1578760A4 EP 03749460 A EP03749460 A EP 03749460A EP 03749460 A EP03749460 A EP 03749460A EP 1578760 A4 EP1578760 A4 EP 1578760A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- compositions
- tumor
- diagnosis
- treatment
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41016602P | 2002-09-11 | 2002-09-11 | |
US410166P | 2002-09-11 | ||
PCT/US2003/027894 WO2004024064A2 (fr) | 2002-09-11 | 2003-09-05 | Compositions et methodes de diagnostic et de traitement de tumeurs |
Publications (3)
Publication Number | Publication Date |
---|---|
EP1578760A2 EP1578760A2 (fr) | 2005-09-28 |
EP1578760A4 true EP1578760A4 (fr) | 2007-07-11 |
EP1578760B1 EP1578760B1 (fr) | 2014-02-12 |
Family
ID=31994078
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP03752035A Expired - Lifetime EP1546182B1 (fr) | 2002-09-11 | 2003-09-05 | Compositions et procede de diagnostic et de traitement des tumeurs |
EP03749460.6A Expired - Lifetime EP1578760B1 (fr) | 2002-09-11 | 2003-09-05 | Compositions et methodes de diagnostic et de traitement de tumeurs |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP03752035A Expired - Lifetime EP1546182B1 (fr) | 2002-09-11 | 2003-09-05 | Compositions et procede de diagnostic et de traitement des tumeurs |
Country Status (10)
Country | Link |
---|---|
US (3) | US20120045390A1 (fr) |
EP (2) | EP1546182B1 (fr) |
JP (4) | JP2006517387A (fr) |
AT (1) | ATE494296T1 (fr) |
AU (3) | AU2003268494A1 (fr) |
CA (2) | CA2498000C (fr) |
DE (1) | DE60335636D1 (fr) |
ES (2) | ES2359055T3 (fr) |
SI (1) | SI1546182T1 (fr) |
WO (2) | WO2004024064A2 (fr) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20120045390A1 (en) * | 2002-09-11 | 2012-02-23 | Genentech, Inc. | Composition and Methods for the Diagnosis and Treatment of Tumor |
WO2006034300A2 (fr) * | 2004-09-17 | 2006-03-30 | Cornell Research Foundation, Inc. | Kinases greatwall et leurs utilisations |
CN101223187A (zh) * | 2004-11-24 | 2008-07-16 | 萨拉普托斯股份公司 | 用作双重胱天蛋白酶-2/-6抑制剂的新肽及其生物学应用 |
CN102618642B (zh) * | 2004-12-08 | 2014-12-31 | 安万特药物公司 | 测量对多西他赛抗药性或敏感性的方法 |
JP2008154573A (ja) * | 2006-03-31 | 2008-07-10 | Toyobo Co Ltd | 可溶性グルコースデヒドロゲナーゼ(gdh)を含む組成物の安定性を向上する方法 |
US20100119529A1 (en) * | 2006-05-12 | 2010-05-13 | Furgeson Darin Y | Elastin-like polymer delivery vehicles |
WO2008017473A2 (fr) | 2006-08-08 | 2008-02-14 | Gunther Hartmann | Structure et utilisation d'oligonucléotides 5'-phosphate |
US20090011060A1 (en) * | 2007-07-06 | 2009-01-08 | Peter Koepke | Campsiandra angustifolia extract and methods of extracting and using such extract |
US7879369B2 (en) | 2007-09-18 | 2011-02-01 | Selvamedica, Llc | Combretum laurifolium Mart. extract and methods of extracting and using such extract |
AT506041A1 (de) * | 2007-12-10 | 2009-05-15 | Univ Innsbruck | Verfahren zur erhöhung der immunreaktivität |
JP5689413B2 (ja) | 2008-05-21 | 2015-03-25 | ライニッシュ フリードリッヒ−ウィルヘルムズ−ユニバーシタット ボン | 平滑末端を有する5’三リン酸オリゴヌクレオチドおよびその使用 |
EP2343294A1 (fr) | 2009-11-30 | 2011-07-13 | Bayer Schering Pharma AG | Triazolopyridines substituées |
EP2508530A1 (fr) | 2011-03-28 | 2012-10-10 | Rheinische Friedrich-Wilhelms-Universität Bonn | Purification d'oligonucléotides triphosphorylés au moyen d'étiquettes de capture |
EP2712870A1 (fr) | 2012-09-27 | 2014-04-02 | Rheinische Friedrich-Wilhelms-Universität Bonn | Nouveaux ligands de RIG-I et procédés pour les produire |
US10344052B2 (en) | 2013-03-14 | 2019-07-09 | Health Research, Inc. | Targeting peptides and uses thereof |
US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997022702A1 (fr) * | 1995-12-18 | 1997-06-26 | Sugen, Inc. | Diagnostic et traitement de troubles lies aux aur-1 et aur-2 |
WO2001009316A1 (fr) * | 1999-07-29 | 2001-02-08 | Helix Research Institute | Nouveaux genes codant la proteine kinase / proteine phosphatase |
