EP1573008A2 - Polynucleotides diriges contre la htert et utilisation de ces derniers - Google Patents

Polynucleotides diriges contre la htert et utilisation de ces derniers

Info

Publication number
EP1573008A2
EP1573008A2 EP03785567A EP03785567A EP1573008A2 EP 1573008 A2 EP1573008 A2 EP 1573008A2 EP 03785567 A EP03785567 A EP 03785567A EP 03785567 A EP03785567 A EP 03785567A EP 1573008 A2 EP1573008 A2 EP 1573008A2
Authority
EP
European Patent Office
Prior art keywords
polynucleotide
tumor
therapy
use according
carcinoma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP03785567A
Other languages
German (de)
English (en)
Inventor
Bernd Schwenzer
Uta Schmidt
Manfred P. Wirth
Kai KRÄMER
Susanne FÜSSEL
Axel Meye
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Technische Universitaet Dresden
Original Assignee
Technische Universitaet Dresden
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10306084A external-priority patent/DE10306084A1/de
Application filed by Technische Universitaet Dresden filed Critical Technische Universitaet Dresden
Publication of EP1573008A2 publication Critical patent/EP1573008A2/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La présente invention concerne des polynucléotides dirigés contre un gène d'une sous-unité catalytique de la télomérase humaine ainsi que l'utilisation de ces polynucléotides dans le diagnostic, la prophylaxie, l'atténuation, le contrôle de l'évolution de maladies associées à la croissance cellulaire, la différenciation cellulaire et/ou la division cellulaire, telles que des maladies tumorales.
EP03785567A 2002-12-06 2003-12-08 Polynucleotides diriges contre la htert et utilisation de ces derniers Withdrawn EP1573008A2 (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE10258117 2002-12-06
DE10258117 2002-12-06
DE10306084 2003-02-07
DE10306084A DE10306084A1 (de) 2002-12-06 2003-02-07 Gegen hTERT gerichtete Erkennungsmoleküle und die Verwendung dieser
PCT/DE2003/004114 WO2004053116A2 (fr) 2002-12-06 2003-12-08 Polynucleotides diriges contre la htert et utilisation de ces derniers

Publications (1)

Publication Number Publication Date
EP1573008A2 true EP1573008A2 (fr) 2005-09-14

Family

ID=32509753

Family Applications (1)

Application Number Title Priority Date Filing Date
EP03785567A Withdrawn EP1573008A2 (fr) 2002-12-06 2003-12-08 Polynucleotides diriges contre la htert et utilisation de ces derniers

Country Status (4)

Country Link
US (1) US20060127909A1 (fr)
EP (1) EP1573008A2 (fr)
AU (1) AU2003294653A1 (fr)
WO (1) WO2004053116A2 (fr)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5645986A (en) * 1992-05-13 1997-07-08 Board Of Reagents, The University Of Texas System Therapy and diagnosis of conditions related to telomere length and/or telomerase activity
US5489508A (en) * 1992-05-13 1996-02-06 University Of Texas System Board Of Regents Therapy and diagnosis of conditions related to telomere length and/or telomerase activity
US6093809A (en) * 1996-10-01 2000-07-25 University Technology Corporation Telomerase
US6444650B1 (en) * 1996-10-01 2002-09-03 Geron Corporation Antisense compositions for detecting and inhibiting telomerase reverse transcriptase
CA2294782A1 (fr) * 1997-07-01 1999-01-14 Cambia Biosystems Llc Genes et proteines telomerase de vertebres et leurs utilisations
ATE328079T1 (de) * 1998-01-08 2006-06-15 Chugai Pharmaceutical Co Ltd Neues gen mit einem revers-transkriptase-motiv
US6492171B2 (en) * 2000-05-16 2002-12-10 Isis Pharmaceuticals, Inc. Antisense modulation of TERT expression
US20050153916A1 (en) * 2001-05-18 2005-07-14 Sirna Therapeutics, Inc. RNA interference mediated inhibition of telomerase gene expression using short interfering nucleic acid (siNA)
US20060257851A1 (en) * 2002-11-26 2006-11-16 Itzhak Bentwich Bioinformatically detectable group of novel viral regulatory genes and uses thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See references of WO2004053116A2 *

Also Published As

Publication number Publication date
AU2003294653A8 (en) 2004-06-30
WO2004053116A3 (fr) 2004-09-16
AU2003294653A1 (en) 2004-06-30
WO2004053116A2 (fr) 2004-06-24
US20060127909A1 (en) 2006-06-15

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Inventor name: MEYE, AXEL

Inventor name: FUESSEL, SUSANNE

Inventor name: KRAEMER, KAI

Inventor name: WIRTH, MANFRED, P.

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