WO2002086443A2 (fr) * | 2001-04-18 | 2002-10-31 | Protein Design Labs, Inc | Procedes de diagnostic du cancer du poumon, compositions et procedes de criblage de modulateurs du cancer du poumon |
WO2002101075A2 (fr) * | 2001-06-13 | 2002-12-19 | Millennium Pharmaceuticals, Inc. | Identification, evaluation, prevention et traitement du cancer du col de l'uterus : nouveaux genes, nouvelles compositions, nouvelles trousses et nouvelles methodes |
WO2002102235A2 (fr) * | 2001-06-18 | 2002-12-27 | Eos Biotechnology Inc. | Procedes de diagnostic du cancer ovarien, compositions et procedes de criblage de modulateurs du cancer ovarien |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6716575B2 (en) * | 1995-12-18 | 2004-04-06 | Sugen, Inc. | Diagnosis and treatment of AUR1 and/or AUR2 related disorders |
US5885803A (en) * | 1997-06-19 | 1999-03-23 | Incyte Pharmaceuticals, Inc. | Disease associated protein kinases |
WO2002016429A2 (fr) * | 2000-08-24 | 2002-02-28 | Genentech, Inc. | Compositions et procedes de diagnostic et traitement de tumeurs |
WO1999065928A2 (fr) * | 1998-06-19 | 1999-12-23 | Genzyme Corporation | Population de polynucleotides isoles de tissus mammaires tumoraux metastatiques ou non metastatiques |
CA2394803A1 (fr) * | 1999-11-24 | 2001-05-31 | Sugen, Inc. | Nouvelles proteines kinases humaines et enzymes analogues |
AU2001269726A1 (en) * | 2000-05-31 | 2001-12-11 | Chiron Corporation | Compositions and methods for treating neoplastic disease using chemotherapy and radiation sensitizers |
US6974667B2 (en) * | 2000-06-14 | 2005-12-13 | Gene Logic, Inc. | Gene expression profiles in liver cancer |
WO2002016581A2 (fr) * | 2000-08-24 | 2002-02-28 | Genentech, Inc. | Compositions et methodes pour le diagnostic et le traitement de tumeurs |
MXPA03001643A (es) * | 2000-08-24 | 2004-05-14 | Genentech Inc | Composiciones y metodos para el diagnostico y tratamiento de tumores. |
CA2427858A1 (fr) * | 2000-11-03 | 2002-05-10 | University Of Vermont And State Agricultural College | Methodes et compositions destinees a inhiber grb7 |
US20040029114A1 (en) * | 2001-01-24 | 2004-02-12 | Eos Technology, Inc. | Methods of diagnosis of breast cancer, compositions and methods of screening for modulators of breast cancer |
JP2004531249A (ja) * | 2001-02-14 | 2004-10-14 | プロテイン デザイン ラブス インコーポレイティド | 血管新生の診断方法、組成物、及び血管新生モジュレータのスクリーニング方法 |
WO2003042661A2 (fr) * | 2001-11-13 | 2003-05-22 | Protein Design Labs, Inc. | Methodes de diagnostic du cancer, compositions et methodes de criblage des modulateurs du cancer |
CA2467433A1 (fr) * | 2001-11-13 | 2003-05-22 | Eos Biotechnology, Inc. | Methodes de diagnostic du cancer, compositions et methodes de criblage des modulateurs du cancer |
EP1468118A4 (fr) * | 2002-01-31 | 2006-08-02 | Millennium Pharm Inc | Procedes et compositions pour le traitement du cancer |
US20120045390A1 (en) * | 2002-09-11 | 2012-02-23 | Genentech, Inc. | Composition and Methods for the Diagnosis and Treatment of Tumor |
-
2003
- 2003-09-05 US US10/526,806 patent/US20120045390A1/en not_active Abandoned
- 2003-09-05 AT AT03752035T patent/ATE494296T1/de active
- 2003-09-05 JP JP2004536117A patent/JP2006517387A/ja active Pending
- 2003-09-05 CA CA2498000A patent/CA2498000C/fr not_active Expired - Lifetime
- 2003-09-05 EP EP03752035A patent/EP1546182B1/fr not_active Expired - Lifetime
- 2003-09-05 CA CA2498004A patent/CA2498004C/fr not_active Expired - Lifetime
- 2003-09-05 ES ES03752035T patent/ES2359055T3/es not_active Expired - Lifetime
- 2003-09-05 WO PCT/US2003/027894 patent/WO2004024064A2/fr active Application Filing
- 2003-09-05 JP JP2004536115A patent/JP2005537810A/ja active Pending
- 2003-09-05 WO PCT/US2003/027886 patent/WO2004024063A2/fr active Application Filing
- 2003-09-05 AU AU2003268494A patent/AU2003268494A1/en not_active Abandoned
- 2003-09-05 DE DE60335636T patent/DE60335636D1/de not_active Expired - Lifetime
- 2003-09-05 SI SI200331964T patent/SI1546182T1/sl unknown
- 2003-09-05 AU AU2003270348A patent/AU2003270348B2/en not_active Expired
- 2003-09-05 ES ES03749460.6T patent/ES2456696T3/es not_active Expired - Lifetime
- 2003-09-05 EP EP03749460.6A patent/EP1578760B1/fr not_active Expired - Lifetime
- 2003-09-05 US US10/656,598 patent/US20040229232A1/en not_active Abandoned
-
2009
- 2009-12-24 JP JP2009293524A patent/JP2010131015A/ja active Pending
-
2010
- 2010-04-16 AU AU2010201526A patent/AU2010201526A1/en not_active Abandoned
-
2011
- 2011-08-11 JP JP2011175869A patent/JP2012046515A/ja active Pending
-
2013
- 2013-03-19 US US13/847,366 patent/US20130210116A1/en not_active Abandoned
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997022702A1 (fr) * | 1995-12-18 | 1997-06-26 | Sugen, Inc. | Diagnostic et traitement de troubles lies aux aur-1 et aur-2 |
WO2001009316A1 (fr) * | 1999-07-29 | 2001-02-08 | Helix Research Institute | Nouveaux genes codant la proteine kinase / proteine phosphatase |
WO2002086443A2 (fr) * | 2001-04-18 | 2002-10-31 | Protein Design Labs, Inc | Procedes de diagnostic du cancer du poumon, compositions et procedes de criblage de modulateurs du cancer du poumon |
WO2002101075A2 (fr) * | 2001-06-13 | 2002-12-19 | Millennium Pharmaceuticals, Inc. | Identification, evaluation, prevention et traitement du cancer du col de l'uterus : nouveaux genes, nouvelles compositions, nouvelles trousses et nouvelles methodes |
WO2002102235A2 (fr) * | 2001-06-18 | 2002-12-27 | Eos Biotechnology Inc. | Procedes de diagnostic du cancer ovarien, compositions et procedes de criblage de modulateurs du cancer ovarien |
Non-Patent Citations (1)
Title |
---|
DATABASE WPI Week 200164, Derwent World Patents Index; AN 2001-570286, XP002434491 * |
Also Published As
Publication number | Publication date |
---|---|
US20040229232A1 (en) | 2004-11-18 |
ES2359055T3 (es) | 2011-05-18 |
ES2456696T3 (es) | 2014-04-23 |
DE60335636D1 (de) | 2011-02-17 |
AU2003270348A1 (en) | 2004-04-30 |
JP2010131015A (ja) | 2010-06-17 |
ATE494296T1 (de) | 2011-01-15 |
JP2012046515A (ja) | 2012-03-08 |
EP1546182A4 (fr) | 2006-09-06 |
CA2498000A1 (fr) | 2004-03-25 |
AU2003270348B2 (en) | 2010-08-26 |
EP1546182A2 (fr) | 2005-06-29 |
EP1578760B1 (fr) | 2014-02-12 |
EP1578760A2 (fr) | 2005-09-28 |
EP1546182B1 (fr) | 2011-01-05 |
JP2005537810A (ja) | 2005-12-15 |
CA2498000C (fr) | 2015-01-20 |
US20130210116A1 (en) | 2013-08-15 |
AU2003268494A1 (en) | 2004-04-30 |
AU2010201526A1 (en) | 2010-05-06 |
JP2006517387A (ja) | 2006-07-27 |
US20120045390A1 (en) | 2012-02-23 |
WO2004024064A8 (fr) | 2005-07-21 |
WO2004024063A3 (fr) | 2004-10-14 |
SI1546182T1 (sl) | 2011-04-29 |
WO2004024064A2 (fr) | 2004-03-25 |
WO2004024063A2 (fr) | 2004-03-25 |
CA2498004C (fr) | 2013-06-11 |
CA2498004A1 (fr) | 2004-03-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MXPA04002593A (es) | Composiciones y metodos para el diagnostico y tratamiento de tumor. | |
MXPA03011985A (es) | Composiciones y metodos para el diagnostico y tratamiento de tumores. | |
MXPA05005107A (es) | Composiciones y metodos para el diagnostico y tratamiento de tumores. | |
MXPA03001645A (es) | Composiciones y metodos para el diagnostico y tratamiento de tumores. | |
ZA200702322B (en) | Compositions and methods for the diagnosis and treatment of tumor | |
WO2003088808A3 (fr) | Compositions et methodes permettant de diagnostiquer et de traiter une tumeur | |
SG155947A1 (en) | Compositions and methods for the diagnosis and treatment of tumor | |
WO2006110760A3 (fr) | Compositions et methodes de diagnostic et de traitement de tumeur | |
EP2067472A8 (fr) | Compositions et procédés pour le traitement et le diagnostic d'une tumeur | |
WO2004112829A3 (fr) | Compositions et procedes pour le diagnostic et le traitement de tumeurs d'origine gliale | |
MXPA05005223A (es) | Diaminotriazoles utiles como inhibidores de proteinas cinasas. | |
MY150531A (en) | Anti-cd79b antibodies and immunoconjugates and methods of use | |
WO2004024097A8 (fr) | Compositions et methodes de traitement de maladies de nature immune | |
WO2005049075A3 (fr) | Compositions et methodes de traitement d'une tumeur d'origine hematopoietique | |
TW200612918A (en) | Lonidamine analogs | |
EP1578760A4 (fr) | Compositions et methodes de diagnostic et de traitement de tumeurs | |
WO2002016581A3 (fr) | Compositions et methodes pour le diagnostic et le traitement de tumeurs | |
MXPA03001643A (es) | Composiciones y metodos para el diagnostico y tratamiento de tumores. | |
WO2005063299A3 (fr) | Compositions et methodes pour traitement des tumeurs d'origine hematopoietique | |
WO2006014335A3 (fr) | Compositions et procedes pour le traitement de lymphome non hodgkinien | |
WO2004096124A3 (fr) | Compositions et procedes pour le diagnostic et le traitement de tumeurs | |
EP1590666A4 (fr) | Compositions et procedes permettant d'ameliorer l'apoptose | |
MXPA05008293A (es) | Composiciones y metodos para el diagnostico y tratamiento de tumores. | |
MXPA03001644A (es) | Composiciones y metodos para el diagnostico y tratamiento de tumor. | |
WO2006081272A3 (fr) | Compositions et methodes de diagnostic et de traitement d'une tumeur |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20050404 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL LT LV MK |
|
DAX | Request for extension of the european patent (deleted) | ||
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12N 5/00 20060101ALI20070525BHEP Ipc: A01N 61/00 20060101ALI20070525BHEP Ipc: C12P 21/06 20060101ALI20070525BHEP Ipc: C07H 21/04 20060101ALI20070525BHEP Ipc: A61K 39/395 20060101ALI20070525BHEP Ipc: C07K 1/00 20060101AFI20070525BHEP Ipc: A61K 39/00 20060101ALI20070525BHEP |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20070611 |
|
PUAK | Availability of information related to the publication of the international search report |
Free format text: ORIGINAL CODE: 0009015 |
|
17Q | First examination report despatched |
Effective date: 20100611 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R079 Ref document number: 60345696 Country of ref document: DE Free format text: PREVIOUS MAIN CLASS: C07H0021020000 Ipc: C12N0009120000 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: C12P 21/06 20060101ALI20121211BHEP Ipc: C12N 5/00 20060101ALI20121211BHEP Ipc: C12N 9/12 20060101AFI20121211BHEP Ipc: C07K 1/00 20060101ALI20121211BHEP Ipc: A61K 39/395 20060101ALI20121211BHEP Ipc: C07H 21/04 20060101ALI20121211BHEP Ipc: A61K 39/00 20060101ALI20121211BHEP Ipc: A01N 61/00 20060101ALI20121211BHEP |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
INTG | Intention to grant announced |
Effective date: 20130620 |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
INTG | Intention to grant announced |
Effective date: 20130830 |
|
GRAS | Grant fee paid |
Free format text: ORIGINAL CODE: EPIDOSNIGR3 |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: FG4D |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: EP |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: REF Ref document number: 652171 Country of ref document: AT Kind code of ref document: T Effective date: 20140215 |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: NV Representative=s name: F. HOFFMANN-LA ROCHE AG, CH |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R096 Ref document number: 60345696 Country of ref document: DE Effective date: 20140320 |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: FG4D |
|
REG | Reference to a national code |
Ref country code: ES Ref legal event code: FG2A Ref document number: 2456696 Country of ref document: ES Kind code of ref document: T3 Effective date: 20140423 |
|
REG | Reference to a national code |
Ref country code: NL Ref legal event code: VDEP Effective date: 20140212 |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: MK05 Ref document number: 652171 Country of ref document: AT Kind code of ref document: T Effective date: 20140212 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: AT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140212 Ref country code: FI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140212 Ref country code: PT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140612 Ref country code: CY Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140212 Ref country code: SE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140212 Ref country code: NL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140212 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140212 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: EE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140212 Ref country code: RO Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140212 Ref country code: DK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140212 Ref country code: CZ Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140212 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R097 Ref document number: 60345696 Country of ref document: DE |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140212 |
|
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
26N | No opposition filed |
Effective date: 20141113 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R097 Ref document number: 60345696 Country of ref document: DE Effective date: 20141113 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LU Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140905 Ref country code: MC Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140212 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140212 |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: MM4A |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20140905 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BG Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140212 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20140513 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: HU Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO Effective date: 20030905 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 14 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 15 |
|
REG | Reference to a national code |
Ref country code: FR Ref legal event code: PLFP Year of fee payment: 16 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: TR Payment date: 20220902 Year of fee payment: 20 Ref country code: GB Payment date: 20220810 Year of fee payment: 20 Ref country code: DE Payment date: 20220615 Year of fee payment: 20 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: FR Payment date: 20220810 Year of fee payment: 20 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: IT Payment date: 20220929 Year of fee payment: 20 Ref country code: ES Payment date: 20221011 Year of fee payment: 20 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: CH Payment date: 20221001 Year of fee payment: 20 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R071 Ref document number: 60345696 Country of ref document: DE |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: PL |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: PE20 Expiry date: 20230904 Ref country code: ES Ref legal event code: FD2A Effective date: 20230927 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GB Free format text: LAPSE BECAUSE OF EXPIRATION OF PROTECTION Effective date: 20230904 Ref country code: ES Free format text: LAPSE BECAUSE OF EXPIRATION OF PROTECTION Effective date: 20230906 |